Chemical Formula | C6H3Cl2F |
Molar Mass | 166.99 g/mol |
Appearance | Colorless to pale yellow liquid |
Boiling Point | 176 - 178 °C |
Melting Point | -12 °C |
Density | 1.417 g/cm³ |
Solubility In Water | Insoluble |
Vapor Pressure | 1.33 hPa (25 °C) |
Flash Point | 66 °C |
Refractive Index | 1.515 |
Chemical Formula | C6H3Cl2F |
Molar Mass | 165.00 g/mol |
Appearance | Colorless to pale yellow liquid |
Boiling Point | 172 - 174 °C |
Melting Point | -25 °C |
Density | 1.45 g/cm³ |
Solubility In Water | Insoluble |
Vapor Pressure | 1.33 hPa (39.5 °C) |
Flash Point | 64 °C |
Refractive Index | 1.523 - 1.525 |
Chemical Formula | C6H3Cl2F |
Molar Mass | 165.00 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 175 - 177 °C |
Melting Point | -21 °C |
Density | 1.389 g/cm³ at 20 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | 60 °C |
Refractive Index | 1.5050 - 1.5070 |
What are the main uses of 2,5-dichlorofluorobenzene?
2% 2C5-dihydrofuran, although this substance is not detailed in Tiangong Kaiji, it is widely used in the field of chemistry today.
Its primary use is as a key intermediate in organic synthesis. In the fine chemical industry, the synthesis of many high-value-added compounds relies on 2% 2C5-dihydrofuran as the starting material. For example, some drug molecules with special structures are synthesized, and their unique five-membered ring structure can provide a basis for the construction of drug active sites. Taking the synthesis of a new type of anti-infective drug as an example, 2% 2C5-dihydrofuran is introduced into a specific functional group through several steps to eventually become a drug with high antibacterial activity.
Furthermore, it has also made its mark in the field of materials science. It can be used to prepare polymer materials with special properties. Because it contains unsaturated bonds, it can participate in polymerization reactions and endow polymers with unique physical and chemical properties. For example, polymer materials with excellent optical properties are prepared, which are used in optical lenses, optical fibers and other fields to improve the light transmission and stability of materials.
And 2% 2C5-dihydrofuran is also useful in the fragrance industry. After appropriate modification and transformation, fragrance components with unique aroma can be prepared. Due to the particularity of its structure, it can bring fresh and unique flavor to fragrances, enrich the flavor level of fragrances, and is widely used in the preparation of perfumes, food flavors and other products.
What are the physical properties of 2,5-dichlorofluorobenzene?
2% 2C5-difluorotoluene is an organic compound with unique physical properties, detailed as follows:
1. ** Physical state and color **: Under normal temperature and pressure, 2% 2C5-difluorotoluene is often colorless and transparent liquid, and its pure and impurity-free color state is convenient for observation and operation in many application scenarios.
2. ** Odor **: This substance emits a special aromatic odor, which is related to the structure of aromatic compounds, but different individuals may perceive it differently.
3. ** Boiling point and melting point **: The boiling point is about 157-158 ° C, and the melting point is about -37 ° C. Such a boiling point makes it easy to vaporize under appropriate heating conditions. Distillation and other means can be implemented according to this characteristic in chemical operations such as separation and purification; while the melting point indicates that it is stable as a liquid at room temperature, and it may solidify in low temperature environments.
4. ** Density **: The density is about 1.11g/cm ³, which is slightly heavier than water. This density characteristic is crucial in the process of mixing or separating liquids. Stratified separation from other liquids such as water can be achieved according to density differences.
5. ** Solubility **: 2% 2C5 - Difluorotoluene is insoluble in water, but easily soluble in most organic solvents, such as ethanol, ether, acetone, etc. This solubility is due to the hydrophobicity of its molecular structure, which makes it an excellent solvent in the field of organic synthesis, assisting the dissolution of the reactants and promoting the smooth progress of the reaction.
6. ** Volatility **: 2% 2C5-difluorotoluene is volatile to a certain extent, and will gradually change from liquid to gaseous and diffuse into the air when in an open environment or when the temperature rises. When using, pay attention to this characteristic, operate in a well-ventilated place, and take proper protective measures to prevent the inhalation of excessive volatile gases.
Is the chemical properties of 2,5-dichlorofluorobenzene stable?
The chemical properties of 2% 2C5-difluoroethylbenzene are quite stable. Among this substance, fluorine atoms have unique characteristics. Fluorine is an element with strong electronegativity, and its bond energy with carbon atoms is quite high. Between the molecular structures of 2% 2C5-difluoroethylbenzene, the carbon-fluorine bond is abnormally strong, and it takes a lot of energy to break it.
Furthermore, the basic structure of ethylbenzene gives it a certain chemical inertness. The benzene ring has a stable structure with a conjugated large π bond, which is not easily disturbed by ordinary chemical reagents. Although the substitution of difluorine atoms has an impact on the distribution of its electron cloud, it does not break its fundamental stability.
Under normal chemical reaction conditions, 2% 2C5-difluoroethylbenzene is difficult to react rapidly and violently with common acids and bases, oxidizing agents, reducing agents, etc. In case of common external stimuli such as heating and light, its chemical structure can be maintained relatively stable without special catalysts or reaction conditions.
However, it is not possible that it will never react. In a specific high temperature, high pressure environment, or in the presence of a strong catalyst, its carbon-fluorine bond may also be activated, which may lead to the occurrence of chemical reactions. However, these are special circumstances and cannot be seen under normal conditions. In short, in general, the chemical properties of 2% 2C5-difluoroethylbenzene are stable.
What are the production methods of 2,5-dichlorofluorobenzene?
2% 2C5-difluorobenzoic acid is an important intermediate in organic synthesis. The common preparation methods are as follows:
First, 2,5-dimethylbenzoic acid is used as the starting material, and fluorine atoms are introduced through halogenation reaction. This method requires specific halogenating reagents and suitable reaction conditions to ensure the precise introduction of fluorine atoms into the predetermined position. In the reaction, or with a fluorine-containing halogenating agent, under the action of a catalyst, a substitution reaction occurs with 2,5-dimethylbenzoic acid. However, this process requires fine control of the reaction temperature, time and reagent dosage to prevent side reactions from occurring and affecting the purity and yield of the product.
Second, 2,5-dichlorobenzoic acid is used as the raw material to achieve fluorination through halogen exchange reaction. This reaction requires a specific metal fluoride as a fluorine source, and under specific solvents and reaction conditions, chlorine atoms are replaced by fluorine atoms. This method requires strict reaction conditions, and appropriate reaction temperatures, pressures and catalysts are required to promote the smooth exchange of halogens. At the same time, effective separation and purification of products are required to remove unreacted raw materials and by-products.
Third, it is prepared by the coupling reaction of aryl boric acid and fluorohalogenated hydrocarbons. This method often requires transition metal catalysts, such as palladium catalysts, to catalyze the coupling of aryl boric acid and fluorohalogenated hydrocarbons to form carbon-fluorine bonds. During the reaction, the amount of catalyst, ligand selection, and the type of reaction solvent and base should be strictly controlled to improve the reaction efficiency and selectivity. The advantage of this method is that it can construct the target molecular structure more accurately, but the catalyst cost may be higher, and the reaction operation requirements are also high.
Fourth, the 2,5-difluorobenzoic acid structure is gradually constructed by multi-step reaction with benzene ring as the starting material. This approach is complicated and requires fine design of the reaction route and rational planning of the reaction sequence. Each step of the reaction must ensure high yield and purity to ensure the quality of the final product. However, the method is highly flexible and can modify and adjust the molecular structure according to actual needs.
What are the precautions for storing and transporting 2,5-dichlorofluorobenzene?
2% 2C5-difluoroethane is a volatile organic compound. When storing and transporting, it is necessary to pay attention to many key matters.
The first word is storage. First, it should be done in a cool and well-ventilated place. This is because 2% 2C5-difluoroethane is volatile, and in a high temperature environment, its vapor pressure rises, causing the internal pressure of the container to increase, and there is a risk of explosion. Therefore, placing it in a cool and ventilated place can effectively reduce the accumulation of steam and ensure its stability. Second, the storage container must be well sealed. If the seal is not good, 2% 2C5-difluoroethane is easy to evaporate and escape, causing material loss. Second, its vapor accumulates in the air, or causes fire, explosion and other hazards, and also pollutes the environment. Third, it should not be mixed with strong oxidants, strong acids, strong bases and other substances. 2% 2C5-difluoroethane has active chemical properties, comes into contact with the above substances, or causes violent chemical reactions, which can lead to dangerous accidents.
Second discussion on transportation. Transportation vehicles need to have perfect fire and explosion-proof facilities. 2% 2C5-difluoroethane vapor is flammable, and it is very easy to burn and explode in case of open flames and hot topics. Complete fire prevention and explosion-proof facilities can reduce the risk of accidents in the event of emergencies. During transportation, the speed of the vehicle should be stable and moderate, and violent operations such as sudden braking and sharp turns should be avoided. This compound generates static electricity under severe shaking, or due to internal friction and collision, and the static electricity accumulates to a certain extent, or triggers steam ignition, causing a disaster. In addition, transportation personnel also need professional training, familiar with the characteristics of 2% 2C5-difluoroethane and emergency treatment methods. Once abnormal conditions such as leaks occur during transportation, they can respond quickly and correctly to reduce hazards.
In conclusion, 2% 2C5-difluoroethane has strict requirements on environmental conditions, container status, material compatibility, transportation operation and personnel quality during storage and transportation. Only by adhering to various guidelines can the process be safe and secure.