What is the chemical structure of (Z) 2- (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridin-3-yl) -5- (phenyldiazenyl) pyrimidine-4,6-diamine

The name of this substance is (Z) -2 - (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridine-3-yl) -5- (phenylhydrazinyl) pyrimidine-4,6-diamine. To clarify its chemical structure, its name needs to be analyzed. " Pyrimidine-4,6-diamine "shows that the structure is based on the pyrimidine ring and has an amino group at the 4,6 position;" 5- (phenylhydrazinyl) "shows that the pyrimidine ring is connected with a phenylhydrazinyl group at the 5 position;" 2- (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridino-3-yl) "means that the pyrimidine ring is connected with 1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridino-3-yl at the 2 position. In the 1 - (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridine-3-group, the pyrazolo [3,4-b] pyridine ring is connected to 2-fluorobenzyl at position 1, and the pyrimidine ring at position 3 is connected to position 2. Thus, the chemical structure of this complex compound gradually becomes clear.

What are the physical properties of (Z) 2- (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridin-3-yl) -5- (phenyldiazenyl) pyrimidine-4,6-diamine

(Z) -2 - (1 - (2 - fluorobenzyl) -1H - pyrazolo [3,4 - b] pyridine - 3 - yl) - 5 - (phenylhydrazinyl) pyrimidine - 4,6 - diamine The physical properties of this substance are as follows:

In terms of view, it is mostly in a crystalline solid state, and it has good stability under conventional environments. Its melting point is about a specific temperature range, which is one of the important characteristics for identifying this substance. Due to the rich nitrogen, fluorine and other elements in the molecular structure, it has a certain polarity and has different solubility in common organic solvents. In polar organic solvents such as dimethyl sulfoxide, N, N-dimethylformamide, it exhibits good solubility and can be rapidly dispersed and dissolved; in non-polar organic solvents such as n-hexane and toluene, the solubility is very small, and only a very small amount of solubility is seen.

In addition, because the molecular structure contains a conjugated system, this substance may be absorbed at a specific wavelength of light, and this characteristic can be used to measure it qualitatively and quantitatively by means of spectral analysis. And its intermolecular interactions such as hydrogen bonds and van der Waals forces also affect its physical properties, such as melting point and boiling point, which are closely related to such interactions.

What is the synthesis method of (Z) 2- (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridin-3-yl) -5- (phenyldiazenyl) pyrimidine-4,6-diamine

The synthesis of (Z) -2- (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridine-3-yl) -5- (phenylhydrazinylpyrimidine) -4,6-diamine is a challenging issue in organic synthesis.

To form this compound, the choice of starting materials is crucial. Pyrazolo-pyridine derivatives containing specific substituents can be obtained by nucleophilic substitution reaction with intermediates containing 2-fluorobenzyl halides and pyrazolo [3,4-b] pyridine structures. In this step, suitable bases and solvents need to be selected to promote the reaction. Alkalis, such as potassium carbonate, sodium carbonate, etc., can help the halide to leave; solvents depend on the characteristics of reactants, such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO) and other polar aprotic solvents are preferred, because they are soluble in reactants and facilitate the reaction.

As for the construction of pyrimidine-4,6-diamine parts, or the introduction of amino groups by the corresponding pyrimidine derivatives through aminolysis reaction. In this process, temperature, reaction time and the proportion of reactants are all key variables. If the temperature is too high or side reactions multiply, if it is too low, the reaction will be delayed; an appropriate ratio of reactants can improve the yield of the target product. < Br >
The introduction of the key 5- (phenylhydrazinyl) part can be achieved by the coupling reaction of diazonium salts and pyrimidine derivatives. The preparation of diazonium salts requires careful operation, often obtained by the diazotization of aniline compounds. The reaction conditions need to be precisely regulated, and pH value and temperature will affect the stability and reactivity of diazonium salts. When coupling with pyrimidine derivatives, the selection of suitable catalysts and additives can improve the reaction efficiency and selectivity.

After each step of the reaction, the separation and purification of the product cannot be ignored. It can be purified by column chromatography, recrystallization and other methods according to the characteristics of the product to obtain high purity (Z) -2- (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridine-3-yl) -5- (phenylhydrazinyl) pyrimidine-4,6-diamine.

What are the application fields of (Z) 2- (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridin-3-yl) -5- (phenyldiazenyl) pyrimidine-4,6-diamine

(Z) -2 - (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridine-3-yl) -5- (phenylhydrazinyl) pyrimidine-4,6-diamine, this compound may have many applications in the field of pharmaceutical chemistry.

The structure of this compound is complex and exquisite, and it may have unique efficacy in the process of drug research and development. In the field of anti-tumor, it may be able to precisely combine with specific targets of tumor cells with its unique chemical structure, interfering with key processes such as tumor cell proliferation and invasion, just like the magic weapons of ancient times, hitting the key points and curbing the raging trend of tumors.

In the field of anti-inflammatory immune regulation, it may also play a role. Its structural characteristics may regulate the activity of immune cells and correct immune imbalance, just like the sage regulating the court, so that the body's immune order returns to stability and relieves inflammation.

In the exploration of drugs for neurological diseases, the structure of this compound may cross the blood-brain barrier, interact with nerve cell receptors or related proteins, improve neurotransmitter transmission, such as a good doctor's hand, repair the dysfunction of the nervous system, and bring new opportunities for the treatment of related diseases.

From the perspective of (Z) -2 - (1 - (2 - fluorobenzyl) -1H - pyrazolo [3,4 - b] pyridine - 3 - yl) - 5 - (phenylhydrazinyl) pyrimidine - 4,6 - diamine has potential application value in many fields of medicine, and is expected to create a new situation for human health and well-being.

What is the market outlook for (Z) 2- (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridin-3-yl) -5- (phenyldiazenyl) pyrimidine-4,6-diamine?

(Z) -2 - (1- (2-fluorobenzyl) -1H-pyrazolo [3,4-b] pyridine-3-yl) -5- (phenylhydrazinyl) pyrimidine-4,6-diamine. The market prospect of this compound is really related to many parties.

Looking at the field of its pharmaceutical research and development, it may have unique potential. The structure of this compound fuses several specific groups, and it may have specific effects on drug targets. If it can accurately fit some disease-related targets, such as those of key pathways such as tumors and inflammation, it is expected to be developed into new specific drugs. However, the road to the development of new drugs is full of thorns. Rigorous pharmacological experiments are required to investigate its efficacy, safety and toxic side effects in detail. Although the prospect is attractive, the road to becoming a drug requires crossing many barriers and investing huge amounts of manpower, material resources and time.

In the chemical industry, or can be used as a synthetic intermediate for new materials. Its unique structure can introduce special properties to new materials, such as optimizing the optical, electrical or mechanical properties of materials. However, chemical applications also face challenges, and optimization of synthesis processes and cost control are key. If the synthesis process is complicated and costly, it may be difficult to apply it to chemical production on a large scale.

At the level of market competition, similar structural compounds may already exist in the market. To stand out, you need to demonstrate unique advantages, such as better performance, lower cost or easier access. And marketing activities cannot be ignored, and need to be recognized by the industry and favored by customers.

In summary, (Z) -2 - (1- (2-fluorobenzyl) -1H-pyrazolo [3,4 - b] pyridine-3-yl) -5- (phenylhydrazinyl) pyrimidine-4,6 - diamine market prospects, opportunities and challenges coexist. Only through unremitting research and development, process optimization and effective market strategies can we have the opportunity to occupy a place in the market.