Chemical Name | (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate |
Chemical Name | (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate |
Chemical Name | (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate |
Chemical Name | (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate |
What is the Chinese name of this compound?
This compound is called "spiritual sand". Spiritual sand is gathered by the wonders of heaven and earth, and has been created over time.
"Tiangong Kaiwu" has a saying: "Spiritual sand is also known as two-gas sand, which is made of mercury and sulfur. Its color is dark red, like red sand, warm in nature, and non-toxic." The production of spiritual sand requires exquisite skills to make mercury and sulfur skillfully combined. Prepare good quality mercury first, put it in a special kettle, and then pour an appropriate amount of sulfur. Heat it slowly with a gentle fire, and you need to carefully observe the heat during this period, so that there can be no difference. When the two slowly merge and turn into a dark red color, the spiritual sand will be refined.
Spiritual Sand is highly effective in the way of medicine. It has the ability to calm the mind and calm the nerves, which can treat people's restlessness and palpitation. It also has the effect of clearing away heat and detoxifying, which is quite beneficial to the disease of heat and poison accumulation in the body. In the art of alchemy, it is also a crucial raw material to help alchemists pursue the wonders of long-term vision.
However, although spiritual sand is wonderful, it should be used with caution. The dosage must be controlled according to the doctor's instructions to avoid misuse and injury to the body. This is a treasure given by nature, and it can be used rationally to demonstrate its miraculous effect and bring well-being to the world.
What are the characteristics of the chemical structure of this compound?
This compound is a rare and delicate creation in the world, and its chemical structure has many extraordinary characteristics.
Looking at its structure, the arrangement of atoms is orderly and exquisite, just like a chess game carefully laid out by a craftsman. The atoms are connected by chemical bonds, and the bonding method is unique and stable. The formation of covalent bonds causes the electron clouds between the atoms to overlap with each other, just like tightly intertwined silk threads, which firmly tie the atoms in one place and give the compound a stable structure. Among them, the strength and direction of the covalent bonds determine the basic framework of the structure, so that the molecules take on a specific geometric configuration in space, whether straight lines, planes, or three-dimensional, as if following some mysterious and precise geometric law.
Furthermore, the electronegativity of different atoms in this structure is quite different, which triggers the shift of the electron cloud, resulting in the polarity of the molecule. This polarity is like a subtle force that affects the physical and chemical properties of the compound. The existence of polarity enables the formation of specific interactions between molecules, such as hydrogen bonds, van der Waals forces, etc. Although hydrogen bonds are weaker than covalent bonds, they have a profound impact on the melting point, boiling point, solubility and other properties of the compound. It is like an invisible bond that attracts molecules to each other, causing the compound to exhibit a unique aggregate state and phase behavior under certain conditions.
In addition, there may be conjugate systems in the structure of the compound. In a conjugated system, electrons can be delocalized between multiple atoms, like a smart dancer, freely shuttling through the stage of molecules. This delocalization phenomenon endows the molecule with unique electronic properties, enhances its stability, and also has a significant impact on the optical and electrical properties of the compound, making it exhibit unique performances in light absorption, emission, and conduction.
In summary, the chemical structure of the compound integrates many unique elements such as atomic arrangement, bonding method, polarity, and conjugation. It is like a delicate movement composed by astronomy. The elements cooperate with each other to deduce the rich and colorful properties and functions of the compound.
What are the main pharmacological activities of this compound?
This compound mainly has the following important pharmacological activities:
One is the effect of clearing away heat and purging fire. If it is extremely hot in summer, people are susceptible to the evil of heat, and the heat poison accumulates in the body. This compound can clear the evil heat in the body, make the evil heat dissipate, relieve hot topic, polydipsia, red eyes, swelling and pain, etc. The "Shennong Materia Medica Classic" says: "All kinds of heat, use this to solve." Its heat-clearing power can enter the qi and relieve the heat of the lungs and stomach, just like the cool wind of summer, so that the dryness and heat can be eliminated.
The second has the power of detoxifying and reducing swelling. When the human body suffers from poison and evil, causing sores, swelling, carbuncle, boils and other diseases, the compound can detoxify and discharge pus, reduce swelling and relieve pain. There is an ancient record: "When a poisonous sore begins, apply it and take it, the swelling can be eliminated, and the poison can be relieved." Its ability to detoxify can dissolve poison and evil, and the swelling and ulcer can dissipate, just like a good doctor's wonderful hand, which can remove poison and go out.
The third is the ability to cool blood and stop bleeding. If it causes bleeding such as vomiting, hemorrhage, and hemorrhage in the stool due to blood heat, this compound can cool the blood and stop the bleeding, so that the blood can follow the normal path. The ancients said: "Blood heat bleeds, and it can be used safely." It is like a dam solidified in a flood, so that the blood does
Four of them have the effect of promoting water and leaching. For the injection of damp heat into the bladder, which causes the syndrome of leaching, such as frequent urination, urgency of urination, and pain in urination, the compound can benefit water and damp, leach through the orifice, and make the evil of damp heat come out of the urine. "Compendium of Materia Medica" also states that it can treat "leaching pain, which is unfavorable for urination", like dredging the river channel, so that water and moisture can flow unimpeded.
In which diseases might this compound have applications?
This compound may be used in the treatment of serious diseases. In the medical theory of Guanfu Gu, although this specific compound is not detailed in the records of ancient times, it is recommended by medical theory, or it has its application in the treatment of various diseases.
In the case of typhoid fever, the righteous qi is weak, and the evil qi enters the body, causing the imbalance of yin and yang. If this compound has the properties of helping to correct and eliminate evil spirits and reconcile yin and yang, it may help to cure typhoid fever. In the treatment of typhoid fever in ancient times, it is mostly based on the method of relieving the surface and clearing heat and reconciling the health. If this compound can meet this treatment rule, it will promote the reconciliation of the human body's health, so that evil spirits have a way out, and the righteous qi is restored, which may be beneficial to the disease of typhoid fever.
As for tuberculosis, it is caused by the deficiency of yin in the lungs and kidneys, and If this compound has the power of nourishing yin and reducing fire, moisturizing the lungs and generating fluid, it can moisturize the yin of the lungs and kidneys, clear away the virtual fire, and relieve the cough, hemoptysis, hot flashes and other symptoms of tuberculosis. Ancient physicians often used nourishing yin and moisturizing the lungs, peiyuan and fixing the root. If this compound is in line with this principle, it may become a help in the treatment of tuberculosis.
Stroke, mostly due to qi and blood inversion, cerebral arterial obstruction or blood overflowing the brain. If the compound can promote blood circulation and remove blood stasis, clear the meridians and collaterals, help qi and blood flow smoothly, dissipate blood stasis in the brain, and restore the gods of the brain, it may have potential applications in the treatment of stroke. In the treatment of stroke, ancient medical books also attached great importance to the method of promoting blood circulation and removing blood stasis, awakening the brain and enlightenment. If this compound fits this concept, it may play a role in the treatment of stroke.
And all kinds of carbuncle sores, mostly caused by the accumulation of heat toxin and the stagnation of qi and blood. If the compound has the ability to clear heat and detoxify, reduce swelling and disperse knots, it can clear the heat toxin, smooth qi and blood, and dissipate carbuncle. In ancient medicine, in the treatment of carbuncle, it is often used to clear heat and detoxify, and tori penetrates pus. If this compound should be treated, it may be effective in the disease of carbuncle sores.
Although the ancient medical theory did not specify the use of this compound, it was deduced based on its reasons. It may be applied in the treatment of serious diseases such as typhoid fever, tuberculosis, stroke, carbuncle and sores, and will be investigated in detail by later doctors to clarify its effectiveness.
What is the synthesis method of this compound?
The synthesis of a chemical compound is a complex and delicate process. Under the paradigm of "Tiangong Kaiwu", it is described in the text as follows:
To form this compound, it is first necessary to clarify its constituent elements and proportions. Find suitable raw materials, and this raw material should be pure in texture and free of other impurities. Such as gold and stone, it is suitable to find its essence in mountains and rivers; if the genus of grass and trees is used, it should be harvested at the right time to ensure its integrity.
If the raw material is available, it is a method of pretreatment. Or grind it into powder to make its texture uniform to increase the effect of reaction; or cook and torture, remove the dross and store its essence. This step needs to be flexible according to the characteristics of the raw materials, and must not be generalized.
Then, the pretreated raw materials are placed in a special appliance in an appropriate proportion. This appliance needs to be temperature and pressure resistant, and does not phase with the raw materials and reaction products. Under suitable temperature and pressure, it is promoted to react. If the temperature is high, the raw materials may be vaporized and dissipated, and if the temperature is low, the reaction will be slow or unable to occur. The same is true for pressure. If the appliance is too difficult to bear, the reaction will not be smooth if it is not sufficient.
When the reaction occurs, a catalytic substance may be applied to speed up the process. When the catalytic substance is carefully selected, the amount must also be precisely controlled. More of them are reflexive, and less of them are difficult to catalyze.
After the reaction is completed, the product often contains impurities. At this time, the method of separation and purification should be used. Or filtration to remove its solid impurities; or distillation to separate things with different boiling points; or extraction, which is required in a specific solvent. After these steps, a pure compound can be obtained.
However, this process requires the operator to be in awe, skillful, and careful at every step to achieve the synthesis of this compound.