Chemical Formula | C7H5Br2F |
Molar Mass | 270.92 g/mol |
Appearance | Solid |
Color | White to off - white |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
Boiling Point | Approximately 270 - 275 °C |
Melting Point | 68 - 72 °C |
Purity Typical | 97%+ (high - purity grade available) |
Odor | Pungent |
Name | 2-Bromo-5-fluorobenzyl bromide |
Molecular Formula | C7H5Br2F |
Molecular Weight | 269.92 |
Appearance | Off-white to light yellow solid or liquid |
Boiling Point | 234 - 236 °C |
Melting Point | 35 - 39 °C |
Density | 1.948 g/cm³ |
Solubility | Insoluble in water, soluble in organic solvents like ethanol, ether |
Flash Point | 101.3 °C |
Refractive Index | 1.583 (20 °C) |
What are the chemical properties of 2-bromo-5-fluorobenzyl bromide?
2-% -5-methylfurfural is a chemical substance with general characteristics. Its properties are important in the chemical field and can be multi-terminal.
First of all, its physical properties are important. This compound is often in a specific shape, or in solid crystals, or in the shape of a powder. The color or depth varies according to its degree and temperature. Its melting and boiling also have specific values, which are determined by the molecular force and the characteristics of the product. For example, due to the molecular force and Vander force, some 2-%-5-methylfural has a high melting phase and requires a specific degree of melting.
In addition, the presence of methyl and furfural groups in 2-% -5-methyl furfural makes it reactive. Methyl can be esterified and reacted with acid to form the ester compound of the phase. This reaction often requires the help of catalysis, such as sulfuric acid, etc., and can be carried out under the appropriate degree and reaction.
The furfural group makes the compound have a certain degree of originality. It can be used to react to some oxidizing substances, such as Torres, etc., to generate oxidation reactivity, and the furfural group is oxidized to form the oxide of the phase.
In addition, 2-%-5-methylfurfural can also be substituted by nuclear substitution, because some atoms or groups in the molecule can be used as nuclear centers to generate new compounds.
And because of its high content, it can be generated in aqueous solution, showing a certain acidity. This property also affects its reaction and reaction in solution. It can be used in the production of acid substances, such as neutralization, etc., and its chemical properties can be changed. In particular, 2-%-5-methylfural has important applications and research values in chemical synthesis, materials, and other fields due to its chemical properties.
What are the common synthesis methods of 2-bromo-5-fluorobenzyl bromide?
2-% hydroxyl-5-aldehyde benzoic acid, often prepared by chemical synthesis. The following are common synthesis routes:
###With toluene derivatives as starting materials
1. ** Nitration reaction **:
- With p-toluic acid as the starting material, under the catalysis of concentrated sulfuric acid, nitrification occurs with concentrated nitric acid. During this process, nitric acid attacks the benzene ring as an electrophilic reagent to generate 4-methyl-3-nitrobenzoic acid. < Br > - Reaction formula: p-toluic acid +\ (HNO_3\) (concentrated) \ (\ xrightarrow [] {H_2SO_4}\) 4-methyl-3-nitrobenzoic acid +\ (H_2O\)
2. ** Oxidation reaction **:
- The above product is oxidized with a suitable oxidizing agent, such as an acidic solution of potassium permanganate or potassium dichromate, and the methyl group is oxidized to an aldehyde group to give 5-aldehyde-2-nitrobenzoic acid. < Br > - Reaction formula: 4-methyl-3-nitrobenzoic acid +\ (oxidizing agent\) \ (\ xrightarrow [] {acidic conditions}\) 5-aldehyde-2-nitrobenzoic acid
3. ** Reduction reaction **:
- Using metals (such as iron, zinc) with hydrochloric acid, or catalytic hydrogenation, the nitro group is reduced to a hydroxyl group, and finally 2-hydroxyl-5-aldehyde benzoic acid is obtained. < Br > - Taking iron and hydrochloric acid as an example, the reaction formula: 5-aldehyde-2-nitrobenzoic acid +\ (Fe + HCl\) \ (\ longrightarrow\) 2-hydroxyl-5-aldehyde benzoic acid + ferric salt and other by-products
###Take benzoic acid derivatives as starting materials
1. ** Halogenation reaction **:
- With benzoic acid as starting material, under the action of light or initiator, it undergoes side chain halogenation with halogens (such as bromine) to generate halogenated benzoic acid, such as 2-halogenated benzoic acid. < Br > - Reaction formula: benzoic acid +\ (Br_2\) \ (\ xrightarrow [] {light or initiator}\) 2-bromobenzoic acid +\ (HBr\)
2. ** Formalylation reaction **:
-2-halobenzoic acid is formylated with suitable reagents (such as carbon monoxide, aluminum chloride and cuprous chloride systems), and an aldehyde group is introduced at a specific position in the benzene ring to give 2-halo-5-aldehyde benzoic acid. < Br > - Reaction formula: 2-bromobenzoic acid +\ (CO + reagent\) \ (\ xrightarrow [] {catalyst}\) 2-bromo-5-aldehyde benzoic acid
3. ** Hydroxylation reaction **:
- Through nucleophilic substitution reaction, the halogen atom is replaced with a hydroxyl group to obtain the target product 2-hydroxy- 5-aldehyde benzoic acid. The basic aqueous solution can be reacted with the halogen and then acidified. < Br > - Reaction formula: 2 -bromo-5 -aldehyde benzoic acid +\ (OH ^-\) \(\ long right arrow\) 2 -hydroxy- 5 -aldehyde benzoic acid (final product after acidification)
What are the main applications of 2-bromo-5-fluorobenzyl bromide?
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What are the precautions for storing and transporting 2-bromo-5-fluorobenzyl bromide?
For 2-% ether-5-alkyl ether, there are things to pay attention to when hiding and transporting.
When hiding, the first environment is heavy. It should be cool and dry, protected from direct sunlight. If exposed to the sun, ether is easily heated and causes its properties to change, or it is dangerous. And it should be far away from fire and heat sources. Many ethers are flammable, and they will burn in case of fire, or even explode, endangering the surroundings. In addition, it is better to hide in good air to prevent ether gas from accumulating and causing the concentration to exceed the safe limit.
When transporting, make sure to choose an adapter. The device used must be strong and dense to prevent ether leakage. If there is a leak, the ether gas will disperse outside, which will damage its quality on the one hand, and be harmful to the environment and people on the other. When handling, when handling it lightly, do not let the device be shocked or collided to prevent it from breaking and ether leakage. And the operator should know its nature and know the emergency method. If there is a leak or other reasons, it can be dealt with quickly to avoid disaster.
In addition, in the process of hiding and transportation, there should be a detailed record. Remember the number, hiding place, transportation time, etc., so that you can observe and manage it. In this way, you can keep the 2-ether-5-alkyl ether safe and stable during transportation in Tibet, without worry.
What are the effects of 2-bromo-5-fluorobenzyl bromide on the environment and human health?
2-% E6% BA% B4 - 5-%E6%B0%9F%E8%8B%84%E5%9F%BA%E6%BA%B4%E8%80%85, which is produced by the process, contains a lot of harmful substances, which have a great impact on the environment and human health.
In terms of the environment, if the liquid is not properly treated and flows into the natural water, its harmful components, such as heavy gold, toxic substances, etc., pollute the water source. Causing aquatic organisms to survive in the environment, breaking the balance of aquatic life, or causing a large number of aquatic organisms to die and waste. And it enters the soil, changing the physical and chemical properties of the soil, breaking the soil, reducing soil fertility, affecting plant growth, causing vegetation damage and land scarcity. In addition, some harmful substances are added to the environment, forming large pollutants, and bad weather such as acid rain may also be born as a result, adding to the destruction of the environment.
When it comes to human health, if a person consumes contaminated water sources, or eats crops or water products that have absorbed pollutants, harmful substances will accumulate in the person. Such substances may harm important organs such as the liver and body, and affect the normal physiological function of the person. Or it may cause serious diseases such as cancer, which will endanger life safety. If exposed to the environment contaminated by this liquid, skin contact, breathing and inhalation, etc., will cause people to suffer from health problems and increase the risk of various diseases.
Therefore, 2-% E6% BA% B4 - 5-%E6%B0%9F%E8%8B%84%E5%9F%BA%E6%BA%B4%E7%9A%84 is very important to properly manage, and it is necessary to use appropriate means to prevent harm to their environment and human health.