1 5 3 Chloro 2 Fluorobenzyl 2 4 Dimethoxyphenyl Ethanone
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
1-[5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxyphenyl]ethanone
Chemical Formula C18H18ClFO3
Molecular Weight 338.785 g/mol
Physical State Solid (predicted)
Boiling Point 465.3°C at 760 mmHg (predicted)
Density 1.199 g/cm³ (predicted)
Vapor Pressure 4.24E-09 mmHg at 25°C (predicted)
Logp 4.33 (predicted)
Solubility Soluble in organic solvents like dichloromethane, ethyl acetate (predicted)
Flash Point 235.2°C (predicted)
Chemical Formula C18H18ClFO3
Molecular Weight 338.785
FAQ

What is the main use of 1- [5- (3-chloro-2-fluorobenzyl) -2,4-dimethoxyphenyl] ethyl ketone?

1-%5B5-%283-%E6%B0%AF-2-%E6%B0%9F%E8%8B%84%E5%9F%BA%29-2%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E5%9F%BA%5D%E4%B9%99%E9%85%AE%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E5%86%85%E5%AE%B9%E5%8D%8F%E4%B8%8D%E6%96%87%E7%9A%84%E5%86%99%E6%B3%95%E7%9A%84%E9%97%AE%E9%A2%98%E5%8F%AF%E8%83%BD%E6%98%AF%E5%9B%BE%E7%89%A9%E5%90%8D%E7%A7%B0%E4%B8%8E%E5%85%B6%E4%BD%93%E7%94%A8%E7%9A%84%E5%85%B3%E7%B3%BB%E9%97%AE%E9%A2%98%EF%BC%8C%E4%B8%8B%E6%96%B9%E4%BB%A5%E5%8F%A4%E6%96%87%E8%A8%80%E6%96%87%E7%9A%84%E6%A0%BC%E5%BC%8F%E4%B8%BA%E5%88%98%E5%8D%95%E5%85%B3%E4%BA%8E%E6%95%B0%E7%94%A8%E7%9A%84%E5%9B%9E%E7%AD%94%EF%BC%9A

This 1-%5B5-%283-%E6%B0%AF-2-%E6%B0%9F%E8%8B%84%E5%9F%BA%29-2%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E5%9F%BA%5D%E4%B9%99%E9%85%AE%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E5%A6%82%E4%B8%8B%EF%BC%9A

This compound is widely used by healers in the way of pharmacy, or by craftsmen in the way of refining utensils. In the way of medicine, it can be used as an adjuvant to pharmaceuticals and help the development of medicinal power. For example, to treat the disease of wind and cold, it can be used as a guide to make various medicines quickly reach the disease center and drive away cold evils. Its nature is mild, adjustable and the nature of various medicines, in order to prevent severe medicine from injuring.

When craftsmen refine utensils, this 1-%5B5-%283-%E6%B0%AF-2-%E6%B0%9F%E8%8B%84%E5%9F%BA%29-2%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E5%9F%BA%5D%E4%B9%99%E9%85%AE is also wonderful. When casting swords, using an appropriate amount of this agent into the furnace can make the texture of the sword tougher, the edge is sharp and it is not easy to roll the blade. Or in firing ceramics, adding them can improve the color and texture of ceramics, making them more delicate and smooth.

In the art of alchemy, it can be used as a reconciling agent to control the temperature and reaction process of alchemy, so that the quality of alchemy is better and the effect is more significant. In short, this 1-%5B5-%283-%E6%B0%AF-2-%E6%B0%9F%E8%8B%84%E5%9F%BA%29-2%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E5%9F%BA%5D%E4%B9%99%E9%85%AE in many technical fields, because of its unique nature, it has an indispensable function, helping everything go smoothly and achieving remarkable results.

What are the synthesis methods of 1- [5- (3-chloro-2-fluorobenzyl) -2,4-dimethoxyphenyl] ethyl ketone?

To prepare 1 - [5 - (3 - cyanogen - 2 - hydroxyethoxy phenyl) - 2,4 - diethoxy benzyl] acetic acid, there are many synthesis methods, the following are common ones:

The starting material is resorcinol, which is reacted with halogenated acetate in a basic environment to generate the corresponding phenol ester. Subsequently, the phenol ester and halogenated acetonitrile carry out nucleophilic substitution and introduce cyano group. Then it is treated with alkali to realize the inner cyclization of the molecule and construct the key benzofuranone structure. Next, the hydroxyl group at a specific position is modified by reduction, etherification and other steps to introduce ethoxy group. Finally, through hydrolysis and acidification, the ester group is converted into a carboxyl group to obtain the target product.

P-hydroxyacetophenone can also be used as the starting material, first protecting the hydroxyl group, and then reacting with halogenated acetonitrile to introduce a cyano group. Then, through the Fu-gram reaction, the acetyl group is introduced at a specific position in the benzene ring. After that, the ethoxy group is introduced through reduction and etherification, and then deprotected and oxidized, and the final product is obtained.

Or starting from 3-bromo-4-hydroxybenzaldehyde, first react with halogenated acetonitrile, introduce a cyano group, and then protect the aldehyde group with ethylene glycol acetal. After that, the ethoxy group is introduced through nucleophilic substitution, and then deprotected. The aldehyde group is oxidized into a carboxyl group, and the target product can be obtained through a series of reactions.

During synthesis, it is necessary to precisely control the reaction conditions according to the characteristics of each step, such as temperature, pH, reaction time, etc. At the same time, in view of the particularity of cyano and other groups, safety protection is also the key to ensure a smooth and efficient synthesis process.

What are the physicochemical properties of 1- [5- (3-chloro-2-fluorobenzyl) -2,4-dimethoxyphenyl] ethyl ketone

1-% [5- (3-cyano-2-hydroxyethyl) -2,4-diacetylphenyl] acetic acid is an organic compound with multiple physicochemical properties.

It is acidic and can neutralize with bases due to its carboxyl group. For example, it can react with sodium hydroxide to form corresponding carboxylate and water. This property makes it an acidic reagent in some chemical reactions and participates in acid-base neutralization related processes.

The compound contains a variety of functional groups, such as cyano, hydroxy, acetyl and carboxyl groups. Cyanyl groups have high reactivity and can participate in nucleophilic substitution, addition and other reactions, which can be used to introduce new groups and expand molecular structures. Hydroxyl groups can participate in esterification reactions, react with alcohols or anhydrides under appropriate conditions to form ester compounds, which are used in organic synthesis to construct ester bond structures. Acetyl groups give molecules a specific spatial structure and electronic effects, which affect their physical and chemical behavior. In addition to acidity, carboxyl groups can also participate in condensation reactions, form esters with alcohols, or react with amines to form amides.

From the perspective of physical properties, its solubility depends on the molecular structure and functional group characteristics. Generally speaking, the presence of polar functional groups makes them have a certain solubility in polar solvents (such as water and alcohols). Due to the interaction of hydrogen bonds and van der Waals forces between molecules, their melting points and boiling points are affected. When the intermolecular force is strong, the melting point and boiling point are relatively high, which is of great significance for the separation, purification and application of compounds.

1-% [5- (3-cyano-2-hydroxyethyl) -2,4-diacetylphenyl] acetic acid has potential application value in organic synthesis, medicinal chemistry and other fields due to its unique functional groups and physicochemical properties. It can be used as a key intermediate for the synthesis of more complex compounds with specific biological activities or functions.

What is the market price of 1- [5- (3-chloro-2-fluorobenzyl) -2,4-dimethoxyphenyl] ethyl one?

Looking at this question, ask for the market price of 1 - [5 - (3 - cyanogen - 2 - hydroxyethylamino) - 2,4 - diethoxyphenyl] acetamide. However, I have not been involved in chemical business, so it is difficult to determine the price.

The price of the city often changes due to many reasons. First, the price of raw materials fluctuates. If the raw materials for producing this acetamide, such as cyanide, hydroxyethylamine, diethoxybenzene, etc., the price of this acetamide will also be affected by it. Second, the fineness of the craftsmanship. Those who are refined have high yield and quality, and the price is high; on the contrary, the price is low. Third, the supply and demand of the market. Those who ask for it are many, and those who supply it are few, the price will rise; those who ask for it are few, and those who supply it are many, the price will fall. Fourth, brand and goodwill. A well-known brand, trusting to the public, the price may be higher than others.

Although I can't tell its price directly, if you want to know its details, you can visit the city of chemical raw materials and consult all merchants; or check the platform and database of chemical information to obtain the market; you can also ask the experts and experts in the industry for their opinions. Hope you follow this path and get the real price.

What are the relevant safety precautions for 1- [5- (3-chloro-2-fluorobenzyl) -2,4-dimethoxyphenyl] ethyl ketone?

1 - [5- (3-cyanogen-2-chlorobenzyl) - 2,4-diacetylphenoxybenzyl] pentazole alcohol is a chemical substance. There are many safety precautions related to such chemicals, so it needs to be treated with caution.

First, be sure to pay attention to environmental conditions when storing. It should be stored in a cool, dry and well-ventilated place, away from fires and heat sources. Because it has a certain chemical activity, high temperature and humid environment may cause chemical reactions, resulting in deterioration or danger. It needs to be stored separately from oxidants, acids, bases, etc., and must not be mixed to prevent violent reactions.

Second, the operation process should strictly follow the specifications. When using, you need to wear appropriate protective equipment, such as protective glasses, gas masks, acid and alkali-resistant gloves, etc., to avoid direct contact of chemical substances with the skin and eyes, and to prevent inhalation of their dust and vapor. The operation site should be equipped with good ventilation facilities to reduce the concentration of harmful substances in the air. If careless operation causes chemical substances to come into contact with the skin or eyes, you should immediately rinse with a large amount of flowing water and seek medical attention in time.

Third, the transportation link should not be ignored. Before transportation, you need to ensure that the packaging is complete and sealed to prevent leakage. During transportation, you should drive according to the specified route, stay away from densely populated areas, and avoid stopping in residential areas and densely populated areas. In the event of a leak, the surrounding people should be quickly evacuated, and access should be strictly restricted. Emergency responders need to wear protective equipment to deal with