1 Bromo 2 6 Dimethyl 4 Fluorobenzene
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
1-bromo-2,6-dimethyl-4-fluorobenzene
Chemical Formula C8H8BrF
Molar Mass 203.05 g/mol
Appearance Colorless to light yellow liquid (estimated)
Solubility In Water Insoluble (aromatic bromide and fluoride, non - polar)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (aromatic nature)
Chemical Formula C8H8BrF
Molecular Weight 203.05
Appearance Typically a colorless to light - colored liquid
Boiling Point Estimated based on similar compounds, around 190 - 210 °C
Density Approximately 1.4 - 1.6 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethyl acetate
Flash Point Caution: Flammable, flash point needs experimental determination
Vapor Pressure Low vapor pressure at room temperature
Odor May have a characteristic aromatic - halogenated odor
Chemical Formula C8H8BrF
Molar Mass 203.05 g/mol
Appearance Colorless to light yellow liquid
Boiling Point Approx. 195 - 200 °C
Density Approx. 1.47 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Approx. 77 °C
Odor Characteristic aromatic odor
FAQ

What is the main use of 1 - bromo - 2,6 - dimethyl - 4 - fluorobenzene

1-Bromo-2,6-dimethyl-4-fluorobenzene is also an organic compound. It has a wide range of main uses and is often a key raw material in the field of organic synthesis.

covers the delicacy of organic synthesis, which cares about the mutual reaction of various compounds to form the desired product. 1-Bromo-2,6-dimethyl-4-fluorobenzene, the structure of bromine, fluorine and methyl gives it unique reactivity. The bromine atom has a nucleophilic substitution activity check point, and can interact with many nucleophilic reagents, such as alcohols and amines, to introduce different functional groups and expand the structural diversity of the compound.

In the field of medicinal chemistry, this compound also has extraordinary uses. Drug development often relies on organic synthesis to create molecules with specific biological activities. 1-Bromo-2,6-dimethyl-4-fluorobenzene can be used as an intermediate for synthesizing drugs. After a series of reactions, a structure that fits the biological target is constructed, which is expected to develop new drugs for the treatment of various diseases.

Furthermore, in the field of materials science, it may be able to participate in the synthesis of polymer materials. By polymerizing with other monomers, it can give materials special properties, such as improving the thermal stability, mechanical properties or optical properties of materials.

In conclusion, although 1-bromo-2,6-dimethyl-4-fluorobenzene is an organic compound, it has indispensable and important uses in many fields such as organic synthesis, medicinal chemistry, and materials science. It is a substance worthy of in-depth investigation and application in chemical research and industrial production.

What are the physical properties of 1 - bromo - 2,6 - dimethyl - 4 - fluorobenzene

1-Bromo-2,6-dimethyl-4-fluorobenzene is one of the organic compounds. Its physical properties are particularly important, and it is related to the performance and application of this compound in various scenarios.

First of all, under normal conditions, 1-bromo-2,6-dimethyl-4-fluorobenzene is a colorless to light yellow liquid, and the appearance is clear. Its color is light, which is quite similar to the color of clear water, but it has a slightly yellowish luster, just like the early morning sun shining through tulle, hazy and characteristic.

As for the boiling point, it is about a specific temperature range. The value of the boiling point of this compound is determined by rigorous experiments. At this temperature, the substance changes from liquid to gaseous state, and the intermolecular forces change, from a relatively close arrangement to a free diffusion state. Its boiling point is of great significance for experimental operations such as distillation and separation and industrial production processes, so that the conversion of substances can be controlled to achieve the purpose of purification and purification.

Melting point is also one of the key physical properties. The melting point of 1-bromo-2,6-dimethyl-4-fluorobenzene is the critical temperature for the mutual transformation of its solid state and liquid state. When the outside temperature drops below the melting point, the substance gradually solidifies, the molecular movement slows down, and the arrangement tends to be orderly, forming a regular lattice structure; and when the temperature rises above the melting point, the lattice disintegrates, and the molecule regains the ability to move freely and converts to a liquid state.

In terms of density, 1-bromo-2,6-dimethyl-4-fluorobenzene has a certain density value. This value reflects the mass of the substance in a unit volume, which is like a scale for measuring its "thickness". By measuring the density, the stratification status of the compound when mixed with other substances can be determined, and it has important application value in chemical industry, analytical chemistry and other fields.

Solubility cannot be ignored. 1-Bromo-2,6-dimethyl-4-fluorobenzene exhibits different solubility in a variety of organic solvents. In some organic solvents, such as common ethanol, ether, etc., it can dissolve well, just like salt dissolves in water, uniformly disperses to form a uniform solution system; in water, its solubility is poor, and the two are difficult to blend, just like the incompatibility of oil and water. This property is closely related to molecular structure, polarity and other factors, and also affects its performance in different chemical reactions and practical applications.

What is the chemical synthesis method of 1 - bromo - 2,6 - dimethyl - 4 - fluorobenzene

To prepare 1-bromo-2,6-dimethyl-4-fluorobenzene, you can follow the following method. First, find a suitable starting material, preferably 2,6-dimethyl-4-fluoroaniline. This is because the amino group can guide the bromine atom to the specified position.

First convert 2,6-dimethyl-4-fluoroaniline into diazonium salt. Take an appropriate amount of 2,6-dimethyl-4-fluoroaniline, dissolve it in dilute hydrochloric acid, and cool it to a low temperature, generally 0-5 ° C. Slowly add sodium nitrite solution dropwise to maintain a low temperature, so that the amino group can be converted into a diazonium group to obtain a diazonium salt solution. This step needs to be handled with caution, because the diazonium salt is unstable.

Then the bromination reaction is carried out. Add cuprous bromide and hydrobromic acid to the above diazonium salt solution. The diazonium group is replaced by a bromine atom to generate 1-bromo-2,6-dimethyl-4-fluorobenzene. This reaction follows the Sandmeier reaction mechanism. After the reaction is completed, the product is purified by conventional separation methods, such as extraction, distillation, column chromatography, etc. When extracting, a suitable organic solvent is selected to dissolve the product into the organic phase and separate it from the impurities. Distillation can further purify according to the difference between the boiling points of the product and the impurities. Pure 1-bromo-2,6-dimethyl-4-fluorobenzene was obtained by column chromatography according to adsorption principle.

1 - bromo - 2,6 - dimethyl - 4 - fluorobenzene in the storage and transport of any precautions

1 + -Bromo-2,6-dimethyl-4-fluorobenzene is an organic compound. When storing and transporting, many key matters need to be paid attention to.

Safety is the first priority. This compound may be toxic, irritating or flammable, and must be protected when exposed. Handlers should wear suitable protective clothing, including protective clothing, gloves and goggles to prevent skin-to-eye contact. If in a poorly ventilated area, a gas mask should also be worn to avoid inhalation of volatile gases.

This is the storage condition. It should be placed in a cool, dry and well ventilated place, away from fire and heat sources. Due to its flammability, in case of open flames, hot topics or causing combustion, fireworks are strictly prohibited in storage places. It needs to be stored separately from oxidants, acids, etc. to prevent reactions. Due to its active chemical properties, it can come into contact with certain substances or cause dangerous reactions.

Furthermore, transportation should not be ignored. Before transportation, ensure that the packaging is complete and the loading is safe. The containers used for transportation must be able to withstand certain pressure and vibration to prevent leakage. During transportation, pay close attention to changes in temperature and humidity to avoid extreme conditions. Transportation vehicles should be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment. If there is a leak, it can be responded to in time.

In addition, label identification is essential. Storage containers and transportation packages should be clearly marked with information such as compound names, properties, and hazard warnings, so that contacts can see at a glance and take correct protection and treatment measures.

In conclusion, the storage and transportation of 1 + -bromo-2,6-dimethyl-4-fluorobenzene requires strict compliance with relevant regulations and operating procedures, with a high priority on safety, accident prevention, and personnel and environmental safety.

Effects of 1 - bromo - 2,6 - dimethyl - 4 - fluorobenzene on the environment and human health

1 + -Bromo-2,6-dimethyl-4-fluorobenzene has a significant impact on the environment and human health. This compound is toxic to a certain extent. If it enters the natural environment, it may have various effects.

In the soil, it may be difficult to degrade and gradually accumulate in the soil, causing soil quality to deteriorate, affecting plant roots to absorb nutrients, hindering plant growth, or reducing crop yield. If it flows into the water body, it will be a sewage source. Aquatic organisms such as fish, shrimp and shellfish are exposed to this poison, or their physiological functions are damaged, resulting in the loss of the population and destroying the aquatic ecological balance.

As for human health, if people ingest it through breathing, diet or skin contact, it may damage their health. In the respiratory system, or irritate the respiratory tract, causing cough, asthma, long-term exposure, or increasing the risk of respiratory diseases. Enter the digestive system, or harm the intestinal and gastric mucosa, causing nausea, vomiting, and abdominal pain. What's more, it may be potentially carcinogenic, long-term exposure will increase the chance of cancer. And it also affects the nervous system, causing dizziness, fatigue, insomnia, and interfering with the normal operation of the nervous system.

Therefore, the compounds of 1 + -bromo-2,6-dimethyl-4-fluorobenzene should be treated with caution and strengthened control to ensure a beautiful environment and protect human health.