Chemical Formula | C8H10FN |
Molecular Weight | 139.17 |
Appearance | Typically a colorless to pale yellow liquid |
Boiling Point | Approximately 187 - 189 °C |
Density | Around 1.04 g/cm³ |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Odor | Characteristic amine - like odor |
Flash Point | Approximately 65 °C |
Pka | Related to the basicity of the amine group, around 9 - 10 |
Chemical Formula | C8H10FN |
Molar Mass | 139.17 g/mol |
Appearance | Typically a colorless to pale yellow liquid |
Boiling Point | Around 177 - 179 °C |
Density | Approx. 1.04 g/cm³ |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, dichloromethane |
Flash Point | Around 58 °C |
Odor | Aminic, pungent odor |
Pka | Estimated basic pKa, around 9 - 10 |
What are the main uses of (4-fluorobenzyl) methylamine?
(4-hydroxyethyl) acetaniline is a key compound in the field of organic synthesis and is widely used in the preparation of medicine, dyes and other fine chemicals.
In the field of medicine, it is mainly used in the synthesis of various drugs. For example, the preparation of antipyretic and analgesic drug acetaminophen, (4-hydroxyethyl) acetaniline is an important intermediate. It can be converted into acetaminophen through specific chemical reaction steps. This drug has antipyretic and analgesic effects, and can effectively relieve fever and mild to moderate pain, such as headache, arthralgia, toothache, etc. It is widely used in clinical applications.
In the dye industry, (4-hydroxyethyl) acetaniline can be used as a raw material for synthetic dyes. Through a series of chemical synthesis methods, it can be made into a variety of dyes with bright color and excellent performance. These dyes are widely used in textile, printing and dyeing industries, giving fabrics rich colors and meeting people's needs for textile aesthetics. Due to its structural characteristics, the synthetic dyes perform well in terms of dyeing fastness and color stability, which can keep the fabric bright for a long time after dyeing and is not easy to fade.
In addition, in the field of fine chemicals, (4-hydroxyethyl) acetaniline also plays an important role. It can be used to prepare organic compounds with special properties, providing a key raw material base for the research and development and production of related fine chemicals, and helping to develop more high-performance, high-value-added fine chemicals to meet the diverse needs of different industrial fields and consumer markets.
What are the physical properties of (4-fluorobenzyl) methylamine?
(4-Hydroxymethyl) acrylate is a type of organic compound. Its physical properties are many and are closely related to various applications. The details are as follows:
First, looking at its properties, under normal conditions, (4-hydroxymethyl) acrylate is mostly a colorless and transparent liquid with a clear texture. This property makes it suitable for many fields that require appearance, such as the preparation of coatings and adhesives, without introducing additional color and affecting the appearance of the finished product.
Second, with regard to the boiling point, the boiling point of this compound is quite high. The characteristics of high boiling point make it difficult to vaporize and dissipate easily during heating, and the stability is good. In industrial production or application scenarios in high temperature environments, it can maintain its liquid state, maintain its original chemical structure and properties, and ensure the smooth progress of related processes.
Third, solubility is also a key property. (4-hydroxymethyl) acrylate is soluble in many organic solvents, such as ethanol, acetone, etc. Good solubility provides broad space for its formulation design. In the manufacture of coatings, organic solvents can be used to prepare to a suitable concentration, which is convenient for application coating, and can be uniformly mixed with other organic ingredients to improve the overall performance of the coating.
Fourth, in terms of viscosity, it usually has a moderate viscosity. Moderate viscosity not only ensures that it is not too thin and difficult to store during storage, but also in construction applications, such as coating, pouring, etc., it is easy to flow and spread, so as to achieve the ideal molding effect. Whether it is the preparation of thin film materials or the filling of complex molds, it can show good process adaptability.
Fifth, the density is relatively stable. The specific density makes it possible to operate according to accurate measurement when participating in various chemical reactions or mixed systems, ensuring that the reaction ratio is accurate, and the stability and uniformity of the mixed system are guaranteed, which is of great significance to the quality control of large-scale industrial production.
To sum up, the unique physical properties of (4-hydroxymethyl) acrylate have established its indispensable position in many fields such as materials science and chemical industry, providing a solid foundation for many practical applications.
What are the chemical properties of (4-fluorobenzyl) methylamine?
(4-Hydroxybenzyl) ethyl acetate, this is an organic compound. Its chemical properties are quite characteristic and closely related to many chemical reactions and applications.
Let's talk about its physical properties first. (4-Hydroxybenzyl) ethyl acetate is often colorless to pale yellow liquid, with a specific odor, and is stable at room temperature and pressure. In case of open flames and hot topics, it is flammable, which is what needs special attention.
In terms of chemical activity, the molecule contains ester groups and hydroxyl groups, which give it unique reaction characteristics. Ester groups can undergo hydrolysis reactions, and under acidic or alkaline conditions, the hydrolysis rate varies. In acidic media, the hydrolysis process is relatively mild and reversible, and after a gradual reaction, the corresponding acids and alcohols are generated; in alkaline environments, the hydrolysis reaction is more rapid and thorough, often called saponification reaction, and finally produces carboxylic salts and alcohols. The presence of the
hydroxyl group also adds a different activity to the compound. Hydroxyl groups can participate in esterification reactions, and under the action of catalysts with acids, form new ester compounds. This process is widely used in organic synthesis to construct more complex molecular structures. At the same time, hydroxyl groups are also easily oxidized, and different oxidation products such as alaldehyde, ketone or carboxylic acid can be formed according to the oxidation conditions and differences in the oxidants used.
(4-hydroxybenzyl) ethyl acetate is widely used in the field of organic synthesis. It is often used as a key intermediate in the preparation of various drugs, fragrances and fine chemicals. Due to its unique chemical properties, it can ingeniously build the required molecular framework through a series of chemical reactions, providing an effective path for the synthesis of many compounds and promoting the development and innovation of organic chemistry.
What are the preparation methods of (4-fluorobenzyl) methylamine?
The preparation method of (4-hydroxybenzyl) ethyl acetate is the key to the chemical process. In this imitation of the text of "Tiangong Kaiwu", it is described as follows:
To prepare (4-hydroxybenzyl) ethyl acetate, one method is to first take an appropriate amount of p-hydroxybenzaldehyde and place it in a clean reactor. This p-hydroxybenzaldehyde, with good color and quality, is the basis of the reaction. Next, measure a certain proportion of acetic anhydride and slowly pour it into the kettle. Acetic anhydride has active chemical properties and is essential in the reaction.
At the same time, add an appropriate amount of catalyst, this catalyst can promote the reaction to run quickly and increase the yield of the product. During the reaction process, the temperature should be controlled in a suitable range. At the beginning, it can be gradually heated to a certain temperature, so that the materials can blend with each other and initiate a reaction. At this time, the substances in the kettle quietly change, the molecules interact, and new compounds gradually emerge.
During the reaction, it is necessary to closely observe its state and stir it in a timely manner to make the materials mix evenly to ensure that the reaction is sufficient. When the reaction reaches a certain extent, the reaction process can be determined by looking at the signs of the reaction, such as the change of color, the escape of gas, etc. When the reaction is approaching the end point, the technique of separation and purification is required.
can be distilled first to remove its volatile impurities, so that the product can be initially concentrated. Then, or by the method of extraction, select a suitable extractant and extract the product from the mixture. Then through washing, drying and other steps to remove residual impurities. Finally, through fine operations such as recrystallization, pure (4-hydroxybenzyl) ethyl acetate can be obtained.
There are other methods, which can first esterify p-hydroxybenzoic acid and ethanol to obtain p-hydroxybenzoic acid ethyl ester. Then, through specific reduction steps, such as using a suitable reducing agent, under appropriate conditions, some of its groups can be reduced, and finally (4-hydroxybenzyl) ethyl acetate can be obtained. However, no matter what method, it is necessary to refine the process and abide by the procedures to obtain high-quality products.
What are the precautions for (4-fluorobenzyl) methylamine in storage and transportation?
When storing and transporting (4-hydroxybenzyl) ethyl acetate, pay attention to many key matters.
When storing, the first environmental temperature. This substance should be stored in a cool place. If the temperature is too high, it is easy to change its chemical properties, or cause decomposition and other conditions, which will damage its quality and utility. If the temperature exceeds a certain range, or the molecular structure is unstable, it will reduce its purity and affect the subsequent use effect.
Humidity is also a key factor. It should be avoided in a humid environment, moisture or cause (4-hydroxybenzyl) ethyl acetate to absorb moisture, which may induce reactions such as hydrolysis and change its chemical composition. Under humid conditions, water molecules easily interact with the substance molecules, breaking the original chemical bonds and forming other impurities.
Furthermore, the storage area should be kept well ventilated. If this substance is stored in a confined space, once leakage occurs, the harmful gas cannot be dissipated in time, which not only increases the safety risk, but also may affect the stability of the substance due to gas accumulation.
During transportation, the packaging must be stable. Suitable packaging materials need to be selected to ensure that the packaging is not damaged under normal transportation conditions such as bumps and vibrations. If the packaging is damaged, the leakage of (4-hydroxybenzyl) ethyl acetate will not only waste resources, pollute the environment, but also endanger the safety of transportation personnel.
The environment of the transportation vehicle should also be controlled, and the appropriate temperature and humidity should be maintained, just like the storage requirements, to avoid the deterioration of the material due to environmental factors. And the transportation process should be prevented from mixing with other substances that may react to prevent chemical reactions and cause safety accidents.
All of these are important points that cannot be ignored in the storage and transportation of (4-hydroxybenzyl) ethyl acetate, and must be treated with caution to ensure its quality and safety.