3 Fluorobenzyl Methylamine
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
(3-FLUOROBENZYL)METHYLAMINE
Chemical Formula C8H10FN
Molar Mass 139.17 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 184 - 186 °C
Melting Point N/A
Density 1.032 g/cm³
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 69 °C
Odor Characteristic amine - like odor
Chemical Formula C8H10FN
Molar Mass 139.17 g/mol
Appearance Typically a liquid (physical state can depend on conditions)
Boiling Point Data may vary, specific values depend on purity and pressure
Solubility Soluble in some organic solvents like ethanol, dichloromethane, etc.
Flash Point Data may vary based on testing methods and purity
FAQ

What are the chemical properties of (3-fluorobenzyl) methylamine?

(3-Hydroxyethyl) acetaniline is also an organic compound. Its chemical properties are quite characteristic, let me tell them one by one.

This compound has a certain stability, and can exist more stably at room temperature and pressure. In case of special conditions, it will also show a lively side.

It has a certain solubility and can be well dissolved in some organic solvents, such as ethanol, ether, etc. This property is very important in many chemical operations, such as separation and purification. It can take advantage of its solubility difference to effectively separate.

(3-Hydroxyethyl) acetaniline contains specific functional groups, which is an important factor in determining its chemical properties. The presence of hydroxyl groups and acetamide groups allows the compound to participate in a variety of chemical reactions. Hydroxyl groups are nucleophilic and can react with many electrophilic reagents. For example, they can be acylated with acyl halides, acid anhydrides, etc. to form corresponding ester compounds. This reaction is often used to construct compounds with specific structures in organic synthesis.

Acetamide groups also have unique chemical activities. Under appropriate conditions, hydrolysis reactions can occur to generate corresponding amines and acetic acids. This hydrolysis reaction can sometimes be used as a key step in the field of organic synthesis and drug development to prepare amine compounds with specific structures.

In addition, the chemical properties of (3-hydroxyethyl) acetaniline are also reflected in its participation in some condensation reactions. By condensation with other compounds containing active groups, more complex organic molecular structures can be constructed.

In short, the chemical properties of (3-hydroxyethyl) acetaniline are rich and diverse, and it has important application value in organic synthesis, medicinal chemistry and other fields. By virtue of its chemical properties, the preparation and research and development of various compounds can be carried out.

What are the main uses of (3-fluorobenzyl) methylamine?

(3-Hydroxypropyl) ethyl acetate has many main uses.

In the field of medicine, it is often used as an important organic synthesis intermediate. Taking the preparation of some cardiovascular drugs as an example, (3-hydroxypropyl) ethyl acetate can participate in the construction of key structural fragments of drug molecules. Through a series of chemical reactions, it imparts specific activities and pharmacological properties to the drug, helping the drug to achieve effective treatment of cardiovascular diseases.

In the fragrance industry, its role is also quite significant. Because of its unique chemical structure and physical properties, it can contribute a unique flavor to the preparation of fragrances. It can be cleverly matched with other fragrance ingredients to create a rich and harmonious aroma atmosphere. In the preparation of floral fragrances, (3-hydroxypropyl) ethyl acetate can add layers and freshness to the aroma, making the floral fragrance emitted by the fragrance more realistic and attractive, and improving the quality and attractiveness of fragrance products.

In the coating industry, (3-hydroxypropyl) ethyl acetate plays an important role as an excellent solvent. It has good solubility to various resins and can effectively adjust the viscosity and drying speed of coatings. When preparing high-quality automotive paints, adding an appropriate amount of (3-hydroxypropyl) ethyl acetate can evenly cover the surface of the vehicle during the spraying process, forming a smooth, flat and well-adhered paint film. At the same time, it can speed up the drying speed of the paint film and improve production efficiency.

In the field of organic synthesis, (3-hydroxypropyl) ethyl acetate is a crucial starting material. By reacting with different reagents, a wide variety of organic compounds can be derived. For example, by reacting with compounds containing amino groups, nitrogen-containing organic compounds with specific functions can be constructed, providing a rich material basis and diverse reaction paths for the development of organic synthesis chemistry.

What are the precautions for (3-fluorobenzyl) methylamine during storage and transportation?

When storing and transporting (3-hydroxyethyl) acetyl hydrazide, many key matters need to be paid attention to.

When storing, the temperature and humidity of the environment should be the first priority. It should be placed in a cool and dry place to avoid high temperature and humidity. High temperature can easily cause its chemical properties to change, or cause reactions such as decomposition; humid environment may make it absorb moisture, affecting purity and quality. As "Tiangong Kaiwu" said, the storage of things should go with its own nature and be suitable. The same is true for this substance. The appropriate temperature and humidity are the foundation for storage.

Secondly, it is necessary to pay attention to the isolation of other substances. Because of its specific chemical activity, if it coexists with incompatible substances, or biochemical reactions, it will cause deterioration or danger. For example, acid and alkali substances, in contact with or react violently, must be stored separately and clearly marked to prevent mismixing.

Furthermore, the choice of storage containers is also critical. Containers with good corrosion resistance and sealing properties should be selected, such as glass or specific plastic containers, which can not only prevent them from reacting with the container, but also avoid leakage and ensure safety.

As for transportation, the first guarantee is that the packaging is stable. According to its characteristics, it must be wrapped with suitable cushioning materials to prevent damage due to vibration and collision during transportation.

The environment of the transportation vehicle should also not be ignored. It is also necessary to maintain suitable temperature and humidity and ensure good ventilation to disperse harmful gases that may be generated.

In addition, transport personnel should have professional knowledge and be familiar with the properties of the substance and emergency treatment methods. In case of emergencies, such as leakage, they can respond quickly and properly to minimize harm. In this way, the purpose of safe storage and transportation of (3-hydroxyethyl) acetohydrazide can be achieved, which is in line with the good management of things advocated by Tiangong Kaiwu.

What are the synthesis methods of (3-fluorobenzyl) methylamine?

There are many synthesis methods of (3-hydroxymethyl) acrylate, which are described in detail below.

First, acrylic acid and formaldehyde are used as raw materials and react under the action of a specific catalyst. This reaction requires careful regulation of the reaction conditions. Temperature, pressure and catalyst dosage are all crucial. When the temperature is too high, side reactions occur frequently and the purity of the product decreases; if the temperature is too low, the reaction rate is slow and takes a long time. The choice of catalysts is also exquisite, such as alkali metal salts or organic bases. Different catalysts have a significant impact on the reaction activity and selectivity. During the reaction, formaldehyde and acrylic acid are mixed in a certain proportion. Under the catalysis of the catalyst, the carbonyl group of formaldehyde and the active hydrogen of acrylic acid undergo an addition reaction to gradually generate (3-hydroxymethyl) acrylate.

Second, it can be prepared from methyl methacrylate and paraformaldehyde through a specific reaction path. This process often requires the addition of a phase transfer catalyst to promote the smooth progress of the reaction between different phases. After the depolymerization of paraformaldehyde and methyl methacrylate, a condensation reaction occurs. This reaction process is complicated and the intermediate products are diverse. In order to obtain a high-purity target product, the reaction process needs to be closely monitored and the reaction parameters adjusted in a timely manner. After the reaction is completed, fine separation and purification steps are required to remove unreacted raw materials, by-products and catalyst residues.

Third, acronaldehyde is used as the starting material, and 3-hydroxypropionaldehyde is first synthesized by hydroxylation reaction, and then (3-hydroxymethyl) acrylate is prepared by oxidation, esterification and other series of reactions. The hydroxylation reaction conditions of acronaldehyde are harsh, and the requirements for reaction equipment are quite high. The oxidation process requires the selection of appropriate oxidizing agents and oxidation conditions to prevent excessive oxidation. The esterification reaction needs to pay attention to factors such as the proportion of alkyd and acid, the type of catalyst and the reaction time to ensure that the esterification reaction is fully carried out and the yield of the product is improved.

The above synthesis methods have their own advantages and disadvantages. In practical application, factors such as raw material cost, reaction conditions, product purity and yield need to be considered comprehensively, and careful choices should be made.

What are the effects of (3-fluorobenzyl) methylamine on the environment and human health?

The impact of (3-hydroxyethyl) acetyl on the environment and human health is related to many aspects.

In terms of the environment, if this substance enters the water body, it may interfere with the aquatic ecosystem. Aquatic organisms have different tolerances to it. At low concentrations, it may affect the growth and reproduction of some plankton, causing changes in the biomass at the bottom of the food chain, which in turn affects the stability of the entire aquatic food chain. At high concentrations, it may cause acute toxicity to aquatic animals such as fish, damage their gills, liver and other organs, and reduce their chances of survival. And in the soil, it may adsorb on soil particles, affect the activity and community structure of soil microorganisms, change the material circulation and nutrient transformation process in the soil, affect the absorption of nutrients by plant roots, and indirectly affect vegetation growth.

As far as human health is concerned, inhalation through the respiratory tract or irritation of respiratory mucosa can cause uncomfortable symptoms such as cough and asthma. Long-term exposure may damage the respiratory cilia system, reduce respiratory defense function, and increase the risk of respiratory diseases. Through skin contact, some people may experience allergic reactions, such as skin itching, redness and swelling, because it may enter the human blood circulation through the skin barrier, causing potential harm to the liver, kidneys and other organs, affecting their normal metabolism and detoxification functions. If accidentally ingested, it will stimulate the gastrointestinal tract, causing nausea, vomiting, abdominal pain and other symptoms. In severe cases, it may cause erosion and bleeding of the gastrointestinal mucosa, affecting the normal operation of the digestive system. Long-term low-dose intake may also interfere with the human endocrine system, affect hormone balance, and cause adverse effects on the reproductive system and immune system.