Name | 1 - bromo - 2,3,5 - trifluorobenzene |
Molecular Formula | C6H2BrF3 |
Molecular Weight | 225.98 |
Appearance | Colorless to light yellow liquid |
Boiling Point | 149 - 150 °C |
Melting Point | N/A |
Density | 1.745 g/cm³ |
Solubility | Insoluble in water, soluble in organic solvents |
Flash Point | 46 °C |
Refractive Index | 1.463 - 1.465 |
Vapor Pressure | N/A |
Stability | Stable under normal conditions |
Chemical Formula | C6H2BrF3 |
Molecular Weight | 225.98 |
Appearance | Colorless to light yellow liquid |
Boiling Point | 163 - 164 °C |
Melting Point | N/A |
Density | 1.745 g/mL at 25 °C |
Vapor Pressure | N/A |
Water Solubility | Insoluble |
Flash Point | 57 °C |
Refractive Index | 1.472 |
Chemical Formula | C6H2BrF3 |
Appearance | Colorless to light yellow liquid |
Boiling Point | 155 - 157 °C |
Melting Point | N/A |
Density | 1.73 g/cm³ |
Solubility | Insoluble in water, soluble in organic solvents like ethanol, ether |
Flash Point | 49 °C |
Vapor Pressure | N/A |
Refractive Index | 1.475 |
What are the main uses of 1-bromo-2,3,5-trifluorobenzene?
1-2,3,5-trichloride, its main use is broad, and it is useful in many domains.
In terms of fertility, 1-2,3,5-trichloride has a certain utility value. The multi-chemical components contained in its plants have been studied and can be used to solve some common diseases such as arthralgia, bruises, etc. In ancient times, the plant also has a related nature, taste is slightly bitter, and can be used to promote blood circulation and relieve pain. In case of bruises and twists, the product can be applied externally, which can effectively relieve pain.
In the field, this plant also has its own special characteristics. 1 - 2, 3, 5 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - 3 - At the same time, it also plays a certain role in maintaining water and soil. Its root system can fix the soil and prevent soil erosion.
Therefore, 1-2, 3, 5-3 are essential in terms of soil conservation, water conservation, and other aspects. It is the precious source of nature.
What are the physical properties of 1-bromo-2,3,5-trifluorobenzene?
1-% Dian-2,3,5-tribromophenol is an organic compound with the following physical properties:
It is a white to light yellow fine powder at room temperature and pressure, with a fine appearance. The melting point of this substance is quite clear, about 95-96 ° C. The melting point is the critical temperature at which the substance changes from solid to liquid. At this temperature, the molecule obtains enough energy to overcome the lattice binding and can move freely. The melting point of 1-% Dian-2,3,5-tribromophenol is in this range, indicating that the intermolecular force is moderate.
1-% Dian-2,3,5-tribromophenol is insoluble in water, because water is a highly polar solvent, while 1-% Dian-2,3,5-tribromophenol molecules have relatively weak polarities. According to the principle of "similarity and miscibility", the polarity difference leads to poor miscibility between the two. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc. Organic solvents are mostly weakly polar or non-polar, and have similar polarity to 1-% Dian-2,3,5-tribromophenol molecules, so they are miscible. For example, ethanol, whose molecules have both polar hydroxyl and non-polar ethyl groups, can be combined with 1-% Dian-2,3,5-tribromophenol through intermolecular forces to achieve dissolution. The density of
1-% Ydian-2,3,5-tribromophenol is higher than that of water. If it is placed in water, it will sink to the bottom of the water. Density, as the mass per unit volume of a substance, reflects the compactness of the internal structure of the substance. The atomic weight of 1-% Ydian-2,3,5-tribromophenol is large due to the presence of bromine atoms in the molecular structure, which increases the mass per unit volume and has a density greater than that of water.
1-% Ydian-2,3,5-tribromophenol is relatively stable at room temperature, but it may decompose under extreme conditions such as hot topics and open flames. And because of its bromine content, harmful gases containing bromine will be produced during combustion, which is harmful to the environment and personal safety.
What are the synthesis methods of 1-bromo-2,3,5-trifluorobenzene?
To prepare 1-bromo-2,3,5-trifluorobenzene, the method is as follows:
First, 2,3,5-trifluorobenzene is used as the starting material, and is prepared by diazotization and bromination. First, dissolve 2,3,5-trifluorobenzene in an appropriate amount of strong acid (such as hydrochloric acid or sulfuric acid), cool to a low temperature, generally 0-5 ° C, slowly add sodium nitrite solution, and perform a diazotization reaction to obtain 2,3,5-trifluorobenzene diazonium salt. After adding the diazonium salt solution to the hydrobromic acid solution containing cuprous bromide, heating, through the Sandmeyer reaction, the diazonium group is replaced by the bromine atom, and then 1-bromo-2,3,5-trifluorobenzene is obtained. This step is clearer and the yield is considerable.
2,3,5-trifluorobenzene boronic acid can also be reacted with brominating reagents. 2,3,5-trifluorobenzene boronic acid is reacted with brominating agents such as copper bromide and potassium persulfate in suitable solvents (such as dichloromethane, N, N-dimethylformamide, etc.) in the presence of bases (such as potassium carbonate, sodium carbonate). This is based on the palladium-catalyzed or palladium-free cross-coupling reaction mechanism, which can replace the boric acid group with a bromine atom to obtain the target product. The advantage is that the reaction conditions are relatively mild and environmentally friendly.
Furthermore, it can be prepared from 2,3,5-trifluorobrombenzene through halogen exchange reaction. Using 2,3,5-trifluorobrombenzene as raw material, with metal fluoride (such as potassium fluoride), in a high boiling point polar solvent (such as dimethyl sulfoxide, N-methylpyrrolidone), add a phase transfer catalyst (such as tetrabutylammonium bromide), and react at high temperature. Although the starting materials are more readily available in this way, halogen exchange reactions sometimes require severe conditions, and selectivity may be insufficient, requiring fine regulation of reaction parameters.
What are the precautions for storing and transporting 1-bromo-2,3,5-trifluorobenzene?
1-2,3,5-Three-year-old musk deer, there are things that should be paid attention to during the process of storage.
This thing is also very weak in nature, and it is easy to be damaged when exposed to light. Therefore, if it is not stored, it must be damaged, dry and good, and it will be a source of fire and energy to prevent it from being damaged by heat. If it is exposed to sunlight, or a high environment, it is feared that its active ingredients will dissipate, resulting in great efficacy.
Furthermore, on the way, the package will be dense. Because of its high value and easy to be damaged, it will be broken if there is a little carelessness. The material of the package should be solid and have the ability to prevent collision and shock.
Also, this kind of item may be toxic or special, and it should be carried out in accordance with the law. Those who work hard must receive the necessary information, and they must not be wantonly. Where it is stored, there is also a clear warning, so that others can know the danger, so that they will not be affected.
And where it exists, the degree is also important. If the degree is high, it is easy to produce and rot; if the degree is low, it may cause it to crack and melt. Therefore, it is necessary to control the degree and ensure the quality of its products.
Therefore, 1-2,3,5-three musk musk musk in the process of storage, light, temperature, packaging, moving temperature, temperature and temperature, all need to be careful to ensure its safety.
What are the effects of 1-bromo-2,3,5-trifluorobenzene on the environment and human health?
1-Naphthalene-2,3,5-trisulfonic acid. Although the influence of this substance on the environment and human health has not been discussed in ancient times, its outline can also be obtained based on today's scientific understanding.
1-Naphthalene-2,3,5-trisulfonic acid If scattered in nature, there is a risk of contamination in water bodies and soils. It enters the water body, or causes the water quality to deteriorate, and the environment on which aquatic organisms depend for survival is disrupted. Aquatic plants may be impaired by photosynthesis, and their growth is sluggish; aquatic animals may be disrupted by sensory physiology, reproduction is trapped, and even populations wither. For soil, or change its physicochemical properties, so that the soil fertility is unbalanced, resulting in difficult vegetation growth and broken ecological chains.
As for human health, if 1-naphthalene-2,3,5-trisulfonic acid enters the body through the mouth, nose or skin, it may be a serious disaster. Entering the body through the respiratory tract, or irritating the respiratory mucosa, causing cough, asthma, long-term contact, or increasing the risk of lung disease. If exposed to the skin, or cause skin allergies, itching, redness and swelling, damage the skin barrier. If eaten by mistake, it may hurt the stomach, cause nausea, vomiting, abdominal pain, and even endanger the viscera.
Furthermore, this substance may have potential genetic toxicity and carcinogenicity. Although this was not said in ancient times, modern research often shows that compounds with such structures can disturb the genetic material of human cells, cause gene mutation, accumulate over time, or induce cancer.
Therefore, although the ancients did not specify the harm of 1-naphthalene-2,3,5-trisulfonic acid, with the wisdom of today's science, it is necessary to be careful to prevent it from causing harm to the environment and human health.