1 4 Ethylfluorobenzene
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
1,4-ethylfluorobenzene
Chemical Formula C8H9F
Molecular Weight 124.16
Appearance Colorless liquid
Odor Aromatic odor
Boiling Point 154 - 156 °C
Density 0.992 g/cm³ at 25 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 41 °C
Refractive Index 1.485 - 1.487 at 20 °C
Chemical Formula C8H9F
Molecular Weight 124.16
Appearance Colorless liquid
Boiling Point 157 - 158 °C
Density 0.989 g/cm³
Solubility In Water Insoluble
Flash Point 40 °C
Odor Aromatic odor
Refractive Index 1.488
Chemical Formula C8H9F
Molar Mass 124.155 g/mol
Appearance Colorless liquid
Boiling Point 157 - 158 °C
Melting Point -50 °C
Density 0.995 g/cm³
Flash Point 39 °C
Solubility In Water Insoluble
Vapor Pressure 1.74 mmHg at 25 °C
Refractive Index 1.486 (20 °C)
FAQ

What are the main uses of 4-ethylfluorobenzene?

1% 2C4-ethylfluorobenzene is 1,4-ethylfluorobenzene, which is widely used.

In the field of organic synthesis, it is a key raw material. Chemists often use this as a starting material to prepare complex organic compounds through many chemical reactions, such as substitution reactions, addition reactions, etc. Because of the ethyl and fluorine atoms on the benzene ring, which give unique chemical activity and spatial structure, hydrogen atoms at other positions on the benzene ring can be replaced by various functional groups through substitution reactions, and then organic molecules with specific properties and functions can be synthesized, which is of great significance in pharmaceutical chemistry, materials science, etc.

In drug development, 1,4-ethylfluorobenzene also plays an important role. Due to its special structure, the synthesized compounds containing this structure may have unique biological activities and can interact with specific targets in vivo. By modifying and optimizing its structure, innovative drugs with good efficacy and few side effects can be obtained.

In the field of materials science, organic materials synthesized from this raw material may have special electrical and optical properties. For example, synthetic polymer materials, or due to the introduction of 1,4-ethylfluorobenzene structural units, exhibit good fluorescence properties, and can be used as luminescent materials in the field of optoelectronic materials, used in organic Light Emitting Diode and other devices.

Overall, 1,4-ethylfluorobenzene has important uses in many fields such as organic synthesis, drug development, and materials science, and plays a key role in promoting the development of related fields.

What are the physical properties of 4-ethylfluorobenzene?

1% 2C4-ethylfluorobenzene is 1,4-ethylfluorobenzene. Its physical properties are as follows:

1,4-ethylfluorobenzene, an organic compound, usually in a liquid state at room temperature and pressure. Looking at its color, it is almost colorless and transparent, just like clear water, without obvious variegation, showing a pure state.

Smell its smell, which has a special aromatic smell. Although this smell has a certain volatility, it is very different from the common pungent and unpleasant smell. Unlike many chemicals with strong pungent smell, its fragrance is more unique.

When it comes to density, the density of 1,4-ethylfluorobenzene is less than that of water. If it is placed in the same container as water, it can be seen that it floats on the surface of the water, just like a light boat on the lake surface, and it is distinct.

Its boiling point is about a certain range. Under specific pressure conditions, when the corresponding temperature is reached, 1,4-ethylfluorobenzene will change from liquid to gaseous. The characteristics of this boiling point are of crucial significance for its separation and purification processes in chemical production.

As for the melting point, when the temperature drops to a specific value, 1,4-ethylfluorobenzene will solidify from liquid to solid, just like water freezes when cold. Knowing its melting point, during storage and transportation, appropriate measures can be taken according to temperature conditions to ensure the stability of its physical state.

In addition, 1,4-ethylfluorobenzene is slightly soluble in water, like oil droplets entering water, and it is difficult to melt with water. This solubility characteristic also determines its behavior in some reaction systems and separation processes. Among organic solvents, such as common ethanol, ether, etc., 1,4-ethylfluorobenzene has good solubility and can be mixed with these organic solvents to form a uniform solution system.

Is the chemical properties of 4-ethylfluorobenzene stable?

1% 2C4-ethylfluorobenzene is 1,4-ethylfluorobenzene, and its chemical properties are still stable. This compound contains a benzene ring. The benzene ring has a conjugated system, which is stable in structure and difficult to react under general conditions. And although the fluorine atom is electron-absorbing, it forms a p-π conjugate after being connected to the benzene ring, which stabilizes the molecule to a certain extent. Ethyl is a power supply group, which has an effect on the electron cloud density of the benzene ring, but does not cause a significant increase in molecular activity as a whole.

Usually, 1,4-ethylfluorobenzene can maintain a relatively stable state at room temperature and pressure and in the absence of special catalysts and reactants. However, it can still react under extreme conditions such as high temperature, strong oxidizing agent, strong acid and strong base. For example, at high temperatures, the substitution reaction on the benzene ring may occur; in case of strong oxidants, the side chain ethyl of the benzene ring may be oxidized. In general, under common mild conditions, the chemical properties of 1,4-ethylfluorobenzene are relatively stable, but under special conditions, its stability will be affected and chemical changes will occur.

1. What are the production methods of 4-ethylfluorobenzene?

1% 2C4 -ethylfluorobenzene is 1,4-ethylfluorobenzene. The preparation method is as follows:

First, p-fluorobenzene can be used. First, p-fluorobenzene is reacted with magnesium chips in a solvent such as anhydrous ether to make Grignard's reagent. This reaction needs to be carried out in a dry and oxygen-free environment. Due to the high activity of Grignard's reagent, it is easy to react in contact with water or oxygen. After that, bromoethane is added to the reaction system, and Grignard's reagent undergoes a nucleophilic substitution reaction with bromoethane to generate 1,4-ethylfluorobenzene. After the reaction is completed, the product is separated and purified by distillation, extraction and other means.

Second, p-fluorobenz First, a suitable reducing agent, such as sodium borohydride, is used to reduce the carbonyl group of p-fluorophenyl ketone to an alcoholic hydroxyl group to obtain p-fluorophenyl ethanol. The reduction reaction is usually carried out in an alcohol solvent, and the reaction conditions are relatively mild. Then, the p-fluorophenyl ethanol is halogenated, and a halogenating agent such as phosphorus tribromide can be selected to convert the hydroxyl group into a bromine atom to generate p-fluorobromophenethane. Finally, through the dehalogenation reaction, under the action of strong bases such as sodium ethanol, the hydrogen bromide is eliminated to form 1,4-ethylfluorobenzene. The product also needs to be separated and purified to obtain pure 1,4-ethylfluorobenzene.

Third, start with p-fluoroaniline. First, p-fluoroaniline and sodium nitrite are diazotized in a hydrochloric acid solution to form diazonium salts. This reaction requires strict control of the temperature in the low temperature range to prevent the decomposition of diazonium salts. Subsequently, reducing agents such as ethanol are added to replace the diazonium group with hydrogen atoms to obtain p-fluorobenzene. Then, in the presence of catalysts such as aluminum trichloride, p-fluorobenzene and bromoethane are alkylated by Fu-g to form 1,4-ethylfluorobenzene. After the reaction, separation and purification operations are carried out to obtain the final product.

1, 4-ethylfluorobenzene What are the precautions in storage and transportation?

1% 2C4-ethylfluorobenzene is 1,4-ethylfluorobenzene. Many things need to be paid attention to when storing and transporting this substance.

Let's talk about storage first. Because it has a certain chemical activity, it should be dry, cool and well ventilated. If placed in a humid place, water vapor may cause hydrolysis and other reactions, which will damage its purity and quality. Temperature is also critical. Excessive temperature may increase its volatilization and even cause safety accidents. Generally, it should be controlled at room temperature or slightly lower temperature. Furthermore, it should be kept away from fire and heat sources. Because it may be flammable, it is easy to catch fire and burn in case of open flames and hot topics, resulting in disasters. In addition, the storage container must be well sealed to prevent it from evaporating and escaping, polluting the environment, and avoiding reactions with oxygen, moisture and other components in the air.

As for transportation, the first heavy packaging. Packaging materials must be strong and well sealed, able to withstand certain external shocks and bumps, so as not to break and leak during transportation. Handle with care during loading and unloading to avoid package damage caused by brutal operation. Transportation vehicles also need compliance, and should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. During transportation, closely monitor temperature and humidity, drive according to the established route, avoid densely populated areas and environmentally sensitive areas, in case of leakage, causing serious harm to the public and the environment.

In short, the storage and transportation of 1,4-ethylfluorobenzene should be handled with caution, and relevant norms and standards should be strictly adhered to to to ensure safety and avoid accidents.