4 Amino 5 Chloro 2 Ethoxy N 4 4 Fluorobenzyl Morpholin 2 Yl Methyl Benzamide
4-amino-5-chloro-2-ethoxy-N- what is the chemical structure of {[4- (4-fluorobenzyl) morpholin-2-yl] methyl} benzamide
4 - amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) morpholin - 2 - yl] methyl} benzamide is the name of an organic compound. To clarify its chemical structure, it is necessary to parse it from the name.
"4 - amino" shows that the fourth position of the benzene ring has an amino group (-NH2O); "5 - chloro" means that the fifth position of the benzene ring is connected with a chlorine atom (-Cl); "2 - ethoxy" indicates that the second position of the benzene ring is connected to an ethoxy group (-OCH < CH > CH).
"Benzamide" indicates that the core of this compound is benzamide structure. "N - {[4 - (4 - fluorobenzyl) morpholin - 2 - yl] methyl}" indicates that the nitrogen atom is connected to a complex side chain.
Wherein, {[4- (4 - fluorobenzyl) morpholin - 2 - yl] methyl} part, 4- (4 - fluorobenzyl) means that there is a 4-fluorobenzyl group (4 - F - C H CH ² -) in the 4-position of the morpholine ring, and the 4-position of the benzyl group has a fluorine atom; and the 2-position of the morpholine ring is connected to the methylene (-CH ² -), which is then connected to the nitrogen atom of benzamide. < Br >
The chemical structure of this compound is composed of a benzene ring, a variety of substituents and complex side chains. Each part is connected in an orderly manner according to the naming convention to construct a specific chemical structure to demonstrate its unique chemical properties and potential applications.
4-amino-5-chloro-2-ethoxy-N- What are the physical properties of {[4- (4-fluorobenzyl) morpholin-2-yl] methyl} benzamide
4 - amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) morpholin - 2 - yl] methyl} benzamide is an organic compound. Its physical properties are crucial for its application in chemical synthesis and drug development.
The appearance of this compound is often white to quasi-white crystalline powder, which is easy to observe and handle. Its melting point is within a specific range. After experimental determination, it is about [X] ° C. The accurate determination of the melting point is of great significance to determine its purity and stability. Due to changes in the melting point or the existence of implied impurities, its quality and properties are affected.
The solubility of this compound is also an important physical property. In organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), it exhibits good solubility and can be uniformly dispersed, which is conducive to participating in various chemical reactions. However, its poor solubility in water may limit its application in aqueous systems.
Its density is [X] g/cm ³. As an inherent property of matter, density is indispensable in practical operations such as the conversion of mass and volume of the compound.
In addition, the compound has certain stability and can exist stably under normal temperature, pressure and dry environment. However, when encountering strong oxidizing agents, strong acids and alkalis, chemical reactions may occur, causing structural changes.
The above physical properties, such as appearance, melting point, solubility, density and stability, are of great significance for in-depth understanding of the characteristics and applications of 4-amino-5-chloro-2-ethoxy-N - {[4 - (4 - fluorobenzyl) morpholin-2 - yl] methyl} benzamide, and provide a solid foundation for subsequent research and practice.
4-amino-5-chloro-2-ethoxy-N- what is the main use of {[4- (4-fluorobenzyl) morpholin-2-yl] methyl} benzamide
4 - amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) morpholin - 2 - yl] methyl} benzamide is an organic compound with a wide range of applications. In the field of pharmaceutical research and development, this compound can be used as a key intermediate to create new drugs. Due to its specific chemical structure or unique biological activity, it can play a role in specific disease targets, such as anti-tumor, antibacterial, etc.
In pharmaceutical chemistry, chemists can explore the structure-activity relationship by modifying the structure of the compound to optimize drug performance, improve efficacy and safety. For example, changing its side chain or substituent, or can adjust the affinity of drugs and targets, enhance its selectivity, and reduce the adverse effects on normal cells.
In the field of organic synthesis, this compound can be used as the cornerstone of complex molecular construction. With its multi-activity check point, chemists can connect it with other molecular fragments through various organic reactions to synthesize compounds with more complex structures, expand the boundaries of organic synthesis, and provide possibilities for the creation of new materials and new functional molecules. < Br >
And because of its structure containing nitrogen, oxygen, chlorine, fluorine and other heteroatoms, compounds are endowed with unique physical and chemical properties, which may have potential applications in materials science, such as as as components of functional materials, exhibiting special electrical, optical or mechanical properties.
4-amino-5-chloro-2-ethoxy-N- are the synthesis methods of {[4- (4-fluorobenzyl) morpholin-2-yl] methyl} benzamide
To prepare 4 - amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) morpholin - 2 - yl] methyl} benzamide, the method of organic synthesis is often followed. There are many methods, and they are selected to be described in brief.
First, the structure of the target molecule is constructed one by one through a multi-step reaction with appropriate starting materials. The compound containing benzene ring can be used as the base to introduce chlorine atoms, ethoxy groups and other functional groups. For example, a specific benzene derivative is introduced into the chlorine atom at a specific position of the benzene ring through halogenation reaction. The method of halogenation can be used with chlorinated reagents, such as thionyl chloride, phosphorus oxychloride, etc., depending on the activity of the substrate and the reaction conditions, the appropriate one can be selected. When ethoxy is introduced, the nucleophilic substitution reaction can be used to react with halogenated benzene derivatives such as sodium ethanol to form a 2-ethoxy structure.
Then, the amine-containing part is constructed. The amine group can be reduced by nitro, and the nitro group on the benzene ring can be converted into 4-amino by suitable reducing agents, such as hydrogen-palladium-carbon, iron-hydrochloric acid and other systems. < Br >
Furthermore, the fractions containing {[4 - (4 - fluorobenzyl) morpholin-2 - yl] methyl} were synthesized. The 4 - (4 - fluorobenzyl) morpholine was prepared first, and 4 - fluorobenzyl halogen was obtained by nucleophilic substitution reaction with morpholine. After that, the product was reacted with a suitable reagent, and a methyl group was introduced at the 2 - position, and then connected to the aforementioned fragment containing benzamide structure. In this connected step, or with condensation reagents, such as carbodiimide (DCC, EDCI, etc.), under appropriate alkali catalysis, amide bonds are formed to obtain the target product 4-amino-5-chloro-2-ethoxy-N - {[4 - (4 - fluorobenzyl) morpholin-2 - yl] methyl} benzamide. Each step of the reaction needs to be carefully controlled by temperature and time, and the solvent and catalyst should be selected to improve the yield and purity, and the products in each step often need to be separated and purified, such as column chromatography and recrystallization, to ensure the smooth subsequent reaction.
4-amino-5-chloro-2-ethoxy-N- {[4- (4-fluorobenzyl) morpholin-2-yl] methyl} benzamide
4 - amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) morpholin - 2 - yl] methyl} benzamide is a complex organic compound. There are many precautions for the safety of this substance, and let me tell them one by one.
First of all, this substance involves chemical synthesis experiments, and it needs to be strictly followed in laboratory operations. Many of the reagents used in organic synthesis are toxic, corrosive or flammable. Just like the process of synthesizing this compound, the raw materials, solvents involved may have a pungent odor, or can be absorbed through the skin and cause poisoning. Therefore, the experimenter must wear complete protective equipment, such as laboratory clothes, gloves, goggles, etc., to prevent chemical substances from contacting the body. And the experimental environment must be well ventilated, with effective ventilation equipment to expel harmful gases in time.
Furthermore, the storage of this compound should also be cautious. It should be placed in a dry, cool and ventilated place, away from fire and heat sources. Because of its special chemical structure, or sensitive to temperature and humidity, improper storage or deterioration will affect subsequent use, or even cause safety accidents.
In addition, when disposing of this compound waste, it must not be discarded at will. It must be collected in accordance with relevant environmental regulations, sorted and disposed of properly. Because it may contain heavy metals and toxic organic matter, if it enters the environment, it will cause environmental pollution, endanger ecological balance and human health.
Again, in the stage of studying its properties and uses, if this substance is involved in animal experiments, the experimenter must follow the principles of animal ethics. Make sure that the experimental animals are properly cared for, the experimental process is humane, and the pain is minimized. Because the compound may have unknown effects on animal physiology, closely monitor the animal's state during the experiment and record the data in detail.
At the end, if you accidentally come into contact with this compound, or splash it into your eyes or skin, be sure to rinse it with plenty of water immediately. If symptoms persist or worsen, seek medical attention immediately. In short, treat this complex organic compound with caution and meticulousness to ensure the safety of personnel and the environment.
