M Bromotrifluorotoluene
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
m-Bromotrifluorotoluene
Chemical Formula C7H4BrF3
Molecular Weight 225.005
Appearance Colorless to light yellow liquid
Boiling Point 173 - 175 °C
Melting Point -48 °C
Density 1.58 g/cm³
Flash Point 62 °C
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Vapor Pressure 1.33 kPa (47.2 °C)
Refractive Index 1.475 (20 °C)
FAQ

What are the main uses of m-Bromotrifluorotoluene?

M-Bromotrifluorotoluene, or m-bromotrifluorotoluene, has a wide range of main uses. In the field of organic synthesis, this is a key intermediate. It can be used to prepare many fluorine-containing fine chemicals, such as pesticides, medicines and dyes.

Let's talk about pesticides first. With this as the starting material, through a series of chemical reactions, efficient and low-toxic pesticide varieties can be created. Such pesticides have excellent pest control effects, but have little impact on the environment and contribute to sustainable agricultural development. For example, fluoride-containing pesticides with specific structures can be synthesized. Their unique chemical structure can precisely act on the physiological target of pests, causing the pest's nervous system to be disrupted and then died, while they are relatively safe for beneficial insects and other non-target organisms.

In the field of medicine, m-Bromotrifluorotoluene is also crucial. It can be used to synthesize a variety of new drugs. Because of its fluoride atoms, it can significantly change the physical and chemical properties of drug molecules, such as improving the lipid solubility of drugs, promoting drugs to more easily penetrate biofilms, enhancing the interaction between drugs and receptors, thereby improving the bioavailability and efficacy of drugs. For example, in the development of anti-cancer drugs, fluorinated drug molecules based on this can more effectively act on specific targets of cancer cells and inhibit the growth and spread of cancer cells.

Furthermore, in the dye industry, it can be used to synthesize fluorinated dyes with bright colors, excellent light resistance and washable properties. Such dyes are used in textile, printing and dyeing and other industries, which can give fabrics unique colors and properties and meet people's needs for high-quality textiles.

In summary, m-Bromotrifluorotoluene plays an irreplaceable role in many fields such as organic synthesis, pesticides, medicine and dyes due to its special chemical structure, and is of great significance to promoting the development of related industries.

What are the physical properties of m-Bromotrifluorotoluene?

M - Bromotrifluorotoluene, which is m-bromotrifluorotoluene, is one of the organic compounds. Its physical properties are as follows:
- ** Properties **: Usually in the state of colorless to light yellow transparent liquid, the appearance is pure and has a specific luster. This form is conducive to smooth participation as a raw material or solvent in many chemical reactions and industrial processes.
- ** Odor **: It emits a special odor, although not strong and pungent, it can still be clearly perceived in confined spaces or at high concentrations. Its unique odor may be used as a basis for preliminary identification of the substance.
- ** Boiling point **: The boiling point is about 148 - 150 ° C. This boiling point condition determines its gasification temperature during heating, which is of great significance in distillation, separation and other operations. The appropriate boiling point makes it possible to realize its gas-liquid conversion under conventional heating conditions, which is convenient for separation from other substances with large differences in boiling points.
- ** Melting point **: The melting point is around -34 ° C. The lower melting point causes the substance to be liquid at room temperature, and it can maintain good fluidity without additional heating, which is conducive to storage, transportation and mixing operations in various reaction systems.
- ** Density **: The density is about 1.59 g/mL, which is greater than the density of water. This characteristic determines that when mixed with liquids with low density such as water, they will sink to the bottom. When it comes to operations such as liquid-liquid separation, effective separation can be carried out according to this density difference.
- ** Solubility **: It is difficult to dissolve in water. Because its molecular structure contains hydrophobic groups such as trifluoromethyl, the force between it and water molecules is weak. But it is soluble in common organic solvents, such as ethanol, ether, benzene, etc. In organic synthesis, it can build a homogeneous reaction system with its good solubility in organic solvents to promote efficient reaction.
- ** Vapor pressure **: It has a certain vapor pressure at room temperature and will slowly evaporate into the air. Although the evaporation rate is not fast, it is still necessary to pay attention during storage and use to prevent concentration changes or environmental pollution due to long-term evaporation, and also to pay attention to the potential safety risks of its steam.

Is m-Bromotrifluorotoluene chemically stable?

In the case of m-Bromotrifluorotoluene, there are benzene compounds. Its chemical properties are low. In its molecules, the benzene and benzene sites are reduced due to the absorptive effect of trifluoromethyl, which makes the benzene substitution anti-benzene and benzene sites, and the activity of the benzene phase is slightly higher.

Trifluoromethyl groups can reduce the density of benzene clouds, resulting in the inverse activity of m-Bromotrifluorotoluene. In addition, the effect of the bromine atom itself also decreases the density of benzene clouds, which affects its chemical properties.

However, due to the joint action of benzene, trifluoromethyl, and bromine atoms, its chemical properties are certain under general conditions. In the absence of specific components such as oxidation and nuclear reagent, the molecular reagent is not easy to modify.

However, under the appropriate reagent, the m-Bromotrifluorotoluene can still be reactive such as nuclear reagent, nuclear reagent, etc., only special reagents and catalysts are required. In addition, the phase is determined by some high-activity compounds, and the m-Bromotrifluorotoluene.

What is m-Bromotrifluorotoluene production method?

M-Bromotrifluorotoluene, that is, m-bromotrifluorotoluene, has the following common preparation methods:

First, m-toluidine is used as the starting material. Shilling m-toluidine reacts with hydrofluoric acid and sodium nitrite, and then reacts with cuprous bromide to obtain m-trifluoromethyl diazonium salt. Second, m-bromotoluene is used as the raw material. Under specific reaction conditions, the fluorination reaction of m-bromotoluene is carried out by using fluorinating reagents such as cobalt trifluoride, so that the methyl group is converted into trifluoromethyl group, and m-bromotrifluorotoluene is finally obtained. This reaction needs to control the reaction temperature and the amount of fluorination reagent. Due to the strong oxidation of cobalt trifluoride, improper reaction conditions are prone to side reactions such as excessive fluorination, which affect the purity and yield of the product.

Third, trifluorotoluene is used as the raw material. In the presence of a catalyst, trifluorotoluene is substituted with bromine. Common catalysts such as iron or iron salts, during the reaction, the meta-hydrogen atom of trifluoromethyl is replaced by a bromine atom to form m-bromotrifluorotoluene. The reaction requires attention to the dropwise addition rate of bromine and the reaction temperature to prevent the formation of polybrominated by-products. At the same time, the remaining bromine and catalyst need to be properly disposed of after the reaction to avoid environmental pollution.

These methods have their own advantages and disadvantages. In actual production, it is necessary to comprehensively consider the cost of raw materials, reaction conditions, product purity and yield, and carefully select the appropriate preparation method to achieve efficient, economical and environmentally friendly production goals.

What are the precautions in storage and transportation of m-Bromotrifluorotoluene?

M - Bromotrifluorotoluene are organic compounds. When storing and transporting, many important things need careful attention.

First, storage, because of its certain chemical activity, should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics, which are prone to danger. In case of fire, or the risk of combustion or even explosion. Storage temperature should be controlled in an appropriate range, not too high or too low, too high to increase its volatilization and reactivity, too low or crystallization affect its physical state, which is not conducive to subsequent use.

Furthermore, storage containers must be made of corrosion-resistant materials. Because of its fluoride, bromine and other elements, it has a corrosive effect on some materials. Glass or specific plastic containers are preferred, which can effectively prevent leakage and material corrosion, and ensure storage safety. And the container must be well sealed to prevent it from volatilizing into the air, not only to avoid losses, but also to prevent harm to the environment and people.

As for transportation, transportation vehicles must have good ventilation equipment to disperse possible volatile gases and reduce the risk of explosion. The loading and unloading process should be handled with care to avoid impact, fall, and prevent leakage caused by damage to the container. Transportation personnel also need to be professionally trained and familiar with the characteristics of the chemical and emergency treatment methods.

On the way, in case of leakage, the surrounding people should be evacuated immediately and the scene should be isolated. Emergency responders need professional protective equipment and do not come into direct contact with leaks. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be dammed and contained before professional treatment.

In short, when m-Bromotrifluorotoluene is stored and transported, temperature, containers, ventilation, operating specifications and emergency treatment should not be ignored, so as to keep it safe.