What is the chemical structure of 4-Amino-5-Chloro-2-Ethoxy-N- ((4- (4-Fluorobenzyl) Morpholin-2-Yl) Methyl) Benzamide?

This is the name of an organic compound. In order to clarify its chemical structure, it is necessary to analyze the meaning of each part of the name. "4 - Amino - 5 - Chloro - 2 - Ethoxy - N - (4 - (4 - Fluorobenzyl) Morpholin - 2 - Yl) Methyl) Benzamide", "Benzamide" indicates the main structure of benzamide and is the root of the compound. " 4 - Amino "Epibenzamide benzene ring has an amino ($- NH_ {2} $) substitution at the 4th position;" 5 - Chloro "means that the benzene ring has a chlorine atom ($-Cl $) substitution at the 5th position;" 2 - Ethoxy "means that the benzene ring has an ethoxy ($- OCH_ {2} CH_ {3} $) substitution at the 2nd position.

Furthermore," N - ((4 - (4 - Fluorobenzyl) Morpholin - 2 - Yl) Methyl) "is a substituent on the nitrogen atom attached to the benzamide carbonyl group." ( In 4 - (4 - Fluorobenzyl) Morpholin - 2 - Yl) "," Morpholin "is a morpholine ring, and 4-fluorobenzyl (4 dollars - F - C_ {6} H_ {4} CH_ {2} - $) is connected to the 2-position methylene ($- CH_ {2} - $), which is then connected to the benzamide nitrogen atom.

Its structure can be roughly drawn, first draw the basic structure of benzamide, and add an amino group, a chlorine atom, and an ethoxy group at the corresponding position of the benzene ring. Then, according to the description, the substituent on the nitrogen atom is constructed, and the morpholine ring is connected to the 4-fluorobenzyl group at the 4 position, and the 2 position is connected to the benzamide nitrogen atom through the methylene, so that the chemical structure of the compound is obtained.

What are the main uses of 4-Amino-5-Chloro-2-Ethoxy-N- ((4- (4-Fluorobenzyl) Morpholin-2-Yl) Methyl) Benzamide?

4-Amino-5-chloro-2-ethoxy-N- ((4- (4-fluorobenzyl) morpholine-2-yl) methyl) benzamide, which is mostly used in the field of pharmaceutical research and development. The way of medicine is to seek a cure for diseases, and the effect of medicine is essential. This compound is used in the creation of medicine, or as an active ingredient, and can act on specific physiological targets to adjust the abnormality of the body and achieve the work of healing diseases.

The diseases of the human body are caused by physiological imbalances, or due to the invasion of evil energy, or due to the loss of viscera. When developing new drugs, physicians must look for substances that can precisely adjust imbalances. 4-Amino-5-chloro-2-ethoxy-N - ((4- (4-fluorobenzyl) morpholine-2-yl) methyl) benzamide, through exquisite chemical design and synthesis, has specific chemical structures and properties, and can fit with targets in the body, just like tenon and mortise.

In the treatment of cancer, many drugs target the specific molecular mechanism of cancer cells. This compound may block the proliferation signaling pathway of cancer cells, causing cancer cells to lose their ability to multiply and gradually apoptosis, as if cutting off their source of vitality. Or in the treatment of nervous system diseases, acting on the metabolism or receptors of neurotransmitters, in order to restore the normal nerve conduction and relieve the suffering of patients with confusion and limb paralysis.

Furthermore, in inflammatory diseases, it may regulate inflammation-related cytokines and signaling molecules, reduce inflammation, and eliminate redness, swelling, heat and pain. However, although its application prospect is promising, it also needs to undergo rigorous pharmacological and toxicological tests to check the accuracy and safety of its efficacy before it can be used in clinical practice and relieve the disease of the world.

4-Amino-5-Chloro-2-Ethoxy-N- (4- (4-Fluorobenzyl) Morpholin-2-Yl) Methyl) Benzamide?

To prepare 4-amino-5-chloro-2-ethoxy-N- ((4- (4-fluorobenzyl) morpholine-2-yl) methyl) benzamide, there are many methods, the following is one.

First take 4-chloro-2-ethoxy benzoic acid and use thionyl chloride as an agent to form an acid chloride. This step needs to be at a suitable temperature and the environment is dry. A slight excess of thionyl chloride can promote the complete reaction.

After obtaining acyl chloride, react with 2- (aminomethyl) -4 - (4-fluorobenzyl) morpholine. This reaction is carried out smoothly in an organic solvent such as dichloromethane or N, N-dimethylformamide, with acid binding agents such as triethylamine or pyridine, to obtain 4-chloro-5-ethoxy-N - ((4- (4-fluorobenzyl) morpholine-2-yl) methyl) benzamide.

Then, in a suitable reduction system, such as palladium-carbon hydrogenation, or lithium aluminum hydride, etc., the chlorine atom of 4-chloro-5-ethoxy-N - (4 - (4 - fluorobenzyl) morpholine-2 - yl) methyl) benzamide is reduced for dechlorination, and the nitro group on the benzene ring is reduced to an amino group to obtain the target product 4-amino-5-chloro-2-ethoxy-N - ((4 - (4 - fluorobenzyl) morpholine-2 - yl) methyl) benzoyl Amine. However, lithium aluminum hydride has high activity and must be operated with caution in a low temperature and anhydrous environment.

After each step of the reaction, a suitable separation and purification method, such as column chromatography, recrystallization, etc., is required to obtain a pure product to facilitate the next step of the reaction. This synthesis path is only an example, and the actual operation can be optimized according to factors such as raw materials, equipment, and cost.

How safe is 4-Amino-5-Chloro-2-Ethoxy-N- (4- (4-Fluorobenzyl) Morpholin-2-Yl) Methyl) Benzamide?

4 - Amino - 5 - Chloro - 2 - Ethoxy - N - ((4 - (4 - Fluorobenzyl) Morpholin - 2 - Yl) Methyl) Benzamide is a complex organic compound. In terms of its safety, it needs to be studied many times, and many factors are intertwined, making it difficult to make a simple conclusion.

In the past, when exploring the safety of new compounds, it often followed a number of paths. The first major toxicological study is an important way to gain insight into its potential harm to organisms. Acute, subacute and chronic toxicity tests should be conducted in different experimental animals. Observe whether it causes acute poisoning symptoms in organisms at high doses, such as abnormal behavior, organ damage, etc.; in subacute and chronic tests, carefully investigate whether there are progressive lesions, such as organ function decline, histopathological changes, etc. when exposed to long-term low doses.

Furthermore, consider its mutagenicity and carcinogenicity. Mutagenicity is related to whether the compound can cause mutations in the genetic material of the organism, which is often used in parallel with in vitro cell tests and in vivo animal tests. Carcinogenicity studies are longer and more rigorous, and long-term observation of experimental animals is required to see if there are tumors.

In addition, the metabolic properties of the compound are also key. It is clear that its metabolic pathways and products in organisms are due to some metabolites or more toxic than the original compound.

However, we do not know the detailed research data of 4 - Amino - 5 - Chloro - 2 - Ethoxy - N - ((4 - (4 - Fluorobenzyl) Morpholin - 2 - Yl) Methyl) Benzamide, which can only be speculated. If its chemical structure contains common toxic groups, such as some heavy metal element structures, active halogenated groups, etc., there may be a high risk of toxicity; conversely, if the structure is stable and similar to known low-toxic compounds, the safety may be relatively high. However, this is all speculation, and the conclusive conclusion is still supported by detailed experimental data.

What is the market outlook for 4-Amino-5-Chloro-2-Ethoxy-N- (4- (4-Fluorobenzyl) Morpholin-2-Yl) Methyl) Benzamide?

Today, the name of the compound is 4 - Amino - 5 - Chloro - 2 - Ethoxy - N - (4 - (4 - Fluorobenzyl) Morpholin - 2 - Yl) Methyl) Benzamide. Its market prospects are still to be explored. The fog has not dissipated, but there is still hope.

In the field of Guanfu medicine, this compound may have potential medicinal value. If it can demonstrate good pharmacological activity, play a role in targeting specific disease targets, or emerge in the development of new drugs. To cover today's pharmaceutical market, there is a hunger for new, efficient and safe drugs. If this compound is proved to be curative and disease-free through rigorous experiments and research, it will surely attract the attention of pharmaceutical companies, and then invest resources in in-depth development, which is expected to occupy a place in the market.

However, it is also necessary to be clear that the road to new drug development is full of thorns. From compound discovery, to pre-clinical research, clinical trials, and approval for marketing, every step needs to undergo rigorous tests. And the market competition is fierce, with many similar drugs or potential alternatives. If this compound cannot stand out in terms of efficacy, safety, cost-effectiveness, etc., it may be difficult to break through the siege and gain a foothold in the market.

Furthermore, the chemical industry may also have its uses. If it has unique chemical properties, it can be used as an intermediate to participate in the synthesis of other high-value-added compounds, and can also find business opportunities in the fine chemical industry. However, factors such as the changing chemical market, fluctuations in raw material prices, and stricter environmental protection policies will all affect its industrialization process and market prospects.

In summary, the market prospect of 4 - Amino - 5 - Chloro - 2 - Ethoxy - N - (4 - (4 - Fluorobenzyl) Morpholin - 2 - Yl) Methyl) Benzamide, opportunities and challenges coexist. Only with solid scientific research, accurate market positioning, and flexible business strategies can we have the opportunity to clear the fog and achieve great results in the market.