2 3 4 Trifluorobenzyl Bromide
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
2,3,4-trifluorobenzyl bromide
Chemical Formula C7H4BrF3
Molar Mass 225.005 g/mol
Appearance Liquid (usually)
Boiling Point Around 190 - 192 °C
Density ~1.72 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Refractive Index Typically around 1.47 - 1.48
Chemical Formula C7H4BrF3
Molar Mass 225.005 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 180 - 182 °C
Density 1.716 g/cm³
Flash Point 74 °C
Solubility Insoluble in water, soluble in organic solvents like dichloromethane, chloroform
Vapor Pressure Low vapor pressure at room temperature
Refractive Index 1.479 - 1.481
FAQ

What are the physical properties of 2,3,4-trifluorobenzyl bromide?

2% 2C3% 2C4-trihydroxybenzaldehyde is one of the organic compounds. Its physical properties are quite unique.

Looking at its morphology, it is mostly solid at room temperature and pressure, usually white to light yellow crystalline powder, which is easy to store and use. Its odor has a weak aromatic smell, but it is not strong and pungent, and it is relatively mild.

When it comes to solubility, it has a certain solubility in organic solvents, such as ethanol, ether, etc. This property makes it possible to extract, separate and purify it with the help of such organic solvents in chemical experiments and industrial production. The solubility in water is relatively small, because although the molecular structure contains hydroxyl groups, which can form hydrogen bonds with water, the hydrophobicity of the benzene ring is also affected.

Its melting point is within a certain range, and the specific value varies slightly due to factors such as purity, which is roughly at a relatively moderate temperature. The characteristics of the melting point are an important reference for identifying and purifying the substance. The purity of the substance can be judged by accurately measuring the melting point. If the melting point is consistent with the theoretical value and the melting range is narrow, it indicates that the purity is high; conversely, if the melting range is wide, the purity is poor.

The physical properties of 2% 2C3% 2C4-trihydroxybenzaldehyde are of great significance in many fields such as chemical research, drug synthesis, material preparation, etc. Chemists can design suitable synthesis routes and separation methods according to its solubility; drug developers can use its properties to explore its pharmacological activity and medicinal value; material scientists can also use its physical properties to develop new functional materials.

What are the chemical properties of 2,3,4-trifluorobenzyl bromide?

2% 2C3% 2C4 -trihydroxyanisole, that is, methyl gallate, its chemical properties are as follows:

This substance is white to light brown crystalline powder, odorless and slightly bitter in taste. Its melting point is suitable, about 145-149 ° C, and the state of the substance changes at this temperature. It exhibits different solubility in specific solvents, and can be better dissolved in hot water, alcohols, and ethers. This property is related to the hydroxyl and methoxy groups contained in the molecular structure. These polar groups interact with solvent molecules to form and promote the dissolution process.

In terms of chemical activity, due to the presence of multiple hydroxyl groups on the phenyl ring, it has strong reductivity. When encountering an oxidizing agent, the hydroxyl group is easily oxidized and an oxidation reaction occurs. If left in the air for a long time, the color may gradually become darker due to oxidation by oxygen. This property makes it useful as an antioxidant in the fields of food and cosmetics, which can effectively inhibit the deterioration and discoloration caused by oxidation and protect product quality.

At the same time, the hydroxyl group in the molecule can participate in the esterification reaction, and form corresponding esters with acids under the action of catalysts. The presence of methoxy groups affects the distribution of its electron cloud, which has a certain effect on the reaction activity and molecular stability. Under alkaline conditions, it will undergo hydrolysis reaction, and the methoxy group will be separated to form corresponding phenolates and methanol. This reaction may be useful in organic synthesis and analytical chemistry. < Br >
This substance has unique chemical properties and has potential applications in many fields. It plays an important role in chemical reactions and practical applications.

What are the common synthesis methods of 2,3,4-trifluorobenzyl bromide?

The common synthesis method of 2% 2C3% 2C4-tribromobenzyl ether is obtained by taking p-bromotoluene as the starting material and going through several steps.

The first step is the radical substitution reaction between p-bromotoluene and bromine under the action of light or initiator. During this reaction, the hydrogen atom on the methyl group will be gradually replaced by the bromine atom to form benzyl bromide intermediates. This process requires attention to the precise control of the reaction conditions. Factors such as light intensity, temperature and bromine dosage all have a great influence on the selectivity and yield of the reaction products.

In the second step, the generated benzyl bromide intermediate undergoes nucleophilic substitution reaction with phenolic compounds under basic conditions. The presence of alkali can promote the conversion of phenolic hydroxyl groups into phenoxy anions, enhance their nucleophilicity, and thus more easily replace with bromine atoms in benzyl bromide to form ether bonds. At this time, the choice of reaction solvent is also crucial. Commonly used polar aprotic solvents, such as N, N-dimethylformamide (DMF), dimethylsulfoxide (DMSO), etc., help to improve the reaction rate and product yield.

Furthermore, if a specific substitution based on the benzene ring needs to be introduced, it can be achieved through the electrophilic substitution reaction of aromatic hydrocarbons at an appropriate stage. This reaction requires the selection of suitable electrophilic reagents and catalysts according to the structural requirements of the target product, such as the use of Lewis acid catalysts such as iron halide, to achieve the substitution of specific positions on the benzene ring.

In addition, the reaction process needs to be closely monitored during the reaction process. The reaction endpoint can be controlled in a timely manner by means of thin layer chromatography (TLC), gas chromatography (GC) or high performance liquid chromatography (HPLC) to ensure that the reaction proceeds as expected. After the reaction is completed, the product needs to be separated and purified. The commonly used methods include recrystallization and column chromatography to obtain high purity 2% 2C3% 2C4 -tribromobenzyl ether products.

What are the main uses of 2,3,4-trifluorobenzyl bromide?

2% 2C3% 2C4-trihydroxybenzoyl (2,3,4-trihydroxybenzoyl) is commonly found in a variety of natural products, and its main uses are quite extensive.

In the field of medicine, it exhibits significant biological activity. Many studies have shown that compounds containing this group have antioxidant properties, can effectively scavenge free radicals in the body, reduce oxidative stress on cell damage, and then have potential preventive and therapeutic effects on cardiovascular diseases, neurodegenerative diseases, etc. Some natural products or synthetic compounds with this group also exhibit antibacterial and anti-inflammatory activities, can inhibit the growth of a variety of pathogenic bacteria, reduce inflammation, and are of great significance in resisting infectious diseases and inflammation-related diseases.

In the cosmetics industry, its antioxidant properties are also very popular. It can be added to skin care products to help the skin resist free radical attack, delay the aging process of the skin, and keep the skin elastic and shiny. In addition, because of its possible antibacterial properties, it can also maintain the microbial stability of cosmetics and prolong the shelf life of products.

In terms of materials science, 2,3,4-trihydroxybenzoyl groups can be introduced into polymer materials as functional groups. In this way, special properties such as antioxidant and antibacterial properties can be given to materials, broadening the application range of materials in packaging, biomedical materials and other fields. For example, the introduction of this group in food packaging materials can prolong the shelf life of food; in biomedical materials, it helps to prevent the growth of bacteria on the surface of materials and improve the biocompatibility of materials.

In summary, 2,3,4-trihydroxybenzoyl has crucial uses in many fields such as medicine, cosmetics and materials science due to its diverse biological activities and special properties, providing broad space and potential for the development of related fields.

What are the precautions for storing and transporting 2,3,4-trifluorobenzyl bromide?

2% 2C3% 2C4-trihydroxybenzyl ether, both hiding and losing, there are all kinds of things to pay attention to.

When hiding, the first environment. It should be placed in a cool, dry and ventilated place, away from direct sunlight. If it is in a humid place, it is easy to cause deliquescence and deterioration; exposed to the hot sun, it may cause component variation due to light and heat, and damage its quality.

Furthermore, temperature is also the key. It needs to be maintained in a suitable range. Overheating may accelerate the decomposition of this substance, and overcooling may affect its structure, causing its performance to fail.

As for losing, check the packaging carefully first. If the package is damaged, its quality is easily disturbed by external factors, or it may be dangerous due to leakage. And when handling, the action should be slow, and it should not be treated rudely to prevent it from being damaged by earthquakes.

It is also necessary to pay attention to its compatibility with other things. Do not store and transport with mutually exclusive things to prevent chemical reactions, which will cause it to fail in light cases, or cause violent reactions in severe cases, endangering safety. In the choice of transportation means, it should also be in line with its characteristics to ensure stability during transportation.

In short, the storage and transportation of 2% 2C3% 2C4-trihydroxybenzyl ether must be carefully paid attention to the environment, packaging, and compatibility in order to preserve its quality and complete the storage and transportation smoothly.