Chemical Formula | C8H3FN2 |
Molar Mass | 146.12 g/mol |
Appearance | Solid |
Color | White to off - white |
Odor | Typical organic compound odor |
Melting Point | 63 - 66 °C |
Boiling Point | 240 - 242 °C |
Density | 1.31 g/cm³ |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
Chemical Formula | C8H3FN2 |
Molecular Weight | 146.12 |
Appearance | Solid (usually white to off - white) |
Melting Point | 124 - 126 °C |
Density | Data may vary, typically in the range of organic solids |
Solubility In Water | Low solubility in water |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
Stability | Stable under normal conditions, but reactive towards strong oxidizing and reducing agents |
Odor | Odorless or very faint odor |
Chemical Formula | C8H3FN2 |
Molecular Weight | 146.12 g/mol |
Appearance | Solid (usually a white to off - white powder) |
Melting Point | 69 - 73 °C |
Boiling Point | 263 - 265 °C |
Density | 1.32 g/cm³ |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
Flash Point | 112.7 °C |
Vapor Pressure | Low at room temperature |
Stability | Stable under normal conditions |
What are the main uses of 1,2-dicyano-4-fluorobenzene?
1% 2C2-diethylamino-4-ethoxybenzene has a wide range of main uses. In the field of medicine, it is often a key intermediate for the preparation of many drugs. Due to its unique chemical structure, it can endow drugs with specific pharmacological activities and properties, which helps to improve drug efficacy and optimize drug metabolism. For example, in the synthesis of some cardiovascular disease treatment drugs, this compound can construct the core structure of the drug through specific reaction steps, and then regulate the physiological function of the cardiovascular system.
In the dye industry, it also plays an important role. Due to its structure containing chromophore and chromophore, it can be chemically modified to regulate its color and dyeing properties. It is used to synthesize various dyes with bright colors and good fastness. It is widely used in textiles, printing and dyeing and other fields to impart rich colors to fabrics.
In the field of organic synthesis, as an important raw material and intermediate, it participates in the synthesis of a variety of complex organic compounds. With its functional group characteristics, substitution, addition, condensation and many other reactions can occur, laying the foundation for the synthesis of organic materials with special structures and functions, such as some optoelectronic materials, functional polymer materials, etc. With its diverse chemical properties, this compound plays an indispensable role in many fields such as medicine, dyes, and organic synthesis, and is of great significance to promote the development of related industries.
What are the physical properties of 1,2-dicyano-4-fluorobenzene?
1% 2C2-diethylamino-4-ethoxybenzene is a kind of organic compound. Its physical properties have the following characteristics:
Under normal temperature and pressure, it is mostly colorless to light yellow liquid, with uniform and clear texture. This appearance is easy to intuitively identify, and in many chemical scenes, it can be preliminarily judged whether its state is normal.
Smell its smell, often emitting a special aromatic smell, but this smell is not simply pleasant and fragrant, or has a certain irritation. When handling this substance, do not ignore its potential irritation due to its aroma, so as not to cause damage to the respiratory tract.
As for the melting boiling point, the melting point is quite low, and it is liquid at room temperature; the boiling point is relatively high, about a certain temperature range (the specific value is subject to accurate measurement). This melting boiling point characteristic is of great significance in the process of separation, purification and storage. When heating and separating, the pure product can be obtained by distillation and other means according to the difference in boiling point; when storing, the ambient temperature should be taken into account to prevent it from vaporizing and escaping due to excessive temperature.
In terms of solubility, it shows good solubility in organic solvents such as ethanol and ether, and can dissolve with each other to form a uniform solution. However, the solubility in water is not good, and it can only be slightly soluble. This difference in solubility can be used in chemical synthesis, extraction and other operations to select suitable solvents to achieve effective separation and reaction. The density of
is slightly smaller than that of water. If mixed with water, it will float on the water surface. This density characteristic can be used as an important basis for judgment when it comes to the operation of separation of aqueous and organic phases, and it is convenient for subsequent processing through stratification phenomenon.
1% 2C2-diethylamino-4-ethoxylbenzene The physical properties of
1% 2C2-diethylamino-4-ethoxylbenzene are of critical significance in chemical production, chemical research and other fields. Relevant practitioners must know in detail before they can properly use and handle this substance.
What are the chemical properties of 1,2-dicyano-4-fluorobenzene?
1% 2C2-diethylamino-4-ethoxylbenzene, this substance is an organic compound with unique chemical properties. Its molecules contain diethylamino and ethoxy groups, which have a great influence on its properties.
From the perspective of physical properties, most of them are solids or liquids, with specific melting points and boiling points. Due to the interaction of heteroatoms such as nitrogen and oxygen with other organic molecules or hydrogen bonds, the melting boiling points are different. Its solubility is related to molecular polarity. Diethylamino and ethoxy increase the molecular polarity, so it has a certain solubility in polar solvents such as ethanol and acetone.
Chemically, the benzene ring is an electron-rich system, which is aromatic and prone to electrophilic substitution reactions. If under appropriate conditions, it can react with halogenated hydrocarbons, acyl halides and other electrophilic reagents, and introduce a substituent at a specific position in the benzene ring. The nitrogen atom in the diethylamino group has a lone pair electron, which has a certain alkalinity and can react with acids to form salts. This property may affect the solubility and reactivity of the compound. The oxygen atom in the ethoxy group can participate in some nucleophilic substitution reactions. In case of strong nucleophilic reagents, the ethoxy group may be substituted.
This compound has a wide range of uses in the field of organic synthesis. It can be used as an intermediate to synthesize biologically active compounds, such as certain drugs and dyes. Because of its special structure and properties, or endow the product with specific functions and characteristics.
What are the synthesis methods of 1,2-dicyano-4-fluorobenzene?
There are many ways to synthesize 1% 2C2-diethylamino-4-chlorobenzene. Here are some common methods for your reference.
First, 4-chloroaniline can be started. 4-chloroaniline is salted with sulfuric acid, and then reacted with acetic anhydride at a suitable temperature and pressure to obtain an acetylated product. Next, the acetylated product is alkylated with halogenated ethane in an alkaline environment, such as an alcohol solution of potassium carbonate. After alkylation, hydrolysis with acid or base, and removal of acetyl groups, 1% 2C2-diethylamino-4-chlorobenzene can be obtained. The key to this path lies in the control of the conditions of each step of the reaction. Temperature, pH and the proportion of the reactants are all related to the yield and purity of the product.
Second, 4-chloroanisole is used as the raw material. First, it is aminated with ethylamine under high temperature and pressure under the help of a catalyst, such as a copper catalyst, to obtain 4-ethylamino anisole. Then, haloethane is alkylated again to obtain diethylamino anisole. Finally, the target product is demethylated with a suitable reagent, such as hydroiodic acid. This method requires attention to the activity and selectivity of the amination reaction, as well as the side reactions of the demethylation step.
Third, start with 4-chlorobenzaldehyde. Shilling it condensed with ethylamine to form an imine intermediate. This imine intermediate is reduced with a reducing agent such as sodium borohydride or lithium aluminum hydride to obtain 4-ethylaminobenzyl alcohol. Then, the hydroxyl group is converted into a chlorine atom with a halogenated reagent, such as thionyl chloride, and the alkylation reaction with halogenated ethane is carried out again, and the final product is 1% 2C2-diethylamino-4-chlorobenzene. In this approach, the condensation and reduction steps must be handled carefully to ensure the smooth progress of the reaction and the quality of the product.
Synthesis methods have advantages and disadvantages. It is necessary to make a careful choice according to many factors such as the availability of raw materials, cost considerations, difficulty of reaction and purity of the product. In this way, the goal can be achieved smoothly on the path of synthesis.
What are the precautions for storing and transporting 1,2-dicyano-4-fluorobenzene?
1% 2C2-diethylamino-4-hydroxyquinoline must be paid attention to during storage and transportation.
Its properties may be unstable and sensitive to environmental conditions. When storing, choose a dry, cool and well-ventilated place. If the environment is humid, it may be susceptible to moisture and deterioration, affecting quality and effectiveness. Temperature is also crucial. Excessive temperature may cause components to decompose and reduce activity, so it should be controlled within a specific temperature range.
When transporting, ensure that the packaging is tight and stable. This substance may be dangerous. If the packaging is damaged, there is a risk of leakage, which may not only damage itself, but also endanger the safety of transporters and the surrounding environment. And during transportation, severe vibrations and collisions should be avoided to prevent damage to the packaging, and to avoid mixing with other chemicals to avoid chemical reactions.
Furthermore, due to the special chemical properties of 1% 2C2-diethylamino-4-hydroxyquinoline, storage and transportation must follow relevant regulations and standards. Relevant personnel should be familiar with its characteristics and safety operating procedures, and act in accordance with the regulations to ensure the safety of the entire storage and transportation process, prevent accidents, and maintain personnel safety and environmental stability.