Name | 4-Chloro-2,6-difluorobenzyl alcohol |
Chemical Formula | C7H5ClF2O |
Molar Mass | 178.563 g/mol |
Appearance | White to off - white solid |
Melting Point | 54 - 57 °C |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone, dichloromethane |
Chemical Formula | C7H5ClF2O |
Molecular Weight | 180.56 |
Appearance | Solid or liquid (depending on conditions) |
Physical State At Room Temperature | Typically solid |
Boiling Point | Data may vary, needs specific experimental determination |
Melting Point | Data may vary, needs specific experimental determination |
Density | Data may vary, needs specific experimental determination |
Solubility In Water | Low solubility, being an organic compound |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
Flash Point | Data may vary, needs specific experimental determination |
Odor | Characteristic organic odor |
Stability | Stable under normal conditions but may react with strong oxidizing agents |
What is the main use of 4-Chloro-2,6-difluorobenzyl alcohol?
4-Chloro-2,6-difluorobenzyl alcohol is also an organic compound. It has a wide range of uses and has important applications in various fields such as medicine, pesticides and material science.
In the field of medicine, it is often a key intermediate in the synthesis of many drugs. Due to its unique chemical structure, it can endow drugs with specific physiological activities and pharmacological properties. For example, when synthesizing some antibacterial drugs, this compound can be used as a starting material. After a series of chemical reactions, the core structure of drug activity can be constructed, which helps to improve the antibacterial effect and selectivity of drugs, and contributes greatly to human health and well-being.
In the field of pesticides, 4-chloro-2,6-difluorobenzyl alcohol is also an important component in the synthesis of new pesticides. With its structural characteristics, high-efficiency, low-toxicity and environmentally friendly pesticides can be developed. Such pesticides can effectively control crop diseases and pests, ensure crop yield and quality, reduce the adverse impact of traditional pesticides on the environment, and meet the current needs of green agriculture development.
In the field of materials science, this compound can participate in the synthesis of materials with special properties. For example, in the synthesis of polymer materials, the introduction of this structural unit can improve the thermal stability, mechanical properties and optical properties of materials. New materials developed therefrom may be widely used in electronics, optics and other fields, promoting technological progress in related industries.
In summary, 4-chloro-2,6-difluorobenzyl alcohol plays an important role in many fields due to its unique structure, providing key support for the development of various fields and has broad prospects.
What are the physical properties of 4-Chloro-2,6-difluorobenzyl alcohol?
4-Chloro-2,6-difluorobenzyl alcohol is one of the organic compounds. It has several physical properties and may have applications in chemical, pharmaceutical and other fields.
Looking at its properties, under room temperature, 4-chloro-2,6-difluorobenzyl alcohol is mostly in a colorless to light yellow liquid state, with a clear and transparent appearance. It has a special odor, although it is difficult to describe exactly, it is also one of its characteristics for those who are familiar with it.
When it comes to the boiling point, it is about a specific temperature range, which is due to the intermolecular force. Its boiling point can help to separate and purify this compound, which is very important in the chemical process. When heated to the boiling point, the substance changes from liquid to gaseous state, and pure 4-chloro-2,6-difluorobenzyl alcohol can be collected by means of condensation.
Melting point is also an important physical property. The melting point of this compound determines its state in a low temperature environment. If the ambient temperature is lower than the melting point, 4-chloro-2,6-difluorobenzyl alcohol will solidify into a solid state.
In terms of solubility, 4-chloro-2,6-difluorobenzyl alcohol has good solubility in organic solvents such as ethanol and ether. This property makes it a reactant or intermediate in organic synthesis reactions, and can participate in the reaction in a suitable solvent system. However, its solubility in water is not good, which is due to the difference between molecular polarity and water molecular polarity.
Density is also a property that cannot be ignored. Its density is different from that of water. This property affects the stratification of substances in mixed systems and is of great significance in the separation operation of chemical production.
In addition, the refractive index of 4-chloro-2,6-difluorobenzyl alcohol also has a specific value. This physical property can be used to identify the compound and provide a certain reference in the application or research of optical materials.
In summary, the physical properties of 4-chloro-2,6-difluorobenzyl alcohol, such as appearance, boiling point, melting point, solubility, density, and refractive index, are interrelated and important, and play a key role in its research, production, and application.
What is the chemical synthesis method of 4-Chloro-2,6-difluorobenzyl alcohol?
The chemical synthesis of 4-chloro-2,6-difluorobenzyl alcohol is an important topic in the field of organic synthesis. In the past, several ways were often followed to synthesize this compound.
One of them can be started from the corresponding halogenated aromatics. Halogenated aromatics are used as raw materials and hydroxyl groups are introduced by nucleophilic substitution reaction. First, the halogenated aromatics are placed in a suitable reaction medium, such as polar organic solvents, and alkali substances, such as potassium carbonate and sodium hydroxide, are added to adjust the pH of the reaction system to promote the substitution of halogen atoms by nucleophilic testers. In this process, the choice of nucleophilic reagents is very critical, and compounds containing hydroxyl groups are often used as nucleophilic reagents, such as alkoxides. The reaction temperature and time also need to be finely regulated. Generally, the reaction temperature is between room temperature and higher temperature. After several hours to tens of hours of reaction, the reaction can reach the expected level.
Second, it can be achieved step by step by halogenation and hydroxylation of aromatic hydrocarbons. Halogenate the aromatic hydrocarbons first, and precisely control the amount of halogenating reagents and reaction conditions. For example, select an appropriate halogenating agent, such as chlorine gas, bromine, etc., in the presence of a catalyst, halogenate the aromatic hydrocarbons at specific locations to generate halogenated aromatics containing chlorine and fluorine. Then the halogenated aromatic hydrocarbon is hydroxylated, and the method of synergistic action between metal salts and hydroxyl-containing reagents is often used to optimize the reaction parameters, such as reaction temperature, solvent type, reactant ratio, etc., to achieve the conversion to the target product 4-chloro-2,6-difluorobenzyl alcohol.
Third, there is also a synthesis strategy using benzaldehyde derivatives as starting materials. Benzaldehyde derivatives are first halogenated, chlorine and fluorine atoms are introduced at specific positions in the benzene ring, and then the aldehyde group is converted into hydroxyl group by reduction reaction. In the reduction process, the choice of reducing agent is crucial. Commonly used reducing agents such as sodium borohydride, lithium aluminum hydride, etc., according to the reaction scale, product purity requirements and other factors, the reducing agent is reasonably selected, and the reduction reaction conditions are optimized to obtain 4-chloro-2,6-difluorobenzyl alcohol efficiently.
All synthesis methods have their own advantages and disadvantages, and the appropriate synthesis path should be carefully selected according to the actual demand, such as the availability of raw materials, cost considerations, product purity requirements and many other factors.
What is the price range of 4-Chloro-2,6-difluorobenzyl alcohol on the market?
The price of 4-chloro-2,6-difluorobenzyl alcohol in the market varies for many reasons. The range of its price is difficult to determine.
This product is widely used in the chemical industry, and changes in its demand can cause price fluctuations. If the chemical industry has a large increase in demand for this product at a certain time, the supply exceeds the demand, and the price may rise; conversely, the demand is weak, and the supply exceeds the demand, the price may fall.
Furthermore, the cost of its production is also a major factor. The price of raw materials, the simplicity of the production process, and the amount of energy consumption all affect the cost. If the price of raw materials increases, or the cost is high due to the complexity of the production process, the price between the markets will also rise; if the cost decreases, the price may decrease.
The difference between regions is also related to the price. Different places have different prices due to logistics costs and market supply and demand patterns. In places with convenient transportation and fierce market competition, the price may be relatively reasonable; and in remote places, due to high logistics costs, the price may be higher.
However, according to common market conditions, the price of 4-chloro-2,6-difluorobenzyl alcohol per kilogram may range from hundreds to thousands of yuan. This is only a rough estimate. The actual price must be carefully checked by the market dynamics and consulted with suppliers or distributors before a more accurate estimate can be obtained.
What are the precautions for 4-Chloro-2,6-difluorobenzyl alcohol in storage and transportation?
4-Chloro-2,6-difluorobenzyl alcohol is a genus of organic compounds. When storing and transporting, many things need to be taken care of.
First word storage. This substance should be placed in a cool, dry and well-ventilated place. Cover it in a high temperature, humid environment, or risk of deterioration. For example, if it is extremely hot in summer, if it is stored in a warehouse without ventilation, the temperature is too high, or its chemical properties change. And it must be kept away from fire and heat sources. Because the flammability is unknown, open flames and hot topics can be dangerous. It should also be stored separately from oxidizing agents, acids, bases, etc., and cannot be mixed. Due to its chemical activity, it encounters with various such substances, or reacts violently, causing unexpected changes.
As for transportation, caution is also required. Packaging must be tight to prevent leakage. Use appropriate packaging materials, such as corrosion-resistant containers, to ensure that there is no leakage during transportation. During transportation, ensure that the container does not tip, fall, or damage. Driving routes also need to be carefully planned to avoid densely populated and environmentally sensitive places such as water sources and residential areas, in case of leakage and serious harm. Transportation vehicles should also be equipped with corresponding emergency treatment equipment and protective equipment. If there is an emergency, they can be responded to in time to reduce the damage.
In short, the storage and transportation of 4-chloro-2,6-difluorobenzyl alcohol are all related to safety and quality, and all details should not be ignored, so as to ensure that everything goes smoothly and is harmless.