Chemical Formula | C6H2BrF3 |
Molecular Weight | 225.0 |
Appearance | Liquid |
Color | Colorless to light yellow |
Odor | Characteristic odor |
Density | 1.806 g/mL at 25 °C |
Boiling Point | 140 - 142 °C |
Flash Point | 38 °C |
Solubility | Insoluble in water, soluble in organic solvents |
Chemical Formula | C6H2BrF3 |
Molar Mass | 225.0 |
Appearance | Colorless to light yellow liquid |
Boiling Point | 156 - 158 °C |
Density | 1.754 g/mL at 25 °C |
Solubility In Water | Insoluble |
Flash Point | 51.7 °C |
Refractive Index | 1.474 |
Chemical Formula | C6H2BrF3 |
Molar Mass | 225.0 |
Appearance | Colorless to light yellow liquid |
Boiling Point | 145 - 147 °C |
Density | 1.82 g/cm³ |
Solubility In Water | Insoluble |
Flash Point | 47 °C |
Refractive Index | 1.471 |
What are the main uses of 5-bromo-1,2,3-trifluorobenzene?
5% -1,2,3-Sanjiangxiong, its main use has many aspects.
This is important for its use in the body. Its nature is delicious, and it affects the liver, liver, and pericardium. It has the effect of promoting blood circulation and relieving pain. On the bed, it is often used for blood stasis and pain. Such as chest paralysis and heartache, it can dredge the blood of the heart, make the heart pass, and the pain can be obtained. For rib pain, it can cure the liver, remove blood stasis and relieve pain. It is also often used because it can promote blood circulation and remove blood stasis, relieve pain, and help the blood flow. It can be used in combination with pain, such as cold, cold, cold, blood stasis, etc., to remove evil spirits, clear blood, and stop pain.
In health care, it also has its use. It can be eaten with a small amount in the diet, such as the same hoof, which can not add flavor, and can be used to promote blood circulation, so that the blood can be used to achieve a certain purpose of beauty and body care.
In addition, in some folk methods, 5% -1,2,3-Sanjiangxiong is also used. If it is broken, mixed with wine, and applied externally to the body, it can promote blood circulation and remove blood stasis, relieve pain, and help the recovery of the affected part.
However, it is also necessary to be careful when using it. Because of its power to promote blood circulation, it should be used with caution in pregnancy, so as not to damage the fetus and cause the fetal element to be unstable. And the dosage and usage should be followed, but not used, in order to improve its good effect and avoid adverse reactions.
What are the synthesis methods of 5-bromo-1,2,3-trifluorobenzene?
To prepare 5 -% ether - 1,2,3 - tribromobenzene, the synthesis method is as follows:
First, benzene is used as the starting material, and nitrobenzene is obtained by nitrification. This step requires co-heating of concentrated nitric acid and concentrated sulfuric acid. Benzene and concentrated nitric acid are catalyzed and heated by concentrated sulfuric acid. The hydrogen on the benzene ring is replaced by nitro groups. The reaction formula is: $C_ {6} H_ {6} + HNO_ {3} (concentrated) \ xrightarrow [heating] {concentrated sulfuric acid} C_ {6} H_ {5} NO_ {2} + H_ {2} O $.
Then the nitrobenzene is reduced to aniline. Iron and hydrochloric acid are often used as reducing agents. Under the action of iron and hydrochloric acid, nitrobenzene is converted into amino groups. The reaction formula is: $C_ {6} H_ {5} NO_ {2} + 6 [H]\ xrightarrow {Fe + HCl} C_ {6} H_ {5} NH_ {2} + 2H_ {2} O $. After
aniline is obtained, it is reacted with bromine water. The amino group in aniline is a strong activating group, which greatly increases the density of the electron cloud of the benzene ring, and is easily electrophilic substituted with bromine water. 2,4,6 -tribromoaniline can be directly obtained. The reaction formula is: $C_ {6} H_ {5} NH_ {2} + 3Br_ {2}\ rightarrow C_ {6} H_ {2} Br_ {3} NH_ {2}\ downarrow + 3HBr $. Then 2,4,6-tribromoaniline is diazotized with sodium nitrite and hydrochloric acid at low temperature (about 0 - 5 ℃), and the amino group is converted into diazotic salt. The reaction formula is: $C_ {6} H_ {2} Br_ {3} NH_ {2} + NaNO_ {2} + 2HCl\ xrightarrow {0 - 5 ℃} C_ {6} H_ {2} Br_ {3} N_ {2} Cl + NaCl + 2H_ {2} O $.
Finally, using ethanol or hypophosphoric acid as a reducing agent, the diazo group in the diazonium salt is replaced by hydrogen, and the ethanol is oxidized to acetaldehyde, then 5 -% ether - 1,2,3 - tribromobenzene can be prepared. The reaction formula is: $C_ {6} H_ {2} Br_ {3} N_ {2} Cl + C_ {2} H_ {5} OH\ rightarrow C_ {6} H_ {3} Br_ {3} + N_ {2}\ uparrow + HCl + CH_ {3} CHO $.
This series of reactions, through multi-step conversion, with different reaction characteristics, gradually achieve the synthesis of the target product.
What are the physical properties of 5-bromo-1,2,3-trifluorobenzene?
1,2,3-Tribromobenzene is an organic compound. Its physical properties are quite characteristic.
Looking at its properties, under room temperature, 1,2,3-tribromobenzene is white to light yellow needle-like crystals. This shape is clearly distinguishable and easy to distinguish in daily observation.
When it comes to the melting point, its melting point is about 66-68 ° C. When the temperature rises to this range, the substance will gradually melt from solid to liquid; and its boiling point can reach 281 ° C. In higher temperature environments, 1,2,3-tribromobenzene will be converted from liquid to gaseous. This melting boiling point characteristic is of great significance in chemical production, separation and purification, and is related to the design and operation of the process.
As for solubility, 1,2,3-tribromobenzene is extremely insoluble in water, because water is a polar molecule, while 1,2,3-tribromobenzene has a weaker polarity. According to the principle of "similar miscibility", the two are difficult to dissolve. However, it has good solubility in organic solvents such as ethanol, ether, and benzene, and can be miscible with these organic solvents. This property facilitates its application in organic synthesis and other fields.
Its density is also one of the important physical properties. The density of 1,2,3-tribromobenzene is greater than that of water. When it comes to operations such as liquid-liquid separation, this property can help to effectively distinguish and separate. And this material has a certain smell, although not pungent and unpleasant, it also has its own unique smell, which needs to be paid attention to when operating and using.
In short, the physical properties of 1,2,3-tribromobenzene have important effects in chemical industry, scientific research and many other aspects, providing the necessary basis for its rational application and treatment.
What are the precautions for storing and transporting 5-bromo-1,2,3-trifluorobenzene?
5% -1,2,3-tricarbonate is important for storage and aging.
First, durability is very important. 5% -1,2,3-tricarbonate has a specific flow resistance, low durability, its viscosity increases, its flow resistance increases, and the pumping speed rises, and even blockages the pipeline; high durability, it is easy to cause aging and performance deterioration. Therefore, during storage, it is necessary to control the durability. Generally, it is recommended to keep it several degrees above its durability to maintain good fluidity and avoid durability.
Second, anti-corrosion measures are indispensable. This green content may be partially corrosive and irritating. In operation, people should wear anti-wear clothing, gloves, masks, etc., to prevent skin contact, inhalation, and endanger health. Storage containers and pipelines should also be corrosion-resistant to avoid being corroded and causing green leakage.
Third, fire prevention and explosion-proof cannot be ignored. Green flammable materials are prohibited from burning where they are stored, and fire protection should be improved. In addition, it is necessary to pay attention to communication, avoid sexual accumulation, and reduce explosion.
Fourth, avoid pollution. 5% -1,2,3-3-3-3 green storage, to prevent the mixing of oil, such as soil, moisture, etc. Mixing does not affect the performance of green, and the presence of moisture is more likely to cause explosion and become dangerous. Therefore, the storage container needs to be cleaned and sealed, and the entire process should also be well prevented to prevent external pollution.
What is the market price range for 5-bromo-1,2,3-trifluorobenzene?
5% -1,2,3-Sanjiang Hu's city is large, and it is the same as the city. The city is large, and there are often many reasons, such as the size of the city, the size of supply and demand, the size of the city, and the proximity of the place.
First. If the material is fine, the workmanship is good, and the quality is good, it must be high; on the contrary, if it is flawed, it will be low. It is 5% -1,2,3-Sanjiang Hu, and the quality may be as high as a thousand gold, and the inferior one may be worth a hundred.
Let's talk about the supply and demand again. If the city wants it, and it is scarce, it must be high; if the supply is poor, it will decline. If you use the prosperity of this product, or its quantity, it will be expensive; if you use it normally, the supply and shortage will also be equal.
There is also a shortage of energy in this product. For some kinds of energy, there are many people who use this product, such as energy, a specific period, which needs to be greatly increased, or less; and in the normal season, it needs less, or less.
The proximity of the land is also the shadow of the grid. If you are near the land, it will be saved, or low; if you are in the land, the cost of energy and preservation will increase, and the cost will be higher.
According to the above, 5% - 1,2,3 - Sanjiang Huzhi City, less than 10%, more than 1,000%, so as to determine one of the fixed conditions, according to the above reasons, the degree of transformation. Its range, or from 10 to 1000, is possible, and it is also suitable for each situation.