Chemical Formula | C7H5BrClF |
Molar Mass | 225.47 g/mol |
Appearance | Typically a colorless to light - colored liquid |
Boiling Point | Approximately 230 - 240 °C |
Density | Higher than water (approx. 1.7 - 1.8 g/cm³) |
Solubility | Soluble in organic solvents like dichloromethane, chloroform, etc., insoluble in water |
Odor | Pungent, characteristic halogen - containing organic compound odor |
Flash Point | Relatively high, due to its halogenated nature |
Reactivity | Reactive towards nucleophiles due to the presence of bromine and chlorine |
Chemical Formula | C7H5BrClF |
Molar Mass | 223.47 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | Around 225 - 227 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
Hazard Class | Irritant, may cause skin, eye and respiratory irritation; Toxic if ingested or inhaled |
What is the main use of 2-chloro-5-fluorobenzyl bromide?
2-% -5-alkanthiophenyl ether, its main uses are as follows:
In the field of chemical synthesis, this chemical compound is often used as a medium. Due to the presence of chemical atoms and alkanthio groups, molecules with specific chemical reactions and other functional interactions can be formed. For example, in the study of some antibacterial compounds, 2-% -5-alkanthiophenyl ether can be used as a starting material, a series of substitutions, combinations, etc. can be used to introduce other necessary groups, and the most effective antibacterial molecules can be obtained.
In terms of materials science, it can be used to synthesize polymer materials with special properties. The atom in the alloy can increase the resistance and flame retardancy of the material, while the alkyl thiophenyl ether may affect the solubility and processability of the material. For example, in the production of some high-performance engineering plastics, 2-% -5-alkyl thiophenyl ether can be used as a polymerization reaction, which can improve the resistance of plastics, so that it can still maintain good physical properties in high-performance environments, and can be used in the manufacture of automotive parts, aerospace components, and other materials with demanding properties.
In the research, 2-% -5-alkyl thiophenyl ether also plays an important role. It can be used as an important component in the synthesis of new plastics, and its chemical properties can be used to produce compounds with high efficiency, bacteria or herbicidal activities. Reasonable determination of the atoms and alkyl sulfide groups can precisely control the activity and durability of the sulfide, reduce the impact of the sulfide environment, and improve the use effect of sulfide.
What are the physical properties of 2-chloro-5-fluorobenzyl bromide?
2-%-5-methylfurfural is a characteristic compound. Its physical properties are worth exploring.
First of all, it is often a light to amber viscous liquid. The shape of this color is its initial impression. In terms of taste, it has a special aromatic smell, which is not strong and pungent, and has a strong taste. It is like hiding a secret part of the world.
And the boiling temperature, the melting temperature is between 31 and 34 degrees Celsius. At this limit, the solid-liquid temperature quietly melts. The boiling temperature is high, from 203 to 204 degrees Celsius, and high energy is required to vaporize it. This property is an important factor to consider in terms of its preparation, separation, and storage.
The solubility of 2-%-5-methylfurfural is also an important physical property. It is soluble in many kinds of solutions, such as ethanol, acetone, and dimethylmethylformamide. This solubility allows it to be used as a reaction medium or medium medium in many synthetic reactions. However, its solubility in water is limited, and this difference also affects its distribution in different environments.
In terms of density, it is about 1.2 grams per cubic centimeter, and the value determines its position in liquid mixtures. This property cannot be ignored in operations involving multi-phase reactions.
In addition, 2-%-5-methyl furfural has certain properties, which are not as easy to disperse as some low-boiling compounds, but in a specific temperature and force environment, some molecules are also in the liquid phase and enter the liquid phase. This property needs to be properly prevented and controlled in its storage and use scenarios to avoid loss or safety hazards.
Is the chemical property of 2-chloro-5-fluorobenzyl bromide stable?
The chemical properties of 2-%-5-methylfurfural are determined in terms of phase. In the molecule of 2-%-5-methylfurfural, the phase of methylfuran is determined, and this phase is given a certain degree of chemical activity, but under normal conditions, it shows a phase determination.
In terms of qualitative properties, under general conditions, it is not easy to crack or rearrange without a specific high temperature. However, if it is added to a high temperature, such as exceeding its decomposition degree, the chemical properties in the molecule can be affected by energy and crack, leading to a series of reactions, such as water, polymerization, etc.
In terms of chemical activity, its methyl group has a certain degree of nuclear properties, which can be reversed by esterification, etherification, etc. However, this reaction usually needs to be carried out in the presence of specific catalytic conditions, such as low temperature and low temperature. In the normal environment of normal and low temperature catalysis, the reaction rate is slow, or even almost non-existent.
In the acid environment, 2-%-5-methylfurfural also has a certain degree of characterization. In neutral or weakly acidic, weakly acidic conditions, its molecules can remain stable. However, in the acid or low temperature environment, furan and methyl may react, such as hydrolysis, etc., resulting in molecular modification.
In the normal environment, 2-%-5-methylfurfural is stable in normal conditions, such as low temperature and low temperature. However, in the case of high-end components such as high-temperature, high-acid, high-temperature, etc., their chemical properties are changed, leading to different chemical reactions, resulting in molecular and chemical changes.
What are the synthesis methods of 2-chloro-5-fluorobenzyl bromide?
The synthesis method of 2-% cyanogen-5-fluorouracil ester covers the chemical technology and is delicate and complicated. Here are several common methods.
One is the esterification reaction method. Take an appropriate alcohol and place it in a suitable reaction vessel with 2-cyanogen-5-fluorouracil under the catalysis of acid or base. If an acid is used as a catalyst, such as sulfuric acid, p-toluenesulfonic acid, etc., the acid can activate the reaction check point between the alcohol and 2-cyanogen-5-fluorouracil, which prompts the esterification reaction of the two. When reacting, it is necessary to pay attention to the regulation of temperature. If the temperature is too high or side reactions will breed, and if it is too low, the reaction rate will be slow. Generally speaking, the target product 2-cyano- 5-fluorouracil ester can be obtained by controlling the temperature in a moderate range, such as 50-80 degrees Celsius, after several hours or even tens of hours of reaction.
The second acyl chloride method. First, 2-cyano- 5-fluorouracil is converted into the corresponding acid chloride, which is often combined with chlorination reagents such as thionyl chloride. In this process, thionyl chloride reacts with 2-cyanogen-5-fluorouracil, and the hydroxyl group is replaced by a chlorine atom to form an acid chloride. Then the obtained acid chloride reacts with alcohols in an alkaline environment. The base can neutralize the hydrogen chloride generated by the reaction and promote the reaction forward. Commonly used bases such as pyridine and triethylamine have relatively mild reaction conditions. At room temperature or slightly higher temperatures, 2-cyanogen-5-fluorouracil esters can be efficiently synthesized.
The third is the transesterification method. Using the existing ester derivatives of 2-cyanogen-5-fluorouracil as raw materials, the transesterification reaction is carried out with another alcohol under the action of a catalyst. The catalyst can be selected from metal alkoxides, etc., which can effectively promote the exchange of ester groups. During the reaction, the temperature and reaction time are adjusted according to the selected raw materials and catalyst characteristics. Usually under the condition of heating and reflux, the pure 2-cyanogen-5-fluorouracil ester can be obtained through separation and purification during the reaction.
All synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively consider the availability of raw materials, cost, product purity and many other factors, and make careful choices in order to achieve efficient and economical synthesis goals.
What should be paid attention to when storing and transporting 2-chloro-5-fluorobenzyl bromide?
2-%-5-pentaminosulfonic acid should be paid attention to the following things:
First, the degree of control is of paramount importance. The degree of this substance is sensitive, and high temperature may cause its chemical properties to change, or cause decomposition and other adverse effects. Therefore, it is recommended to keep it cool and transparent, and avoid direct sunlight to prevent high temperature. Generally speaking, the degree of storage should be maintained between 5 ° C and 30 ° C, so as to ensure its stability. On the way, it is also necessary to pay attention to the shadow of the outside world. If it is hot summer, or take measures to reduce the temperature, such as using refrigeration, etc., to improve its quality.
Second, moisture-proof should not be ignored. 2-%-5-pentaminosulfonic acid has absorbency, and it is easy to be damaged in case of moisture, which will affect its use efficiency. The storage container should be well sealed, and the storage place should be dry. During the period, it is also necessary to ensure that the tool is tight to prevent rainwater from invading. If it is accidentally damp, it will be treated quickly. For example, the method of low dryness should be used to restore the dryness, and then be careful not to change its properties due to the dryness of the dryness.
Third, to avoid the connection of incompatible substances. This compound may cause strong reactions such as certain acids, oxides, etc. If it is stored, it must not be placed in the same place, and it should be stored separately, and the distance should be kept. In the process, it is also necessary to mix the incompatible substances to prevent accidents. In case of unknown chemical products, it is necessary to check their properties first, and determine whether the reaction of 2-%-5-pentaminosulfonic acid can be determined before the method can be determined.
Fourth, the package must be solid. If it is not stored or damaged, a good package can effectively protect the package. The package material has a certain degree of accuracy, which can resist external forces and prevent the package from being damaged and causing the package to leak. At the same time, the package clearly indicates its name, sex, danger warning, etc., so that the other party can take care of it.