Chemical Formula | C8H6F2O2 |
Molecular Weight | 172.13 |
Appearance | Solid |
Melting Point | 108 - 112 °C |
Boiling Point | 256.9 °C at 760 mmHg |
Density | 1.372 g/cm³ |
Solubility In Water | Slightly soluble |
Pka | 3.96 |
Flash Point | 109.2 °C |
Refractive Index | 1.495 |
Chemical Formula | C8H6F2O2 |
Molecular Weight | 172.13 |
Appearance | Solid |
Color | White to off - white |
Odor | Odorless (usually) |
Melting Point | 92 - 96 °C |
Boiling Point | 274.3 °C at 760 mmHg |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, DMSO |
Pka | 3.76 (approximate value) |
Chemical Formula | C8H6F2O2 |
Molar Mass | 172.13 g/mol |
Appearance | Solid (usually white or off - white powder) |
Melting Point | 88 - 92 °C |
Boiling Point | 265 - 267 °C |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, dichloromethane |
Pka Value | Around 3.8 |
Density | 1.378 g/cm³ |
Flash Point | 114.2 °C |
What are the main uses of 3,5-difluorophenylacetic acid?
3,5-Dihydroxybenzoic acid, also known as gentian acid, has a wide range of main uses.
First, in the field of medicine, it has antibacterial and anti-inflammatory effects. It can be used as a raw material for many antibacterial and anti-inflammatory drugs, and can achieve antibacterial purposes by inhibiting specific physiological processes of bacteria. For example, some external antibacterial ointments can enhance the inhibition of common skin infection bacteria, help wounds avoid bacterial invasion, and promote healing. And studies have shown that it may have potential therapeutic value in some inflammation-related diseases, such as arthritis, which can regulate inflammatory factors in the body and reduce inflammatory reactions.
Second, in the cosmetic industry, due to its antioxidant properties, it can capture free radicals and prevent oxidative damage to skin cells. Added to skin care products, it can delay skin aging, make the skin firmer and smoother, reduce wrinkles and pigmentation. At the same time, its antibacterial properties also help maintain the stability of cosmetic microorganisms and prolong shelf life.
Third, in the chemical field, it is an important organic synthesis intermediate. With this as the starting material, through a series of chemical reactions, a variety of compounds with special properties can be synthesized for the preparation of fine chemicals such as dyes and fragrances. For example, in some new functional dyes, 3,5-dihydroxybenzoic acid participates in the construction of a specific molecular structure during the synthesis process, giving the dye its unique color and stability.
What are the physical properties of 3,5-difluorophenylacetic acid?
3% 2C5-diallyl glutaric acid is a kind of organic compound. Its physical properties have several characteristics.
Looking at its appearance, at room temperature, it is mostly a white crystalline solid. Those with pure quality are white in color and have a certain crystal shape, such as fine particles or regular crystals. The surface is smooth and can be crystal clear under appropriate light.
When it comes to the melting point, it is about a specific temperature range. This temperature characteristic is crucial in the identification and separation and purification of substances. When the melting point is reached, the substance gradually melts from solid to liquid, and the transition temperature is relatively stable. If the measured melting point of an unknown substance is consistent with the melting point of 3% 2C5-diallyl glutaric acid, it can be used as one of the basis for preliminary judgment.
Again, its solubility has a certain solubility in some organic solvents, such as ethanol and acetone. In ethanol, under moderate stirring, it can gradually dissolve to form a homogeneous solution. Due to the interaction between the molecules of the substance and the ethanol molecules, the solute is dispersed in the solvent. However, in water, the solubility is poor, because the proportion of hydrophilic groups in the molecular structure is limited, and it is difficult to fully combine with water molecules to form a stable dispersion system.
In addition, the density of the substance is also one of its physical properties. Its density is relatively stable, and under specific conditions, it can provide data support for substance identification and related chemical process design. If in a mixed system, it can be separated according to the density difference. And its volatility is weak, and it is difficult to volatilize into the air at room temperature and pressure. This characteristic makes it relatively stable during storage and use, and it is not easy to lose due to volatilization or cause safety problems.
Is the chemical properties of 3,5-difluorophenylacetic acid stable?
3% 2C5 -divinylbenzoic acid, its chemical properties are still stable in common sense.
In this compound, the styrene ring is a stable structure with aromatic properties, giving it a certain chemical stability. Although the groups of divinyl and benzoic acid each have their own activities, after the combination of the two, under generally mild conditions, it is not easy to spontaneously produce violent chemical reactions.
Although vinyl is unsaturated, in the usual environment, if there are no specific initiation conditions, such as light, catalyst, high temperature, etc., its double bonds are not easy to open on their own and undergo reactions such as addition or polymerization. The acidity of the benzoic acid moiety and carboxyl group can remain relatively stable in general organic systems without encountering specific bases or nucleophiles.
However, when the environment changes, its stability will be affected. In case of strong oxidizing agents, the vinyl group may be oxidized, and the carboxyl group may be further oxidized. If there are suitable catalysts and reaction conditions, the vinyl group may polymerize to form a polymer. Or in the environment of strong acids and bases, its structure may also change.
In summary, 3% 2C5-divinylbenzoic acid is chemically stable under common mild conditions, but its structure and properties may change significantly under special reaction conditions or special chemical environments.
What are the synthesis methods of 3,5-difluorophenylacetic acid?
The synthesis methods of 3,5-diallyl salicylic acid are various and exquisite.
One is based on salicylic acid, so that it can react with allyl halide in an alkaline environment and with the help of a phase transfer catalyst. For bases, sodium hydroxide, potassium carbonate and the like can be selected; phase transfer catalysts, tetrabutylammonium bromide, etc. can be used. In this process, the phenolic hydroxyl group of salicylic acid launches a nucleophilic attack on the halogen atom of allyl halide, and the halogen atom leaves, and then becomes the precursor of 3,5-diallyl salicylic acid. After purification and refining, the pure product can be obtained. The reaction conditions are mild and the operation is not complicated. However, the activity of allyl halide is quite high, and there may be side reactions during the reaction, resulting in damage to the purity of the product.
The second is to use o-hydroxybenzoic acid as the starting material, first by esterification to form an ester, and then by allylation to introduce an allyl group. During esterification, concentrated sulfuric acid and the like are often used as catalysts to form esters with alcohols. Allylation requires specific metal catalysts, such as palladium catalysts. The advantage of this path is that the reaction can be regulated step by step, and the structure of the product can be controlled more precisely. However, the price of metal catalysts is high, and the number of reaction steps increases, and the cost also increases.
Third, the Diels-Alder reaction can be used to construct carbon-carbon bonds. The material with conjugated diene structure and the dienophilic body are used as raw materials. The two are cycloadded to obtain a specific intermediate, and then converted and modified by functional groups to form 3,5-diallyl salicylic acid. This reaction has the characteristics of good atomic economy and good stereoselectivity, but the selection of raw materials and reaction conditions are demanding, and the requirements for reaction equipment and operation skills are very high.
All synthesis methods have their own advantages and disadvantages. In practical application, the optimal method needs to be weighed according to the availability of raw materials, cost considerations, product purity and yield requirements.
What is the price range of 3,5-difluorophenylacetic acid in the market?
In today's world, business conditions are ever-changing, and the value of goods in the market often varies from time to time and place. 3,5-diallyl salicylic acid, its inter-market value is also difficult to determine.
Covers the level of its price, related to various reasons. The first is the trend of supply and demand. If there are many people in the market who want it, and there are few people who supply it, the price will be high; on the contrary, if the supply exceeds the demand, the price will drop. The second is the manufacturing cost. The price of raw materials, the amount of labor costs, and the wear and tear of equipment are all involved in the cost. If the cost is high, the price will also be high. Furthermore, the regulations of government orders, changes in luck, and competition in the same industry can all make the price fluctuate. < Br >
Although it is difficult to determine the geometry of its price, according to past examples and market conditions, its price fluctuates within a certain range. Or due to differences in quality and origin, the price varies. Roughly speaking, those with high quality are expensive; while those with ordinary quality are slightly inferior.
Also, in different places, the price varies due to differences in taxes and freight. Prosperous cities, with convenient transportation and abundant supply of goods, the price may be relatively flat; remote places, with difficult transshipment, the price may be slightly higher.
Market conditions are changing rapidly. If you want to know the exact value of 3,5-diallyl salicylic acid, you must carefully observe the current market conditions, visit merchants, and consult experts to obtain a more accurate number.