Chemical Formula | C13H19FN2O |
Molecular Weight | 238.302 g/mol |
Appearance | Solid (predicted) |
Boiling Point | Predicted: around 391.7°C at 760 mmHg |
Melting Point | No data available |
Density | Predicted: around 1.115 g/cm³ |
Logp | Predicted: around 1.44 |
Water Solubility | Poorly soluble in water (predicted) |
Pka | Predicted: around 9.84 |
Flash Point | Predicted: around 190.7°C |
Chemical Formula | C13H19FN2O |
Molecular Weight | 238.301 g/mol |
Appearance | Solid (likely, based on similar compounds) |
Solubility In Water | Low, due to non - polar fluorobenzyl and piperazine groups |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, dichloromethane |
Logp | Estimated around 2 - 3, indicating moderate lipophilicity |
What are the main uses of 2- [4- (3-fluorobenzyl) piperazin-1-yl] ethanol?
2-%5B4-%283-fluorobenzyl%29piperazin-1-yl%5Dethanol, this is an organic compound. Its main use is more common in the field of medicinal chemistry.
In the process of drug development, such piperazine derivatives containing specific substituents often have unique biological activities. Because the piperazine ring can interact with various receptors or enzymes in organisms, and the fluorine atom substitution on the benzene ring can significantly affect the physicochemical properties, lipid solubility and biological activity of the molecule. This compound may be used as a lead compound, and pharmaceutical researchers can modify and optimize its structure to find new drugs with higher activity, better selectivity and lower toxicity and side effects.
In addition, in the field of organic synthetic chemistry, it can also be a key intermediate. Chemists can build more complex organic molecular structures through various organic reactions, expand the diversity of organic compounds, and lay the foundation for the research and development of new medicines and new materials.
In short, 2-%5B4-%283-fluorobenzyl%29piperazin-1-yl%5Dethanol in pharmaceutical chemistry, drug development and organic synthetic chemistry, both play an important role in promoting the development of related fields, and play a role that cannot be ignored.
What are the physical properties of 2- [4- (3-fluorobenzyl) piperazin-1-yl] ethanol
2-%5B4-%283-fluorobenzyl%29piperazin-1-yl%5Dethanol is an organic compound. Its physical properties are very important, and it is related to the performance of this compound in different scenarios.
Under normal temperature and pressure, it is mostly colorless to light yellow liquid. This color and shape are important for identifying and judging the state of the substance.
The boiling point is also an item that cannot be ignored. At a certain temperature range, the compound will change from liquid to gaseous state. The exact value of this boiling point is affected by factors such as ambient pressure. Generally speaking, at standard atmospheric pressure, the boiling point is [specific value], which helps to understand its volatility and behavior during heating.
In terms of melting point, when the temperature drops to a certain extent, the compound will solidify from liquid to solid, and the temperature of this transition is the melting point. Its melting point also has a specific value, about [specific value], which is of great significance for storage and processing of the substance. If the ambient temperature is lower than the melting point, the substance is in a solid state, which is convenient for storage and transportation; if it is higher than the melting point, it is necessary to pay attention to its liquid properties.
Solubility is also a key physical property. In organic solvents, such as common ethanol and ether, 2-%5B4-%283-fluorobenzyl%29piperazin-1-yl%5Dethanol exhibit good solubility and can be miscible with these organic solvents. However, in water, its solubility is relatively limited. This difference in solubility is a key consideration when separating, purifying and selecting chemical reaction media.
Density is also a property that cannot be ignored. At a specific temperature, its density has a certain value, which is about [specific value] g/cm3. This density data provides an important reference for accurately measuring the volume of the substance to determine the mass, or for separating operations due to density differences in mixtures.
In summary, the physical properties of 2-%5B4-%283-fluorobenzyl%29piperazin-1-yl%5Dethanol, such as morphology, boiling point, melting point, solubility and density, are of great significance in its research, production, storage and application, and provide a basic basis for the planning and control of related operations and reactions.
What is the chemical synthesis method of 2- [4- (3-fluorobenzyl) piperazin-1-yl] ethanol
To prepare 2 - [4 - (3 - fluorobenzyl) piperazine - 1 - yl] ethanol, you can follow the following method. First take 3 - fluorobenzyl chloride and piperazine, make it in an appropriate solvent, such as acetonitrile, add a base, such as potassium carbonate, heat and stir to promote nucleophilic substitution, and get 1 - (3 - fluorobenzyl) piperazine. During this step of reaction, conditions such as temperature control and time are required to ensure that the reaction is sufficient. < Br >
Then take the prepared 1- (3-fluorobenzyl) piperazine, and 2-chloroethanol, add a base, such as triethylamine, with a suitable solvent, such as toluene, and heat reflux. In this process, pay close attention to the reaction process. After the reaction is completed, the product can be purified by common separation methods, such as extraction and column chromatography, to obtain 2- [4- (3-fluorobenzyl) piperazine-1-yl] ethanol.
Each step of the reaction requires fine operation, paying attention to the selection of solvent, the proportion of reactants, and the control of reaction conditions, in order to achieve the expected yield and purity.
What is the price range of 2- [4- (3-fluorobenzyl) piperazin-1-yl] ethanol in the market?
I don't know the price range of "2 - [4 - (3 - fluorobenzyl) piperazin - 1 - yl] ethanol" in the market. This compound is not widely known and commonly used, and its price is affected by many factors.
First, the difficulty of preparation has a great impact. If the preparation requires cumbersome steps, rare raw materials or special conditions, the cost must be high and the price is not cheap. Second, the amount of market demand is related to the price. If the demand is strong and the supply is limited, the price will rise; if the demand is low, the price may be relatively low. Third, purity is also the key. For high purity, the price is much higher than for low purity due to the increased difficulty of preparation.
And this compound is very commercially available, or only needed in specific scientific research, pharmaceutical and other fields. To know its exact price range, consult chemical raw material suppliers, reagent sellers, or explore on relevant professional trading platforms. However, due to the changeable market dynamics, prices often fluctuate, it is difficult to immediately specify its price range.
What are the safety and toxicity of 2- [4- (3-fluorobenzyl) piperazin-1-yl] ethanol
There is now a product called 2 - [4- (3-fluorobenzyl) piperazine-1-yl] ethanol, to know its safety and toxicity. The safety and toxicity of this substance are related to many aspects, and it is difficult to generalize.
First of all, safety is different in different environments and conditions. If properly stored, placed in a cool, dry and ventilated place, away from dangerous substances such as fire sources and oxidants, it may be stable and reduce safety risks. However, if stored improperly, in case of high temperature, humidity, or mixed with incompatible substances, it may cause chemical reactions, causing its properties to change, endangering safety.
As for toxicity, it also needs to be considered more. From an experimental perspective, animal experiments may provide clues. If experimental animals are exposed to toxins orally, percutaneously or by inhalation, and their reactions, such as behavioral changes, abnormal physiological indicators, etc., toxicity can be preliminarily inferred. However, animals and humans have different physiological structures, and the results are for reference only. From the perspective of human contact, if you accidentally touch the skin, or cause irritation, such as redness, swelling, and itching; if you inhale its volatiles, or cause respiratory discomfort, such as cough and asthma. If you eat it by mistake, it may cause damage to the digestive system and nervous system.
However, in order to accurately determine its safety and toxicity, it is necessary to strictly follow professional standards, and after many rigorous experiments and analyses, a reliable conclusion can be obtained. We should not make judgments based solely on common sense or one-sided cognition.