Chemical Formula | C7H6F2O |
Molecular Weight | 144.12 |
Appearance | Colorless to light yellow liquid |
Boiling Point | 188 - 190 °C |
Melting Point | N/A |
Density | 1.234 g/cm³ (at 20 °C) |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in common organic solvents |
Flash Point | 76 °C |
Vapor Pressure | N/A |
Refractive Index | 1.487 - 1.491 (at 20 °C) |
Chemical Formula | C7H6F2O |
Molar Mass | 144.12 g/mol |
Appearance | Colorless liquid |
Odor | Characteristic odor |
Density | 1.233 g/cm³ |
Boiling Point | 187 - 189 °C |
Melting Point | N/A |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in many organic solvents |
Flash Point | 80 °C |
Refractive Index | 1.493 |
What are the main uses of 2,6-difluorobenzyl alcohol?
2% 2C6-diethylaminoethylamine, that is, N, N-diethylethylenediamine, is widely used. In the field of medicine, it is an important raw material for drug synthesis. For example, in the preparation of many antihistamine drugs, it plays a key role in the construction of drug active structures, helps drugs exert anti-allergic effects, and effectively relieves allergic symptoms through specific chemical mechanisms.
In the dye industry, 2% 2C6-diethylaminoethylamine is also indispensable. It can be used as an intermediate to participate in dye synthesis. By reacting with other compounds, it imparts specific colors and properties to dyes, meeting the needs of different colors and fastness dyes in textile, printing and dyeing industries.
Furthermore, in the field of organic synthesis, it can act as an organic synthesis reagent. By virtue of its own chemical activity, it participates in a variety of organic reactions, such as nucleophilic substitution, addition, etc., to realize the construction of complex organic compounds, providing a material basis for the research and development of new materials and the preparation of fine chemicals.
In addition, in terms of rubber additives, 2% 2C6-diethylaminoethylamine can be used to synthesize some rubber accelerators. Such accelerators can accelerate the vulcanization rate of rubber and improve the physical and mechanical properties of rubber products, such as tensile strength and wear resistance, so as to optimize the rubber processing process and product quality.
In summary, 2% 2C6-diethylaminoethylamine has important uses in many fields such as medicine, dyes, organic synthesis and rubber additives, and is of great significance to promoting the development of related industries.
What are the physical properties of 2,6-difluorobenzyl alcohol?
2% 2C6-diethylnaphthoquinone is one of the organic compounds. Its physical properties are particularly important, related to its use and characteristics.
Looking at its properties, at room temperature, 2% 2C6-diethylnaphthoquinone is often in the shape of a solid state, or a crystalline shape, with a glossy appearance, or a light yellow to light brown color, which varies from its purity and crystalline morphology.
When it comes to the melting point, it is about a certain range. This melting point value is very critical when identifying and purifying this substance, and can provide a reference for the experimenter's purity. If the melting point is deviated, it may indicate that impurities are mixed in.
The boiling point is also an important physical property. Under specific pressure conditions, at this temperature, 2% 2C6-diethylnaphthoquinone will change from liquid to gaseous. This property is indispensable in separation, distillation and other process operations. It can help craftsmen extract pure 2% 2C6-diethylnaphthoquinone from the mixture according to its boiling point difference.
In terms of solubility, 2% 2C6-diethylnaphthoquinone may have a certain solubility in organic solvents such as ethanol and ether, but in water, the solubility is very small. This solubility characteristic is of great significance in the selection of media for chemical reactions, product separation and purification steps. For example, after the synthesis reaction is completed, the product can be separated from the reaction system by extraction based on the difference in solubility of different solvents.
Density is also one of its physical properties. Although this value is not often eye-catching, it cannot be ignored in specific industrial production or experimental scenarios, related to the measurement and mixing ratio of materials. Accurately knowing its density can make the operation more accurate and ensure the reliability of product quality and experimental results.
In addition, 2% 2C6-diethylnaphthoquinone may have a certain degree of volatility. Although the degree of volatility may not be high, it should also be paid attention to when storing and using it to prevent its loss due to volatilization, or affect the environment and personal safety. In short, these many physical properties are the key factors in the process of research, production and application of 2% 2C6-diethylnaphthoquinone, which cannot be ignored.
What are the chemical properties of 2,6-difluorobenzyl alcohol?
2% 2C6-diethylnaphthoquinone is one of the organic compounds. It has unique chemical characteristics and often plays an important role in various chemical reactions and industrial processes.
Looking at its chemical structure, the nucleus of naphthoquinone has ethyl groups at two and six positions. This special structure gives it different properties. In terms of its physical properties, it is often solid, with specific melting points and boiling points, and can exhibit different solubility in specific solvents.
In terms of chemical activity, its conjugated system of naphthoquinone structure gives it a certain redox activity. Under appropriate conditions, it can participate in redox reactions and act as an oxidizing agent or reducing agent. The carbonyl group in the structure of naphthoquinone is also electrophilic and can react with many nucleophiles, such as nucleophilic addition reactions. This is an important reaction path for constructing more complex organic molecular structures.
Furthermore, the introduction of ethyl affects the electron cloud distribution and spatial steric resistance of the molecule. The synergistic effect of electronic effect and steric resistance is reflected in the selectivity and activity of the reaction. For example, in some electrophilic substitution reactions, the electron-giving effect of ethyl can affect the activity of the reaction check point, making the reaction more inclined to a specific location.
In addition, 2% 2C6-diethylnaphthoquinone is gradually showing its value in the fields of materials science and medicinal chemistry. In the field of materials, due to its redox activity, it can be applied to the research and development of battery materials or sensor materials; in the field of medicinal chemistry, its unique structure may be used as a lead compound, which can be modified and optimized to explore new drugs with biological activity.
In conclusion, 2% 2C6-diethylnaphthoquinone exhibits a variety of chemical properties due to its unique chemical structure, and has broad application potential in many scientific fields.
What are the synthesis methods of 2,6-difluorobenzyl alcohol?
2% 2C6-diethylnaphthoquinone is an important intermediate in organic synthesis. There are many methods for its synthesis. The following are common methods:
** 1, Foucault acylation reaction **
This is the classic synthesis path. Using naphthalene as the starting material, under the catalysis of Lewis acid (such as aluminum trichloride), Foucault acylation reaction with 2-chloroacetoacetate ethyl ester can be obtained 2 - (2-ethoxycarbonyl acetyl) naphthalene. Subsequent hydrolysis and decarboxylation, then 2-acetylnaphthalene is obtained. Then 2-acetylnaphthalene is alkylated with bromoethane under basic conditions, and ethyl is introduced to form 2-ethyl-6-acetylnaphthalene. Finally, the acetyl group is oxidized to quinone by oxidation steps, such as using an oxidant such as chromic acid, to obtain 2% 2C6-diethylnaphthalene quinone. In this process, the conditions of the Foucault acylation reaction are quite critical, and the reaction temperature, the proportion of reactants and the amount of catalyst need to be strictly controlled to improve the yield and selectivity of the target product.
** II. Palladium-catalyzed coupling reaction **
Naphthalene derivatives containing specific substituents, such as 2-halonaphthoquinone, are first prepared. The halogenated naphthoquinone is used with vinyl borate or vinyl halide as raw materials, and the palladium-catalyzed coupling reaction is carried out in the presence of a palladium catalyst (such as tetra (triphenylphosphine) palladium) and a base (such as potassium carbonate) to form a carbon-carbon bond and introduce vinyl. The vinyl is then hydrogenated to obtain 2-ethyl-6-halonaphthoquinone. Then halogenated naphthoquinone is cross-coupled with an organozinc reagent (such as ethyl zinc reagent), a second ethyl group is introduced, and finally 2% 2C6-diethylnaphthoquinone is synthesized. This method relies on a high-efficiency palladium catalyst, and the reaction system needs to be kept anhydrous and oxygen-free to ensure the smooth progress of the reaction.
** III. Microbial transformation method **
uses some microorganisms with specific catalytic ability or their enzymes to biotransform the substrate. Screen microbial strains that can catalyze the ethylation of naphthalene compounds and oxidation to quinone, such as certain bacteria or fungi. Naphthalene or its simple derivatives are added to the microbial culture system as substrates, and the microorganisms react with their own enzymes during the growth and metabolism process. This method has the advantages of green environmental protection and mild reaction conditions, but the optimization of microbial culture conditions and the toxic effects of substrates and products on microorganisms need to be further studied and solved in order to achieve large-scale production.
What should be paid attention to when storing and transporting 2,6-difluorobenzyl alcohol?
2% 2C6-diethyl ether acetophenone, when hiding and transportation, be sure to pay attention to all things.
When hiding, choose the first storage place. When looking for a cool, dry and well-ventilated place, avoid direct sunlight. Exposure to sunlight may cause its properties to change, and the heat of sunlight can also promote its chemical changes and damage its quality. In addition, the storage temperature should be controlled in a moderate range. Excessive high temperature can cause its volatilization to accelerate, and even the risk of explosion; too low temperature may cause it to solidify, which is unfavorable for use.
The choice of secondary and container. A closed and material-adapted device must be used to prevent volatilization and leakage. Although glassware is transparent and conducive to observation, it must be prevented from being fragile; metal containers or chemical reactions with them should also be selected with caution. Plastic materials are not suitable if they are not resistant to corrosion.
When shipping, it is essential to load safely. Make sure that it is fixed in the transport equipment without shaking, so as not to damage the container due to bumps and collisions. The transporter should be familiar with its nature and know the emergency measures. If there is a leak, they can quickly take appropriate measures to minimize the harm.
During transportation, avoid passing through densely populated areas to prevent endangering everyone in case of accidents. And the car should be stable, do not brake or turn sharply, and ensure the smooth transportation process.
Also, when handling, handle it with care and do not treat it rudely. Whether it is hidden or transported, it should be clearly marked, indicating what it is, and showing attention, so that contacts can handle it with caution, so as to ensure the safety of 2% 2C6-diethyl ether acetophenone.