2 3 6 Trifluorobenzyl Alcohol
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
2,3,6-trifluorobenzyl alcohol
Chemical Formula C7H5F3O
Molar Mass 162.11 g/mol
Appearance Colorless liquid
Boiling Point 170 - 172 °C
Melting Point N/A
Density 1.32 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 69 °C
Vapor Pressure Low vapor pressure
Chemical Formula C7H5F3O
Molar Mass 162.11 g/mol
Appearance Colorless liquid
Boiling Point 184 - 186 °C
Density 1.308 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 75 °C
Refractive Index 1.447
FAQ

What are the main uses of 2,3,6-trifluorobenzyl alcohol?

2%2C3%2C6-%E4%B8%89%E6%B0%9F%E8%8B%84%E9%86%87%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E5%9C%A8%E4%BA%8E%E5%85%B6%E5%90%84%E7%A7%8D%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E4%B8%8E%E7%94%9F%E7%89%A9%E6%80%A7%E8%B4%A8%E5%AF%BC%E8%87%B4%E5%85%B6%E5%9C%A8%E5%88%86%E5%AD%A6%E3%80%81%E5%8C%BB%E8%8D%AF%E3%80%81%E5%86%9C%E4%B8%9A%E7%AD%89%E9%A1%B9%E7%9B%AE%E4%B8%AD%E5%8F%91%E6%8C%81%E7%9B%B8%E5%BD%93%E4%BD%9C%E7%94%A8%E3%80%82

** 1. In the field of analytical chemistry **
It has unique chemical properties and can be used for a variety of analytical tests. If it can have a color reaction with specific reagents, the concentration of certain ions in the solution can be accurately determined by colorimetry. Taking the detection of metal ions as an example, the specific groups in its structure are complexed with metal ions to form complexes with specific colors. Accurate measurement of metal ion content is achieved according to the corresponding relationship between color depth and ion concentration. This method is widely used in water quality monitoring, ore composition analysis, etc., providing an effective way to obtain accurate chemical composition information.

* 2. In the field of medicine **
2%2C3%2C6-%E4%B8%89%E6%B0%9F%E8%8B%84%E9%86%87%E7%9A%84 biological activity should not be underestimated. It has a regulatory effect on the physiological activities of some cells and can be used as a lead compound for drug development. Studies have found that its structure can combine with specific biological targets to affect intracellular signaling pathways, thereby regulating cell growth, differentiation and apoptosis. Some drugs developed based on it have been applied in clinical practice, and have achieved certain curative effects on the treatment of certain diseases such as inflammation and tumors, bringing good news to human health.

** 3. In the field of agriculture **
This substance can be used as a plant growth regulator. Appropriate use can promote plant growth and development, improve crop yield and quality. Its mechanism of action is to regulate the balance of hormones in plants and affect physiological processes such as photosynthesis and respiration of plants. For example, in some fruit and vegetable cultivation, the rational application of preparations containing this ingredient can make the fruits ripen in advance, and the fruits are uniform in size and bright in color, enhance the market competitiveness of agricultural products, and play a positive role in increasing agricultural production and income.

What are the physical properties of 2,3,6-trifluorobenzyl alcohol?

2% 2C3% 2C6-tribromobenzoic acid, this material has the following physical properties:
Its shape is mostly white to light yellow crystalline powder, and the texture is fine. Smell it, and there is little special odor emitted. Its melting point is quite considerable, about 220-225 ° C. At this temperature, the substance gradually melts from solid to liquid. This characteristic makes it have a specific physical state transition temperature node during heating. When used in chemical industry and other fields, this melting point property can help control the reaction conditions.

2% 2C3% 2C6-tribromobenzoic acid has little solubility in water and is extremely difficult to dissolve in water. Due to the weak force between molecular structure and water molecules, it is difficult to form a stable dispersion system. However, in organic solvents, such as common ethanol, ether, etc., it exhibits good solubility and can be miscible with these organic solvents in a certain proportion. This property provides convenience for its use in organic synthesis and related process operations. It can be extracted, separated and reacted with the help of organic solvents.

In addition, the density of this substance is moderate, which is slightly larger than that of water. In practical application and storage, due to density differences, substances with different densities such as water will exhibit layering and other phenomena, which is conducive to the use of density differences for related separation and purification operations, and has important guiding significance for its treatment and application in chemical production and laboratory research. Overall, these physical properties together determine the application and treatment methods of 2% 2C3% 2C6-tribromobenzoic acid in various fields.

What are the chemical properties of 2,3,6-trifluorobenzyl alcohol?

2% 2C3% 2C6-trifluorobenzoic acid has specific chemical properties and is related to many chemical changes. This is a detailed description for you.

This compound is acidic. The carboxyl group (-COOH) exists in its structure, which is the source of acidity. According to the acid-base theory, the carboxyl group can release protons (H 🥰), which are acidic in aqueous solution. When it encounters alkali substances, it can be neutralized with them. For example, when it encounters sodium hydroxide (NaOH), the hydrogen of the carboxyl group combines with hydroxide (OH) to form water, and the rest forms a salt, that is, sodium 2,3,6-trifluorobenzoate. This is the characterization of its acidity and the basis for participating in many organic synthesis reactions. < Br >
Its electrophilic substitution reactivity is unique. The benzene ring is an electron-rich system and is often attacked by electrophilic reagents. However, fluorine atoms (F) are mostly distributed on the benzene ring of 2,3,6-trifluorobenzoic acid. Fluorine atoms have a strong electron-absorbing induction effect (-I), which can reduce the electron cloud density of the benzene ring. In this way, it is more difficult for electrophilic reagents to attack the benzene ring. Compared with ordinary benzoic acid, its electrophilic substitution reactivity is slightly reduced. For example, the common nitration reaction requires more severe reaction conditions and slower reaction rate to nitrate 2,3,6-trifluorobenzoic acid.

Also discusses solubility. Because of its carboxyl group, it has a certain polarity and has a certain solubility in polar solvents such as methanol, ethanol, water, etc. However, the presence of benzene ring and fluorine atoms increases its non-polarity. Fluorine atoms have large electronegativity and strong carbon-fluorine bond polarity, but due to the small radius of fluorine atoms, the intermolecular force has its unique characteristics. Therefore, in non-polar solvents such as benzene and toluene, there is also a certain solubility. This solubility characteristic is crucial for separation, purification and reaction medium selection.

In addition, the stability of 2,3,6-trifluorobenzoic acid is quite high. Fluorine atoms are connected to benzene rings, and the carbon-fluorine bond energy is large, which is not easy to break. This makes the compound less susceptible to structural disintegration due to external factors under normal conditions, and can exist stably in a variety of environments, providing a solid foundation for its application in various chemical processes.

What are the synthesis methods of 2,3,6-trifluorobenzyl alcohol?

There are various ways to synthesize 2% 2C3% 2C6-tribromobenzoic acid.

First, benzoic acid is used as the initial substance and is formed by bromination reaction. In an appropriate reaction vessel, put an appropriate amount of benzoic acid and add an appropriate amount of catalyst, such as iron powder, iron tribromide, etc. Next, bromine is slowly introduced to control the reaction temperature and rate. Because of the benzoic acid on the benzene ring, the carboxyl group is the meta-site group, and the bromine atom will mainly replace it in the meta-site. However, this process requires fine regulation of the reaction conditions. If the temperature is too high or there is too much bromine, it is easy to cause the formation of polybrominates and affect the purity of the product.

Second, it can be started by m-bromotoluene. First, m-bromotoluene is oxidized with an appropriate oxidant, such as potassium permanganate, to convert methyl into carboxyl groups, resulting in 2,3,6-tribromobenzoic acid. The key to this approach lies in the control of the oxidation reaction. The amount of oxidant, reaction temperature and time all have a great impact on the formation of the product. If the oxidation is insufficient, the methyl group is not completely converted; if the oxidation is excessive, it may cause the destruction of the benzene ring.

Third, use phenol as the raw material. First brominate phenol, more bromophenol, and then introduce carboxyl groups through appropriate reactions, such as reacting with carbon dioxide under specific conditions (Kolbe-Schmitt reaction, etc.), and then synthesize the target product. This route step is slightly complicated, but the activity of phenol can be used to selectively realize the steps of bromination and carboxylation. < Br >
Synthesis of 2,3,6-tribromobenzoic acid, each method has its own advantages and disadvantages, and it is necessary to choose the appropriate one according to the actual situation, such as the availability of raw materials, cost, product purity requirements, etc.

What are the precautions for storing and transporting 2,3,6-trifluorobenzyl alcohol?

2% 2C3% 2C6-tribromobenzoic acid, there are many things to pay attention to during storage and transportation.

When storing, the drying environment is the first priority. This substance is prone to change its properties when exposed to moisture, which in turn affects its quality and utility. Therefore, it needs to be placed in a dry place, away from water sources and moisture. And it is appropriate to choose a cool place to avoid high temperature hot topics. Because it is easy to decompose or biochemically react when heated, the original properties are damaged. If the temperature is too high, it may cause structural variation and lose its inherent ability. Furthermore, the storage place should be well ventilated to prevent the accumulation of harmful gases and interact with 2% 2C3% 2C6-tribromobenzoic acid. And must be stored separately, do not mix with other chemicals to prevent mutual reaction and create unpredictable risks.

When transporting, the packaging must be solid and reliable. Appropriate containers are required to ensure that there is no leakage during bumps and vibrations. Packaging materials should be corrosion-resistant to resist the erosion of 2% 2C3% 2C6-tribromobenzoic acid. During transportation, the temperature should be strictly controlled and maintained within a suitable range to avoid sudden temperature changes. The driving should be stable and shock-absorbing to avoid package damage due to excessive shaking. Transport personnel also need to be familiar with its characteristics and emergency measures. In case of leakage, they can quickly and properly dispose of it to avoid major disasters.

In short, when storing and transporting 2% 2C3% 2C6-tribromobenzoic acid, the temperature and humidity of the environment, the ventilation conditions, the stability of the packaging and the professional response of personnel are all key points.