Chemical Formula | C7H4ClF3 |
Molecular Weight | 180.55 |
Appearance | Colorless to light yellow liquid |
Odor | Pungent odor |
Boiling Point | 139 - 141 °C |
Melting Point | -48 °C |
Density | 1.329 g/cm³ (at 20 °C) |
Solubility In Water | Insoluble |
Vapor Pressure | 1.33 kPa (at 29.5 °C) |
Flash Point | 38 °C |
Refractive Index | 1.4542 (at 20 °C) |
What are the main uses of O-Chlorotrifluorotoluene?
O-chlorotrifluorotoluene is also an organic compound. It has a wide range of uses and has a significant position in the chemical industry.
Bearing the brunt, it is a key intermediate for the synthesis of many pesticides. Due to its unique chemical structure and properties, it can react with a variety of reagents to generate pesticides with high insecticidal and herbicidal properties. For example, specific insecticides can be prepared through a series of reactions, which can precisely act on the nervous system of pests, effectively kill common crop pests, ensure a good harvest of crops, and protect farmland from insect infestation.
Furthermore, it also has important uses in the field of pharmaceutical synthesis. It can be used as a starting material to participate in the construction of complex drug molecules. With the help of chlorine atoms and trifluoromethyl, it can change the physical and chemical properties of drug molecules, such as improving drug fat solubility, promoting drug absorption and distribution in the body, and helping to develop more effective drugs that are more easily absorbed by the human body, contributing to the development of medicine.
In addition, in the field of materials science, O-chlorotrifluorotoluene can also be used. It can be used to synthesize special performance polymer materials, such as fluoropolymers. Such polymers exhibit excellent chemical stability, weather resistance and low surface energy due to the introduction of fluorine atoms, and are widely used in coatings, plastics and other industries. The paint made can provide good protection for the surface of the object and resist the erosion of the harsh environment; the plastic made can be used to make the shell of high-end electronic products, which has the advantages of lightness and durability.
To sum up, O-chlorotrifluorotoluene plays an important role in pesticides, medicine, materials science and other fields, promoting the continuous development of various industries and bringing many conveniences and progress to human production and life.
What are the physical properties of O-Chlorotrifluorotoluene?
O-chlorotrifluorotoluene, an organic compound. Its physical properties are quite specific, with the following ends.
Looking at its appearance, under room temperature and pressure, it is often a colorless to light yellow transparent liquid, clear and shiny, like morning dew on the tip of a leaf, clear and crystal clear.
Smell the smell, with a pungent aroma, this smell is fierce, can stimulate people's olfactory nerves, impressive.
In terms of its boiling point, it is about 139-141 ° C. When the temperature reaches this point, this substance disappears like ice in the warm sun, gradually converts from liquid to gas, and rises.
Its melting point is very low, about -48 ° C. At this low temperature, the substance condenses into a solid state, just like the ice of winter, strong and cold.
As for the density, it is about 1.37g/cm ³, which is heavier than water. If it is poured into water, it is like a stone sinking into the abyss, sinking straight down.
Solubility is also an important physical property. In water, it dissolves very little, just like oil floating in water, and it is difficult to blend. However, many organic solvents, such as ethanol, ether, acetone, etc., can dissolve in any ratio, just like water emulsion blending, harmonious.
In addition, its volatility should not be underestimated. In a normal temperature environment, it will evaporate slowly, and the molecules will dissipate in the air, like light smoke, gradually reducing their amount.
These physical properties have a crucial impact in many fields such as chemical engineering and medicine, which is related to the wide range of applications and the difficulty of processing.
What is O-Chlorotrifluorotoluene production method?
The method of preparing o-chlorotoluene used to follow several paths in the past. One is to use o-chlorotoluene as a group, through chlorination and fluorination sequence. During chlorination, chlorine is reacted with o-chlorotoluene with a suitable catalyst, such as iron or copper, to obtain o-chlorobenzyl chloride. This step requires temperature control and chlorine flow rate to prevent the formation of polychlorinated compounds. Then, anhydrous hydrogen fluoride is used as a fluorinating agent, and at appropriate pressure and temperature, o-chlorobenzyl is chlorinated to obtain o-chlorotoluene. This way the raw material is easy to induce, but the chlorination step or many by-products are produced, which affects the purity and yield of the product.
Second, with o-chlorobenzoic acid as the starting material, the acid chloride is first prepared, and then reacted with fluorinating agents, such as antimony trifluoride or antimony pentafluoride, by Swarts (Swarts). This reaction condition is harsher, requiring an anhydrous environment and high temperature, but the selectivity is still good, and high-purity o-chlorotrifluorotoluene can be obtained.
And with o-chloroaniline as the raw material, chlorine atoms are introduced through diazotization and Sandmeyer reaction, and then fluorinated to obtain the target product. This path step is complicated, but in specific situations, it may have unique advantages and can precisely control the position of the substituent. < Br >
Each method has its advantages and disadvantages. In actual production, the optimal method should be selected according to the availability of raw materials, cost, equipment conditions and product purity requirements, etc., in order to achieve the purpose of efficient preparation of o-chlorotrifluorotoluene.
O-Chlorotrifluorotoluene need to pay attention to when storing and transporting
O-chlorotrifluorotoluene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First word storage. This substance should be placed in a cool and ventilated warehouse. Because of the cool and ventilated place, it can be prevented from being decomposed by heat or causing other chemical changes. If it is heated, it may cause its volatilization to accelerate, or even have the risk of combustion and explosion. The temperature of the warehouse should be controlled within a reasonable range, not too high. And it must be kept away from fire and heat sources. Open flames are strictly prohibited to avoid igniting this chemical.
Furthermore, the storage place should be kept dry and must not be humid. Because of its reaction with water, the quality will be damaged, the use will be affected, and even dangerous. Storage containers are also crucial. A well-sealed container must be selected to prevent leakage. And the material of the container should be compatible with O-chlorotrifluorotoluene and do not chemically react with it to ensure safe storage.
As for transportation. Before transportation, make sure that the packaging is complete and sealed. The packaging material should be strong and can withstand a certain external force to avoid leakage caused by damage to the container during transportation. The transportation vehicle should also be clean and dry, and there should be no other substances that may react with it. During transportation, the speed should be stable, and no sudden braking or sharp turns should be made to avoid packaging collision damage. At the same time, the transportation personnel must undergo professional training and be familiar with the characteristics of O-chlorotrifluorotoluene and emergency treatment methods. If there is a leak during transportation, we can respond promptly and properly to ensure the safety of personnel and the environment.
O-Chlorotrifluorotoluene impact on the environment and human body
O-chlorotrifluorotoluene is an organic compound. Although its impact on the environment and the human body has not been discussed in detail in ancient times, it can be said in today's scientific view.
In the environment, this substance is quite stable and difficult to degrade naturally, or accumulates in soil and water bodies. If released into the atmosphere, or participates in photochemical reactions, it affects the quality of the atmosphere, and because of its fluorine and chlorine elements, it may have potential damage to the ozone layer. In aquatic ecology, or cause poisoning to aquatic organisms, affect their growth and reproduction, and disrupt the ecological balance. In terrestrial ecology, or pass through the food chain, enrich, and endanger higher organisms.
As for the human body, it has certain toxicity. After breathing, skin contact or accidental ingestion, or irritate the respiratory tract, skin and eyes, causing discomfort. Long-term exposure, or damage to liver, kidney and other organ functions, because of fat-soluble, easy to accumulate in adipose tissue. What's more, it may have potential carcinogenicity, although it has not yet been conclusively determined, but research has found relevant clues. In conclusion, O-chlorotrifluorotoluene poses a latent risk to both the environment and the human body, and its use and emissions should be properly controlled with caution.