5 Chloro 2 Nitro Alpha Alpha Alpha Trifluorotoluene
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
5-Chloro-2-nitro-alpha,alpha,alpha-trifluorotoluene
Chemical Formula C7H2ClF3NO2
Molar Mass 225.54 g/mol
Appearance Liquid
Color Colorless to light yellow
Odor Pungent
Density 1.59 g/cm³
Boiling Point 184 - 186 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 74 °C
FAQ

What are the main uses of 5-Chloro-2-nitro-alpha, alpha, alpha-trifluorotoluene?

5-Chloro-2-nitro - α,α,α - trifluorotoluene, an organic compound, has a wide range of uses. In the field of medicine, it is often a key intermediate, helping to synthesize many specific drugs. For example, in the process of developing specific antimalarial drugs, with its unique chemical structure, it can precisely combine with specific targets of malaria parasites, effectively inhibit the growth and reproduction of malaria parasites, and provide strong support for malaria treatment.

In the pesticide industry, it is also an important synthetic raw material. After ingenious chemical reaction, it can be converted into high-efficiency insecticides. Such insecticides can precisely act on the nervous system of pests, interfere with their normal physiological activities, achieve efficient killing of pests, protect crops from insect attacks, and escort agricultural harvests.

In addition, in the field of materials science, it also shows unique value. In the synthesis of some high-end materials, the addition of this compound can significantly improve the properties of materials. For example, to enhance the corrosion resistance of materials, so that they can remain stable in harsh environments for a long time and prolong the service life of materials; to improve the heat resistance of materials, to broaden the applicable temperature range of materials, to meet the needs of more special scenarios.

Furthermore, in the field of dye synthesis, 5-chloro-2-nitro - α,α,α - trifluorotoluene plays an indispensable role. With its structural characteristics, dyes with bright colors and excellent fastness can be synthesized, which are widely used in textile printing and dyeing and other industries, bringing people a variety of fabric products.

In summary, 5-chloro-2-nitro - α,α,α - trifluorotoluene plays a key role in many fields such as medicine, pesticides, materials science and dye synthesis, and is of great significance to promote the development of various industries.

What are the physical properties of 5-Chloro-2-nitro-alpha, alpha, alpha-trifluorotoluene

5-Chloro-2-nitro - α,α,α - trifluorotoluene, this is an organic compound. Looking at its physical properties, at room temperature, it is mostly in a liquid state, with a nearly colorless to slightly yellow color, and its shape is transparent, just like a clear spring.

When it comes to smell, it exudes a special fragrance. However, this fragrance is not pleasant, and it feels pungent when smelled, just like the spicy smell collides with the sense of smell. Its density is greater than that of water. If it is placed in one place with water, it is like a stone entering water and will sink to the bottom.

Besides the boiling point, due to the structure of chlorine, nitro, trifluoromethyl and other groups, under the interaction, the boiling point is quite high, and it requires hotter energy to boil. In terms of melting point, it is relatively low, which means that it is easy to maintain a liquid state in an environment near room temperature.

Its solubility also has characteristics. In organic solvents, such as common ether and acetone, like fish get water, it is very easy to dissolve, just like salt melts in water, invisible; but in water, it is difficult to be compatible, just like oil and water, because its molecular structure is mostly caused by hydrophobic groups.

In addition, the vapor pressure of this compound is low at room temperature, that is, it evaporates relatively slowly, and it is not easy to spread rapidly in the air. Just like a calm person, it moves slowly and does not easily reveal itself. These many physical properties are its unique imprints in the world, and their application in chemical, pharmaceutical and other fields is closely related to these properties.

Are 5-Chloro-2-nitro-alpha, alpha, alpha-trifluorotoluene chemically stable?

5-Chloro-2-nitro - α,α,α - trifluorotoluene, its chemical properties are quite stable. In this compound, chlorine atoms, nitro groups and trifluoromethyl coexist. Trifluoromethyl has strong electronegativity, which can change the distribution of molecular electron clouds and affect its reactivity. However, it is connected to the benzene ring, and the conjugation system of the benzene ring confers certain stability to the molecule.

Although the chlorine atom can participate in reactions such as nucleophilic substitution, under normal conditions, the reaction is not easy to occur due to the electronic effect of the benzene ring and the influence of trifluoromethyl groups and nitro groups. The nitro group is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring, makes the electrophilic substitution reaction more difficult, but also enhances the resistance of the benzene ring to oxidation and other reactions.

Furthermore, the existence of trifluoromethyl greatly enhances the lipid solubility of the molecule, affecting its solubility and partition coefficient in different solvents. Due to the particularity of its structure, under the general environment and common chemical reaction conditions, 5-chloro-2-nitro - α,α,α - trifluorotoluene exhibits relatively stable chemical properties, and is not prone to significant chemical changes without special reagents and conditions.

What is the production process of 5-Chloro-2-nitro-alpha, alpha, alpha-trifluorotoluene?

The preparation process of 5-chloro-2-nitro - α,α,α - trifluorotoluene is particularly critical. The preparation method is often made from specific starting materials through several delicate chemical reactions.

In the past, this compound was prepared from simple aromatic hydrocarbon derivatives containing chlorine, nitro and fluorine. The first step is often a halogenation reaction, and a suitable halogenation reagent, such as a specific reagent containing chlorine, is selected. Under specific reaction conditions, such as suitable temperature, pressure and catalyst, the specific position of the aromatic derivative is precisely introduced into the chlorine atom. The key to this step is to precisely control the reaction conditions, so that the chlorine atoms fall at the target position, and avoid unnecessary side reactions, such as the formation of polyhalogenated products.

Next, the nitrogenation reaction is carried out. The nitro group is introduced into the compound with a nitrogenation reagent under the appropriate reaction medium and conditions. This process also needs to be carefully controlled, because the selectivity and degree of reaction of the nitrogenation reaction have a great influence on the purity and yield of the product. Temperature, reagent ratio, reaction time and other factors must be carefully controlled to obtain the target nitro and chlorine-containing compound.

Finally, trifluoromethyl is introduced. Special fluorine-containing reagents and reaction processes are commonly used in this step. Trifluoromethyl is successfully attached to the α position of the compound by either nucleophilic substitution reaction or free radical reaction. In this step, due to the special properties of trifluoromethyl, the reaction conditions are strict, and suitable catalysts and reaction solvents need to be selected to promote the smooth progress of the reaction and improve the selectivity and yield of the product.

Preparation of 5-chloro-2-nitro - α,α,α - trifluorotoluene requires precise control of the conditions of each step of the reaction, from the selection of raw materials, the ratio of reagents, to the reaction temperature, time and other factors, all of which are related to the quality and yield of the final product. Each step of the reaction complements each other, and the omission of any link may cause the product to be impure or the yield to be low. Therefore, the process of preparing this compound is actually a skill that requires careful study and repeated practice in the field of chemical synthesis.

What is the price range of 5-Chloro-2-nitro-alpha, alpha, alpha-trifluorotoluene in the market?

5-Chloro-2-nitro - α,α,α - trifluorotoluene, the price range in the market is difficult to determine. This is due to the complex and changeable market conditions, and the price varies with many factors.

In the past market conditions, the price of this compound often varies due to the balance between supply and demand, the price of raw materials, the simplicity and complexity of the process, and the stability of the current situation. If the supply is full, the demand is small, the price may decline; if the raw materials are rare, the process is complicated, and the current situation is turbulent, resulting in difficult transportation, the price may rise.

However, according to past experience, the price of this chemical may range from a few yuan to tens of yuan per gram. When purchasing in bulk, the price per gram may be lower due to large quantities and excellent prices; if only a small amount of purchase is required, the supplier may have a higher price per gram due to cost considerations.

In addition, the prices offered by different suppliers are also different. For merchants with a long reputation and excellent quality, their prices may be slightly higher; for new entrants to the market or those who want to expand their sales, they may attract customers at a lower price. Therefore, in order to know the exact price, it is necessary to consult various merchants and carefully observe the market conditions in order to obtain a more suitable price.