Name | 4-Fluorobenzene-1,2-dicarboxylic anhydride |
Chemical Formula | C8H3FO3 |
Molar Mass | 166.106 g/mol |
Appearance | Solid |
Melting Point | 144 - 146 °C |
Solubility | Soluble in some organic solvents |
Purity | Varies by supplier |
Cas Number | 1139-80-6 |
Chemical Formula | C8H3FO3 |
Molar Mass | 166.106 g/mol |
Appearance | Solid |
Color | White to off - white |
Melting Point | 127 - 130 °C |
Boiling Point | Decomposes |
Solubility In Water | Reacts with water |
Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane |
Chemical Formula | C8H3FO3 |
Molecular Weight | 166.11 |
Appearance | Solid (Typical) |
Melting Point | 148 - 152 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane |
Stability | Stable under normal conditions, avoid heat, flames and oxidizing agents |
Purity | Typically high purity, e.g., 98%+ |
What are the chemical properties of 4-fluorobenzene-1,2-dimethanhydride?
4-Hydroxyquine-1,2-diacetic anhydride is an organic compound with unique chemical properties. Its appearance is often white to light yellow crystalline powder, which is relatively stable at room temperature. However, under specific conditions, its chemical activity is highlighted.
This compound has the typical properties of acid anhydride, and it is easy to hydrolyze in water to form corresponding carboxylic acids. During hydrolysis, the acid anhydride bond breaks and reacts with water to produce carboxylic groups with higher activity. This hydrolysis property is of great significance in the field of organic synthesis, and is often used as a way to introduce carboxyl groups, laying the foundation for the synthesis of complex organic molecules.
The carbonyl group of 4-hydroxyquine-1,2-diacetic anhydride is electrophilic and easily reacts with nucleophiles. Nucleophiles such as alcohols and amines can attack carbonyl carbon atoms and initiate nucleophilic addition reactions. When reacted with alcohols, ester compounds are formed; when reacted with amines, amide compounds are formed. Such reactions are widely used in the preparation of ester and amide derivatives, which can enrich the structure and variety of organic compounds.
Because its molecules contain hydroxyl groups, 4-hydroxyquine-1,2-diacetic anhydride can participate in esterification, etherification and other reactions. The active hydrogen of the hydroxyl group can be replaced by other groups, thereby modifying the molecule and giving it different physical and chemical properties to meet specific needs. In the field of medicinal chemistry, this property can be used to optimize the molecular structure of drugs and improve their pharmacological activity and pharmacokinetic properties.
The conjugated structure of 4-hydroxyquinone-1,2-diacetic anhydride gives it certain optical properties. It may exhibit absorption or emission phenomena under specific wavelength light irradiation, and may have potential applications in optical materials, fluorescent probes and other fields. By modifying its structure, its optical properties can be adjusted and its application range can be expanded.
What are the main uses of 4-fluorobenzene-1,2-dimethanhydride?
4-Bromonaphthalene-1,2-diformic anhydride has a wide range of main uses.
In the field of medicine, this compound can be called an important synthesis intermediate. Through specific chemical reactions, it can be converted into drug molecules with unique physiological activities. For example, when developing some anti-tumor drugs, 4-bromonaphthalene-1,2-diformic anhydride can be used as a starting material to build the core skeleton of the drug through multi-step reactions, giving the drug precise targets and pharmacological activities, and then providing a strong material basis for conquering tumor diseases.
In the field of materials science, it also plays a key role. It can be used to prepare polymer materials with excellent performance. During the polymerization process, 4-bromonaphthalene-1,2-diformic anhydride is integrated into the polymer chain as a functional monomer, which can significantly improve the thermal stability, mechanical properties and optical properties of the material. For example, the prepared new polymer materials may be applied to high temperature resistant electronic device packaging materials, which ensure the stable operation of electronic devices in high temperature environments with excellent thermal stability; or applied to high transparency and good mechanical strength optical lens materials to meet the growing demand for optical materials.
In organic synthetic chemistry, 4-bromonaphthalene-1,2-diformic anhydride is a very commonly used synthetic building block. Due to the unique reactivity of bromine atoms and acid anhydride groups contained in its molecular structure, it can participate in many types of organic reactions, such as nucleophilic substitution reactions, cyclization reactions, etc. Chemists can skillfully use these reactions to construct complex and diverse organic compounds, injecting a steady stream of vitality into the development of organic synthetic chemistry, and helping to synthesize more novel and potentially valuable organic molecules.
What are the synthesis methods of 4-fluorobenzene-1,2-dimethanhydride?
To prepare 4-hydroxy-1,2-diacetate naphthalene anhydride, there are various methods.
First, naphthalene is used as the starting material, and the acetyl group is introduced through the acylation reaction to obtain 1-acetyl naphthalene. Then under specific conditions, the acetyl group is introduced into the 2-position of the naphthalene ring to obtain 1-acetyl-2-acetate naphthalene. After oxidation, the acetyl group and the acetic acid group are converted into carboxyl groups, and the naphthalene ring is oxidized and closed to generate 4-hydroxy-1,2-diacetate naphthalene anhydride. This process requires precise control of the reaction conditions. The acylation reagents and catalysts used in acylation, the oxidizing agent used in the oxidation step and the reaction temperature, etc., all have a great impact on the yield and purity of the product.
Second, a suitable substituted naphthalene derivative can be selected as the starting material. If the starting material has a suitable substituent at the 1-position and 2-position of the naphthalene ring, the target product is constructed through a series of reactions, such as substitution, oxidation, and loop closure. For example, 1-halo-2-carboxylnaphthalene, first through nucleophilic substitution reaction, the halogen atom is replaced with a suitable group, and after modification, it is oxidized and closed-loop to generate 4-hydroxy-1,2-diacetate naphthalene anhydride. The key to this route lies in the selection of the starting material and the precise implementation of the previous substitution reaction to ensure the smooth progress of the subsequent reaction.
Third, the reaction path catalyzed by transition metals is used. Using naphthalene derivatives containing suitable substituents as raw materials, under the action of transition metal catalysts, the target molecular structure is gradually constructed through the formation of carbon-carbon bonds and carbon-oxygen bonds. This method requires high activity and selectivity of the catalyst, and the reaction conditions need to be finely regulated to achieve efficient synthesis.
All these methods have their own advantages and disadvantages. According to actual needs, factors such as the availability of raw materials, the difficulty of reaction conditions, and cost-effectiveness should be weighed, and the optimal method should be selected to prepare 4-hydroxy-1,2-diacetate naphthalene anhydride.
What are the precautions for 4-fluorobenzene-1,2-dimethanhydride during storage and transportation?
Cadmium 4-hydroxyquine-1,2-diacetate is a chemical substance. During storage and transportation, many matters need to be paid attention to.
When storing, the first environment should be heavy. A dry, cool and well-ventilated place should be selected, away from fire and heat sources. Because it may have certain chemical activity, high temperature and humid environment can easily cause its properties to change and cause quality damage. And it needs to be stored separately from oxidants, acids, bases, etc. These substances may chemically react with cadmium 4-hydroxyquine-1,2-diacetate, causing danger. For example, if it coexists with strong oxidants, or causes violent oxidation reactions, it can cause combustion or even explosion.
Furthermore, storage containers are also critical. Containers with good corrosion resistance and sealing must be used. Corrosion and leakage of the container are caused by 4-hydroxyquine-1,2-cadmium diacetate or reaction with certain materials. Glass or plastic bottles of specific materials should be selected to ensure safe storage.
When transporting, the packaging must be firm. Follow relevant transportation regulations and wrap with packaging materials that meet standards to prevent package damage caused by collision and vibration. Transportation vehicles should also be clean, dry, and free of other chemical residues to avoid pollution.
Transportation personnel also need professional training, familiar with the properties of 4-hydroxyquine-1,2-cadmium diacetate and emergency treatment methods. In case of emergencies such as leaks during transportation, they can be dealt with quickly and correctly. In the event of a leak, first isolate the scene, evacuate the crowd, and then collect and clean it with appropriate methods to prevent the spread of pollution.
What is the market price of 4-fluorobenzene-1,2-dimethanhydride?
4-Hydroxyquinoline-1,2-diacetic anhydride, this product is in the market, its price is not fixed, because it varies depending on quality, supply and demand. However, roughly speaking, its price often falls within a certain range.
The price of chemical materials is mostly affected by various factors. One is the price of raw materials. If the raw material used to generate 4-hydroxyquinoline-1,2-diacetic anhydride, the purchase price of its price rises and falls, the price of the finished product will also fluctuate. If the raw material is rare, the price will rise; on the contrary, if the raw material is filled, the price will flatten.
Second, the simplicity of the process is also related to the price. If the method of preparing this product requires exquisite craftsmanship, harsh conditions, or involves many steps and expensive utensils, the cost will be high and the price will not be cheap.
Third, the supply and demand of the market is the key. If the industry has a strong demand for this product, but the producers are limited and the supply exceeds the demand, the price will rise; if the demand is scarce, the goods are in the market, and the supply exceeds the demand, the price will drop.
According to the current market conditions, the price of 4-hydroxyquinoline-1,2-diacetic anhydride is several hundred yuan per kilogram or spectrum. However, the chemical industry market is constantly changing, and if you want to know the exact price, you should consult the specialized merchants and market brokers to obtain an accurate number.