(S) -tert-butyl 6- (5- (7-bromo-9, 9-difluoro-9H-fluoren-2-yl) -1H-imidazol-2-yl) -5-azaspiro [2.4] What is the chemical structure of heptane-5-carboxylate

The chemical structure of (S) -tert-butyl 6- (5- (7-bromo-9,9-difluoro-9H-fluorene-2-yl) -1H-imidazole-2-yl) -5-azospira [2.4] heptane-5-carboxylate is just like that exquisitely constructed microscopic universe.

Looking at its name, it can be disassembled and analyzed. This compound takes spiro [2.4] heptane as the core structure, which is like the cornerstone of an ancient city, laying the skeleton of the whole. 5-Aza, embedded in nitrogen atoms on the skeleton, such as adding special pavilions in the city to change the properties and activities of the molecule.

Tert-butyl, like a fortress outside the city, is connected to the 5-azospira [2.4] heptane-5-carboxylate, giving the molecule a specific spatial resistance and electronic effects.

Looking at the 6- (5- (7-bromo-9,9-difluoro-9H-fluorene-2-yl) -1H-imidazole-2-yl) part, it is like a complex palace group in the city. 1H-imidazole-2-yl, with its five-membered nitrogen-containing heterocyclic state, injects unique reactivity and coordination ability into the molecule. 5- (7-bromo-9,9-difluoro-9H-fluorene-2-yl), fluorene group is the main body of the palace, and the modification of bromine and difluoro atoms is like a strange gem inlaid on the palace, which affects the electron cloud distribution, solubility and optical properties of the molecule.

The chemical structure of this compound is a microscopic masterpiece carefully designed by chemists. Each part works together to shape the unique chemical and physical properties.

(S) -tert-butyl 6- (5- (7-bromo-9, 9-difluoro-9H-fluoren-2-yl) -1H-imidazol-2-yl) -5-azaspiro [2.4] What are the physical properties of heptane-5-carboxylate

(S) -tert-butyl 6- (5- (7-bromo-9,9-difluoro-9H-fluorene-2-yl) -1H-imidazole-2-yl) -5-azospira [2.4] heptane-5-carboxylate, this is an organic compound. Its physical properties are worth exploring.

Looking at its solubility, this compound has a specific performance in organic solvents. Common organic solvents such as dichloromethane and chloroform have very good solubility. Because the molecular structure of this compound contains hydrophobic aromatic rings and alkyl parts, it is in line with the non-polar properties of the above organic solvents and follows the principle of "similarity and compatibility". However, in water, its solubility is negligible, and it is difficult to form effective interactions with water molecules due to the weak polarity of the overall structure.

In terms of melting point, it has been accurately determined to be in a specific temperature range. The intermolecular forces of this compound, such as van der Waals forces, hydrogen bonds, etc., jointly determine its melting point. The π-π accumulation of aromatic rings in the molecule enhances the intermolecular attraction and maintains the melting point at a certain height.

In addition to its appearance, it usually appears as a white to off-white solid powder. This morphology is related to its molecular arrangement and crystallization habits. The molecules are arranged in an orderly manner in the crystal lattice to form a specific crystal structure, which is macroscopically presented as powder. And the compound has certain stability. Under conventional storage conditions, its chemical properties are relatively stable, and it is not prone to significant deterioration or decomposition reactions, which benefits from the inherent stability of its molecular structure.

(S) -tert-butyl 6- (5- (7-bromo-9, 9-difluoro-9H-fluoren-2-yl) -1H-imidazol-2-yl) -5-azaspiro [2.4] What is the synthesis method of heptane-5-carboxylate

To prepare (S) -tert-butyl 6- (5 - (7 - bromo - 9,9 - difluoro - 9H - fluorene - 2 - group) - 1H - imidazole - 2 - group) - 5 - azathione [2.4] heptane - 5 - carboxylic acid ester, the method is as follows:
First, all raw materials need to be prepared, such as fluorene, imidazole, azathione and other related compounds containing specific substituents, and their purity and quality need to be ensured. < Br > In the reaction kettle, dissolve the starting material with a suitable organic solvent, such as dichloromethane, N, N-dimethylformamide, etc. Add an appropriate amount of alkali, such as potassium carbonate, triethylamine, etc., to adjust the pH of the reaction environment, which is conducive to the reaction.
Then, slowly add halogenated reagents, such as bromine-containing halogens. During this process, the reaction temperature and rate should be closely monitored. The temperature may be maintained at a low temperature, such as 0 ° C to 10 ° C, to prevent side reactions. After fully stirring the reaction, the raw materials are fully contacted and reacted.
After the reaction is completed, extract the reaction mixture with an appropriate extractant, such as ethyl acetate, ether, etc., and separate the target product from the reaction system. Repeat with water washing, drying and other steps to remove impurities and obtain a crude product. At the end of column chromatography, suitable silica gel and eluent, such as petroleum ether and ethyl acetate mixture, the crude product was purified, the eluent containing the target product was carefully collected, and the solvent was evaporated to obtain purified (S) -tert-butyl 6- (5- (7-bromo-9,9-difluoro-9H-fluorene-2-yl) -1H-imidazole-2-yl) -5-azospira [2.4] heptane-5-carboxylate. Every step requires careful attention in order to achieve the desired product.

(S) -tert-butyl 6- (5- (7-bromo-9, 9-difluoro-9H-fluoren-2-yl) -1H-imidazol-2-yl) -5-azaspiro [2.4] What are the application fields of heptane-5-carboxylate

(S) -tert-butyl 6- (5- (7-bromo-9,9-difluoro-9H-fluorene-2-yl) -1H-imidazole-2-yl) -5-azospira [2.4] heptane-5-carboxylate, this compound may have important uses in pharmaceutical research and development, organic synthesis and other fields.

In the field of pharmaceutical research and development, or can be used as a lead compound. Its unique molecular structure contains specific aromatic rings and heterocyclic structures, or can be closely bound to specific targets in organisms, such as proteins, enzymes, etc. It is like a precise arrow hitting the bullseye, and through the interaction with the target, it regulates specific physiological processes in organisms. If the compound binds to disease-related proteins, it may regulate the disease process and lay the foundation for the creation of new drugs.

In the category of organic synthesis, it can be used as a key intermediate. With its complex and unique structure, chemists can use a variety of organic reactions to ingeniously modify and expand its structure. It is like building a delicate building block, on which to build more complex and diverse organic molecules, enrich the types of organic compounds, and provide more material bases for materials science, pharmaceutical chemistry and other fields. And because it contains special functional groups such as bromine atoms and fluorine atoms, it can participate in many halogenation reactions, introduce new chemical properties and functions for molecules, and expand the boundaries of organic synthesis.

(S) -tert-butyl 6- (5- (7-bromo-9, 9-difluoro-9H-fluoren-2-yl) -1H-imidazol-2-yl) -5-azaspiro [2.4] What is the market outlook for heptane-5-carboxylate

(S) -tert-butyl 6- (5- (7-bromo-9,9-difluoro-9H-fluorene-2-yl) -1H-imidazole-2-yl) -5-azospira [2.4] heptane-5-carboxylate, the current market prospect of this compound is the focus of much debate.

Looking at the field of chemistry and medicine today, the research and development of new compounds seems to be shining brightly and changing with each passing day. This compound has a unique structure, in which 7-bromo-9,9-difluoro-9H-fluorene-2-group and imidazole, azospirulina and other structural fragments are intertwined, giving it potential biological activity.

In the path of drug development, many pharmaceutical companies and scientific research institutes are committed to finding lead compounds with high efficiency and low toxicity. This compound may target specific biological targets due to its unique structure, and has made a name for itself in the treatment of many diseases such as anti-tumor, anti-inflammatory, and neurological diseases. For example, in terms of anti-tumor, it may be able to inhibit the proliferation of tumor cells and induce their apoptosis by interacting with specific proteins of tumor cells, thus opening up a new path for the development of new anti-cancer drugs.

In the field of materials science, it also has potential applications. Because it contains a special fluorofluorene-based structure, or endows the material with unique optical and electrical properties, it plays a key role in the fabrication of organic Light Emitting Diode (OLED), field-effect transistor (FET) and other devices to improve the performance and stability of the device.

However, its market prospect is not smooth. The complexity of the synthesis process is the first problem. To achieve large-scale, high-purity synthesis requires a lot of manpower and material resources to optimize the synthesis route and reduce production costs. Furthermore, the verification of biosafety and effectiveness also requires a long and rigorous clinical trial process, and only through rigorous evaluation can it be recognized by the market.

In summary, (S) -tert-butyl 6- (5- (7-bromo-9,9-difluoro-9H-fluorene-2-yl) -1H-imidazole-2-yl) -5-azospira [2.4] heptane-5-carboxylate is facing challenges, but its potential in the field of drugs and materials makes its market prospects full of opportunities and hope, just like the dawn before dawn, although hazy but contains infinite possibilities.