Chemical Formula | C7H5ClF3N |
Molecular Weight | 195.57 |
Appearance | Pale yellow to light brown solid |
Boiling Point | 205 - 207 °C |
Melting Point | 34 - 38 °C |
Density | 1.39 g/cm³ |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
Flash Point | 85 °C |
Purity | Typically high - purity products are around 98%+ |
What are the main uses of 4-chloro-3-aminotrifluorotoluene?
4-Cyanogen-3-aminotrifluorotoluene, which has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate for the synthesis of many drugs. Its unique structure, containing cyanide, amino and trifluoromethyl groups, gives it specific chemical activity and physical properties, and can participate in various chemical reactions to build complex drug molecular structures.
For example, in the development of anti-cancer drugs, with its special chemical properties, it can precisely act on specific targets of cancer cells and interfere with the growth, proliferation and metastasis process of cancer cells. It is also used to synthesize antibacterial drugs, showing inhibition and killing effects on common pathogens.
In the field of pesticide chemistry, it is an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. Its special structure makes the pesticide have excellent biological activity and environmental compatibility, strong contact killing, stomach toxicity and internal absorption to pests, can effectively control a variety of crop pests, and has a short residual period in the environment, which has little impact on the ecological environment.
In the field of materials science, 4-cyanogen-3-aminotrifluorotoluene can be used to prepare high-performance polymer materials. The introduction of this substance can significantly improve the thermal stability, chemical stability and mechanical properties of polymers, and the obtained materials are widely used in high-end fields such as aerospace, electronics and electrical appliances. For example, in the aerospace field, it can enhance the high temperature and corrosion resistance of aircraft parts, ensuring the stable operation of aircraft in extreme environments; in the field of electronics and electrical appliances, it is used to manufacture high-performance circuit board materials to improve the stability and reliability of electronic products.
What are the physical properties of 4-chloro-3-aminotrifluorotoluene?
4-Bromo-3-aminotrifluorotoluene is one of the organic compounds. Its physical properties are quite important, and I will describe them in detail for you.
Looking at its appearance, under normal temperature and pressure, it is mostly colorless to light yellow liquid. This color state is clearly distinguishable, and it is easy to distinguish when actually observed. It has a certain volatility and can slowly dissipate into the air in an open environment.
When it comes to boiling point, it is usually within a certain range. The characteristics of this boiling point make it possible to transform from liquid state to gas state under specific temperature conditions. Specifically, in a suitable pressure environment, its boiling point value is relatively stable. This property is very critical in chemical operations such as distillation and separation, and can be separated and purified from other substances.
Melting point is also one of the important physical properties. The melting point of 4-bromo-3-aminotoluene determines the temperature at which it converts from solid to liquid. Knowing the melting point is of great significance in the storage and transportation of substances. If the storage temperature is improper and higher than the melting point, the material form will change, or its quality and use will be affected.
In addition, the density of the compound is also specific. The density value reflects the mass of the substance contained in the unit volume. This property is indispensable in many chemical operations involving solution preparation, reaction material ratio, etc. According to the density, the required amount can be accurately measured to ensure the smooth progress of the reaction and the accuracy of the experimental results.
In terms of solubility, 4-bromo-3-aminotrifluorotoluene exhibits a certain solubility in specific organic solvents. For example, in some common organic solvents, it can be partially or completely dissolved. This property is conducive to its use as a reactant or intermediate in organic synthesis reactions, participating in various chemical reactions. Because it is dissolved in a suitable solvent, the reaction can be carried out more fully and efficiently.
What is the production method of 4-chloro-3-aminotrifluorotoluene?
To prepare 4-cyanogen-3-aminotrifluorotoluene, the following ancient method can be used.
First take the appropriate starting material, use toluene as the base, and carry out specific substitution modification. In a suitable reaction environment, add fluorine-containing reagents, so that the hydrogen atoms on the toluene benzene ring are gradually replaced by fluorine atoms to form the structure of trifluorotoluene. This process requires careful control of the reaction conditions, such as temperature, pressure, reaction time and reagent dosage, etc., to ensure that the fluorination reaction is accurate and efficient, and there are not too many side reactions.
Then, cyano and amino groups are introduced. It can be reacted with the obtained trifluorotoluene derivative with an appropriate reagent through diazotization reaction, so that the cyano group and amino group are introduced at the desired position. This step also needs to be carefully regulated to ensure that the cyano group and amino group are introduced into the check point correctly, and the target 4-cyano- 3-aminotrifluorotoluene structure is obtained.
During this period, the choice of reaction solvent is crucial. When the choice has good compatibility with the reactants and reagents, and has no adverse effect on the reaction process. The catalytic system is also indispensable. The selection of an appropriate catalyst can speed up the reaction rate and improve the reaction yield.
After each step of the reaction, it needs to be separated and purified to remove impurities and obtain a pure product. 4-Cyano-3-aminotrifluorotoluene can be obtained by distillation, extraction, recrystallization or column chromatography according to the characteristics of the product.
What are the precautions for the storage and transportation of 4-chloro-3-aminotrifluorotoluene?
4-Cyanogen-3-aminotrifluorotoluene is a special chemical substance. When storing and transporting, many things must be paid attention to to to ensure safety.
First words storage, this substance should be placed in a cool, dry and well-ventilated place. Because the substance is quite sensitive to heat and humidity, if it is exposed to high temperature or humid environment, it may cause damage to stability and cause danger. The storage place should be kept away from fire and heat sources, and all possible ignition sources should be eliminated to prevent accidental explosion. At the same time, it should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. This is because of its active chemical properties, contact with the above substances, prone to violent chemical reactions, resulting in disasters. And the storage area must be equipped with suitable materials to contain possible leaks.
As for transportation, caution is also required. Before transportation, make sure that the substance is fully packaged and tightly sealed. Packaging materials should be able to withstand certain external shocks and environmental changes to prevent leakage due to package damage during transportation. During transportation, the speed should be stable, and violent actions such as sudden braking and sharp turns should be avoided to avoid package damage due to vibration and collision. Vehicles should also be driven according to the specified route, away from sensitive areas such as densely populated areas and water sources. At the same time, transport personnel must be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. If there is a leak on the way, they can be disposed of quickly and properly.
In short, the storage and transportation of 4-cyanogen-3-aminotrifluorotoluene is a matter of safety. It should not be taken lightly at every step and every detail. It must be operated in strict accordance with regulations to ensure that nothing goes wrong.
What is the market outlook for 4-chloro-3-aminotrifluorotoluene?
In the field of 4-deuterium-3-aminotrifluoroethylbenzene, the market prospect may be promising. In today's world, the fields of medicine and materials are booming, and the demand for the two is also increasing.
In the field of Guanfu medicine, fluorine-containing and deuterated compounds have gradually become key elements in the creation of new drugs due to their special physical and biological properties. 4-deuterium-3-aminotrifluoroethylbenzene has a unique structure and may play an important role in the molecular design of drugs. It may optimize the metabolic stability of drugs, making the drug last longer in the body and have a longer-lasting effect; it may also improve the membrane permeability of drugs, helping them to penetrate biological membranes more easily and reach the target to exert their efficacy. In the field of innovative drug research and development, this compound may be an intermediate with great potential, attracting many pharmaceutical companies and scientific research institutions to compete for research, and its market demand is expected to grow gradually with the progress of new drug research and development.
As for the field of materials, fluorinated materials are known for their excellent chemical stability, thermal stability and low surface energy. The introduction of 4-deuterium-3-aminotrifluoroethylbenzene into the material structure may endow the material with different properties. For example, in high-performance polymer materials, it may improve the chemical resistance of the material and broaden the application scenarios of the material; in electronic materials, it may help improve the electrical properties of the material. With the continuous improvement of material science and technology, the demand for special performance materials is also increasing, and 4-deuterium-3-aminotrifluoroethylbenzene, as a potential functional material monomer, is also expected to usher in a broad market space.
However, although its market prospect has potential, there are also challenges. The complexity of the synthesis process or the high production cost, which is one of the major obstacles to the promotion and application. Only by unremitting research by researchers, optimizing the synthesis route and reducing costs can this compound be more competitive in the market, fully release its market potential, and expand its application territory.