Name | 2,4,6 - trifluorobenzyl alcohol |
Chemical Formula | C7H5F3O |
Molar Mass | 162.11 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 175 - 177 °C |
Density | 1.329 g/cm³ |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | 70 °C |
Purity Typical | ≥98% (by GC) |
Vapor Pressure | Low (estimated due to relatively high boiling point) |
Chemical Formula | C7H5F3O |
Molecular Weight | 162.11 |
Appearance | Colorless to light yellow liquid |
Boiling Point | 185 - 187 °C |
Melting Point | N/A |
Density | 1.325 g/cm³ |
Flash Point | 72 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents |
Vapor Pressure | Low |
Refractive Index | 1.451 - 1.453 |
Stability | Stable under normal conditions |
What are the main uses of 2,4,6-trifluorobenzyl alcohol?
2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%84%E9%86%87, that is, 2,4,6-tribromobenzoic acid, its main uses are as follows:
This substance is used in the field of medicine and is often a key intermediate for the synthesis of specific drugs. Because of its unique chemical structure and activity, it can participate in a series of chemical reactions to help build complex drug molecular structures. For example, in the synthesis process of some antibacterial drugs, 2,4,6-tribromobenzoic acid can provide key bromine atoms and carboxyl groups. After specific reaction steps, the final synthesized drug has good antibacterial properties and shows strong inhibition and killing ability against specific bacteria.
In the field of materials science, it can be used as a starting material for the synthesis of functional materials. For example, when reacted with specific organic compounds, polymer materials with special photoelectric properties can be generated. Such polymer materials are widely used in organic Light Emitting Diodes (OLEDs), solar cells and other devices. In OLED manufacturing, the polymer material can be used as a light-emitting layer material, giving the device excellent luminous efficiency and color purity, making the display screen clearer and brighter.
In the field of organic synthetic chemistry, 2,4,6-tribromobenzoic acid acts as an important synthetic building block. With its three bromine atoms and carboxyl group activity, it can combine with different organic reagents through nucleophilic substitution, esterification and other reactions to construct rich and diverse organic compounds. Synthetic chemists often use it to expand the structural complexity of organic molecules, lay the foundation for the development and synthesis of new compounds, and then promote the continuous development of organic synthetic chemistry.
What are the physical properties of 2,4,6-trifluorobenzyl alcohol?
2% 2C4% 2C6-tribromophenol is also an organic compound. Its physical properties are quite characteristic, let me tell them one by one.
Looking at its appearance, at room temperature, 2% 2C4% 2C6-tribromophenol is a white to light yellow crystalline solid with a fine texture. Its smell is unique and has a slightly irritating smell.
As for the melting point, it is between 95 and 96 degrees Celsius. This melting point characteristic makes this substance transform from solid to liquid at the corresponding temperature, which can be used as an important reference in substance identification and related experimental operations.
In terms of solubility, 2% 2C4% 2C6-tribromophenol is insoluble in water, but it can be soluble in organic solvents such as ethanol, ether, and acetone. This difference in solubility is due to the difference between its molecular structure and the intermolecular forces of water and organic solvents. Because its molecular polarity does not match the polarity of water molecules well, it is difficult to dissolve in water; and it is suitable for the intermolecular forces of organic solvents, so it can dissolve. This solubility property plays a key role in many chemical operations such as separation, purification, and organic synthesis.
In addition, 2% 2C4% 2C6-tribromophenol has a higher density than water. When placed in water, it will sink to the bottom of the water. This density characteristic is also an important consideration in the separation process of related mixtures.
In summary, the physical properties of 2% 2C4% 2C6-tribromophenol, such as appearance, odor, melting point, solubility, density, etc., have their own characteristics, which are of great significance in chemical research, industrial production and other fields, and are the basis and key for many chemical operations and reactions.
What are the chemical properties of 2,4,6-trifluorobenzyl alcohol?
2% 2C4% 2C6-tribromophenol is an organic compound. Its chemical properties are particularly interesting and valuable to explore.
In terms of its physical properties, 2% 2C4% 2C6-tribromophenol is often in the form of white to light yellow needle-like crystals, with a specific odor. Its melting point is about 95-96 degrees Celsius, which is critical in many chemical operations and identification. It is slightly soluble in water, but in organic solvents such as ethanol, ether, and chloroform, it exhibits good solubility.
On the benzene ring of 2% 2C4% 2C6-tribromophenol, the electron cloud distribution changes due to the substitution of bromine atoms. Bromine atoms have electron-absorbing effects, resulting in a decrease in the electron cloud density of the benzene ring, so its electrophilic substitution activity is weakened compared with phenol. However, under certain conditions, reactions such as halogenation and nitrification can still occur.
Furthermore, in 2% 2C4% 2C6-tribromophenol, the hydroxyl group (-OH) also has certain activity. It can react with bases to form corresponding salts. This reaction property is often a key step in organic synthesis and chemical analysis.
And because its molecular structure contains bromine atoms, 2% 2C4% 2C6-tribromophenol is also used in the field of flame retardancy. When bromine atoms decompose by heat, they can produce gases such as hydrogen bromide, which can dilute oxygen and inhibit the progress of combustion reactions, showing good flame retardant properties.
In summary, 2% 2C4% 2C6-tribromophenol has a variety of chemical properties due to its unique chemical structure. It plays an indispensable role in many fields such as organic synthesis, analytical chemistry, and material flame retardancy. It is a compound worthy of further study in chemical research and industrial applications.
What are the synthesis methods of 2,4,6-trifluorobenzyl alcohol?
The synthesis method of 2% 2C4% 2C6-tribromobenzoic acid has been known for a long time. There are many methods, and the main ones are listed below.
First, based on benzoic acid, obtained by bromination. Take an appropriate amount of benzoic acid first, place it in a reactor, and add an appropriate amount of solvent, such as dichloromethane, to dissolve the benzoic acid. Add a catalyst, such as iron powder or ferric chloride, to promote the reaction. Then add bromine dropwise. When adding dropwise, the temperature should be controlled to a moderate extent to prevent side reactions from being too high. After the bromine is dropped, continue to stir to make the reaction sufficient. After the reaction is completed, separate and purify it by an appropriate method, and obtain 2% 2C4% 2C6-tribromobenzoic acid. < Br >
Second, toluene is used as the starting material. First, toluene is brominated to obtain bromotoluene. When brominated, various isomers of o, m, and p-bromotoluene can be prepared according to different conditions. Then bromotoluene is oxidized to the corresponding bromobenzoic acid. The oxidation method can use strong oxidants such as potassium permanganate and react under appropriate acid-base conditions. After bromobenzoic acid is obtained, bromination is carried out to control the reaction conditions, so that bromine atoms are mainly replaced in the 2, 4, and 6 positions. Finally, after purification, 2% 2C4% 2C6-tribromobenzoic acid can be obtained.
Third, phenol is used as the starting material. Phenol is first reacted with bromine water. Because the phenolic hydroxyl group is a strong activating group, it is easy to make the neighboring and para-hydrogen on the phenyl ring active, and quickly reacts with bromine water to obtain 2% 2C4% 2C6-tribromophenol. Then tribromophenol is carboxylated, and can be converted into 2% 2C4% 2C6-tribromobenzoic acid by reacting with carbon dioxide under appropriate catalyst and pressure and temperature conditions.
Synthesis methods have their own advantages and disadvantages, and should be carefully selected according to actual needs, such as the availability of raw materials, the level of cost, and the purity of the product.
What are the precautions for storing and transporting 2,4,6-trifluorobenzyl alcohol?
2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%84%E9%86%87, its nature is active, and many matters must be paid attention to when storing and transporting.
First word storage. This substance should be stored in a cool and ventilated warehouse. Because of its volatility, high temperature can easily cause its volatilization to intensify, and even cause safety risks. The temperature of the warehouse should be strictly controlled and should not be too high to prevent its chemical properties from changing. And it needs to be kept away from fire and heat sources. This is the risk of ignition. If it encounters an open flame, it may cause a violent reaction. Furthermore, it should be stored separately from oxidizing agents and acids. Because of its active chemical properties, contact with them or biochemical reactions can lead to danger.
As for transportation, there are also many key points. Before transportation, ensure that the packaging is complete and sealed to prevent leakage. During transportation, the speed of the vehicle should not be too fast, avoid sudden braking, to prevent damage to the packaging. Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment. In the event of an accident, they can be responded to in time. And during transportation, they should not stop in densely populated areas or busy areas to prevent leakage from causing harm to the crowd.
In addition, whether it is storage or transportation, those engaged in related operations should be professionally trained and familiar with its characteristics and emergency treatment methods. Daily inspections should also be strengthened to check the storage environment and transportation equipment to ensure safety. In this way, when storing and transporting 2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%84%E9%86%87, risks can be avoided to the greatest extent and the safety of personnel and the environment can be guaranteed.