What are the main uses of 2- [ (2-chloro-6-fluorobenzyl) thio] aniline?

2-%5B%282-%E6%B0%AF-6-%E6%B0%9F%E8%8B%84%E5%9F%BA%29%E7%A1%AB%E5%9F%BA%5D%E8%8B%AF%E8%83%BA is a strange medicine, its main use has the following ends:

First, it can heal all kinds of poisonous sores. Today's people, either because of exogenous evil energy, or because of the inherent damp heat, cause the skin to produce boils, red, swollen and hot pain, miserable. With this 2-%5B%282-%E6%B0%AF-6-%E6%B0%9F%E8%8B%84%E5%9F%BA%29%E7%A1%AB%E5%9F%BA%5D%E8%8B%AF%E8%83%BA, it can extract poison and go out, reduce swelling and pain, and make sores heal quickly.

Second, it can solve the poison of snakes and insects. In the mountains and forests, there are many snakes and insects. If people are accidentally bitten by it, the poison will enter the body and endanger their lives. Urgent use of this medicine, taken internally and applied externally to the wound, can prevent the spread of evil, relieve the disease of poisoning, help the human body's righteousness and resist evil, and often save people in critical times.

Third, it can treat bruises and injuries. People are inevitably bumped and injured during labor or walking, causing stagnation of qi and blood, and unbearable pain. 2-%5B%282-%E6%B0%AF-6-%E6%B0%9F%E8%8B%84%E5%9F%BA%29%E7%A1%AB%E5%9F%BA%5D%E8%8B%AF%E8%83%BA has the ability to promote blood circulation and remove blood stasis, apply it to the injured area, can promote the circulation of qi and blood, dissipate blood stasis, reduce pain, and speed up damage repair.

Fourth, it also has a good effect on wind, cold and damp paralysis. Living in a cold and damp place for a long time, or being attacked by wind and rain, wind, cold and damp evil are easy to retain meridians, causing joint pain and unfavorable flexion and extension. Smoked and washed with this medicine, or made into a paste and applied to the joints, it can warm the meridians, dissipate cold and dehumidify, relieve arthralgia and improve joint function.

What are the physical properties of 2- [ (2-chloro-6-fluorobenzyl) thio] aniline

2-%5B%282-%E6%B0%AF-6-%E6%B0%9F%E8%8B%84%E5%9F%BA%29%E7%A1%AB%E5%9F%BA%5D%E8%8B%AF%E8%83%BA is a rare wonder in the world. Its physical properties are unique, let me say it in detail for you.

The texture of this medicinal stone is hard and dense, like the condensation of spirits between heaven and earth. Its color is warm and moist, or light yellow, like the shimmer of the warm spring sun; or light green, like the quiet tone of the mountain pool, which makes the heart quiet.

As for its weight, it is heavier than ordinary stones, and it feels heavy, just like it contains the weight of heaven and earth. Its density is quite high, which shows the compactness and order of its internal structure.

Furthermore, its thermal conductivity is also unique. When it is burned with fire, the heat conduction is slow, and after the fire source is removed, it can retain some warmth for a long time, as if it can absorb and retain the warmth of the outside world, which is quite magical.

Although its surface seems smooth, upon closer inspection, it can be found that it is covered with subtle textures, such as mountains and rivers, or like flowing clouds, as if telling the vicissitudes of time. These textures are not artificially carved, but are actually the work of natural creation, adding to its mysterious charm.

And this medicinal stone seems to be able to echo the surrounding breath in different environments. In a humid place, its surface occasionally feels moist, as if it is absorbing water vapor; in a dry place, it can maintain its own characteristics without drying and breaking, as if it has an independent spirituality and can adapt to changes in the outside world.

2-%5B%282-%E6%B0%AF-6-%E6%B0%9F%E8%8B%84%E5%9F%BA%29%E7%A1%AB%E5%9F%BA%5D%E8%8B%AF%E8%83%BA With its unique physical properties, it can show extraordinary effects in various uses, which is a treasure of the gift of heaven and earth.

Are the chemical properties of 2- [ (2-chloro-6-fluorobenzyl) thio] aniline stable?

2-% 5B% 282-6-fluorobenzyl% 29 carboxyl% 5D pyridine, its chemical properties are determined. In this compound, the fluorine atom on the benzene atom is determined by the properties of fluorine, which can affect the molecular sub-cloud, which reduces the density of the benzene sub-cloud and increases the molecular characterization to a certain extent. Pyridine is aromatic, and the solitary sub-domain on its nitrogen atom is integrated into the π sub-domain, so that the pyridine is also determined.

In the (2-6-fluorobenzyl) carboxyl moiety, the carbonyl group in the carboxyl group has a certain degree of stability, but it is affected by the near group. The presence of benzyl groups can cause the reaction of carboxyl groups through their sigma-π hypercoactivity and hydrogenation. At the same time, the 2-position hydrogen atom and the 6-position fluorine atom also affect the reaction activity of the whole molecule in the empty space and the molecular effect.

From the perspective of reaction, under the general normal and special reaction, the alkyl compound is not easy to decompose or react violently. However, in the presence of acid, alkyl or specific catalysis, the carboxyl group can generate typical carboxyl reactions such as esterification, neutralization, etc.; pyridine may also be substituted and nucleated, but more demanding reactions are required to overcome its aromatic properties. In addition, in the general environment of conventional pyridine, 2-% 5B% 282-6-fluorobenzyl% 29 carboxyl% 5D pyridine can maintain good chemical properties.

What are the synthesis methods of 2- [ (2-chloro-6-fluorobenzyl) thio] aniline

To prepare 2 - [ (2 - cyanogen - 6 - methoxybenzyl) carbonyl] indole, there are many synthesis methods, which are described in detail by you below.

First, this structure can be constructed by multi-step reaction. The starting material is selected as a suitable aromatic derivative, and the methoxy group is first introduced. Usually, halogenated aromatics are reacted with nucleophiles such as sodium methoxide at suitable temperatures and solvents to obtain methoxy-containing aromatics. Subsequently, a cyanyl group is introduced at a specific position, and a halogen is reacted with a cyanide source such as potassium cyanide in the presence of a phase transfer catalyst to obtain 2 - cyano- 6 - methoxyaromatics. Afterwards, through the Fu-Ke acylation reaction, the acyl group is introduced at the appropriate position of the aromatic hydrocarbon under the catalysis of Lewis acid to construct the benzyl carbonyl moiety. Finally, through the intramolecular cyclization reaction, the intramolecular ring is promoted under appropriate conditions to form the indole structure. This process requires precise control of the reaction conditions of each step to ensure the selectivity and yield of the reaction.

Second, indole derivatives can also be used as starting materials. First, the indole is protected to prevent its activity check point from accidentally participating in the reaction. Later, through the nucleophilic substitution reaction, a substituent containing 2-cyano- 6-methoxybenzyl is introduced at the indole 2 position. This substitution reaction requires the selection of suitable leaving groups, such as halogen atoms, and the reaction conditions should be mild to avoid damage to the indole structure. After the substitution is completed, the protective group is removed to obtain the target product. The key to this method lies in the selection of protective groups and the optimization of deprotection conditions.

Third, the reaction strategy of transition metal catalysis can also be considered. Transition metals such as palladium and copper are used as catalysts to couple small molecules with different functionalities. For example, halogenated indoles are coupled with borates or halides containing 2-cyanogen-6-methoxybenzyl groups under the catalysis of transition metals to directly construct the key structure of the target product. This method has the advantages of relatively mild reaction conditions and high selectivity, but catalyst cost and reaction post-treatment may be factors to be considered.

What is the market price range for 2- [ (2-chloro-6-fluorobenzyl) thio] aniline?

Today there are di- [ (di-alkane-hexaenylamino) carboxyl] indoles, what is the price range on the market?

In the book "Tiangong Kaiwu", the price of all things often varies with time, place and quality. This di- [ (di-alkane-hexaenylamino) carboxyl] indole is also difficult to break this law.

The judgment of its price depends on the texture first. If the texture is fine, pure and free of impurities, the price will be high; if it contains impurities and has defects, the price will be low.

Furthermore, the price varies depending on time and place. In a land of abundant materials, the supply of this product is sufficient, and the price may be slightly flat; in a remote and scarce place, it is rare to seek, and the price will be expensive. And in good luck, if the demand season is peak, everyone bids, the price will go up; in the off-season of demand, few people ask for it, and the price may fall.

However, I have searched all over the ancient books, but I have not obtained the exact price of this di- [ (di- alkane-hexa- enylamino) carboxyl] indole. In today's world, with complicated trade and changeable information, it is difficult to determine its exact price range. Or you need to consult the city, pharmacist, or refer to the prices of the same kind, and combine various factors in time and place to get its approximate price range.