Chemical Formula | C14H11F2N3 |
Molar Mass | 259.257 g/mol |
Appearance | Solid (usually white or off - white) |
Physical State At Room Temp | Solid |
Melting Point | Data may vary, specific value depends on purity |
Boiling Point | Data may vary, specific value depends on purity |
Solubility In Water | Low solubility |
Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane, ethanol to some extent |
Pka | Data may vary, related to its acidic or basic nature in solution |
Logp | Value indicates lipophilicity, data may vary |
Chemical Formula | C14H11F2N3 |
Molar Mass | 259.257 g/mol |
Appearance | Solid (usually) |
Melting Point | Specific value would require literature search |
Boiling Point | Specific value would require literature search |
Solubility In Water | Low (organic compound, likely hydrophobic) |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
Density | Specific value would require literature search |
Pka | Specific value would require literature search |
Stability | Stable under normal conditions, but may react with strong oxidizing or reducing agents |
What is the main use of 5- (3,5-difluorobenzyl) -1H-indazole-3-amine?
5- (3,5-diethylamino) -1H-indole-3-formaldehyde, which is widely used in the field of medicinal chemistry.
In the process of drug development, it is often a key intermediate. Due to its specific chemical structure, it can interact with many targets in organisms, assisting chemists in creating new therapeutic drugs. For example, in the exploration of anti-tumor drugs, it may participate in the construction of molecular structures with unique activities, which combine with specific proteins and enzymes of tumor cells to interfere with the growth and proliferation of tumor cells, contributing to the solution of cancer problems.
In the development of neurological drugs, it is also of great significance. Or it can be modified by the structure to regulate the release and uptake of neurotransmitters and improve the neurotransmission function. It is expected to become a potential lead compound for the treatment of neurological diseases such as Alzheimer's disease and Parkinson's disease, and bring good news to patients suffering from such diseases.
In the field of materials science, it has also made its mark. Due to its unique optical and electrical properties, it may be applied to the creation of organic optoelectronic materials. For example, through rational design and other materials, excellent organic Light Emitting Diode (OLED) materials can be prepared, providing the possibility for display technology innovation, making the screen display clearer and more colorful.
In addition, in the field of dye chemistry, 5- (3,5-diethylamino) -1H-indole-3-formaldehyde may exhibit unique color and light stability due to its special structure, which can be used to develop new dyes to meet the needs of high-quality, environmentally friendly dyes in textile, printing and other industries.
What are the synthesis methods of 5- (3,5-difluorobenzyl) -1H-indazole-3-amine?
To prepare 5- (3,5-difluorobenzyl) -1H-indole-3-formaldehyde, there are many methods. First, we can start from the raw material and borrow the method of nucleophilic substitution. First, we take suitable halogenated hydrocarbons and compounds containing indole structures. Under suitable reaction conditions, such as specific solvents, temperatures and catalysts, the halogen atoms are replaced and the benzyl group is connected. Then, the specific group is converted into an aldehyde group through a specific oxidation step. This process requires fine regulation of the reaction conditions to preserve yield and purity.
Second, the cyclization reaction strategy can also be used. The indole ring is formed by cyclization with a chain-like compound with suitable functional groups as the starting material. During the cyclization process, difluorobenzyl-containing structural units are ingeniously introduced. After the indole ring is formed, a specific position is modified, and the target aldehyde group is generated by suitable oxidation means. The key to this path lies in the efficient progress of the cyclization reaction and the precise control of subsequent modification steps.
Third, the method of metal catalysis can also be considered. With the help of the unique activity and selectivity of metal catalysts, the formation and transformation of specific chemical bonds can be achieved. For example, a specific metal complex is used as a catalyst to catalyze the coupling reaction between substrates to build the basic skeleton of the target molecule. After further functional group conversion, 5- (3,5-difluorobenzyl) -1H-indole-3-formaldehyde was obtained. This method has high requirements for the selection of metal catalysts and the optimization of the reaction system, but its selectivity and efficiency may be advantageous.
What is the market outlook for 5- (3,5-difluorobenzyl) -1H-indazole-3-amine?
5- (3,5-diethylamino) -1H-indole-3-formaldehyde, which is worth exploring in the current market prospect.
In the field of Guanfu medicine, such compounds are often key active ingredients of traditional Chinese medicine or intermediates in the synthesis of western medicine. Its unique structure can be chemically modified to obtain new compounds with unique pharmacological activities in the process of drug development, and then applied to many fields such as anti-tumor, anti-virus, neurological disease treatment, etc. In terms of anti-tumor, it may be able to use specific mechanisms, such as interfering with the signaling pathway of tumor cells, or inducing apoptosis of tumor cells, to open up new avenues for the creation of anti-cancer drugs, so the pharmaceutical market has a promising future.
In the field of materials, 5- (3,5-diethylamino) -1H-indole-3-formaldehyde may emerge in the field of organic optoelectronic materials due to its own electronic structure and optical properties. Such as being used as a luminescent material for organic Light Emitting Diodes (OLEDs), or showing excellent luminescence properties due to special molecular structures, improving the resolution and color saturation of OLED displays, and meeting the increasing demand for display technology in electronic devices, it is also expected to open up a world in this field.
Of course, the market expansion of this compound also faces challenges. The synthesis process may have high complexity and high cost. If large-scale industrial production is to be carried out, it is urgent to reduce costs and optimize the process. And the market competition is fierce. In order to win a place in the fields of medicine and materials, it is necessary to continuously improve technology and improve product quality and performance.
Overall, although 5- (3,5-diethylamino) -1H-indole-3-formaldehyde has considerable market potential, it is still necessary to overcome many difficulties in order to fully explore it. With time and reasonable planning, it may be able to bloom in the relevant market.
What are the physicochemical properties of 5- (3,5-difluorobenzyl) -1H-indazole-3-amine?
5- (3,5-diethylamino) -1H-indole-3-formaldehyde, this is an organic compound. Its physical and chemical properties are quite important, and it is related to the application of this compound in many fields.
In terms of physical properties, under normal conditions, 5- (3,5-diethylamino) -1H-indole-3-formaldehyde is mostly solid and has a specific melting point. Due to the specific groups in the molecular structure, its melting point is affected by factors such as intermolecular forces. The color state of this compound is usually white to light yellow powder or crystal, which is helpful for preliminary identification in experiments and production.
In terms of solubility, its molecular structure contains polar and non-polar parts, so it has unique solubility in organic solvents. In common organic solvents such as ethanol and chloroform, it has a certain solubility, because the molecules and solvents can form suitable interactions, such as van der Waals force, hydrogen bond, etc. However, in water, its solubility is relatively low, because water is a strong polar solvent, and the intermolecular force with this compound is weak.
In terms of chemical properties, the aldehyde group of 5- (3,5-diethylamino) -1H-indole-3-formaldehyde is extremely active. The aldehyde group can participate in many chemical reactions, such as oxidation reaction, which can be oxidized to the corresponding carboxylic acid; it can also undergo reduction reaction to form alcohol compounds. In addition, the diethylamino part of the molecule where the nitrogen atom is located, because the nitrogen atom has a lone pair of electrons, shows a certain alkalinity, and can react with acids to form salt compounds. These chemical properties make 5- (3,5-diethylamino) -1H-indole-3-formaldehyde an important raw material in the field of organic synthesis, which can be used to construct more complex organic molecular structures.
What are the applications of 5- (3,5-difluorobenzyl) -1H-indazole-3-amine in the field of medicine?
5- (3,5-diethylamino) -1H-indole-3-formaldehyde, this compound has many wonderful uses in the field of medicine.
It can be used to create antidepressant drugs. Because modern people suffer from depression, the properties of this compound can act on the human neurotransmitter system, regulate the levels of key transmitters such as serotonin and dopamine, just like it can correct the disordered strings, return neural signaling to harmony and order, and help patients relieve the haze of depression and regain a happy mood.
It has also made a name for itself in the development of anti-tumor drugs. The raging of tumors is very harmful. This compound is like a heroic defender, which can inhibit the proliferation of tumor cells, induce their apoptosis, and curb the growth and spread of tumors. It is like a precise sharp blade, piercing directly at the heart of tumor cells, breaking the crazy division of tumor cells, and adding a powerful weapon to the fight against tumor diseases.
It has also attracted much attention in the treatment of neurological diseases. Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease seriously affect patients' life and cognitive ability. This compound can pass through the blood-brain barrier and reach the interior of the nervous system like a messenger, exert the effect of neural protection, repair damaged nerve cells, maintain the normal function of nerve cells, delay the process of nervous system diseases, and bring new hope to patients.