Chemical Formula | C8H6F4O2 |
Molar Mass | 210.125 g/mol |
Appearance | Typically a colorless to light - colored liquid or solid |
Boiling Point | Data may vary, estimated around 190 - 210 °C (approximate range) |
Density | Data may vary, typically in the range of 1.4 - 1.6 g/cm³ (approximate) |
Solubility In Water | Low solubility in water due to its non - polar fluorinated and benzyl - like structure |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone, dichloromethane |
Vapor Pressure | Low vapor pressure at room temperature |
Refractive Index | Data may vary, around 1.45 - 1.48 (approximate) |
Chemical Formula | C8H6F4O2 |
Molecular Weight | 210.126 |
Solubility In Water | Low solubility (organic nature) |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, dichloromethane |
Vapor Pressure | Low vapor pressure (estimated based on molecular structure) |
Stability | Stable under normal conditions, but reactive with strong oxidizing agents |
What is the main use of 4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol?
4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol, which has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of specific drugs. Due to its unique chemical structure, it endows the prepared drugs with specific pharmacological activities and characteristics, such as enhancing the affinity of the drug to specific targets, improving the efficacy, or optimizing the pharmacokinetic properties, improving its absorption, distribution, metabolism and excretion in the body, making the drug safer and more effective.
In the field of pesticides, 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol also plays an important role. It can be used as a raw material for the synthesis of new pesticide active ingredients. The prepared pesticides have a high-efficiency control effect on pests, and have a small impact on the environment, which is in line with the current green and environmentally friendly agricultural development needs. Its special structure may give pesticides a unique mechanism of action to avoid pest resistance and prolong the service life of pesticides.
In the field of materials science, 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol can participate in the synthesis of functional materials. With its fluorine-containing and methoxy-group characteristics, it may endow materials with special properties, such as improving material weather resistance, chemical stability and electrical properties. In electronic materials, it may improve material insulation properties and stability; in polymer materials, it may optimize material surface properties and mechanical properties.
In conclusion, 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol, with its unique chemical structure, plays an important role in many fields such as medicine, pesticides and materials science, providing key support for innovation and development in various fields.
What are the physical properties of 4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol
4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol, is a kind of organic compound. Its physical properties are quite unique, let me tell you one by one.
Looking at its appearance, under normal temperature and pressure, it is usually a colorless to light yellow liquid, with a pure and transparent texture, like jade dew. Its smell is also unique, emitting a slight and specific aroma. Although it is not strong and pungent, it can be inadvertently detected by the sense of smell.
When it comes to the melting point, the melting point is about a relatively low range, so that when the ambient temperature is slightly higher, it is very easy to change from solid to liquid. The boiling point is relatively moderate, and under specific pressure conditions, it will boil and vaporize in a certain temperature range. This melting-boiling point characteristic is closely related to the intermolecular forces and structures. In its molecular structure, the presence of methoxy and tetrafluoride atoms affects the intermolecular forces, thus shaping this melting-boiling point characteristic.
In terms of solubility, the substance exhibits good solubility in organic solvents. Organic solvents such as common ethanol and ether can be fused with it to form a uniform and stable solution. However, the solubility in water is relatively limited, which is due to the polar characteristics of the molecule. In the molecule, the polarity of some structures is not well matched with the polarity of water molecules, so it is difficult to dissolve in large quantities in water.
Density is also one of its important physical properties. Compared with water, its density exhibits a specific value, which is either slightly greater than that of water or slightly less than that of water. This property has important guiding significance in practical operations such as liquid-liquid separation.
In addition, the volatility of 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol is relatively moderate, neither extremely volatile and fleeting, nor difficult to volatilize and retain for a long time. This volatility should be paid attention to during storage and use to prevent material loss due to volatilization or other related problems.
Is 4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol chemically stable?
The stability of the chemical properties of 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol is related to many aspects.
Looking at its structure, the methoxy group coexists with the tetrafluorobenzyl alcohol group, and the methoxy group has a electron supply effect, which can affect the distribution of molecular electron clouds. The introduction of fluorine atoms, due to its extremely high electronegativity, can significantly change the polarity of molecules and induce effects on adjacent chemical bonds.
Under normal conditions, due to the strong electronegativity of fluorine atoms, the carbon-fluorine bond in the molecule is quite firm, and high energy is required to break it, which gives the molecule stability to a certain extent. However, the hydroxyl group of the benzyl alcohol part has a certain activity. In certain environments, the hydroxyl group can participate in reactions such as esterification and oxidation, which shows that it is not absolutely stable.
If placed in an acidic environment, the hydroxyl group may protonate, which in turn increases its ability to leave, causing the molecule to react. In an alkaline environment, the hydroxyl group may deproton to form the corresponding alkoxide negative ion, which may also trigger further reactions.
Overall, the chemical properties of 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol are not completely stable and will vary depending on the environment and the chemicals it comes into contact with. Its stability is a relative concept that exhibits either stability or reactivity under different conditions.
What are the synthesis methods of 4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol
The synthesis method of 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol has been known for a long time. The first method can be started from 4-methoxy-2,3,5,6-tetrafluorobenzoic acid. This acid and lithium aluminum hydride are first reduced in a suitable organic solvent at a suitable temperature. Lithium aluminum hydride is a strong reducing agent, which can reduce carboxyl groups to alcoholic hydroxyl groups to obtain the target product 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol. After the reaction, the excess aluminum hydride should be handled with caution to prevent accidents.
Second, you can start with 4-methoxy-2,3,5,6-tetrafluorobenzyl halogen. The benzyl halide is reacted with a nucleophilic reagent, such as an aqueous solution of potassium hydroxide, under mild heating conditions. The halogen atom of benzyl halide is attacked by a nucleophilic reagent and undergoes a substitution reaction. The halogen atom is replaced by a hydroxyl group, and then 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol is formed. After the reaction, it needs to be separated and purified to obtain a pure product.
There are also 4-methoxy-2,3,5,6-tetrafluorobenzaldehyde as raw materials. The aldehyde is reacted with sodium borohydride in an alcohol solvent. Sodium borohydride can selectively reduce the aldehyde group to an alcohol hydroxyl group, thereby preparing 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol. After the reaction is completed, the desired product can be obtained by distillation, extraction and other means. All kinds of synthesis methods have their own advantages and disadvantages, and they need to be followed according to the actual situation.
What is the price range of 4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol on the market?
I don't know the price range of 4 - Methoxy - 2, 3, 5, 6 - tetrafluorobenzyl alcohol in the market. However, "Tiangong Kaiwu" is an ancient book describing industrial and agricultural production, and is not related to the market price of this compound. The price of this compound may vary depending on factors such as the difficulty of production, the status of supply and demand, the level of quality, the amount of purchase and the competition in the market. If you want to know the details, you should consult the chemical raw material supplier, chemical trading platform or relevant industry people. They are at the forefront of the market and often know the latest price news, or can give you an accurate answer to the price range.