What is the chemical structure of (Z) - (2,4-Difluorophenyl) piperidin-4-ylmethanone oxime monohydrochloride

(Z) - (2,4-difluorophenyl) piperidine-4-methylketoxime monohydrochloride, which is a kind of organic compound. To clarify its chemical structure, when analyzing its various components.

" (Z) ", it shows that the compound has a specific spatial configuration, that is, the cis configuration, which is related to the arrangement of atoms in the molecule in space.

" (2,4-difluorophenyl) ", which is an aromatic hydrocarbon group, above the phenyl group, there are fluorine atoms at the 2nd and 4th positions. Phenyl is a six-membered cyclic unsaturated hydrocarbon group with unique electron cloud distribution and chemical activity. The introduction of fluorine atoms significantly changes the physical and chemical properties of compounds. Due to its strong electronegativity, it can affect the polarity and lipophilicity of molecules.

"Piperidine-4-ylmethanone" part, piperidine is a six-membered saturated heterocycle containing nitrogen, and is connected to methanone (-CO -) at the 4 position. The piperidine ring imparts certain rigidity and alkalinity to the molecule. Methanone groups are functional groups with carbonyl groups, which have unique reactivity and can participate in various organic reactions, such as nucleophilic addition.

"Oxime", a functional group obtained by the reaction of aldons or ketones with hydroxylamines, with a structure of = N-OH. In this compound, the oxime group is attached to the carbonyl group of piperidine-4-ylmethanone, which changes the electron cloud density and reactivity of the carbonyl group.

"Monohydrochloride" indicates that the compound forms a salt with one molecule of hydrogen chloride. After salt formation, the water solubility of the compound is greatly increased, and its physical and chemical properties also change significantly. In the field of medicinal chemistry, salt formation is often used to improve the solubility and stability of drugs.

In summary, the chemical structure of (Z) - (2,4-difluorophenyl) piperidine-4-yl ketoxime monohydrochloride is composed of phenyl, piperidine ring, ketoxime and hydrochloride moieties of specific configurations, and the interaction of each moiety endows the compound with unique chemical and physical properties.

What are the main uses of (Z) - (2,4-Difluorophenyl) piperidin-4-ylmethanone oxime monohydrochloride

(Z) - (2,4-difluorophenyl) piperidine-4-methylketoxime monohydrochloride, an important organic compound, has its uses in many fields.

In the field of medicinal chemistry, it is often used as a key intermediate. The research and development of many new drugs requires this as the starting material, through a series of delicate chemical reactions, to construct molecular structures with specific biological activities. By modifying and modifying its chemical structure, therapeutic drugs for specific diseases can be developed, such as anti-nervous system diseases, anti-cancer drugs, etc. Due to its unique chemical structure and properties, it can be combined with specific targets in organisms to exert pharmacological effects.

In the field of organic synthesis chemistry, (Z) - (2,4-difluorophenyl) piperidine-4-methyl ketoxime monohydrochloride also plays an important role. It can provide a unique structural unit for organic synthesis reactions, helping synthetic chemists to prepare complex and novel organic compounds. Whether it is to construct nitrogen-containing heterocyclic compounds or to realize the transformation of specific functional groups, it can be used as a basis for reactions to expand the variety and structure of organic compounds.

It may also have potential applications in the field of materials science. After specific treatment and modification, it may endow materials with special physical and chemical properties, such as optical properties, electrical properties, etc. Functional materials developed on the basis of this compound may be applied to frontier scientific and technological fields such as optoelectronic devices and sensors, injecting new vitality into the development of materials science.

In short, (Z) - (2,4-difluorophenyl) piperidine-4-methylketoxime monohydrochloride plays an indispensable role in many fields such as medicine, organic synthesis and materials science, and promotes the continuous progress of research and technology in various fields.

What are the physical properties of (Z) - (2,4-Difluorophenyl) piperidin-4-ylmethanone oxime monohydrochloride

(Z) - (2,4-difluorophenyl) piperidine-4-methylketoxime monohydrochloride, this is an organic compound. Its physical properties are unique, let me tell them one by one.

Looking at its appearance, under room temperature and pressure, it is mostly white to white solid powder with fine texture. The melting point of this compound is within a specific range, but the exact value will vary slightly due to subtle differences in experimental conditions. The determination of melting point is of great significance in identification and purity determination.

Solubility is also an important physical property. In common organic solvents, such as methanol, ethanol and other polar organic solvents, this compound exhibits a certain solubility and can partially dissolve to form a homogeneous solution. This characteristic makes it possible to select suitable solvents for separation, purification and reaction operations in related chemical operations. In non-polar organic solvents such as n-hexane and toluene, its solubility is poor, and it mostly exists in solid form, making it difficult to blend with solvents.

Furthermore, the density of the compound is relatively stable. Although the specific value will change slightly with temperature, pressure and other conditions, in conventional experiments and application environments, the density can be used as a fixed physical parameter to help calculate the amount of material and the volume occupied in the reaction system.

Its stability is also worthy of attention. Under dry, normal temperature and no special chemical reaction conditions, the compound can maintain a relatively stable chemical structure and is not prone to spontaneous decomposition or other chemical changes. However, if exposed to extreme conditions such as high temperature, high humidity or strong acid and alkali, its chemical structure may be damaged, which in turn affects its physical properties and chemical activities.

In summary, the physical properties of (Z) - (2,4-difluorophenyl) piperidine-4-methyl ketoxime monohydrochloride play a key role in many fields such as chemical synthesis and drug development, and have a profound impact on related experimental operations and practical applications.

What is the synthesis method of (Z) - (2,4-Difluorophenyl) piperidin-4-ylmethanone oxime monohydrochloride

To prepare (Z) - (2,4-difluorophenyl) piperidine-4-methyl ketone oxime monohydrochloride, the method is as follows.

First take an appropriate amount of (2,4-difluorophenyl) piperidine-4-methyl ketone and place it in a clean reaction vessel. Add a suitable oximizing agent, often hydroxylamine hydrochloride, etc., and add an appropriate amount of base, such as sodium acetate, to help the reaction proceed. Control the reaction temperature and duration, the temperature may be maintained in a moderate range, such as between 40 and 60 degrees Celsius. After several times of reaction, the oximization reaction is formed to obtain (Z) - (2,4-difluorophenyl) piperidine-4-methyl ketoxime.

Then, the resulting (Z) - (2,4-difluorophenyl) piperidine-4-methyl ketoxime is placed in another reaction instrument. Slowly add an appropriate amount of hydrochloric acid solution dropwise, and the rate of dropwise acceleration should be slow to prevent the reaction from being overly dramatic. After the dropwise addition is completed, heat up appropriately, or until 50 to 70 degrees Celsius, and continue the reaction for a period of time to make the salt-forming reaction sufficient. After the reaction is completed, pure (Z) - (2,4-difluorophenyl) piperidine-4-methylketoxime monohydrochloride can be obtained by cooling, crystallization, filtration, washing, drying and other operations.

The key to this preparation method lies in the precise control of the reaction conditions in each step and the proper preparation of the amount of reagents, so that high-purity products can be obtained.

What is the price range of (Z) - (2,4-Difluorophenyl) piperidin-4-ylmethanone oxime monohydrochloride in the market?

I am looking at the price range of " (Z) - (2,4-difluorophenyl) piperidine-4-methylketoxime monohydrochloride" you are inquiring about on the market. However, the price of this product on the market is difficult to say exactly. The price often varies due to many factors.

First, the cost of production is also. The price of raw materials and the difficulty of preparation will affect its cost. If the raw materials are rare and difficult to find, or the preparation process is complicated, and many steps and special reagents are required, the cost will be high, and its selling price will also rise accordingly.

Second, the relationship between supply and demand. If the market demand for this product is strong and the supply is limited, the price will tend to rise; conversely, if the supply exceeds the demand, the price may decline.

Third, the difference in quality. Produced by different manufacturers, the quality may be different. High quality, or due to strict quality control and advanced production technology, the price is different from that of low quality.

Fourth, the sales area and channel also have an impact. In prosperous cities and specific sales platforms, the price may be different due to operating costs, etc.

In summary, in order to determine the price range, it is necessary to carefully observe the market dynamics and refer to the quotations of different manufacturers and different platforms to obtain a more accurate price range. However, it is difficult for me to give you the exact price range at this time.