What is the chemical structure of ethyl 5 - amino - 1 - (2 - fluorobenzyl) -1H - pyrazole - 3 - carboxylate

"Ethyl + 5 - amino - 1 - (2 - fluorobenzyl) -1H - pyrazole - 3 - carboxylate", which is the English name of organic compounds. According to the naming rules of organic chemistry, its chemical structure can be analyzed.

"Ethyl", ethyl is also an alkyl group containing two carbon atoms, often expressed as "-C ² H". "5 - amino", which means that there is an amino group (-NH ²) substituted at the fifth position. " 1 - (2 - fluorobenzyl) "refers to the number one position connected with 2-fluorobenzyl, and the second position of the benzene ring of 2-fluorobenzyl is obtained by the substitution of the fluorine atom (F)." 1H-pyrazole ", that is, the pyrazole ring, is a five-membered heterocycle containing two adjacent nitrogen atoms, and one of the nitrogen atoms is in the No. 1 position." 3-carboxylate "indicates that there is a carboxylate group (-COOR) in the third position, and this" R "can be known as ethyl (-C ² H) at" ethyl ".

In summary, the chemical structure of this compound is a pyrazole ring as the core, the first position is connected to 2-fluorobenzyl, the third position is connected to carboxylate ethyl, and the fifth position has amino substitution. Its structure is roughly like this, and it is a compound with a specific structure in organic synthesis and chemical research.

What are the physical properties of ethyl 5 - amino - 1 - (2 - fluorobenzyl) -1H - pyrazole - 3 - carboxylate

Ethyl-5-amino-1- (2-fluorobenzyl) -1H-pyrazole-3-carboxylic acid ester, this material property is slightly different from the usual class. Its shape is either crystalline, pure in color, or white like frost or snow, or with a faint glow, shining in the sun. Its melting degree is quite fixed, and when heated to a certain temperature, it begins to melt, just like ice when warm.

As for its solubility, it varies in various solvents. When it comes to alcohols, it may gradually dissolve, such as salt entering soup, quietly melting, and the solution is clear; when it comes to water, it is slightly soluble. If duckweed is in a lake, only a small part is mixed with water. Its density also has characteristics, slightly heavier than water, and it is thrown into the vessel and sinks to the bottom of the water, just like a stone falling into the abyss pool.

And the stability of this thing is still good. In ordinary temperature and humidity, it can be left for a long time without changing its properties. However, in case of strong acid and alkali, it is like a warrior who is on the verge of battle, causing violent changes, its structure is broken, and its physical properties are also changed. And under the light, although the change does not appear in a moment, it lasts a little longer, and there are gradually abnormal changes, or color changes, or qualitative changes, which cannot be ignored.

What are the synthetic methods of ethyl 5 - amino - 1 - (2 - fluorobenzyl) -1H - pyrazole - 3 - carboxylate

There are various ways to synthesize ethyl 5 - amino - 1 - (2 - fluorobenzyl) -1H - pyrazole - 3 - carboxylate.

First, it can be obtained from suitable starting materials through multi-step reaction. First, take a fluorobenzyl halide and a pyrazole-containing ring precursor, in the presence of a base, undergo a nucleophilic substitution reaction. For bases, such as potassium carbonate and sodium carbonate, in a suitable organic solvent, such as acetonitrile, N, N - dimethylformamide (DMF), heat and reflux to connect the two to form a fluorobenzyl-substituted pyrazole intermediate.

Then, the intermediate needs to be aminated and carboxyl esterified at a specific position on the pyrazole ring. For the aminization step, suitable aminization reagents, such as ammonia gas and amine compounds, can be selected to react under specific conditions. Carboxyl esterification, the corresponding carboxylic acid can be combined with ethanol under acid catalysis, such as concentrated sulfuric acid, or by coupling reagents, such as dicyclohexyl carbodiimide (DCC) and 4-dimethylaminopyridine (DMAP) system, esterification reaction occurs, and the final product is ethyl 5-amino-1 - (2-fluorobenzyl) -1H-pyrazole-3-carboxylate.

Second, it can also be started from another angle. The pyrazole ring structure is constructed first, and the carboxyl functional group is introduced at the same time, and then benzylation and aminylation are carried out. Starting with carboxyl-containing pyrazole derivatives, benzylation is carried out by reacting with 2-fluorobenzyl halides. Then the carboxyl group is converted into ethyl ester group by appropriate methods, such as reacting with ethanol under a specific catalytic system. Finally, specific aminylation methods, such as reacting with a suitable amino source, are used to complete the synthesis of the target compound. These methods have their own advantages and disadvantages. According to the actual situation, factors such as the availability of raw materials, the difficulty of reaction conditions, and the high and low yield need to be considered in order to choose the best synthesis path.

What is the main use of ethyl 5 - amino - 1 - (2 - fluorobenzyl) -1H - pyrazole - 3 - carboxylate

Ethyl-5-amino-1- (2-fluorobenzyl) -1H-pyrazole-3-carboxylic acid ester, this is an organic compound. It has a wide range of uses in the field of medicinal chemistry and is often used as a key intermediate to help create new drugs. Due to the diverse biological activities of pyrazole compounds, such as anti-inflammatory, antibacterial, and anti-tumor, this compound may play an important role in the development of corresponding functional drugs.

In the field of pesticide chemistry, this substance also has potential uses. Pyrazole structure exists in some pesticide components, which can endow pesticides with insecticidal, bactericidal, herbicidal and other properties. Ethyl-5-amino-1- (2-fluorobenzyl) -1H-pyrazole-3-carboxylate may become the basic raw material for the development of new and efficient pesticides.

Furthermore, in the field of organic synthesis, due to its specific structure, it can be used as the cornerstone for the construction of more complex organic molecules. Through various chemical reactions, many compounds with unique structures and properties can be derived, providing material support for the development of materials science and other related fields.

Ethyl 5 - amino - 1 - (2 - fluorobenzyl) -1H - pyrazole - 3 - carboxylate

Today there is ethyl + 5 - amino - 1 - (2 - fluorobenzyl) -1H - pyrazole - 3 - carboxylate, and its market prospect is related to many aspects. This substance may have unique potential in the field of pharmaceutical research and development. Looking at the development of medicine in the past, new compounds have often been the cornerstone of the birth of innovative drugs. If this compound can demonstrate specific biological activities, such as the effect on certain disease-related targets, or can become an opportunity for new drug development, it will emerge in the market.

In the field of pesticides, it also has potential. Today there is an increasing demand for highly efficient, low-toxic and environmentally friendly pesticides. If this compound is confirmed to have significant inhibition or killing effects on pests by research, and has a small impact on the environment, it is expected to gain a place in the pesticide market and meet the needs of agricultural production.

However, its market prospects also pose challenges. The complexity of the synthesis process will affect the production cost. If the synthesis steps are cumbersome and the raw materials are expensive, large-scale production and marketing activities will be limited. And the market competition is fierce, and it needs to compete with similar or potential replacement products. Only with excellent performance and reasonable cost can we win the favor of the market. Overall, ethyl + 5 - amino - 1 - (2 - fluorobenzyl) -1H - pyrazole - 3 - carboxylate has potential opportunities, but it needs to be further studied and optimized to clarify its exact position and prospects in the market.