What are the main uses of 3-fluorobenzenesulfonamide?

3 - The main use of these stones is found in the Book of Heavenly Works. It says: "Where is the best way to make a stone first?" It says: "Those who come out of the cave, and those who come out of the mountain, and those who come out of the mountain. The tip of the side is like a chestnut, and it is broken into pieces and fried. Soak it in licorice water for three days, remove the floating one, take the sinking one, and fry it with the previous method. This is the most refined. There are mountain stones, such as the stone, which are slightly blue and black in color, and fry it with white charcoal, which is also made. There is water, and the stone is black, and there are white stars in it, which are broken into the stone, and are made of a board, and the stone is fixed with mud, and it is calmed with fire. The water flows under the board, and the water rises on the stone, and it is filled with a bag. The essence of its color is like snow, so it is called snowflake. "

From this we can see that the use of glycerite is in the stone. There are many kinds of stones, and the glycerite can be used for the stone and the lifting. The method is to first soak the stone in licorice water for three days, remove the floating one, and take the sinking one. This is a preliminary method. It is fried with white charcoal, and can be extracted from the stone. There is also water, which is broken into the water, used to make a plate, made of mud, and calmed by fire. The water flows down, and the water rises above, so each has its own use.

In addition, according to this method, the color of the essence is like snow, and the color of the snow is like snowflakes. But the glycerite played an important role in the ancient process of smelting, and it cannot be used in the water, and it can also help to produce high-quality products.

What are the physical properties of 3-fluorobenzenesulfonamide?

3-Ganshi is a kind of stone, and its physical nature is very special. As far as the shape is concerned, it is often not very smooth, and its surface is rough or slightly rough, and it has a feeling of thickness. The color is mostly white, light or light color, which seems to be a soft color, like a workmanship, elegant but not lost.

Its surface is brittle, with the hand, it has a slight sense of beauty, and the surface of the stone is not very smooth, but it also has a sense of profit. The Mohs hardness is between 5 and 6, and it is not hard. However, it also has a certain degree of strength. The specific gravity is 4.4 to 4.6, and it is placed in the palm of your hand. It feels heavy, and it can be heavy.

In terms of light, it is glass light or light. Under the reflection of the light, it is slightly flooded, like a star. The light is subtle and low, and the non-dazzling light has an implicit beauty. And it has a certain transparency, or is translucent, so that the light can penetrate, and it outlines the surface of the body, which is mysterious.

Its mouth is mostly poor, like a natural cutting, and the surface is uneven. It has a natural quality, which is natural and deliberately carved. In addition, the material rationality of 3-glycerite, such as shape, color, earth, hardness, specific gravity, light, and even mouth, all exhibit the natural appearance of natural materials, and contain the wonderful meaning of heaven and earth creation.

What are the chemical properties of 3-fluorobenzenesulfonamide?

3 - The sweet stone is a medium-grade material, and its chemical properties are special.

This stone has a sweet, flat, and poisonous taste. From a chemical perspective, its main component contains carbonate (ZnCO), and a small amount of ingredients such as oxidation (MgO), oxidation (Fe 2O O), and oxidation (MnO) are mixed into it.

The nature of carbonic acid is easy to melt in case of acid. In case of acid (HCl), it will react, generating chlorination (ZnCl ²), water (H2O) + carbon dioxide (CO2), and its reverse formula is: ZnCO 🥰 + 2HCl → ZnCl 🥰 + H2O O + CO 🥰 ↑. This property allows glycerite to be used as a raw material in some chemical and chemical processes. The oxidizing properties contained in

have the properties of oxidizing oxides, and can combine with acid phases. In case of sulfuric acid (H2O SO), that is, sulfuric acid (MgSO) water, the reverse formula is: MgO + H2O SO→ MgSO+ H2O O.

And oxidation and oxidation also have their own chemical properties. Oxidation energy can react in high temperatures such as carbon monoxide (CO), which is the basic principle of smelting. Oxidation can be used as oxidation or oxidation in a specific oxidation system.

Glycyrrhizite is often used in dispersal and ointment because of its general chemical properties. It is often used in dispersal and ointment. It has the effect of detoxifying the eyesight and retreating the shade and stopping the damage. Its chemical properties do not determine its chemical effect, and it also lays the foundation for its use in different fields.

What is the synthesis method of 3-fluorobenzenesulfonamide?

3-Bromothiophene formaldehyde is an important intermediate in organic synthesis. There are many synthesis methods. The following are common methods:

###Using 3-bromothiophene as the starting material
1. ** Vilsmeier-Haack reaction **:
- ** Reaction principle **: 3-bromothiophene is co-heated with N, N-dimethylformamide (DMF) and phosphorus oxychloride ($POCl_3 $). $POCl_3 $interacts with DMF to form an active intermediate. This intermediate undergoes electrophilic substitution reaction with 3-bromothiophene and introduces formyl groups at the α-position of the thiophene ring. < Br > - ** Reaction steps **: In the reaction flask, first add an appropriate amount of DMF, under low temperature stirring, slowly add $POCl_3 $dropwise, temperature-controlled reaction for a period of time, to generate Vilsmeier reagent. Subsequently, add 3-bromothiophene, heat up to an appropriate temperature, and react for several hours. After the reaction is completed, the reaction solution is poured into ice water for hydrolysis, neutralized to neutral in alkali, and then extracted with an organic solvent. After washing, drying, distillation, etc., 3-bromothiophene formaldehyde can be obtained. This method is relatively simple to operate, and the raw materials are easily available. However, the reaction conditions need to be carefully controlled, and there are many side reactions.
2. ** Gattermann-Koch reaction **:
- ** Reaction principle **: Using 3-bromothiophene as a substrate, under the catalysis of anhydrous aluminum trichloride ($AlCl_3 $) and cuprous chloride ($CuCl $), it reacts with a mixture of carbon monoxide ($CO $) and hydrogen chloride ($HCl $). $AlCl_3 $forms an active complex with $CO $and $HCl $, which prompts the formylation of 3-bromothiophene. < Br > - ** Reaction steps **: In an autoclave, add 3-bromothiophene, $AlCl_3 $and $CuCl $, pass into a dried mixture of $CO $and $HCl $, and react at a certain temperature and pressure. After the reaction is completed, cool, pour the reaction mixture into dilute acid for hydrolysis, and extract, separate, purify and other steps to obtain the product. This method requires high pressure equipment, which requires strict reaction conditions, but has good selectivity.

###Thiophene rings are gradually constructed from other compounds and bromine and formyl groups are introduced
1. ** Using 1,4-dicarbonyl compounds as starting materials **:
- ** Reaction principle **: React with 1,4-dicarbonyl compounds containing appropriate substituents and vulcanizing reagents (such as Lawesson reagents, etc.) to first construct a thiophene ring. If the reaction system is cleverly designed, bromine and formyl groups can be introduced simultaneously or subsequently. For example, if the substituent on one side of the 1,4-dicarbonyl compound contains a bromine atom, the bromine atom can be retained on the thiophene ring during the construction of the thiophene ring; and formyl groups can be introduced by subsequent Vilsmeier-Haack reactions.
- ** Reaction steps **: Mix 1,4-dicarbonyl compounds with vulcanization reagents in appropriate proportions, heat the reaction in an inert solvent, and generate thiophene derivatives. After that, depending on the specific situation, if formyl groups need to be introduced, the Vilsmeier-Haack reaction method can be used to further react and separate and purify 3-bromothiophene formaldehyde. This route design is more flexible, and the product structure can be modified according to different raw materials and reaction conditions. However, there are many reaction steps, and the overall yield may be affected.

What are the precautions for using 3-fluorobenzenesulfonamide?

3-Use this product to pay attention to a lot of things. It is used for the first serious disease, such as constipation, secrecy, and secrecy. If it is used for secrecy, such as the use of laxative for the general purpose, it will not only be effective, but also cause the condition to worsen. It needs to be done according to the cause of the disease.

It is especially careful to use the right amount. Taking the right amount is easy to cause abdominal problems, which is correct, and the liquid is large. It is weak, the mouth is dry, heavy water is lost, and the solution is lost, which is life-threatening. If it is too large, the ability to attack is low, but the amount is not low, and the stomach is affected.

It is also studied for use. It is advisable to take it on an empty stomach in the lower stage, so that the force can be quickly reduced, and the lower stage can be taken at the lower stage, which is less irritating to the stomach. And it should not be used in the later stage. When used in the later stage, the function of the lower channel will be lost, the ability of spontaneous vermiculence will be weak, and the formation of constipation dependent on the body will be formed.

Special people need to be more careful when using it. Women in pregnancy, pregnancy, and menstruation are prone to blood loss, fetal essence, and excessive bleeding. The elderly, young people, and those who are weak, have weak organs, and it is appropriate to use it to prevent it from being correct.

When used in the later stage, food is also indispensable. It should be light, and avoid spicy, oily, and cold things to prevent them from helping the body and aggravating the stomach. If the food is more spicy, it can be used with the same food, and the stomach is more expensive.