What is the chemical structure of -4-Amino-5-chloro-2-ethoxy-N- [[4- (4-fluorobenzyl) -2-morpholinyl] methyl] benzamide?

This is the chemical structure of (±) -4-amino-5-chloro-2-ethoxy-N - [[4 - (4 - fluorobenzyl) - 2 - morpholinyl] methyl] benzamide. Its structure is complex and consists of many parts cleverly combined.

Looking at its main body, benzamide is the core structure. Above the benzene ring, there are amino groups at 4 positions, chlorine atoms at 5 positions, and ethoxy groups at 2 positions. This is the layout of benzene ring substituents. The part connected by the N atom is more delicate, and it is [[4- (4-fluorobenzyl) -2-morpholinyl] methyl] structure.

Among them, the morpholine ring has a specific spatial configuration and electronic properties, and the 4-position is connected to 4-fluorobenzyl, and the 4-position on the benzyl ring in the benzyl group has fluorine atom substitution, and is connected to the morpholine ring through methylene, and finally the whole structure is connected to the N atom of benzamide.

The structure of this compound affects each other, and the bonding mode and spatial arrangement between atoms play a key role in its chemical properties, physical properties and biological activities. The uniqueness of its structure, which may endow the compound with specific pharmacological activities or other special properties, is of great value in the study of chemistry and related fields.

(±) What are the main uses of -4-Amino-5-chloro-2-ethoxy-N- [[4- (4-fluorobenzyl) -2-morpholinyl] methyl] benzamide?

(±) - 4 - amino - 5 - chloro - 2 - ethoxy - N - [4 - (4 - fluorobenzyl) - 2 - morpholinyl] methyl] benzamide has a wide range of uses. In the field of medicine, it may be the key raw material for the creation of new drugs. Modern pharmacological research has gradually revealed that it has specific biological activities, or can act on specific targets in the body, and has potential value in the treatment of specific diseases, such as some intractable diseases, and is expected to find new treatment opportunities for patients.

On the road of scientific research and exploration, as an important chemical reagent, it helps researchers to deeply explore the relevant chemical reaction mechanism, clarify the relationship between compound structure and activity, pave the way for subsequent compound design and research and development, and promote the progress of organic chemistry and medicinal chemistry.

Furthermore, at the level of industrial production, if it can achieve large-scale and efficient synthesis, it may become an important intermediate for many chemical products. After further reaction and transformation, more high-value-added products can be derived, expanding the industrial chain, and contributing to the development of the chemical industry. In short, this compound has potential value and application prospects in many fields such as medicine, scientific research, and industry.

What is the synthesis method -4-Amino-5-chloro-2-ethoxy-N- [[4- (4-fluorobenzyl) -2-morpholinyl] methyl] benzamide?

The synthesis of (±) -4-amino-5-chloro-2-ethoxy-N - [4 - (4 - fluorobenzyl) - 2 - morpholinyl] methyl] benzamide is a key research in the field of organic synthesis. This paper imitates the ancient classical text of "Tiangong Kaiwu" and describes its outline.

To obtain this compound, the common way is to first take appropriate starting materials, such as chlorine-containing, ethoxy-containing benzoic acid derivatives, and fluorobenzyl-containing and morpholinyl-containing amine compounds, by amide bonding. This amide bonding requires appropriate reaction conditions. It is often assisted by a condensing agent, such as dicyclohexyl carbodiimide (DCC) or 1- (3-dimethylaminopropyl) -3-ethyl carbodiimide hydrochloride (EDC · HCl). In suitable solvents, such as dichloromethane, N, N-dimethylformamide (DMF), etc., the temperature and reaction time are controlled to make the two condensate to form amide bonds.

Furthermore, the selection of starting materials and pretreatment are quite important. Benzoic acid derivatives containing chlorine and ethoxy groups need to be purified first to remove their impurities and maintain their purity. And amine compounds containing fluorobenzyl and morpholinyl should also be carefully processed to ensure a smooth reaction. In a reaction, the control of temperature is related to the reaction rate and product selectivity. Generally speaking, low temperature can reduce side reactions, high temperature or accelerate the reaction, so it is necessary to find a balance. The length of time also needs to be explored. If it is long, it may cause excessive reaction and damage the quality of the product; if it is short, the reaction is not completed and the yield is not good.

Also, after the reaction is completed, the separation and purification of the product is also a priority. The column chromatography method is often used to select the appropriate stationary phase and mobile phase to separate the product from the impurities to obtain pure (±) -4-amino-5-chloro-2-ethoxy-N - [4 - (4 - fluorobenzyl) - 2 - morpholinyl] methyl] benzamide. During the process, each step requires fine operation and attention to details to make the synthesis smooth and obtain the expected product.

What are the physicochemical properties of -4-Amino-5-chloro-2-ethoxy-N- [[4- (4-fluorobenzyl) -2-morpholinyl] methyl] benzamide?

(±) -4 -Amino-5-chloro-2-ethoxy-N - [4 - (4 - fluorobenzyl) - 2 - morpholinyl] methyl] benzamide, the physical and chemical properties of this substance are quite critical, and are often involved in pharmaceutical and chemical research.

Its properties may be white to off-white crystalline powder, which is caused by the interaction of various groups in its molecular structure. The melting point, boiling point and other characteristics are also closely related to the intermolecular forces. In terms of melting point, the molecules of the compound are maintained by van der Waals forces, hydrogen bonds, etc. At a specific temperature, these forces are overcome, and the substance changes from solid to liquid. The melting point can be accurately measured to obtain specific values. This value is of great significance for purity identification.

In terms of solubility, due to both polar groups in the molecule, such as amino groups, ethoxy groups, etc., and non-polar parts, such as phenyl rings, fluorobenzyl groups, etc., the solubility varies in different solvents. In polar solvents such as water and ethanol, polar groups form hydrogen bonds or other forces with solvent molecules, exhibiting certain solubility; in non-polar solvents such as n-hexane, the solubility is poor. In terms of stability, some chemical bonds in the chemical structure of

, such as amide bonds, may undergo reactions such as hydrolysis under specific conditions. In acidic or alkaline environments, the hydrolysis rate may vary, and the temperature increases, the reaction rate is usually accelerated. However, due to the structural characteristics of conjugated systems in molecules, they have certain stability under general conditions and can maintain structural integrity. The spectral properties of

cannot be ignored. In infrared spectroscopy, the vibration absorption peaks of different chemical bonds can clearly show the characteristics of each group, such as the stretching vibration peak of amino groups and the skeleton vibration peak of benzene rings, etc., so as to confirm the structure of compounds. In nuclear magnetic resonance spectroscopy, hydrogen atoms and carbon atoms in different chemical environments produce specific chemical shifts, which provide key information for molecular structure analysis. These various physical and chemical properties are the cornerstones for the in-depth research and application of this compound.

What is the market outlook for -4-Amino-5-chloro-2-ethoxy-N- [[4- (4-fluorobenzyl) -2-morpholinyl] methyl] benzamide?

(±) -4 -Amino-5-chloro-2-ethoxy-N - [4 - (4 - fluorobenzyl) - 2 - morpholinyl] methyl] benzamide is a promising compound, but its market prospect is influenced by many factors intertwined.

Looking at the field of pharmaceutical research and development, this compound may have unique pharmacological activities. If it is proved to be effective and safe for specific diseases after detailed research and verification, the market prospect should be broad. Take many innovative drugs in the past as an example, such as the advent of artemisinin, which has greatly improved the treatment of malaria and has been highly recognized in the global pharmaceutical market. If (±) -4-amino-5-chloro-2-ethoxy-N - [[4- (4-fluorobenzyl) -2-morpholinyl] methyl] benzamide can also emerge in this regard, with the rigidity of disease treatment demand, it will be able to gain a place in the pharmaceutical market.

However, the road to research and development is full of obstacles. In the pre-clinical research stage, it is necessary to conduct in-depth research on its pharmacodynamics, pharmacokinetics and toxicology, which is a long and expensive process. If the research results do not meet expectations, such as poor efficacy or excessive toxicity, it will be difficult to enter clinical trials, let alone market sales, and the market prospect will be lost.

Even if it successfully passes the R & D hurdle, market competition should not be underestimated. Innovations in the pharmaceutical industry have emerged one after another, and similar or alternative drugs may have occupied market share. If this compound wants to stand out, it needs to have unique advantages in terms of efficacy, safety and price. Just like in the field of anti-cancer drugs, many new drugs compete for the market, and each can do its best to attract doctors and patients with high-quality efficacy and reasonable prices.

Furthermore, regulations and policies have a profound impact on its market prospects. The drug approval process is strict and needs to meet many standards and requirements. If the policy changes, the approval difficulty will increase, the IPO time of the product will be delayed, the cost of the enterprise will increase, and the market opportunity may be delayed.

In summary ，（±） - 4-amino-5-chloro-2-ethoxy-N - [4 - (4 -fluorobenzyl) - 2 -morpholinyl] methyl] benzamide has potential opportunities, but the market prospect is full of variables due to factors such as R & D risks, market competition and regulations and policies. Only by successfully overcoming many obstacles can we shine in the market.