Chemical Formula | C6H4ClF |
Molecular Weight | 116.546 g/mol |
Appearance | Colorless liquid |
Odor | Aromatic odor |
Boiling Point | 121 - 123 °C |
Melting Point | -45 °C |
Density | 1.22 g/cm³ at 20 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in many organic solvents |
Vapor Pressure | 1.73 kPa at 20 °C |
Flash Point | 28 °C |
Chemical Formula | C6H4ClF |
Molecular Weight | 116.546 g/mol |
Appearance | Colorless liquid |
Odor | Aromatic odor |
Boiling Point | 129 - 131 °C |
Melting Point | -45 °C |
Density | 1.22 g/cm³ at 20 °C |
Solubility In Water | Insoluble |
Vapor Pressure | 1.33 kPa at 29.2 °C |
Flash Point | 32 °C |
Refractive Index | 1.511 (20 °C) |
Chemical Formula | C6H4ClF |
Molar Mass | 116.546 g/mol |
Appearance | Colorless liquid |
Odor | Aromatic odor |
Density | 1.198 g/cm³ (at 20 °C) |
Boiling Point | 131 - 132 °C |
Melting Point | -29 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in many organic solvents |
Vapor Pressure | 1.33 kPa at 28.4 °C |
Flash Point | 32 °C |
What are the main uses of Chlorofluorobenzene?
Halogenated chlorofluorobenzene (Chlorofluorobenzene) is an important class of organic compounds. Its main uses cover a wide range of fields.
In the field of medicinal chemistry, halogenated chlorofluorobenzene is often a key intermediate in the synthesis of drugs. The unique properties of chlorine and fluorine atoms on the coine ring can endow the synthesized drugs with specific activity and pharmacological properties. For example, some drugs containing halogenated chlorofluorobenzene structures have excellent antibacterial and antiviral effects. Due to the electronegativity difference between chlorine and fluorine atoms, it can affect the interaction between drugs and biological targets, enhance the affinity and selectivity of drugs, and thus improve the efficacy of drugs.
In materials science, halogenated chlorofluorobenzene also plays an important role. Can be used to prepare high-performance polymer materials. Polymers polymerized from it often have excellent thermal stability, chemical stability and mechanical properties. These materials can be used in high-end fields such as aerospace, electronics and electrical appliances. For example, parts of aerospace equipment need to withstand extreme environments, and this type of polymer material can meet the demand with its characteristics.
In the field of pesticides, halogenated chlorofluorobenzene is often an important component in the synthesis of high-efficiency pesticides. Its structure can endow pesticides with good biological activity and environmental adaptability. It can accurately act on the physiological targets of pests, effectively kill pests, and has relatively suitable degradation properties in the environment, reducing long-term negative effects on the ecological environment.
In summary, halogenated chlorofluorobenzenes are indispensable in the fields of medicine, materials, pesticides, etc., and have made great contributions to the development of modern chemical industry and related application fields.
What are the physical properties of Chlorofluorobenzene
Halogenated chlorofluorobenzene is a class of organic compounds. Its physical properties are quite specific.
First of all, its phase state, under room temperature and pressure, is mostly liquid, but some are solid due to structural differences. Looking at its color, it is often a colorless or slightly colored liquid, which is transparent and clear.
Again on its odor, halogenated chlorofluorobenzene often has a special smell, or irritation, or fragrance, all of which vary depending on the specific structure.
As for its solubility, the solubility of water is very small, which is due to the large difference between molecular polarity and water molecular polarity. However, in organic solvents such as ethanol, ether, benzene, etc., it exhibits good solubility. Due to the principle of "similar miscibility", the polarity of organic solvents is similar to that of halogenated chlorofluorobenzene.
Its boiling point also follows a regular pattern. Generally speaking, with the increase of halogen atoms and benzene ring substituents in the molecule and the increase of molecular weight, the intermolecular force increases, and the boiling point also increases. The melting point is also affected by the molecular structure. Molecules with good symmetry have regular lattice arrangement and relatively high melting point.
In addition, the density of halogenated chlorofluorobenzene is usually greater than that of water. When placed in water, it often sinks to the bottom of the water. The vapor pressure increases with the increase of temperature, and at a certain temperature, a considerable amount of vapor will escape, which is also related to the volatility of the substance.
What are the chemical properties of Chlorofluorobenzene?
The halogenated chlorofluorobenzene is a class of organic compounds in which chlorine and fluorine atoms replace the hydrogen atoms on the benzene ring. Its chemical properties are unique, and it is co-structured by the structure of the benzene ring and the characteristics of the halogen atom.
The benzene ring has a conjugated system, which is stable and aromatic. The introduction of halogen atoms makes the distribution of the molecular electron cloud easier, and the chemical properties are completely different from those of benzene.
First, the nucleophilic substitution reaction. Halogen atoms have strong electronegativity, causing the electron cloud density of the benzene ring to decrease, especially the ortho and para-position. Therefore, the pro-nuclear reagent can attack the carbon atoms connected to the halogen atoms, and the halogen atoms leave to form new compounds. For example, when halogenated chlorofluorobenzene is treated with < Br >
Second, electrophilic substitution reaction. Although the halogen atom reduces the electron cloud density of the benzene ring, the electrophilic substitution reaction activity is inferior to that of benzene, but because it is an ortho-and para-site group, electrophilic reagents still tend to attack ortho-and para-sites. If mixed with nitric acid and sulfuric acid, nitro groups can be introduced into the benzene ring.
Third, elimination reaction. Under strong alkali and heating conditions, halogenated chlorofluorobenzene can undergo elimination reaction, and the halogen atom is removed from the hydrogen atom on the ortho-site carbon atom to form an unsaturated bond.
Fourth, react with metals. Halogenated chlorofluorobenzene can react with certain metals, such as magnesium, in anhydrous solvents such as ether to form Grignard re This reagent has a wide range of uses and can be used to synthesize complex organic compounds.
In short, the synergy effect of halogenated chlorofluorobenzene ring and halogen atom presents a variety of chemical properties, which is important in the field of organic synthesis and is a key intermediate for the creation of many organic materials, drugs and fine chemicals.
What are the precautions in the production process of Chlorofluorobenzene
The halogenated aromatic hydrocarbon chlorofluorobenzene should be paid attention to during the production process.
Safety is the first priority. Chlorofluorobenzene has certain toxicity and irritation. During operation, workers must wear appropriate protective gear, such as gas masks, gloves, protective clothing, etc., to avoid contact with the skin and respiratory tract. And the production site must be well ventilated to prevent it from accumulating in space and causing the risk of poisoning. And it is flammable. During production, it should be kept away from fire and heat sources, and fire prevention should be strictly prevented. Appropriate fire extinguishers and emergency measures should be provided.
Secondary and environmental protection. Waste generated during production, containing chlorofluorobenzene and related by-products, cannot be disposed of arbitrarily. It needs to be properly handled, in accordance with environmental protection regulations, or recycled and reused, or disposed of harmlessly, so as not to pollute the soil, water and atmosphere, and damage the ecological balance.
In addition, the control of the production process is also crucial. Temperature, pressure, reaction time and other conditions are deeply related to the quality and yield of the product. It is necessary to strictly monitor and adjust various parameters according to precise process regulations to ensure the smooth progress of the reaction and reduce the generation of side reactions, so as to achieve the purpose of optimal production and quality improvement.
The maintenance of equipment should not be ignored. Regular inspection and protection of production equipment to ensure that it is airtight and good, without the risk of leakage. And keep the equipment in a good running state, avoiding production failures or safety hazards caused by equipment.
Training of personnel is also essential. Make sure that workers are well aware of the properties of chlorofluorobenzene, the details of the production process, the importance of safety and environmental protection, and improve their operation skills and emergency response capabilities. In this way, only in the production process of chlorofluorobenzene can we ensure safety, improve efficiency and protect the environment.
What is the impact of Chlorofluorobenzene on the environment?
Fluorochlorobenzene is also a benzene series compound containing fluorine and chlorine. Its impact on the environment cannot be ignored.
Fluorochlorobenzene has certain toxicity. If it escapes in the atmosphere, it may migrate with air flow and disperse in a wide area. Its entry into water bodies may cause water quality to deteriorate, and aquatic organisms bear the brunt. Taking fish as an example, fluorochlorobenzene may affect their respiration, feeding and reproduction, causing population changes. In the soil, it may hinder the absorption of nutrients by plant roots, inhibit crop growth, and reduce crop yield and quality.
Furthermore, fluorochlorobenzene is chemically stable, difficult to degrade naturally, and easy to remain in the environment for a long time, accumulating and exacerbating the harm. It may be enriched through the food chain, and it gradually gathers in higher organisms from lower organisms. Humans are at the top of the food chain and are also threatened. Long-term exposure may damage the human nervous system, immune system, etc., causing diseases.
And the organic waste gas generated by the volatilization of chlorofluorobenzene may participate in photochemical reactions to generate photochemical smog, resulting in a decrease in air quality and endangering human health and ecological balance.
Therefore, chlorofluorobenzene has a far-reaching impact on the environment, which is related to ecological security and human well-being. It should be treated with caution, and its emissions should be strictly controlled to prevent it from polluting the environment.