Tert-butyl 5 '- (3- (3, 5-dichloro-4-fluorophenyl) -4, 4, 4-trifluorobut-2-enoyl) -3' H-spiro [azetidine-3,1 '-isobenzofuran] -1-carboxylate What is the chemical structure of

The Chinese name of this compound is tert-butyl 5 '- (3- (3,5-dichloro-4-fluorophenyl) -4,4,4-trifluorobutyl-2-alkenyl) -3' H-spiro [azacyclobutane-3,1 '-isobenzofuran] -1-carboxylate. To know its chemical structure, listen to me in detail.

The structure of this compound contains several key parts. First, there is tert-butyl, which acts as a "guardian" sitting firmly behind, providing a specific steric barrier and chemical stability for the entire molecular structure. " 5 '- (3- (3,5-dichloro-4-fluorophenyl) -4,4,4-trifluorobutyl-2-alkenyl) "This part is one of the core" warheads "of the molecule. 3,5-dichloro-4-fluorophenyl is like a" sharp blade ", because of the presence of chlorine atoms and fluorine atoms, it endows the molecule with special electronic effects and space effects. And the 4,4,4-trifluorobutyl-2-alkenyl part, trifluoromethyl has strong electron absorption, which changes the electron cloud distribution of the molecule as a whole, and the double bond of the alkenyl group brings certain reactivity.

Furthermore, in the part of "3'H-spiro [azacyclobutane-3,1 '-isobenzofuran] -1-carboxylate", the spiral ring structure is like a unique "bridge", which cleverly connects azacyclobutane and isobenzofuran. Azacyclobutane, as a small heterocyclic ring, has unique ring tension and heteroatomic properties, allowing the molecule to have a different reactivity and spatial structure. Isobenzofuran adds aromaticity to the whole molecule, stabilizing the molecular structure while affecting its physical and chemical properties. The presence of the ester group in the final carboxylic acid ester not only affects the polarity of the molecule, but also becomes a key "breakthrough" in many chemical reactions, which can carry out various reactions such as hydrolysis and alcoholysis.

To sum up, this compound has a complex and delicate structure, and the synergistic structure of each part gives it unique chemical and physical properties, which may have potential application value in the fields of organic synthesis and medicinal chemistry.

Tert-butyl 5 '- (3- (3, 5-dichloro-4-fluorophenyl) -4, 4, 4-trifluorobut-2-enoyl) -3' H-spiro [azetidine-3,1 '-isobenzofuran] -1-carboxylate What are the physical properties of

This is an organic compound called tert-butyl 5 '- (3- (3,5-dichloro-4-fluorophenyl) -4,4,4-trifluorobutyl-2-alkenyl) -3' H-spiro [azacyclobutane-3,1 '-isobenzofuran] -1 -carboxylic acid ester. Its physical properties are unique, and let me tell them one by one.

Looking at its properties, it is often in a solid state, but its melting point needs to be studied in detail. Due to the presence of many special groups in the molecular structure, such as tert-butyl, dichlorofluorophenyl, trifluorobutenyl acyl and spiro ring structures, the intermolecular forces are complex, and the melting point may be significantly affected. This temperature range needs to be determined by precise experiments after theoretical inference, or melting within a specific temperature range.

Its solubility is also interesting. Since the molecule contains both electronegative atoms such as fluorine and chlorine, the molecule has a certain polarity, and there are non-polar alkyl groups such as tert-butyl, it has a unique solubility in organic solvents. In polar organic solvents, such as dichloromethane and acetone, there may be a certain solubility, because the polar part can form a dipole-dipole interaction with the solvent molecule; while in non-polar solvents, such as n-hexane, the solubility may be limited, because although the non-polar alkyl group has a van der Waals force action with the non-polar solvent, the overall molecular polarity hinders its dissolution.

Then talk about its stability. Functional groups such as unsaturated double bonds and carbonyl groups in the molecule make it chemically active. Under the conditions of light, heat or the presence of specific reagents, or a chemical reaction occurs. If the unsaturated double bond is easily attacked by electrophilic reagents, an addition reaction occurs; carbonyl can also participate in nucleophilic addition and other reactions. However, the spiral ring structure and benzene ring in the molecule can provide certain stability, and the electron cloud can be dispersed due to the conjugation effect, reducing the molecular energy.

This density is also an important physical property. Due to the specific types and quantities of atoms in the molecule, its mass and volume have a unique relationship. Although the exact density needs to be determined experimentally, according to the structure, its density may be comparable to that of common organic compounds. The specific value is affected by factors such as the way of molecular accumulation.

In summary, the physical properties of tert-butyl 5 '- (3- (3,5-dichloro-4-fluorophenyl) -4,4,4-trifluorobutyl-2-alkenyl) -3' H-spiro [azacyclobutane-3,1 '-isobenzofuran] -1 -carboxylic acid esters are determined by their complex structures, and their properties are interrelated, affecting their behavior in different environments.

Tert-butyl 5 '- (3- (3, 5-dichloro-4-fluorophenyl) -4, 4, 4-trifluorobut-2-enoyl) -3' H-spiro [azetidine-3,1 '-isobenzofuran] -1-carboxylate What is the synthesis method of

To obtain tert - butyl 5 '- (3 - (3,5 - dichloro - 4 - fluorophenyl) -4, 4, 4 - trifluorobut - 2 - enoyl) -3' H - spiro [azetidine - 3,1 '- isobenzofuran] -1 - carboxylate synthesis method, need to follow the exquisite organic synthesis path. First, carefully select the appropriate starting materials, which is the foundation of the synthesis industry. Optional 3,5 - dichloro - 4 - fluorobenzene and compounds containing alkenyl, carbonyl and other functional groups to lay the basic structure of the molecule.

Then, the wonderful methods of organic chemistry are used, such as nucleophilic substitution reactions, addition reactions, etc. Nucleophilic substitution reactions can make specific functional groups combine with each other to form carbon-carbon bonds or carbon-heteroatomic bonds, just like the tenon-and-mortise method of splicing components. Addition reactions can convert unsaturated bonds into desired structures and enrich the chemical properties of molecules.

Furthermore, for the construction of spiral ring structures, clever cyclization reactions are required. Through reasonable regulation of reaction conditions, such as temperature and catalysts, the atoms in the molecule interact to form a unique spiral [azacyclobutane-3,1 '-isobenzofuran] structure. Among them, the choice of catalyst is crucial, which can speed up the reaction rate and guide the reaction in the desired direction, like a helmsman piloting a ship.

During the synthesis process, the control of the reaction conditions must be precise. The temperature, the length of the reaction time, and the proportion of reactants will all affect the success or failure of the synthesis. If the temperature is too high, the reaction may be out of control and the product will decompose; if the temperature is too low, the reaction will be slow and the efficiency will be low. Therefore, many tests are required to find the best reaction conditions.

The separation and purification of the product after

should not be ignored. Using methods such as column chromatography and recrystallization to remove impurities and obtain a pure target product. The column chromatography can be separated according to the difference in material polarity, and the recrystallization method can purify the product by the difference in solubility. After this series of fine operations, tert-butyl 5 '- (3 - (3,5 - dichloro - 4 - fluorophenyl) -4, 4,4 - trifluorobut - 2 - enoyl) -3' H - spiro [azetidine - 3,1 '- isobenzofuran] -1 - carboxylate can be obtained.

Tert-butyl 5 '- (3- (3, 5-dichloro-4-fluorophenyl) -4, 4, 4-trifluorobut-2-enoyl) -3' H-spiro [azetidine-3,1 '-isobenzofuran] -1-carboxylate What are the application fields?

"Tiangong Kaiwu" is a masterpiece of ancient technology, but the book does not contain "tert - butyl 5 '- (3 - (3,5 - dichloro - 4 - fluorophenyl) - 4,4,4 - trifluorobut - 2 - enoyl) - 3'H - spiro [azetidine - 3,1' - isobenzofuran] - 1 - carboxylate". This compound is the product of modern organic chemical synthesis, with a complex structure and a combination of many specific functional groups.

Today, this compound is widely used in the field of medicinal chemistry. First, it can be used as a key intermediate in drug development. Due to its unique chemical structure, it can participate in a variety of reactions, helping chemists to construct molecules with specific biological activities, laying the foundation for the development of new drugs, such as innovative drugs targeting specific disease targets. Second, in the field of material science, or because of its special physical and chemical properties, it can be used to prepare functional materials, such as materials with special optical and electrical properties, used in electronic devices, optical instruments, etc. Third, in agricultural chemistry, it may be reasonably modified and modified to develop new pesticides, using its regulation of specific biological activities to achieve efficient and low-toxicity pest control. In short, although "Tiangong Kaiwu" is difficult to find, in many fields of modern science and technology, this material has great potential and broad prospects.

Tert-butyl 5 '- (3- (3, 5-dichloro-4-fluorophenyl) -4, 4, 4-trifluorobut-2-enoyl) -3' H-spiro [azetidine-3,1 '-isobenzofuran] -1-carboxylate What is the market outlook?

I have heard your inquiry about the market prospect of tert-butyl 5 '- (3 - (3,5 - dichloro - 4 - fluorophenyl) -4, 4,4 - trifluorobut - 2 - enoyl) -3' H - spiro [azetidine - 3,1 '- isobenzofuran] -1 - carboxylate. This compound has great potential in today's market.

Looking at the field of medicine, the research and development of medicine is advanced at present, and there is a growing demand for compounds with unique structures and activities. The structure of this compound is exquisite, or it has special pharmacological activities, and can be used as a drug lead compound. Nowadays, many pharmaceutical companies and scientific research institutions are dedicated to the research and development of new target drugs. Due to differences in structure, this compound can be combined with specific targets to provide opportunities for the creation of new drugs. Therefore, it is expected to occupy a place in the pharmaceutical research and development market.

The field of pesticides should not be underestimated. Today's agriculture pursues high-efficiency, low-toxicity, and environmentally friendly pesticides. If this compound is properly designed and modified, it may have insecticidal, bactericidal, and herbicide effects. With the rise of green agriculture, there is a strong demand for new pesticides. It may be able to conform to this trend. With its unique chemical structure, it exhibits excellent biological activity and finds room for development in the pesticide market.

However, its market prospects are not smooth sailing. Synthesizing this compound, or the process is complicated and expensive, is a major challenge. If the synthesis route cannot be optimized and the cost is reduced, it may be at a disadvantage in the market competition. And the research and development of new drugs or new pesticides must go through a strict approval process, which takes a long time and requires a lot of investment. It is necessary to overcome many difficulties before it can be approved to enter the market.

In summary, tert - butyl 5 '- (3- (3,5 - dichloro - 4 - fluorophenyl) -4,4,4 - trifluorobut - 2 - enoyl) -3'H - spiro [azetidine - 3,1' - isobenzofuran] -1 - carboxylate has broad market prospects, but it also faces many challenges. It requires concerted efforts from scientific research and industry to fully explore its value.