2 3 Difluorobenzyl Bromide
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
2,3-Difluorobenzyl bromide
Chemical Formula C7H5BrF2
Molar Mass 207.015 g/mol
Appearance Colorless to light yellow liquid
Boiling Point ~198 - 200 °C
Density 1.622 g/mL (approximate for liquid)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ether
Vapor Pressure Low at room temperature
Flash Point ~80 °C
Refractive Index n20/D 1.503 (approximate)
Chemical Formula C7H5BrF2
Molar Mass 219.015 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 194 - 196 °C
Density 1.656 g/cm³
Refractive Index 1.502
Flash Point 79.4 °C
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Purity Typically high - purity products around 97%+
Cas Number 175278-74-9
FAQ

What are the chemical properties of 2,3-difluorobenzyl bromide?

2% 2C3 -diethylaminobenzaldehyde is an organic compound with unique physical and chemical properties and wide use in many fields.

Looking at its physical properties, it is mostly light yellow to yellow crystalline powder under normal conditions, with a special odor. The melting point is about 43-44 ° C, and the boiling point is about 282 ° C. It is soluble in organic solvents such as ethanol, ether, and chloroform, and has little solubility in water. This solubility characteristic provides the basis for its application in different solvent systems.

In terms of chemical properties, its aldehyde group is active and can participate in many chemical reactions. It can react with active hydrogen-containing compounds, such as alcohols, to form acetal products. Under basic conditions, aldehyde groups can be oxidized to carboxylic groups to form corresponding benzoic acid derivatives. And the substance has a diethylamino group attached to the benzene ring. This substituent has a donator effect, which increases the electron cloud density of the benzene ring and is more prone to electrophilic substitution reactions, such as halogenation, nitrification, etc. Taking the nitrification reaction as an example, the localization effect of the diethylamino group will cause the nitro group to mainly enter the ortho and para-sites of the benzene ring to generate the corresponding nitro substitution products.

In addition, 2% 2C3-diethylaminobenzaldehyde is often used as an intermediate in the field of organic synthesis, used in the synthesis of a variety of drugs, dyes and other organic compounds. In the field of medicine, some of the compounds it participates in the synthesis In the dye industry, with its reactivity, dye products with specific colors and properties can be synthesized.

What are the main uses of 2,3-difluorobenzyl bromide?

2% 2C3-diethylaminobenzaldehyde is an important raw material for organic synthesis and is widely used in many fields such as medicine, dyes, fragrances, etc.

In the field of medicine, it is often a key intermediate for the synthesis of drugs. For example, in the preparation of some antihistamine drugs, 2% 2C3-diethylaminobenzaldehyde can participate in key reaction steps, and through a series of chemical transformations, the specific structure of the active molecule of the drug is constructed, which helps the drug realize the anti-allergic effect. Due to its structural characteristics, it can react ingeniously with other compounds and precisely introduce the required functional groups, laying the foundation for drug synthesis.

In the dye industry, 2% 2C3-diethylaminobenzaldehyde can be used to synthesize a variety of dyes with bright colors and excellent properties. By reacting with different chemical reagents, dye molecules with specific conjugated structures are generated. Such conjugated structures endow dyes with excellent color characteristics and dyeing fastness, making them suitable for textile, printing and dyeing industries, adding colorful colors to fabrics.

In the field of fragrances, 2% 2C3-diethylaminobenzaldehyde, with its unique chemical structure, can be appropriately modified and reacted to generate fragrance ingredients with special aromas. Such fragrance ingredients can be applied to perfumes, cosmetics and other products to give products a pleasant aroma and enhance the quality and attractiveness of products. < Br >
2% 2C3 -diethylaminobenzaldehyde, as an important organic raw material, plays a pivotal role in the pharmaceutical, dye, fragrance and other industries, and plays an important role in promoting the development of related industries.

What are the synthesis methods of 2,3-difluorobenzyl bromide?

The synthesis method of 2% 2C3-diethylaminobenzaldehyde, although not described in detail in "Tiangong Kaiwu", can now be deduced according to the principles of ancient chemical processes.

Ancient chemical processes rely more on fire and water methods. The fire method is also the method of changing things at high temperature. To make 2% 2C3-diethylaminobenzaldehyde, or you can take benzaldehyde as the base, supplemented by diethylamine, put it in a crucible, and heat it slowly with charcoal fire. During this period, it is necessary to check that the fire is even and not to overheat or overcool. If it overheats, the reactants may decompose; if it is too cold, the reaction will be slow and difficult to advance. At high temperature, the collision between benzaldehyde and diethylamine molecules intensifies, the chemical bond is broken and recombined, or 2% 2C3-diethylaminobenzaldehyde can be obtained.

Water method can also be used as a way. First dissolve benzaldehyde and diethylamine in an alcohol solvent, such as ethanol. Ethanol can be a medium to make the two soluble and evenly dispersed, increasing the chance of contact. Then, drop a little acid catalyst, such as acetic acid. Acid can promote the reaction and reduce the activation energy required for the reaction. Put the mixture in a kettle and heat it in a water bath. The temperature of the water bath is relatively uniform, which can ensure a smooth reaction. As the reaction progresses, the color or taste of the solution changes, which is a sign of the reaction going on.

In addition, it may also be possible to find natural sources. In ancient times, there was a technique of collecting herbs and alchemy, or there were similar structures containing 2% 2C3-diethylaminobenzaldehyde. It can be found in mountains and rivers, and its active ingredients can be extracted by water extraction, alcohol extraction and other methods, and then separated and purified, or pure 2% 2C3-diethylaminobenzaldehyde can be obtained. However, this method requires familiarity with the medicinal properties of plants and trees and the method of extraction, which is not easy.

Although "Tiangong Kaiwu" does not have its details, according to the ancient chemical process wisdom, the synthesis of 2% 2C3-diethylaminobenzaldehyde can be explored by fire, water and natural extraction.

What should be paid attention to when storing and transporting 2,3-difluorobenzyl bromide?

When storing and transporting 2% 2C3-diethylaminobenzene, many key things need to be paid attention to. This substance has a certain chemical activity, and when storing, the first environment should be selected. When placed in a cool and well-ventilated place, it can avoid changes in its chemical properties due to excessive temperature or poor ventilation, and even cause danger. The warehouse should be kept away from fire and heat sources, because the substance may be flammable or react violently after contact with heat or open flame.

Furthermore, the material of the storage container is also critical. It is advisable to use a corrosion-resistant and well-sealed container to prevent it from leaking due to chemical reaction with the container material. If sealed well, it can prevent its volatilization and maintain its chemical stability.

During transportation, it is necessary to strictly follow the regulations for the transportation of hazardous chemicals. Transportation vehicles need to be equipped with corresponding fire protection and emergency treatment equipment to prevent immediate response during transportation. When handling, it should be handled lightly to avoid damage to packaging and containers. And during transportation, it is necessary to control the speed and route of the vehicle, avoid densely populated areas and busy traffic sections, and reduce the risk of accidents.

In short, the storage and transportation of 2% 2C3-diethylaminobenzene should be handled with caution, and all links should be operated in accordance with regulations to ensure the safety of personnel and the environment from pollution.

What are the effects of 2,3-difluorobenzyl bromide on the environment and human body?

2% 2C3-diethylaniline is an organic compound that has many effects on the environment and the human body.

For the environment, if this substance enters the water body, it will cause harm to aquatic organisms. Because of its certain toxicity, it will interfere with the normal physiological functions of aquatic organisms, destroy the balance of aquatic ecosystems, and affect the survival and reproduction of fish and plankton. If released into the soil, it may change the chemical properties of the soil, affect the activity of soil microorganisms, and then have an indirect impact on the growth and development of plants, hinder the absorption of nutrients by plant roots, and reduce plant resistance.

For the human body, 2% 2C3-diethylaniline is irritating. If it is accidentally exposed to the skin, it will cause skin redness, swelling, itching, tingling and other uncomfortable symptoms, and in severe cases, it may even lead to skin allergic reactions. If it evaporates into the air and is inhaled by the human body, it will irritate the respiratory tract, causing symptoms such as cough, asthma, breathing difficulties, and long-term inhalation may also cause damage to lung function. In addition, the substance may also be potentially carcinogenic, and long-term exposure to the environment containing this substance will increase the risk of cancer.

Therefore, in the production, use and treatment of 2% 2C3-diethylaniline, strict protective measures must be taken to reduce its negative impact on the environment and human health.