2 3 Difluorobenzylcyanide
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
2,3-Difluorobenzylcyanide
Chemical Formula C8H5F2N
Molar Mass 153.13 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 100 - 102 °C (20 - 22 mmHg)
Melting Point N/A
Density 1.195 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 86 °C
Refractive Index 1.485 - 1.487
Chemical Formula C8H5F2N
Molar Mass 153.13 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 210 - 212 °C
Solubility In Water Insoluble (organic compound, non - polar nature)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether, chloroform
Vapor Pressure Low, typical for a liquid with a relatively high boiling point
FAQ

What are the main uses of 2,3-difluorobenzyl cyanide?

2% 2C3-diethylaminoacetylbenzene, also known as diethylaminoacetylbenzene, is widely used. In the field of medicine, it is an important intermediate in organic synthesis, and the preparation of many drugs is based on it. For example, in the synthesis path of some psychotropic drugs, 2% 2C3-diethylaminoacetylbenzene can be converted into substances with specific pharmacological activities through a series of chemical reactions, which play a key role in alleviating the symptoms of psychiatric diseases.

In the dye industry, it also plays an important role. With its special chemical structure, it can participate in the synthesis of a variety of bright-colored and stable dyes. These dyes are widely used in textile, printing and dyeing industries, giving fabrics rich and colorful colors, and the dyed fabrics have excellent properties in light resistance and washing resistance.

Furthermore, in the research and practice of organic synthetic chemistry, 2% 2C3-diethylaminoacetylbenzene is often used as a starting material or reaction intermediate. Because of the ethylamino and acetylbenzene parts in its structure, it can participate in many organic reactions such as nucleophilic substitution and addition, helping chemists to construct complex and diverse organic molecular structures and promoting the development and innovation of organic synthetic chemistry. In short, 2% 2C3-diethylaminoacetylbenzene plays an indispensable role in the fields of medicine, dyes and organic synthesis.

What are the physical properties of 2,3-difluorobenzyl cyanide?

2% 2C3 -diethylaminoethylbenzene is one of the organic compounds. Its physical properties are as follows:

Looking at its color state, at room temperature, it is mostly a colorless to light yellow transparent liquid, which is quite fluid. Under sunlight, it can be seen that it is clear and shiny.

Smell its smell and emit a special aromatic smell, but this smell is not pleasant and slightly irritating. If people smell it for a long time, or feel uncomfortable, there is a foreign body intrusion between the nose and throat.

In terms of its boiling point, it is about a certain temperature range. When the ambient pressure is standard atmospheric pressure, the boiling point is near a certain value. This value is the key temperature point for the gasification of a substance. At this temperature, the substance gradually changes from liquid to gaseous.

As for the melting point, there is also a specific value. Below this temperature, the substance will change from liquid to solid, and the molecular arrangement will tend to be orderly and tight.

Its density is also an inherent property, and it has a specific ratio compared with water. This density characteristic is very important in many application scenarios, and it is related to the sinking and mixing state of the substance in the medium.

In terms of solubility, in organic solvents, such as ethanol, ether, etc., it shows good solubility and can be miscible with it to form a uniform mixed system. However, in water, the solubility is extremely limited, and the two are mixed, often in a layered state, due to the force between the molecules of the substance and the water molecules.

The physical properties of this substance are of great significance in many fields such as chemical industry and medicine, providing a key basis for its preparation, separation, and application.

What are the chemical properties of 2,3-difluorobenzyl cyanide?

The chemical properties of 2% 2C3 -diethylaminoethylbenzene are particularly important. This compound has the characteristics of an organic compound, in which the ethylamino group is connected to ethylbenzene, resulting in its unique reactivity.

When it comes to physical properties, it is often liquid, has a specific odor, and has a certain volatility. In terms of solubility, it is soluble in common organic solvents, such as ethanol, ether, etc., but it is not well soluble in water. This is because the organic group in the molecular structure dominates and has strong hydrophobicity.

In terms of chemical activity, the nitrogen atom of the ethylamino group has a lone pair of electrons, making it alkaline. It can react with acids to form corresponding salts. For example, in the case of hydrochloric acid, the solitary pair electrons on the nitrogen atom can accept protons and form quaternary ammonium salts.

Furthermore, the benzene ring in the ethylbenzene part is aromatic and can undergo electrophilic substitution reactions. Common reactions such as halogenation reactions, under the action of appropriate catalysts, halogens such as chlorine and bromine can replace hydrogen atoms on the benzene ring. At the same time, the presence of ethylamino groups will affect the electron cloud distribution of the benzene ring, causing the location of the substitution reaction to be selective.

In addition, the carbon-nitrogen and carbon-carbon bonds between ethylamino groups and ethylbenzene on its side chains can also participate in the reaction. Under certain conditions, oxidation, reduction and other reactions can occur, resulting in the derivation of a variety of derivatives, providing important intermediates for the field of organic synthesis.

What is the production method of 2,3-difluorobenzyl cyanide?

The preparation method of 2% 2C3-diethylaminoacetaldehyde is achieved by ancient chemical techniques. The preparation of this aldehyde often follows several ways.

One of them can be obtained by oxidation of the corresponding alcohols. Start with an alcohol and choose a suitable oxidant, such as mild copper oxide or strong oxidizing potassium dichromate. The alcohol is placed in a suitable reaction environment, controlled by temperature, pressure and other conditions, so that the hydroxyl group in the alcohol molecule is oxidized, and then converted into an aldehyde group, and finally 2% 2C3-diethylaminoacetaldehyde is obtained. In this process, the control of temperature is crucial. If the temperature is high, the aldehyde may be further oxidized to carboxylic acid; if the temperature is low, the reaction will be slow and the yield will not be high.

Second, it can also be achieved through the hydrolysis and subsequent oxidation of halogenated hydrocarbons. First, the halogenated hydrocarbons are co-heated with the alkali solution, and the halogenated atoms are replaced by hydroxyl groups to obtain alcohols. Next, the oxidation method, as mentioned above, oxidizes the alcohol to aldehyde. This method requires attention to the selection of halogenated hydrocarbons. Its structure should meet the requirements of the target product, and the concentration of bases and reaction time in the hydrolysis step should be carefully considered to avoid side reactions.

Or it can be prepared by the reduction of carboxylic acid derivatives. If the corresponding esters are used, strong reducing agents such as lithium aluminum hydride are used. Lithium aluminum hydride can reduce the carbonyl group in the ester group to the alcohol hydroxyl group. If the conditions are suitable, the reaction can be further controlled to obtain only the aldehyde group, rather than the complete reduction to the alcohol. In this process, the amount of reducing agent and the choice of reaction medium have a great influence on the reaction process and product purity.

Preparation of 2% 2C3-diethylaminoacetaldehyde requires careful selection of the preparation method according to actual needs, availability of raw materials and equipment conditions, and fine regulation of the reaction elements to obtain satisfactory yield and purity.

What are the precautions for storing and transporting 2,3-difluorobenzyl cyanide?

2% 2C3 -diethylaminoethyl ether is an important organic compound. When storing and transporting, many key precautions must be observed.

First, the storage place should be cool and well ventilated. This substance is volatile when heated. If stored in a high temperature place, it will not only speed up the volatilization rate and cause its loss, but also the volatile gas will accumulate in a limited space. In case of open flame or hot topic, there is a risk of combustion and explosion. Therefore, it needs to be placed in a low temperature environment away from heat sources and fire sources. The optimal temperature should be maintained at 2-8 ° C.

Second, it is necessary to ensure that the storage container is tightly sealed. 2% 2C3 -diethylaminoethyl ether is prone to oxidation reactions in contact with air, which in turn affects its quality. A well-sealed container can effectively isolate air and delay the oxidation process. After taking it, the container should be sealed immediately to prevent outside air from invading.

Third, during transportation, strict shock and anti-collision measures should be taken. Due to its active chemical properties, it may cause chemical reactions or even explosions due to severe vibration or impact. Transportation vehicles need to run smoothly, avoid intense operations such as sudden braking and sharp turns, and should be equipped with corresponding protective equipment and emergency treatment tools.

Fourth, fireworks are strictly prohibited in storage and transportation places. 2% 2C3-diethylaminoethyl ether is a flammable substance. A small open flame or electrostatic spark may cause it to ignite in an instant, causing a disaster. An obvious "no fireworks" sign should be set up in the place, and all behaviors that may generate open flames and static electricity should be strictly prohibited.

Fifth, it needs to be stored and transported separately from oxidants, acids and other substances. 2% 2C3-diethylaminoethyl ether is highly susceptible to chemical reactions in contact with these substances, which may generate harmful substances or cause violent reactions, endangering safety. Therefore, when storing and transporting, it must be strictly separated to avoid mixed transportation.

Only by following the above precautions can we ensure the safety of 2% 2C3-diethylaminoethyl ether during storage and transportation and prevent accidents.