Chemical Formula | C7H5BrF2 |
Molar Mass | 207.015 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 186 - 188 °C |
Melting Point | N/A |
Density | 1.614 g/cm³ |
Flash Point | 75 °C |
Solubility | Insoluble in water, soluble in organic solvents like ethanol, ether |
Refractive Index | 1.503 (20 °C) |
Purity | Typically available in high purity, e.g., 98%+ |
Chemical Formula | C7H5BrF2 |
Molar Mass | 207.015 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 187 - 189 °C |
Density | 1.642 g/mL at 25 °C |
Flash Point | 76 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Pungency | Irritating odor |
Cas Number | 1777-82-8 |
What are the main uses of 2,6-difluorobenzyl bromide?
2% 2C6 -diethylaminofluorescein, often referred to as diethylaminofluorescein, has a wide range of main uses.
In the field of fluorescence analysis, this is a key fluorescent reagent. Because of its special chemical structure, it can fluoresce under specific conditions. In biomedical research, biomolecules such as proteins and nucleic acids can be labeled. With the help of fluorescence properties, researchers can track the behavior, distribution and interaction of these biomolecules in living organisms, helping to delve deeper into physiological and pathological processes in living organisms. For example, in cell biology experiments, diethylaminofluorescein is labeled to a specific antibody, which is combined with the target cell surface antigen, and the distribution and state of cells can be clearly observed with the help of fluorescence microscopy.
Diethylaminofluorescein also plays an important role in environmental monitoring. It can be used to detect certain substances in the environment, such as metal ions. When it reacts with specific metal ions, its fluorescence intensity or fluorescence spectrum will change, thus enabling accurate determination of metal ion content in environmental samples, providing key data support for environmental protection and pollution control.
In addition, in analytical chemistry experiments, diethylaminofluorescein can be used as an indicator. In some chemical reaction systems, as the reaction process progresses and the chemical environment of the system changes, diethylaminofluorescein will exhibit different fluorescence characteristics due to environmental changes, thus indicating the end point of the reaction and helping the experimenter accurately control the reaction process. In conclusion, 2% 2C6-diethylaminofluorescein has indispensable uses in many fields due to its unique fluorescence properties, providing important technical means and tools for scientific research, environmental monitoring, and analytical chemistry.
What are the physical properties of 2,6-difluorobenzyl bromide?
2% 2C6-diethylaminofluorescein is a very important organic compound. Its physical properties are as follows:
Looking at its appearance, under room temperature and pressure, it often shows a yellow to orange crystalline powder, which is easy to store and use.
When it comes to solubility, it shows good solubility in organic solvents, such as ethanol and acetone. This property makes it easy to integrate it into a specific solution system in many chemical experiments and industrial applications to achieve the corresponding reaction or function. However, in water, its solubility is relatively limited, which also determines that its application scenarios are mostly related to organic solvents.
Melting point is also one of its key physical properties, about 116-118 ° C. The exact value of the melting point provides an accurate temperature reference for its physical state transformation during heating. When the temperature rises near the melting point, 2% 2C6-diethylaminofluorescein will gradually melt from a solid state to a liquid state. This property is of crucial significance in the purification, identification and processing of substances under specific conditions.
It has unique absorption and emission characteristics in the visible spectral region. Under the irradiation of light of a specific wavelength, it emits strong fluorescence. This fluorescence property makes it have a wide range of application prospects in many fields, such as fluorescence analysis, biological imaging, etc. With the absorption and emission of specific light rays, accurate detection and tracking of substances can be achieved, providing a powerful tool for scientific research and related industrial development.
Is the chemical property of 2,6-difluorobenzyl bromide stable?
2% 2C6 -diethylaminofluorescein, the chemical properties of this substance are relatively stable. In its molecular structure, specific atomic combinations and chemical bonds endow it with certain stability. The existence of ethylamino groups affects the electron cloud distribution of the molecule as a whole through electronic effects, etc., making the structure tend to be stable.
From the perspective of fluorescence characteristics, a stable chemical structure contributes to the stable development of fluorescence properties. Under common environmental conditions, it is not prone to significant structural changes or decomposition due to external factors, such as ordinary light, moderate temperature changes, general humidity fluctuations, etc.
However, under extreme conditions, such as high temperature flames, strong acids and alkalis, its chemical bonds may be destroyed and its stability will be lost. However, in the conventional experimental operating environment and storage conditions, such as room temperature, dry and free of strong oxidants and other adverse factors, 2% 2C6-diethylaminofluorescein can maintain the stability of its chemical structure and properties for a long time, so it can be applied more stably in related fields such as fluorescent labeling and detection, providing a reliable material basis for scientific research and practical applications.
What are the synthesis methods of 2,6-difluorobenzyl bromide?
2% 2C6-diethylaminoethylamine, which can be synthesized by various methods. The following are described below:
First, 2-chloroethanol is used as the starting material. Shilling 2-chloroethanol reacts with ethylamine. This step needs to be carried out in an appropriate temperature and solvent to obtain 2-ethylaminoethyl ethanol. Then 2-ethylaminoethanol interacts with sulfoxide chloride to convert the hydroxyl group into a chlorine atom to generate 2-chloro-N-ethylamine. Finally, 2-chloro-N-ethylamine reacts with ethylamine and undergoes nucleophilic substitution to obtain 2% 2C6-diethylaminoethylamine. The raw materials of this route are more common, but the steps are slightly complicated, and the reaction conditions of each step need to be precisely controlled.
Second, ethylene oxide is used as the starting material. Under the action of the catalyst, ethylene oxide and ethylamine are added to generate 2-ethylaminoethanol. The subsequent steps are similar to those using 2-chloroethanol as the raw material, that is, chlorination and nucleophilic substitution with ethylamine to obtain the target product. Ethylene oxide has high activity and is relatively easy to occur, but ethylene oxide has certain risks, and special caution is required during operation.
Third, ethanolamine can be considered as the raw material. Ethanolamine first reacts with ethylamine under suitable conditions to generate N-ethylethanolamine. N-ethylethanolamine can also obtain 2% 2C6-diethylaminoethylamine through dehydration and addition to ethylamine. Although this method is simple in raw materials, the dehydration and addition steps require harsh reaction conditions. Appropriate catalysts, reaction temperature, pressure and other conditions need to be selected to ensure the smooth progress of the reaction and the purity of the product.
The above synthesis methods have their own advantages and disadvantages. In practical applications, the appropriate synthesis path needs to be carefully selected according to many factors such as raw material availability, cost, and product purity requirements.
What are the precautions for storing and transporting 2,6-difluorobenzyl bromide?
When storing and transporting 2% 2C6-diethylaminofluorescein, it is necessary to pay attention to many matters. This is a fine chemical substance with unique properties, and a little carelessness may affect its quality and effectiveness.
When storing, the first ambient temperature. It should be placed in a cool place to avoid hot topics. If the temperature is too high, it may cause its chemical structure to change, resulting in performance degradation. The ideal temperature should be controlled at 2-8 ° C. This temperature range can keep its chemical properties relatively stable and prolong the storage period.
Humidity is also the key. It is necessary to prevent humid environment, because it is easy to cause deterioration due to moisture. It should be stored in a dry place, and desiccant can be supplemented to maintain the dry storage space.
Avoidance from light is also indispensable. 2% 2C6-diethylaminofluorescein is sensitive to light, and light will promote photochemical reactions and damage its quality. Therefore, it should be stored in brown bottles or shaded containers, away from direct light.
When transporting, the packaging must be stable. This material is fragile and special in nature, and it is easily damaged by vibration or collision during transportation. It needs to be wrapped in soft cushioning materials, such as foam, cotton, etc., to ensure stability during transportation.
Temperature control during transportation cannot be ignored. If the transportation distance is long, it can be transported by cold chain to keep it in a suitable temperature range.
In addition, transportation and storage must strictly follow relevant regulations and standards. Because it may belong to the category of hazardous chemicals, illegal operation is prone to brewing safety accidents and legal risks. Only by paying attention to the above can we ensure that 2% 2C6-diethylaminofluorescein is of good quality during storage and transportation for subsequent use.