Chemical Formula | C13H12FN3O2 |
Molecular Weight | 261.252 |
Iupac Name | 2 - amino - 5 - [(4 - fluorobenzyl)amino] - 1 - nitrobenzene |
Appearance | Solid (predicted) |
Melting Point | No data available |
Boiling Point | No data available |
Density | No data available |
Solubility In Water | No data available |
Flash Point | No data available |
Vapor Pressure | No data available |
Chemical Formula | C13H12FN3O2 |
Molecular Weight | 261.252 g/mol |
Appearance | Typically a solid (description may vary based on purity and synthesis method) |
Physical State At Room Temperature | Solid |
Melting Point | Data may vary, needs experimental determination |
Boiling Point | Data may vary, needs experimental determination |
Solubility In Water | Expected to be low due to non - polar aromatic groups |
Solubility In Organic Solvents | May be soluble in common organic solvents like dichloromethane, chloroform |
Density | Data may vary, needs experimental determination |
Pka | Data may vary depending on the acidic or basic functional groups' environment, needs experimental determination |
Stability | Can be affected by light, heat, and oxidizing agents |
Odor | Likely to have a faint, characteristic odor |
What are the chemical properties of 2-Amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene
2-Amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene, this is an organic compound. Looking at its structure, amino, nitro and fluorobenzyl amino groups endow it with unique chemical properties.
First of all, solubility, because it contains polar groups, it may have a certain solubility in polar solvents such as ethanol and acetone. However, the existence of nitro groups may cause its solubility to be non-excellent.
When it comes to stability, nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, causing this compound to be more reactive. In case of heat, light or specific chemical reagents, it may react.
Let's talk about the reactivity again. The amino group is the power supply group, which can increase the density of the electron cloud of the benzene ring ortho and para-position, and is prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Although the nitro group is an electron-withdrawing group, it can be reduced under specific conditions, such as iron and hydrochloric acid as reducing agents, which can be converted into an amino group. The amino part of fluorobenzyl, due to the large electronegativity of fluorine atoms, can affect the electron cloud distribution of the atoms connected to it, or show special activity in some reactions.
In addition, this compound may have potential application value in the fields of medicine and pesticides because it contains multiple special groups or has certain physiological activities. However, its specific properties and applications still need more experimental exploration and theoretical calculations to be detailed.
What are the main uses of 2-Amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene
2-Amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene, this substance has a wide range of uses. In the field of pharmaceutical synthesis, it is often used as a key intermediate to help create new drugs. Due to its specific chemical structure, it can interact with many targets in organisms, providing a cornerstone for the development of antibacterial, anticancer, antiviral and other drugs. After subsequent reaction modification, it can accurately meet the needs of drug action.
In the field of materials science, it also has important functions. It can participate in the synthesis of functional polymer materials, giving materials unique optical and electrical properties. For example, by polymerizing with other monomers, optoelectronic materials can be prepared for use in organic Light Emitting Diodes (OLEDs), solar cells, and other devices, which are expected to improve their performance and efficiency.
In the dye industry, it is also indispensable. Its special structure can cause molecules to absorb specific wavelengths of light. After rational design and synthesis, it can become a high-performance dye for use in the textile, printing and dyeing industries, giving fabrics rich colors and good color fastness.
In addition, in the field of scientific research, as an important raw material for organic synthesis, it is used by researchers to explore new reaction paths, expand organic synthesis methodologies, and help in-depth understanding of the properties and reaction laws of organic compounds, promoting the development of organic chemistry. In conclusion, 2-amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene plays an important role in many fields.
What is the synthesis method of 2-Amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene
The synthesis method of 2-amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene is an important topic in the field of organic synthesis. The synthesis method may follow the following path.
First, the nitro group can be introduced by nitrification reaction from suitable starting materials. Select a suitable nitrification reagent, such as a mixed acid of nitric acid and sulfuric acid, and under appropriate reaction conditions, introduce the nitro group at a specific location in the raw material molecule, which is a key step in constructing the target molecular framework.
Then, for the introduction of amino groups, the reduction reaction can be used. If the starting material contains suitable nitro groups or other reducible functional groups, with suitable reducing agents, such as iron and hydrochloric acid system, hydrogen and catalyst system, etc., the nitro and other functional groups are reduced to amino groups. This step requires fine control of the reaction conditions to ensure reaction selectivity and yield.
As for the access of (4-fluorobenzyl) amino groups, or by nucleophilic substitution reaction. The amino-containing intermediate is reacted with 4-fluorobenzyl halide under basic conditions. The base can promote the nucleophilicity of the amino group, so that the amino group attacks the halogen atom of 4-fluorobenzyl halide to connect to the carbon, and completes the introduction of the (4-fluorobenzyl) amino group.
Each step of the reaction requires attention to the control of the reaction conditions, such as temperature, reaction time, and the proportion of reactants. If the temperature is too high or the side reactions increase, the yield will decrease; if the time is too short, the reaction will not be fully functional. The proportion of reactants is also crucial, and the appropriate ratio can make the reaction proceed in the direction of generating the target product. And after each step of the reaction, the pure intermediate or target product should be obtained by suitable separation and purification means, such as column chromatography, recrystallization, etc., to lay a good foundation for the subsequent reaction. In this way, the effective synthesis of 2-amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene may be achieved.
What to pay attention to when storing and transporting 2-Amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene
2-Amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene is an organic compound. When storing and transporting it, careful attention should be paid to many key points.
First environmental conditions. This compound is sensitive to temperature and humidity, and should be stored in a cool, dry and well-ventilated place. If the temperature and humidity are too high, it may cause its chemical properties to change, resulting in damage to the quality. For example, if the temperature is too high, it may accelerate its decomposition process; if the humidity is too high, it may absorb moisture and affect the purity.
Times and packaging materials. Suitable packaging should be selected to prevent leakage and deterioration. It is recommended to use containers with good sealing performance, such as glass bottles or special plastic containers. Glass bottles are chemically stable and can effectively resist corrosion; special plastic containers also need to have good barrier properties to avoid external factors. Warning labels should also be clearly marked on the outside of the package, indicating its characteristics and precautions.
Furthermore, avoid contact with contraindicated substances. 2-Amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene or react violently with certain substances, such as strong oxidizing agents, strong acids and alkalis. When storing and transporting, be sure to keep them isolated from these contraindicated substances to prevent dangerous chemical reactions, such as combustion and explosion.
The transportation process should not be ignored. It is necessary to ensure that the means of transportation are clean, dry and free of residual impurities. During transportation, it should be driven smoothly to avoid violent vibration and collision to prevent packaging damage. At the same time, transportation personnel should be familiar with the characteristics of the compound and emergency treatment methods, and can respond quickly and properly in case of emergencies.
In summary, when storing and transporting 2-amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene, from the environment, packaging, taboo isolation to transportation, all need to be carefully considered and handled to ensure its safety and stability.
What is the market outlook for 2-Amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene?
Today, there are 2-amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene, and its market prospects are related to many aspects.
Looking at this compound, from the perspective of the field of medicine, it may have unique pharmacological activities. In the past, many new drug research and development began with compounds with specific structures. After in-depth investigation, it was found that its effect on specific disease targets. If 2-amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene can be used in pharmacological research to demonstrate the potential efficacy of certain diseases such as tumors and nervous system diseases, it will surely attract the attention of pharmaceutical companies. Pharmaceutical companies will invest resources to deeply study its mechanism of action and pharmacokinetic properties in order to develop finished drugs, which will open up broad prospects for them in the pharmaceutical market.
In the field of materials science, fluorinated compounds often have unique physical and chemical properties. The presence of fluorine atoms in 2-amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene may endow materials with special optical and electrical properties. For example, in the field of optoelectronic materials, new compounds can be used as key materials for the manufacture of high-performance Light Emitting Diodes, solar cells, etc. If this compound can meet the performance requirements of related materials after research, it will also have a place in the materials market.
However, there are also challenges in its market expansion. The complexity and cost of the synthesis process are key factors. If the synthesis route is lengthy and the conditions are harsh, resulting in high production costs, it must limit its large-scale production and application. Furthermore, safety and environmental impact need to be considered. For medical applications, strict safety assessment is essential; for material applications, the environmental impact of its production and use process also needs to be paid attention to. If these two are not properly addressed, it may hinder its marketing activities.
In summary, 2-amino-5- [ (4-fluorobenzyl) amino] -1-nitrobenzene has an addressable market opportunity, but it is necessary to overcome the problems of synthesis cost, safety and environmental protection in order to bloom in the market.