1 4 Fluorobenzyl 1 1 Methylpiperidin 4 Yl 3 4 2 Methylpropoxy Benzyl Urea
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)-3-[4-(2-methylpropoxy)benzyl]urea
Chemical Formula C28H38FN3O3
Molecular Weight 483.62 g/mol
Chemical Name 1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)-3-[4-(2-methylpropoxy)benzyl]urea
FAQ

What are the characteristics of the chemical structure of this product 1- (4-fluorobenzyl) -1- (1-methylpiperidin-4-yl) -3- [4- (2-methylpropoxy) benzyl] urea?

The compound, named 1- (4-hydroxybenzyl) -1- (1-methylpiperidine-4-yl) -3- [4 - (2-methylpropoxy) benzyl] urea, has a unique chemical structure.

Looking at its structure, there are many types of groups connected to each other. First, the presence of the 4-hydroxybenzyl moiety, the presence of the hydroxyl group gives it a certain hydrophilicity, which can participate in the formation of hydrogen bonds, play a key role in intermolecular interactions, or affect its solubility and biological activity. In the structure of 1-methylpiperidine-4-yl, the rigid structure of the piperidine ring constrains the overall conformation of the molecule, and the introduction of methyl groups changes the distribution of its electron cloud, affecting its chemical properties and steric hindrance, or interacting with specific receptors, resulting in specific biological effects.

Furthermore, the presence of 3- [4- (2-methylpropoxy) benzyl] moiety, 2-methylpropoxy-modified benzyl, and long-chain alkoxy groups increases molecular hydrophobicity, or helps it penetrate biological membranes. The conjugated system of benzyl phenyl ring enhances molecular stability, and can produce π-π stacking with other aromatic systems, which is of great significance in molecular recognition and crystal structure formation.

Urea group, as the key to connecting various parts, has unique chemical activity and hydrogen bond donor and receptor capabilities, can form a rich hydrogen bond network, stabilize molecular structure, and is widely used in crystal engineering, drug design and other fields. < Br >
The delicate structure of this compound, the synergistic action of various groups, determines its physical, chemical and biological properties, laying the foundation for its potential applications in medicine, materials and other fields.

What are the main uses of 1- (4-fluorobenzyl) -1- (1-methylpiperidin-4-yl) -3- [4- (2-methylpropoxy) benzyl] urea?

1 - (4-hydroxyethyl) -1 - (1-methyl and other - 4-yl) - 3 - [4 - (2-methylethoxy) ethyl] ether, its main use is as a raw material in the pharmaceutical field. Looking at this structure, it contains a variety of groups, or plays a key role in drug synthesis.

In pharmaceuticals, the characteristics of groups can affect drug activity, solubility and stability. For example, hydroxyethyl is hydrophilic, or increases drug water solubility, which facilitates absorption and transportation. Methyl and other alkyl groups, or change the molecular space conformation, affect binding to targets.

This compound may be an intermediate, chemically modified to obtain a drug with specific pharmacological activity. With its structure, targeted, highly effective and low-toxicity drugs can be designed and synthesized, such as anti-tumor and antiviral drugs.

Furthermore, it may be used to develop drugs for the nervous system and cardiovascular system. Its unique structure may interact with specific receptors and enzymes to regulate physiological processes and achieve therapeutic purposes.

Or it may be used to optimize the performance of existing drugs. By introducing this structure, pharmacokinetic properties can be changed, such as prolonging half-life and reducing toxic and side effects.

In summary, 1 - (4 - hydroxyethyl) - 1 - (1 - methyl and other - 4 - yl) - 3 - [4 - (2 - methethoxy) ethyl] ethers are of great significance in pharmaceuticals and provide a key foundation for innovative drug development.

What are the synthesis methods of 1- (4-fluorobenzyl) -1- (1-methylpiperidin-4-yl) -3- [4- (2-methylpropoxy) benzyl] urea?

To prepare 1- (4-furyl) -1- (1-methylimidazole-4-yl) -3- [4 - (2-methylpropoxy) furanyl] urea, the synthesis method is not detailed in "Tiangong Kaiji", but there are various paths to follow in today's organic synthesis chemistry.

First, it can be started from furan and suitable halogenated hydrocarbons. With furan as the base, the halogenated hydrocarbons first undergo nucleophilic substitution reaction with it, and the required hydrocarbon groups are introduced to obtain derivatives containing furan groups. In this process, suitable bases and solvents need to be selected to promote the smooth reaction. If potassium carbonate is used as a base and acetonitrile is used as a solvent, halogenated hydrocarbons and furans can be bonded under the condition of heating and refluxing.

Second, for the introduction of 1-methylimidazole-4-group. 1-methylimidazole can be synthesized first, and a specific group can be introduced at its 4-position through a multi-step reaction. Usually imidazole is used as a raw material, and 1-methylimidazole is first methylated to obtain 1-methylimidazole, and then the target group is connected at the 4-position by electrophilic substitution or nucleophilic substitution reaction. The reaction conditions need to be precisely controlled, and temperature and the proportion of reactants are all key.

Third, when synthesizing 4- (2-methylpropoxy) furan group, furan phenol can be reacted with 2-methylpropyl halide under alkaline conditions. Sodium hydroxide can be selected for the base, and dimethylformamide can be selected for the solvent. This reaction can introduce 2-methylpropoxy at the 4-position of furan phenol.

Finally, the above intermediates containing different groups are condensed to form the target product 1- (4-furanyl) -1- (1-methylimidazole-4-yl) -3- [4- (2-methylpropoxy) furanyl] urea. In the condensation reaction, a suitable condensation agent, such as carbodiimide, can be used to connect the groups under mild conditions to obtain this urea compound. The whole synthesis process requires fine operations such as reaction conditions and purification of intermediates to obtain products with higher yield and purity.

What are the precautions for using 1- (4-fluorobenzyl) -1- (1-methylpiperidin-4-yl) -3- [4- (2-methylpropoxy) benzyl] urea?

1-%284-%E6%B0%9F%E8%8B%84%E5%9F%BA%29, 1-%281-%E7%94%B2%E5%9F%BA%E5%93%8C%E5%95%B6-4-%E5%9F%BA%29, 3-%5B4-%282-%E7%94%B2%E5%9F%BA%E4%B8%99%E6%B0%A7%E5%9F%BA%29%E8%8B%84%E5%9F%BA%5D%E8%84%B2%E7%94%A8%E4%B9%8B%E9%97%B4, need to pay attention to many matters.

First, these chemical agents have specific chemical activities and reaction characteristics. When using 1-%284-%E6%B0%9F%E8%8B%84%E5%9F%BA%29, it is necessary to carefully observe the reaction with surrounding substances. Because it contains specific functional groups, it is easy to chemically react with some active substances, or cause impure products, or unexpected side reactions, so it is necessary to clarify its chemical properties before use, and the properties of the substances in contact with it to avoid adverse reactions.

Second, 1-%281-%E7%94%B2%E5%9F%BA%E5%93%8C%E5%95%B6-4-%E5%9F%BA%29 cannot be ignored. The groups in its structure exhibit different reactivity under specific conditions. Especially in the presence of catalysts or in specific temperature and pressure environments, or in complex situations such as chain reactions. When using, it is necessary to precisely control the reaction conditions and operate according to the standard process to prevent the reaction from getting out of control and endangering safety.

Third, 3-%5B4-%282-%E7%94%B2%E5%9F%BA%E4%B8%99%E6%B0%A7%E5%9F%BA%29%E8%8B%84%E5%9F%BA%5D%E8%84%B2 is equally critical. Its complex structure determines its changeable reaction. During use, not only its own stability should be considered, but also the order in which it is added with other reagents should be paid attention to. Improper order or excessive local concentration may cause violent reactions. And such substances are mostly sensitive to the environment, and changes in temperature and humidity may affect their performance and reaction results, so the storage and use environment should be strictly controlled.

Furthermore, these substances may be toxic and corrosive to a certain extent. When operating, be sure to take comprehensive protective measures, such as protective clothing, protective gloves and goggles, to avoid contact with skin and eyes. In case of inadvertent contact, it should be dealt with immediately according to the emergency treatment process to ensure personal safety. In short, the use of these substances needs to be rigorous and meticulous, and follow the specifications to ensure the smooth progress of the experiment or production.

What are the market prospects for 1- (4-fluorobenzyl) -1- (1-methylpiperidin-4-yl) -3- [4- (2-methylpropoxy) benzyl] urea?

Today, there are 1- (4-furyl) -1- (1-methylpyridine-4-yl) -3- [4- (2-methylethoxy) furyl] urea, and its market prospects are as follows:


View this 1- (4-furyl) -1- (1-methylpyridine-4-yl) -3- [4- (2-methylethoxy) furyl] urea, which has great potential in the field of medicine. Nowadays, many diseases urgently require more effective treatment methods. This compound may emerge in drug research and development due to its unique molecular structure. The combination of furyl and pyridyl in its structure gives it special chemical activity, or it can precisely act on specific biological targets, paving the way for the creation of new drugs.

In the field of pesticides, this urea compound also has potential. At present, there is a growing demand for high-efficiency, low-toxicity and environmentally friendly pesticides. Due to its structural characteristics or good biological activity, this substance can effectively resist pests and diseases, and compared with traditional pesticides, it has less impact on the environment. It is expected to play a role in the development of green pesticides.

Furthermore, the road of scientific research and exploration is never-ending. The unique structure of this compound will surely inspire scientific researchers to explore more potential properties and uses of it. With the deepening of research, new application fields may be opened up, injecting new vitality into the chemical, materials and other industries.

However, its market prospects are not completely smooth. The road of new drug development is long and difficult, and it needs to be verified by a large number of experiments. From cell experiments, animal experiments, to clinical trials, there are many barriers that need to be dealt with cautiously. In the pesticide market, it is also necessary to face fierce competition. How to stand out and be recognized by farmers also needs careful planning.

In summary, 1- (4-furyl) -1- (1-methylpyridine-4-yl) -3- [4- (2-methylethoxy) furanyl] urea faces challenges, but its potential market opportunities are also considerable. With time, careful research and promotion may be able to shine in related fields.