Chemical Formula | C15H8F4O |
Molecular Weight | 282.22 |
Chemical Formula | C15H8F4O |
Molecular Weight | 282.216 |
Chemical Formula | C15H8F4O |
Molecular Weight | 282.216 g/mol |
Solubility In Water | Expected to be low due to non - polar nature of the aromatic rings and fluorine substitution |
Solubility In Organic Solvents | Likely soluble in common organic solvents like toluene, dichloromethane due to its non - polar structure |
Vapor Pressure | Low, considering its relatively large molecular size and likely low volatility |
Stability | Should be relatively stable under normal conditions, but may react under strong acidic, basic or oxidizing conditions |
What is the main use of 3- [ (4-vinylphenyl) methoxy] -1,2,4,5-tetrafluorobenzene
3 - [ (4 -ethylphenyl) methoxy] -1,2,4,5 -tetrafluorobenzene, this compound has important uses in many fields.
In the field of materials science, it can be used as a key monomer for the preparation of high-performance fluoropolymers. Because its molecular structure contains both fluorine atoms and specific benzene rings and substituents, it can endow polymers with excellent properties. The introduction of fluorine atoms can enhance the chemical corrosion resistance of polymers, so that polymers can still maintain stable performance in harsh chemical environments such as strong acids and strong bases, and are not easy to be corroded. At the same time, it can also improve the weather resistance of polymers, so that they can be exposed to the natural environment for a long time, resist the erosion of ultraviolet rays, oxygen and other factors, and delay the aging process. The benzene ring structure helps to improve the mechanical properties of polymers, such as strength and hardness, making it have application potential in engineering materials.
In the field of medicinal chemistry, it can act as an intermediate for the synthesis of drug molecules with specific biological activities. The unique structure of this compound can interact with specific targets in organisms, and through rational drug design and subsequent chemical modification, it is expected to develop drugs with novel mechanisms of action. For example, using its binding properties with certain proteins or enzymes to develop innovative drugs for the treatment of specific diseases provides new opportunities for the development of the field of medicine.
In the field of electronic chemicals, it can be applied to the manufacture of high-performance electronic materials. For example, as an important part of the liquid crystal material, it can optimize the arrangement and performance of liquid crystal molecules, so that the liquid crystal display has higher resolution, faster response speed and wider viewing angle, thereby improving the display quality of electronic products and user experience.
What are the physical properties of 3- [ (4-vinylphenyl) methoxy] -1,2,4,5-tetrafluorobenzene
3 - [ (4 -ethylphenyl) methoxy] - 1,2,4,5 -tetrafluorobenzene is an organic compound. Its physical properties are as follows:
This compound is mostly solid at room temperature. Due to the intermolecular forces and arrangements, the molecules are tightly aggregated, resulting in a solid state.
The melting point is in a specific temperature range, and the specific value depends on its purity and the accuracy of the molecular structure. In the field of organic synthesis and materials science, the melting point is a key characteristic, which can help to judge its purity and stability.
The boiling point also has a corresponding range. The boiling point is related to the strength of the intermolecular forces. By heating, the molecules obtain enough energy to overcome the attractive forces between molecules, and then transform into a gaseous state. In terms of solubility,
shows a certain solubility in organic solvents such as dichloromethane and chloroform, which is attributed to the principle of "similar miscibility", that is, the polarity of the compound molecule and the organic solvent molecule is similar, and the force between each other promotes the dissolution process; while in water, the solubility is poor, because the non-polar characteristics of the molecular structure and the polarity of water are quite different, and the interaction between the two is weak.
Density is also a specific value. As a material characteristic, density depends on the close arrangement of molecular mass and molecules, which is of great significance to its behavior and application in different media.
Appearance is often white or off-white solid, and the color and morphology reflect the absorption and scattering characteristics of the molecular structure. In practical applications, the appearance characteristics are helpful for preliminary identification and quality control.
What are the chemical properties of 3- [ (4-vinylphenyl) methoxy] -1,2,4,5-tetrafluorobenzene
3 - [ (4 -ethylphenyl) methoxy] - 1,2,4,5 -tetrafluorobenzene The properties of this compound are as follows:
This compound contains fluorine atoms, which have certain unique properties. Fluorine atoms are highly electronegative, which will have a significant impact on the electron cloud distribution of molecules. From a physical point of view, due to the introduction of fluorine atoms, the intermolecular force changes, causing its melting boiling point to be different from that of similar benzene-based compounds without fluorine. Generally speaking, fluorine-containing compounds have relatively high stability and can resist chemical reactions such as oxidation and hydrolysis to a certain extent.
From the perspective of chemical activity, the substituents on the benzene ring will affect the electron cloud density of the benzene ring, which in turn affects the electrophilic substitution reaction activity. (4-ethylphenyl) methoxy group, as a larger substituent, will produce a steric hindrance effect on the reaction check point on the benzene ring. At the same time, methoxy group is the power supply subgroup, which will increase the electron cloud density of the benzene ring ortho-para, which is conducive to the attack of the electrophilic reagents on the ortho-para; while fluorine atoms have a certain conjugation effect, which also affects the electron cloud distribution of the benzene ring to a certain extent, making the electrophilic substitution reaction activity change compared with the simple benzene ring. In addition, the carbon-fluorine bond energy in this compound is high, and it is relatively difficult to break in some chemical reactions, thus endowing the compound with chemical stability under specific conditions.
In summary, 3- [ (4-ethylphenyl) methoxy] -1,2,4,5-tetrafluorobenzene has special physical and chemical properties due to its unique molecular structure, which may show specific application value in organic synthesis, materials science and other fields.
What are the synthesis methods of 3- [ (4-vinylphenyl) methoxy] -1,2,4,5-tetrafluorobenzene
To prepare 3- [ (4-ethylbenzyl) methoxy] -1,2,4,5-tetrafluorobenzene, there are many synthesis methods, which are described in detail below.
First, it can be started from 4-ethylbenzyl alcohol. First, it reacts with halomethane in the presence of a base to obtain (4-ethylbenzyl) methyl ether. Then, under the action of suitable fluorinating reagents such as hydrogen fluoride pyridine complexes, the benzene ring is fluorinated, and the target product can be obtained through a multi-step reaction. In this process, the choice of halomethane, the type and dosage of base all have a great influence on the reaction. If halogenated methane is selected from iodomethane, its activity is higher and the reaction rate is faster; alkali is selected from potassium carbonate, which is mild and conducive to the reaction.
Second, 4-ethylbenzaldehyde is used as the starting material. First, 4-ethylbenzyl alcohol is obtained by reduction reaction, and then (4-ethylbenzyl) methyl ether is prepared according to the above steps, and then fluorinated. The reduction reaction can choose reducing agents such as sodium borohydride, which have mild reduction performance and high selectivity for aldehyde groups, which can effectively avoid other groups from being affected.
Third, start with 4-ethylbromobenzene. First react with metal magnesium to make Grignard reagent, then react with formaldehyde to obtain 4-ethylbenzyl alcohol, and the subsequent steps are the same as before. When preparing Grignard reagent, the reaction conditions need to be strictly controlled, and an anhydrous and anaerobic environment is indispensable, otherwise Grignard reagent is easy to decompose and affect the subsequent reaction.
Fourth, use p-ethylphenol as raw material. First react with halomethane to protect phenolic hydroxyl to obtain 4-ethylanisole, then introduce benzyl, and finally fluoride. The optimization of the reaction conditions at each step of this route is critical. For example, when introducing benzyl, the choice of reaction solvent and catalyst will affect the reaction yield and selectivity.
The above methods have advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider factors such as raw material availability, cost, and difficulty of reaction conditions, and choose the optimal path to efficiently prepare 3- [ (4-ethylbenzyl) methoxy] -1,2,4,5-tetrafluorobenzene.
What is the price range of 3- [ (4-vinylphenyl) methoxy] -1,2,4,5-tetrafluorobenzene in the market?
Wen Jun's inquiry is about the price range of 3- [ (4-ethylphenyl) methoxy] -1,2,4,5-tetrafluorobenzene in the market. However, the prices of shops often change due to various reasons, such as differences in season, supply and demand conditions, differences in origin, differences in quality, and different prices in different markets.
If you want to know the exact price of this 3- [ (4-ethylphenyl) methoxy] -1,2,4,5-tetrafluorobenzene, or when you go to a chemical trading office, consult all kinds of merchants; or you can ask the online trading platform to see the approximate price; or consult the brokers and experts of chemical materials, who have been involved in this for a long time, or can say it roughly.
However, under normal circumstances, in the market of chemical raw materials, the price may be between a few yuan and tens of yuan per gram. If the dosage is quite large, conduct a large transaction, and negotiate with the supplier, you may be able to get a suitable price. However, this is only the number of ideas, not the exact price, and the actual price is still subject to the market search.