3 4 5 Trifluorotoluene
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
3,4,5-Trifluorotoluene
Chemical Formula C7H4F3
Molecular Weight 146.10
Appearance Colorless liquid
Boiling Point 116 - 117 °C
Melting Point -45 °C
Density 1.239 g/cm³
Vapor Pressure 3.73 kPa at 20 °C
Flash Point 19 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Odor Characteristic odor
Refractive Index 1.406
FAQ

What are the main uses of 3,4,5-trifluorotoluene?

3,4,5-Trihydroxybenzoic acid, that is, gallic acid, its main uses are as follows:

Gallic acid is used in medicine and has considerable functions. It can be used as an antibacterial and antiviral agent to relieve various inflammatory diseases. And because of its antioxidant properties, it can block the damage of free radicals in the body, protect cells from damage, and is beneficial in delaying the aging of the body and preventing many chronic diseases, such as cardiovascular diseases and tumors.

In the food field, gallic acid can act as an antioxidant. It can inhibit the oxidative rancidity of oils and fats in food, maintain the flavor and quality of food, and extend its shelf life. It is used in many categories such as beverages, oils, baked foods, etc., so that food can be stored for a long time without deterioration.

In the chemical industry, gallic acid is also an important raw material. It can be used to make ink, because it can form a non-ferrous complex with metal ions, making the ink color stable and long-lasting. It can also be used as a tanning agent to combine with proteins in leather to increase leather's water resistance, wear resistance and anti-microbial erosion, and improve leather quality.

Furthermore, in the field of organic synthesis, gallic acid is a key intermediary. With the hydroxyl and carboxyl groups in its molecules, it can be esterified, etherified, condensed and other reactions to produce a variety of organic compounds with special properties, such as for drug synthesis, functional material preparation, etc., which are of great value in scientific research and industrial production.

What are the physical properties of 3,4,5-trifluorotoluene?

3,4,5-Tribromoacetylbenzene is one of the organic compounds. Its physical properties are very important and are related to many chemical applications.

This compound has a specific melting point. The melting point is the temperature at which a substance changes from a solid state to a liquid state. The melting point of 3,4,5-tribromoacetylbenzene can be accurately determined to know its characteristics. At a specific temperature, its solid lattice structure begins to disintegrate, and the molecules are energized to form a liquid flowing state.

Furthermore, the boiling point is also a key physical property. The boiling point is the temperature at which the saturated vapor pressure of the liquid is equal to the external pressure. When 3,4,5-tribromoacetylbenzene reaches the corresponding boiling point, a large number of molecules in the liquid can escape and form a gas phase. This boiling point value can help in separation and purification operations such as distillation, and by temperature control, it can be separated from other substances.

Solubility also needs attention. Its solubility varies in different solvents. In organic solvents such as ethanol, ether, etc., there may be different degrees of dissolution. In water, due to the polarity difference between the structure of the compound and water, the solubility may be poor. This solubility characteristic is instructive in the steps of solvent selection and product separation in organic synthesis reactions.

In addition, appearance is also one end of physical properties. 3,4,5-tribromoacetylbenzene may be in a specific color state, such as white to light yellow solid powder. This appearance characteristic can be used for visual basis in preliminary identification and quality judgment. Looking at its color state, if there are obvious abnormalities, or suggest problems with its purity.

Is the chemical properties of 3,4,5-trifluorotoluene stable?

The chemical properties of 3,4,5-trihydroxybenzoic acid are stable. This substance has the properties of phenolic hydroxyl group and carboxyl group, phenolic hydroxyl group, easy to oxidize, and gradually changes color in the air. However, in its structure, the resistance of hydroxyl group and carboxyl group and electronic effect make it slightly more stable. The carboxyl group is acidic and can form a salt with a base. This reaction is easier, but due to the influence of ortho-hydroxyl group, its acidity is slightly different from that of ordinary benzoic acid.

In terms of stability, the conjugated system of the benzene ring gives it a certain stability. However, the phenolic hydroxyl group is active and easy to be attacked by oxidants, causing structural changes. In case of strong oxidants, phenolic hydroxyl group or quinone structure. However, in the presence of normal and no oxidants, its stability is acceptable in dry and cool places.

And due to the intramolecular hydrogen bonds, its melting and boiling point may be different from common sense. Hydroxy and carboxyl groups can form intramolecular hydrogen bonds, which affect the intermolecular forces and then affect their physical state changes. This hydrogen bond also stabilizes its structure to a certain extent, so that the molecular configuration is relatively fixed and not easily deformed.

In summary, the stability of 3,4,5-trihydroxybenzoic acid has two sides. The benzene ring and the intramolecular hydrogen bond help it to stabilize, and the activity of phenolic hydroxyl groups is the source of instability. Under proper preservation and avoidance of oxidants, it can be stable for a certain period of time.

What is the preparation method of 3,4,5-trifluorotoluene?

For 3,4,5-tribromoethylbenzene, the method of preparation is as follows:

First take ethylbenzene as the starting material, place it in an appropriate vessel, and introduce bromine with iron filings or iron tribromide as the catalyst. This is because the hydrogen atom on the benzene ring of ethylbenzene can be replaced by the bromine atom. The benzene ring of ethylbenzene is affected by the ethyl group, and the hydrogen atom activity of the ortho and para-position is slightly increased. When bromine meets ethylbenzene under the action of the catalyst, the bromine molecule is polarized, and the positively charged bromine atom first interacts with the π electron cloud of the benzene ring to form an unstable intermediate. Subsequently, the intermediate loses a proton, forming a mixture of o-bromoethylbenzene and p-bro < Br >
However, if you want to obtain 3,4,5-tribromoethylbenzene, you need to control the reaction conditions. Increasing the temperature and the amount of bromine prompts more bromine atoms to replace the hydrogen atoms on the benzene ring. Due to the increase in temperature, the reactivity increases, and bromine atoms are more likely to attack hydrogen at different positions on the benzene ring. And increasing the amount of bromine can make the reaction more complete, and gradually introduce multiple bromine atoms into the benzene ring.

After the reaction is completed, the mixture contains a variety of bromoethylbenzene products. At this time, 3,4,5-tribromoethylbenzene is separated and purified from the mixture by distillation, extraction, recrystallization, etc. The method of distillation can be divided into gasification and condensation according to the different boiling points of each bromoethylbenzene; extraction uses the different solubility of different bromoethylbenzene in different solvents to extract the target product; recrystallization is to borrow 3,4,5-tribromoethylbenzene The solubility of tribromoethylbenzene in a specific solvent changes with temperature, and then dissolves, cools, crystallizes and other steps to obtain a pure product. After these operations, 3,4,5-tribromoethylbenzene can be obtained.

What are the precautions for storing and transporting 3,4,5-trifluorotoluene?

When storing and transporting 3,4,5-trifluoroacetaniline, many matters need to be paid attention to.

When storing, the temperature and humidity of the environment are the first priority. The nature of this substance may be affected by changes in temperature and humidity. It should be placed in a cool and dry place to prevent it from being damp and deteriorated due to excessive humidity, or causing chemical reactions due to excessive temperature, which will damage the quality. In the warehouse, the temperature should be controlled within a specific range, and the humidity should also be maintained stable.

Furthermore, it is necessary to prevent it from mixing with other chemicals. 3,4,5-trifluoroacetaniline may react chemically with certain substances, such as oxidizing and reducing substances, so it should be placed separately from such chemicals to avoid interaction and ensure safety.

In addition, the packaging must be tight. The packaging material should have good sealing and corrosion resistance to prevent material leakage. Damage to the packaging can easily cause material loss, pollute the environment, and cause safety accidents.

During transportation, the same cannot be slack. The transportation vehicle needs to be clean and dry to ensure that there are no residual substances that may react with it. When loading, pay attention to light loading and light unloading to avoid damage to the packaging due to collisions and falls.

During transportation, strictly control the transportation conditions. If it is a long-distance transportation, it is necessary to regularly check the packaging condition and environmental factors such as temperature and humidity. In case of bad weather, such as heavy rain, high temperature, etc., corresponding protective measures need to be taken, such as covering the rain cloth, controlling the temperature of the carriage, etc., to ensure the stability and safety of 3,4,5-trifluoroacetaniline during transportation. In this way, 3,4,5-trifluoroacetaniline can be properly stored and transported to avoid various risks.