4 Fluorobenzyl Sulfonyl Chloride
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
(4-FLUOROBENZYL)SULFONYL CHLORIDE
Chemical Formula C7H6ClFO2S
Molar Mass 210.64 g/mol
Appearance Colorless to light yellow liquid
Density Data needed
Boiling Point Data needed
Melting Point Data needed
Solubility Soluble in organic solvents like dichloromethane
Vapor Pressure Data needed
Flash Point Data needed
Stability Reactive, moisture - sensitive
Chemical Formula C7H6ClFO2S
Molecular Weight 210.64
Appearance Typically a colorless to light - yellow liquid
Boiling Point Around 110 - 112°C at 1 mmHg
Solubility Soluble in many organic solvents like dichloromethane, chloroform
Pungency Has a strong, pungent odor
Reactivity Highly reactive towards nucleophiles, reacts with alcohols, amines
Hazard Corrosive, can cause burns to skin and eyes
FAQ

What are the main uses of (4-fluorobenzyl) sulfonyl chloride?

(4-Hydroxyethyl) salicylaldehyde, although this substance is not detailed in "Tiangong Kaiwu", it is known today to be used in ancient times, or related to dyeing, weaving, medicine and other industries.

In dyeing and weaving, ancient dyeing workers often sought nature, using plants, minerals, etc. as sources, extracting colors to dye silk and linen. (4-Hydroxyethyl) Salicylaldehyde has a specific chemical structure, or can be used as a mordant dye. Mordant dyes can make dyes and fabrics more firmly attached, increasing the fastness of dyeing and the brilliance of color. Ancient Dyeing Workshop, in order to make the color last for a long time, has repeatedly explored the method of mordant dyeing. For example, some metal salts are used in combination with vegetable dyes, (4-hydroxyethyl) salicylaldehyde or something like this, which helps the dye to stick to the fabric, and enriches the color, adds color to the brocade, and paints colorful patterns on the silk and satin, for the use of nobles, and commends its grandeur.

As for the field of medicine, the ancients also studied Materia Medica intensively, exploring the properties of various things to cure diseases. (4-hydroxyethyl) Salicylaldehyde contains special functional groups, or has certain pharmacological activities. Ancient healers used natural substances as medicines to observe their properties and taste. This aldehyde substance may have the effects of clearing away heat, detoxifying, and relieving pain, or be used to prepare paste pill powder. However, there was no precise analysis at that time, and it only relied on practice to explore. Although the exact molecular structure was not known, it could be used empirically to save the people from diseases due to the suffering of the sick.

Although the use of (4-hydroxyethyl) salicylaldehyde was not specified in "Tiangong Kaiwu", it may have been quietly used in the folk, adding luster to the lives of the ancients and contributing to the inheritance of traditional skills and medicine.

What are the physical properties of (4-fluorobenzyl) sulfonyl chloride?

(4-Hydroxyethyl) thiazole hydrochloride is a very important chemical substance. Its physical properties exhibit a variety of characteristics.

Looking at its appearance, under room temperature and pressure, (4-Hydroxyethyl) thiazole hydrochloride is usually a white to light yellow crystalline powder, which makes it easy to identify and handle. The powder has a fine texture and is slightly shiny under light, as if it contains a unique charm.

Talking about solubility, the substance is easily soluble in water. As a common solvent, water shows a good affinity for (4-Hydroxyethyl) thiazole hydrochloride. Once it is placed in water, it can be seen to gradually dissolve and form a uniform solution after a short time. This property is of great significance in many chemical experiments and industrial applications. Because it can easily participate in various chemical reactions with the help of water solubility, or it can be used to prepare solutions of specific concentrations to meet different needs.

Furthermore, its melting point is also one of the key physical properties. (4-hydroxyethyl) thiazole hydrochloride has a specific melting point range, which is crucial for controlling its physical state transition during heating. When the temperature gradually rises to the melting point, the substance will slowly change from solid to liquid. This process requires precise temperature control to ensure the stability of its properties and prevent other side reactions caused by temperature deviations, which will affect its quality and application effect.

In addition, the substance has a certain stability in the air. In a conventional air environment, its chemical properties are not prone to significant changes in a short period of time, and it can be stored more stably. However, it should also be noted that if the storage conditions such as ambient temperature and humidity change too drastically, it may also have a slight impact on its stability. Therefore, proper storage conditions are indispensable to maintain its good physical and chemical properties and ensure its effectiveness in subsequent applications.

Is (4-fluorobenzyl) sulfonyl chloride chemically stable?

(4-Hydroxybenzyl) salicylaldehyde, its chemical properties are relatively stable. In this compound, the phenolic hydroxyl group has a certain acidity and can react with bases to form corresponding phenolic salts. However, due to the existence of hydrogen bonds in the molecule, the activity of the phenolic hydroxyl group is limited to a certain extent, making it slightly less acidic than ordinary phenols, which also increases its stability under certain conditions to a certain extent.

Its aldehyde group can participate in a variety of reactions, such as condensation reactions with compounds with active hydrogen. However, due to the steric resistance effect of ortho-hydroxyl groups, the reactivity of aldehyde groups will be reduced, and it is not as easy to react as ordinary aldehyde groups. Under common conditions, specific reaction conditions and catalysts are required to react smoothly, which also makes the compound relatively stable under normal circumstances.

In addition, the benzene ring structure endows the compound with good thermal and chemical stability. The benzene ring has a conjugated system, and the electron cloud is uniformly distributed and delocalized, which makes the benzene ring structure stable and not easy to be destroyed by general chemical reagents. Therefore, the overall (4-hydroxybenzyl) salicylaldehyde is relatively stable under common mild conditions, and it is not prone to spontaneous changes. It can maintain its chemical structure and properties for a certain period of time.

What is the preparation method of (4-fluorobenzyl) sulfonyl chloride?

The method for preparing (4-hydroxybenzyl) salicylaldehyde is to take resorcinol, put it in an appropriate amount of anhydrous ethanol, stir it to dissolve. Then slowly add the ethanol solution of p-hydroxybenzaldehyde dropwise, slowly and constantly stirring. After dripping, add an appropriate amount of glacial acetic acid as a catalyst, heat it up to a specific temperature, maintain this temperature, and continue to stir for several hours to fully react.

After the reaction is completed, cool the reaction solution, and crystals will precipitate. After that, filter it with a Brinell funnel to collect crystals, and then wash it with an appropriate amount of cold ethanol several times to remove impurities. After washing, the crystals are placed in an oven and dried at a suitable temperature to obtain the finished product of (4-hydroxybenzyl) salicylaldehyde.

This preparation method is simple to operate and the product purity is quite high. During the reaction process, factors such as temperature, drip rate and catalyst dosage have a significant impact on the yield and purity of the product. Accurate temperature control, constant drip rate, and moderate catalyst dosage can achieve better results. When preparing, also pay attention to the cleanliness of the reaction environment to avoid impurities from mixing, so as not to affect the quality of the product.

What are the precautions for (4-fluorobenzyl) sulfonyl chloride in storage and transportation?

In the storage and transportation of (tetra-hydroxyethyl) salicylaldoxime, the following things should be paid attention to:

First, the storage place must be selected in a cool, dry and well-ventilated place. This is due to the properties of (tetra-hydroxyethyl) salicylaldoxime or due to improper temperature and humidity. If it is exposed to high temperature, its chemical structure may be changed, and its efficacy or other characteristics may be damaged; if the environment is humid, it is easy to be attacked by water vapor, causing deliquescence, etc., which affects the quality.

Second, it should be separated from oxidants, acids and other substances. The oxidizing agent has strong oxidizing properties and active acid properties. (tetrahydroxyethyl) salicylaldoxime coexists with it, which is likely to trigger chemical reactions, or generate heat and gas, causing packaging damage, and even causing safety risks, such as fire and explosion.

Third, the storage area should be equipped with suitable facilities for containing and handling leaks. Once a leak occurs, it can be collected in time to prevent it from spreading around and polluting the environment. And leaks may be harmful to the human body and the environment, and need to be properly handled. According to relevant procedures, clean up in a suitable way.

Fourth, when transporting, the packaging must be tight. The road is bumpy, and if the packaging is not firm, it is easy to cause leakage of (tetra-hydroxyethyl) salicylaldoxime. Choose suitable packaging materials to ensure that it is not damaged under normal transportation vibration.

Fifth, the transportation vehicle should also be clean and free of other chemicals. Residual chemicals may react with (tetra-hydroxyethyl) salicylaldoxime, and should be protected from exposure to the sun, rain, and high temperature during transportation. High temperature in summer, long-term exposure to the sun can cause the temperature in the car to be too high; in case of rain, the packaging may be damaged due to rain soaking, endangering transportation safety and product quality.