Name | 4-Cyano-2-fluorobenzylbromide 97% |
Chemical Formula | C8H5BrFN |
Molecular Weight | 214.03 |
Appearance | Typically a solid or viscous liquid |
Solubility | Soluble in some organic solvents like dichloromethane, less soluble in water |
Purity | 97% |
Stability | Should be stored properly to avoid decomposition, may react with nucleophiles |
Hazard | Corrosive, harmful if swallowed, inhaled or in contact with skin |
Name | 4-Cyano-2-fluorobenzylbromide 97% |
Chemical Formula | C8H5BrFN |
Molar Mass | 214.03 g/mol |
Appearance | Solid (usually) |
Purity | 97% |
What are the main uses of 4-Cyano-2-fluorobenzylbromide 97%?
4-Cyano-2-fluorobenzyl bromide (97% content) has a wide range of uses and is a key raw material in the field of organic synthesis.
From the perspective of pharmaceutical creation, it can be integrated into the molecular structure of drugs through delicate reactions. Taking the synthesis of compounds with specific curative effects as an example, it may be possible to use its unique activities of cyano and fluorine atoms to target specific biological targets and assist in the development of new drugs, such as antibacterial and antiviral drugs. With this raw material, key pharmacoactive groups can be constructed to enhance the accuracy and efficacy of drugs against pathogens.
In the field of material chemistry, it can be used as the cornerstone of functional material synthesis. After polymerization with other monomers, the material is endowed with unique electrical, optical or mechanical properties. For example, when preparing optoelectronic materials, cyanide and fluorine atoms in the structure can adjust the intermolecular force and electron cloud distribution of the material, optimize the material's luminous efficiency and charge transport ability, and are expected to be used in the manufacture of high-performance Light Emitting Diodes or solar cell materials.
In the field of fine chemical production, a variety of high-value-added products can be derived. In the synthesis of fragrances, this structure is introduced through clever chemical reactions to give fragrances unique molecular characteristics and add aroma uniqueness and stability. In the field of pesticide synthesis, its active structure can be used to create high-efficiency, low-toxicity and environmentally friendly pesticides to enhance the prevention and control of pests and diseases.
In conclusion, although the amount of 4-cyano-2-fluorobenzyl bromide is only 97%, it is of great value in many fields. With its unique structure and activity, it has injected impetus into innovation and development in various fields.
What are the storage conditions for 4-Cyano-2-fluorobenzylbromide 97%?
The storage conditions of 4-cyano-2-fluorobenzyl bromide (content 97%) are crucial to the stability and effectiveness of this substance. These chemicals are very active and easily disturbed by various factors in the surrounding environment.
Bear the brunt of the first, and you need to be careful about temperature. It should be stored in a cool place to avoid extreme heat and high temperature. At high temperatures, molecular activity surges, or chemical reactions occur unprovoked, causing it to deteriorate. Generally speaking, the temperature should be maintained in the range of 15 to 25 degrees Celsius, just like being in a mild environment, which can keep its chemical properties stable.
Humidity should not be underestimated. Moisture can easily cause chemicals to deliquescent or react with their components. Therefore, it should be placed in a dry place. If conditions permit, a desiccant, such as silica gel, can be placed in the storage place to absorb excess water vapor, ensure a dry environment, and the humidity should be controlled between 40% and 60%.
Furthermore, light is also the key. 4-Cyano-2-fluorobenzyl bromide may be sensitive to light, and light may promote its decomposition. Therefore, when stored in a dark place, it should be contained in a dark container, or placed in a dark warehouse, just like building a dark corner for it.
In addition, this chemical is toxic and corrosive, and it must be strictly isolated from other substances, especially incompatible substances, when stored. Do not co-store with acids, alkalis, etc., to prevent violent reactions. And the storage place should be well ventilated, if there is a trace of volatilization, it can be dispersed in time to avoid danger caused by accumulation. The warehouse also needs special personnel to guard, and the entry and exit registration is detailed to ensure orderly management, so as to ensure the safe storage of 4-cyano-2-fluorobenzyl bromide.
4-Cyano-2-fluorobenzylbromide 97% of synthetic methods
To prepare 4-cyano-2-fluorobenzyl bromide (content 97%), the synthesis method of 4-cyano-2-fluorobenzyl bromide (content 97%) has been recorded in many books in the past, and each method has its own strengths. Here is your description.
First, it can be started from 4-cyano-2-fluorotoluene. This compound is co-placed with N-bromosuccinimide (NBS) in a suitable reaction solvent in the presence of an initiator, such as carbon tetrachloride. Light or heat to initiate a free radical reaction. Among them, NBS is used as the bromine source, and the bromine atom is introduced at the benzyl position of toluene by radical substitution, so 4-cyano-2-fluorobenzyl bromide is obtained. After the reaction is completed, the product is purified by extraction, washing, drying, column chromatography, etc., and the target with high purity can be obtained.
Second, start from 4-cyano-2-fluorobenzoic acid. First reduce it to 4-cyano-2-fluorobenzyl alcohol. The commonly used reducing agent such as sodium borohydride-zinc chloride system reacts in alcohol solvents to obtain this alcohol mildly. Then, 4-cyano-2-fluorobenzyl alcohol interacts with hydrobromic acid or phosphorus tribromide. After nucleophilic substitution, the hydroxyl group is replaced by bromine to obtain 4-cyano-2-fluorobenzyl bromide. After the reaction, it is treated by distillation, recrystallization and other means to achieve the purity requirement of 97%.
Third, 4-cyano-2-fluoroaniline is used as a raw material and is reacted by diazotization to obtain diazonium salt. Then it is co-heated with cuprous bromide and hydrobromic acid, and the Sandmeier reaction occurs. The amino group is replaced by bromine, and 4-cyano-2-fluorobromobenzene is indirectly obtained. Subsequently, under suitable conditions, the benzyl bromide structure is introduced through bromomethylation reaction. This process requires the synergistic action of paraformaldehyde, hydrobromic acid and suitable catalysts. After a series of purification steps, 4-cyano-2-fluorobenzyl bromide with a content of 97% is obtained.
The above methods have their own advantages and disadvantages. The experimenter should choose carefully according to the actual situation, such as the availability of raw materials, cost, difficulty of reaction conditions, etc., in order to achieve the purpose of efficient synthesis.
4-Cyano-2-fluorobenzylbromide 97% of the market price
It is 4-cyano-2-fluorobenzyl bromide with a purity of 97%, and its market price is about geometric. The price of this chemical often varies due to various reasons, and it is difficult to be sure.
In the past, the price of chemical materials was related to supply and demand, manufacturing costs, and fluctuations in market conditions. If the demand for this product is strong and the supply is limited, the price will increase; conversely, if the supply exceeds the demand, the price may drop.
Manufacturing cost is also a major factor. The price of raw materials, the simplicity of the preparation process, and the amount of energy consumption all affect its cost. If the raw materials are rare and difficult to find, or the preparation requires exquisite craftsmanship and huge energy consumption, the cost is high, and the price follows.
Furthermore, the fluctuation of market conditions has a deep impact. Economic boom and bust, policies and decrees, and sudden events can all cause price fluctuations. Economic prosperity, demand may increase, prices may rise; policy changes, such as stricter environmental regulations, or production restrictions, and prices may also change.
As for 4-cyano-2-fluorobenzyl bromide, according to common sense, if the batch is small, such as laboratory grade dosage, the price per gram may be in the tens to hundreds of gold; if it is purchased in large quantities for industrial grade, due to economies of scale, the unit price may be discounted, and the price per kilogram may be in the thousands of gold. However, this is only a guess. The actual price should be subject to the quotations of various merchants in the current market. It is necessary to consult the chemical suppliers in detail to obtain the exact number.
4-Cyano-2-fluorobenzylbromide 97% Quality Standard
The 97% Quality Standard for 4-Cyano-2-Fluorobenzyl Bromide is a criterion for the quality of this chemical. The first and foremost is related to the appearance and morphology, when it is in a specific state, or a crystal clear solid, or a clear and transparent liquid, free of impurities and foreign matter.
Regarding purity, the 97% purity label is the key. It needs to be determined in detail by accurate analytical methods, such as high-performance liquid chromatography (HPLC), gas chromatography (GC), etc. The composition of 4-cyano-2-fluorobenzyl bromide must reach 97%, and the fluctuation should not exceed a very small range to ensure the stability and reliability of its chemical properties.
Impurity content is also an important consideration. All kinds of impurities, such as related organic impurities, inorganic impurities, etc., must be strictly limited. Organic impurities or intermediate products and by-products derived from the synthesis process should be minimal in content so as not to affect the main properties of the product. Inorganic impurities, such as metal ions, must also follow a very low limit standard to avoid adverse subsequent use.
Physical properties such as melting point or boiling point are also part of the Quality Standard. For solid 4-cyano-2-fluorobenzyl bromide, the melting point should be in a specific temperature range, which has been accurately determined and verified. For liquids, the boiling point must meet the established range, which can help to determine its purity and quality.
In addition, the moisture content cannot be ignored. Excessive moisture, or abnormal chemical reactions, or affect its storage stability. Therefore, appropriate methods, such as Carl Fischer's method, must be used to determine and control the moisture at a suitable low level. < Br >
In terms of packaging, it should be solid and well sealed to prevent external factors such as air, moisture, light, etc. from affecting it, and ensure that the quality of the product is safe during storage and transportation. All of these together make up 97% of the Quality Standard of 4-cyano-2-fluorobenzyl bromide.