Chemical Formula | C26H30ClFN4O4 |
Molecular Weight | 519.00 |
Iupac Name | 4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2-morpholinyl]methyl]benzamide |
Appearance | Solid (predicted) |
Solubility | Solubility in water is low (predicted) |
Logp | Calculated logP value indicates some lipophilicity |
Vapor Pressure | Very low vapor pressure (predicted) |
Chemical Formula | C25H29ClFN3O4 |
Molecular Weight | 491.97 |
Appearance | Solid (usually) |
Boiling Point | N/A (estimated high based on its structure and lack of volatile groups) |
Solubility In Water | Low (due to non - polar aromatic and bulky groups) |
Solubility In Organic Solvents | Soluble in common organic solvents like DMSO, DMF |
Density | N/A (but can be estimated based on similar compounds' density range) |
Pka | N/A (related to the basicity/acidity of functional groups, no value given) |
Logp | Estimated to be positive (hydrophobic due to aromatic and fluorobenzyl groups) |
4-Amino-5-chloro-2-ethoxy-N- what is the chemical structure of {[4- (4-fluorobenzyl) -2-morpholinyl] methyl} benzamide?
This is the naming of an organic compound. To clarify its chemical structure, it can be analyzed according to the naming rules. "4 - Amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) -2 - morpholinyl] methyl} benzamide", where "benzamide" is the parent nucleus of benzamide, it can be seen that this compound uses benzamide as the basic structure.
"4-Amino" benzamide benzene ring at position 4 is connected with an amino group ($- NH_ {2} $); "5-chloro" at position 5 is connected with a chlorine atom ($-Cl $); "2-ethoxy" refers to position 2 is connected with an ethoxy group ($- OCH_ {2} CH_ {3} $).
And the "N - {[4 - (4 - fluorobenzyl) -2 - morpholinyl] methyl}" part indicates that the nitrogen atom ($N $) is connected to a complex group. In this group, "[4 - (4 - fluorobenzyl) -2 - morpholinyl]" is a specific structure, "4 - fluorobenzyl" is 4 - fluorobenzyl ($F - C_ {6} H_ {4} - CH_ {2} - $), connected to the morpholinyl ring at position 4, and the morpholinyl ring at position 2 is connected to the nitrogen atom of benzamide through methylene ($- CH_ {2} - $).
In summary, the chemical structure of this compound is based on benzamide as the core, with amino group, chlorine atom, ethoxy group connected at a specific position in the benzene ring, and morpholine methyl derivative group containing 4-fluorobenzyl group connected to the nitrogen atom. Its structure is complex and delicate, and the wonders of organic chemistry can be seen here.
What are the main uses of 4-Amino-5-chloro-2-ethoxy-N- {[4- (4-fluorobenzyl) -2-morpholinyl] methyl} benzamide?
4-Amino-5-chloro-2-ethoxy-N - {[4 - (4-fluorobenzyl) -2-morpholinyl] methyl} benzamide, this is an organic compound. It has a wide range of uses and is of great significance in the field of medicine.
Looking at pharmaceutical research and development, this compound may have unique pharmacological activities. Many drug research and development are dedicated to finding potential active ingredients, and such organic compounds are often the key starting points. It may interact with specific biological targets, such as certain enzymes, receptors, etc., by regulating specific physiological processes in organisms, to achieve the purpose of treating diseases. For example, in the development of anti-tumor drugs, many new compounds have been found to interfere with the proliferation and metastasis of tumor cells. This compound may also play a role in such mechanisms, bringing new opportunities for the development of anti-cancer drugs.
In medical research, it can be used as a tool compound. With its unique structure and properties, researchers can deeply explore the complex physiological and pathological mechanisms in organisms. For example, by observing its impact on cell signaling pathways, the occurrence and development of specific diseases can be clarified, providing a solid theoretical basis for the subsequent formulation of precision treatment strategies.
In addition to the pharmaceutical field, in the chemical industry, it may be used to synthesize other more complex and special properties materials. Due to the structural modification and transformation between organic compounds through various chemical reactions, this compound may serve as an important intermediate, providing the possibility for the preparation of functional materials, such as special polymer materials.
However, its specific uses still need to be determined based on in-depth experiments and research, and many potential application values remain to be further explored and explored by researchers.
4-Amino-5-chloro-2-ethoxy-N- What is the preparation of {[4- (4-fluorobenzyl) -2-morpholinyl] methyl} benzamide?
4 - Amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) -2 - morpholinyl] methyl} benzamide is a rather complex organic compound. The preparation method is as follows:
When starting, carefully select suitable starting materials. Benzoic acid derivatives with specific substituents can be selected. The benzene ring of this derivative should be pre-equipped with groups that can be modified by subsequent reactions, such as chlorine atoms, ethoxy groups, etc., as the basis for constructing the benzamide part of the target molecule.
First, for benzoic acid derivatives, chlorine atoms can be precisely introduced at specific positions through halogenation reaction to achieve the 5-chlorine substitution structure in the target product. This halogenation reaction needs to be carried out under suitable reaction conditions, such as selecting suitable halogenating reagents, such as thionyl chloride, etc., and controlling the reaction temperature and time to ensure that chlorine atoms are selectively substituted in the desired position.
Second, the introduction of ethoxy groups can be achieved by means of nucleophilic substitution reaction. Ethanol and a suitable base are selected, and under heating conditions, the ethoxy group of ethanol is nucleophilic to replace the specific leaving group on the benzoic acid derivative, thereby successfully introducing ethoxy groups.
Furthermore, it is also crucial to construct the complex side chain part of N - {[4 - (4 - fluorobenzyl) -2 - morpholinyl] methyl}. The nucleophilic substitution reaction of 4 - fluorobenzyl halide with 2 - amino - 4 - substituent - morpholine can be carried out first to generate the corresponding N - benzylation product. Subsequently, this product is amidated with a carboxyl-containing compound (such as the active carboxyl derivatives of benzoic acid derivatives prepared earlier, such as acyl chloride, etc.) to form the amide bond structure of the target product.
During the entire preparation process, each step of the reaction requires fine control of the reaction conditions. Temperature, reaction time, molar ratio of reactants, and choice of reaction solvent all have significant effects on the yield and selectivity of the reaction. After each step of the reaction, suitable separation and purification methods, such as column chromatography, recrystallization, etc., should be used to obtain high-purity intermediate products and final target products 4 - Amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) -2 - morpholinyl] methyl} benzamide to ensure that the quality and purity of the product meet the requirements.
4-Amino-5-chloro-2-ethoxy-N- {[4- (4-fluorobenzyl) -2-morpholinyl] methyl} benzamide is safe?
4 - Amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) - 2 - morpholinyl] methyl} benzamide is a complex organic compound. Regarding its safety, we should view it from multiple aspects.
In terms of self-chemical structure, it contains amino groups, chlorine atoms, ethoxy groups, benzamides, and fluorobenzyl groups and morpholine groups. Amino groups have certain nucleophilic properties, but their chemical activity may change in this compound due to the influence of surrounding groups. Although chlorine atoms increase molecular stability, they may also participate in the reaction under specific conditions, or affect the toxicity of the compound. Ethoxy groups contribute to the lipid solubility of molecules, or affect their absorption and distribution in organisms.
At the toxicological level, detailed toxicological studies of this compound are rarely seen. However, similar structural compounds can be compared. Containing benzamides, some of which are potentially cytotoxic or genotoxic. The structure of fluorobenzyl and morpholine groups may affect their ability to bind to targets in organisms, which in turn affects safety. For example, fluorinated compounds sometimes have special biological activities, or cause unknown toxic and side effects.
It is safe in the environment, and its degradation in the environment is unknown. If it is difficult to degrade, it may accumulate in the environment and affect the ecological balance. And its degradation products are also unknown, or have higher toxicity or biological activity.
In summary, due to the lack of data, the safety of 4-Amino-5-chloro-2-ethoxy-N - {[4 - (4 - fluorobenzyl) - 2 - morpholinyl] methyl} benzamide is difficult to determine with certainty. Follow-up toxicological tests are needed to explore its acute and chronic toxicity to organisms, genetic toxicity, etc., and environmental behavior studies, and to clarify its fate and impact in the environment.
4-Amino-5-chloro-2-ethoxy-N- {[4- (4-fluorobenzyl) -2-morpholinyl] methyl} benzamide market prospects?
Today there is 4 - Amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) -2 - morpholinyl] methyl} benzamide, which is a complex organic compound. In today's market environment, there are still many considerations.
Looking at its research and development context, this compound may be derived from the exploration of medical research. In recent years, there is a growing demand for new specific drugs in the pharmaceutical field, and many scientific research teams are dedicated to the discovery of new molecular entities. This compound may be designed for specific disease targets. If it can exhibit excellent pharmacological activity, it may gain a place in the market.
From the perspective of market competition, the current global pharmaceutical research and development is in full swing, and drugs with similar mechanisms of action are either already on the market or in the process of research and development. If this compound wants to stand out, it needs to have unique advantages in terms of efficacy, safety, cost-effectiveness, etc. If its efficacy is excellent, it can solve the shortcomings of existing drugs, and it is safe and has mild side effects, it may be easier to be recognized during marketing activities.
However, production cost is also a key factor. If the production process is complicated and the raw materials are scarce and expensive, it will limit its large-scale production, which will affect the market popularity. Therefore, optimizing the production process and reducing costs can enhance its market competitiveness.
In addition, marketing activities and marketing strategies are also indispensable. It is necessary to accurately locate the target market, understand the needs of doctors and patients, and enhance product awareness and reputation through professional academic promotion and clinical trial results display.
In summary, the market landscape of 4 - Amino - 5 - chloro - 2 - ethoxy - N - {[4 - (4 - fluorobenzyl) -2 - morpholinyl] methyl} benzamide depends on many factors such as research and development results, competitive situation, production costs and marketing activities. If it can be properly managed in all aspects, it may be able to achieve great results in the market.