What is the chemical structure of ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridin-3-yl} carbamate (2Z) -butt-2-enedioate

Ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridin-3-yl} carbamate (2Z) -but-2-enedioate, this is the English name of an organic compound. According to the nomenclature of organic chemistry, its chemical structure can be analyzed as follows:

The main body of the compound is composed of three parts. One is a pyridine ring, which is connected with an amino group at the 2nd position, and the 6th position is connected with 4-fluorobenzyl through an imino group. Second, the 3-position of the pyridine ring is partially connected to the carbamate, which refers to carbamate, that is, the ester group formed by the carbamyl group and ethanol. Third, (2Z) -but - 2 - enedioate is fumarate, indicating that the compound exists in the form of a salt of fumaric acid, which is composed of ethyl carbamate derivatives containing pyridine structure and fumaric acid.

In this compound structure, the pyridine ring acts as the core skeleton, giving it a specific electron cloud distribution and chemical activity. The presence of amino groups can provide basic check points and participate in various nucleophilic reactions. The introduction of 4-fluorobenzyl not only increases the hydrophobicity of the molecule, but also affects the electronic effect of the whole molecule due to the electronegativity of the fluorine atom. The urethane part contains not only the functional group of carbamoyl group with potential reactivity, but also a certain steric resistance and chemical stability brought by the ethyl ester group. As a counterion, fumarate, as a counterion, binds to the cationic part containing the pyridine structure through ionic bonding, which may play an important role in regulating the solubility, stability and biological activity of the compound.

What is the main use of ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridin-3-yl} carbamate (2Z) -butt-2-enedioate

Ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridine-3-yl} carbamate (2Z) -butyl-2-enediate, an organic compound. It has a wide range of uses and is often used as an intermediate in drug development in the field of medicine. Due to its specific chemical structure, it can participate in many key chemical reactions, help to construct molecular structures with specific biological activities, and lay the foundation for the creation of new drugs.

In the field of organic synthesis, this compound is also an important building block. Chemists can modify and modify their structures to derive a series of compounds with similar structures but different functions, expand the types and functions of organic compounds, and meet the needs of compounds with special properties in different fields.

In the field of materials science, after specific treatment and processing, materials may be endowed with some unique properties, such as specific optical and electrical properties, which are expected to be applied to the development of new functional materials and promote the progress and innovation of materials science.

In conclusion, ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridine-3-yl} carbamate (2Z) -butyl-2-enediate has important potential value in many scientific research and industrial production fields, providing a key material basis and research direction for the development of related fields.

What is the safety of ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridin-3-yl} carbamate (2Z) -butt-2-enedioate

V ethyl {2 - amino - 6 - [ (4 - fluorobenzyl) amino] pyridin - 3 - yl} carbamate (2Z) - but - 2 - enedioate is a chemical substance. However, in order to clarify its safety, it is necessary to study from multiple ends.

Looking at the chemical structure, this compound contains specific functional groups. Amino, fluorobenzyl amino, pyridyl and carbamate ethyl parts have their own properties. Its structure may affect its own stability and reactivity. If the structure is unstable, under specific environments, or biodegradation and transformation, the safety of the product is unpredictable.

Re-discussion of its toxicity. If there is a lack of previous studies, it is difficult to determine its effect on organisms. Oral, percutaneous or inhalation, or cause different effects. In the absence of animal experiments, it is difficult to predict its toxicology to the human body, such as whether it damages organs, disturbs metabolism, and is unknown.

Environmental safety is also an important item. If this substance is released into the environment, how degradable is it? Can it be decomposed by microorganisms, or persistent residue? And the state of migration and transformation between environmental media is related to the ecosystem. If it accumulates in organisms, it is transmitted through the food chain, or harms high-level organisms.

The synthesis process is also related to safety. The toxicity of the raw materials and reagents used, and the severity of the reaction conditions all affect the safety of the final product. If highly toxic raw materials are used in synthesis and not removed, the risk will increase.

In summary, the safety of ethyl {2-amino-6 - [ (4-fluorobenzyl) amino] pyridin-3 - yl} carbamate (2Z) - but - 2 - enedioate has not been determined in many aspects due to the lack of research. It is still necessary to explore in depth to clarify its biological and environmental impact.

What are the synthesis methods of ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridin-3-yl} carbamate (2Z) -butt-2-enedioate

The synthesis of ethyl {2 - amino - 6 - [ (4 - fluorobenzyl) amino] pyridin - 3 - yl} carbamate (2Z) - but - 2 - enedioate is particularly complicated and requires multiple and delicate reactions.

The first step is often to use a suitable pyridine derivative as the starting material. This pyridine derivative needs to have a modifiable check point to introduce the desired substituent. Under appropriate reaction conditions, a nucleophilic substitution reaction is used to react with fluorobenzyl amines at specific positions on the pyridine ring. In this step, the reaction temperature, reaction time and the ratio of the reactants need to be precisely adjusted, so that the benzylamine can be successfully connected to the 6-position of the pyridine ring to generate 6- [ (4-fluorobenzyl) amino] pyridine derivatives.

The second step is to modify the 2-position of the pyridine ring. The introduction of the 2-position amino group in a specific reaction environment is achieved by suitable amination reagents. This process requires consideration of the type and amount of reaction solvent and base to ensure that the amination reaction is carried out efficiently and selectively to obtain 2-amino-6- [ (4-fluorobenzyl) amino] pyridine intermediates. < Br >
Then, the resulting intermediate is reacted with ethyl carbonate reagents to form the carbamate structure. This reaction needs to be carried out under specific temperature and pressure conditions in the presence of a suitable catalyst to promote the smooth binding of the pyridine ring 3 to ethyl carbonate to form ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridin-3-yl} carbamate.

Finally, ethyl {2 - amino - 6 - [ (4 - fluorobenzyl) amino] pyridin - 3 - yl} carbamate is reacted with (2Z) - but - 2 - enedioic acid (or its active derivative). Under mild reaction conditions, ethyl {2 - amino - 6 - [ (4 - fluorobenzyl) amino] pyridin - 3 - yl} carbamate (2Z) - but - 2 - enedioate is formed by salt formation. After each step of the reaction, delicate separation and purification operations, such as column chromatography and recrystallization, are required to ensure the purity of the product and provide high-quality raw materials for subsequent reactions, so that the target product can be successfully synthesized.

Ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridin-3-yl} carbamate (2Z) -but-2-enedioate What are the relevant market information?

Wen Jun inquired about the relevant market information of "ethyl {2-amino-6- [ (4-fluorobenzyl) amino] pyridin-3-yl} carbamate (2Z) -but-2-enedioate", which is a specific chemical substance. However, it is difficult to find detailed market information in the classics.

Or because the substance is a newly developed product and has not been widely circulated in the market, it is rarely recorded. Or its use is relatively niche, limited to specific fields such as chemical industry and pharmaceutical research and development, so it is not highlighted in the business classics that are well known to the public.

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