4 4 Trans 3 4 Difluorophenyl Cyclohexyl Cyclohexanone
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
4-[4-trans-(3,4-Difluorophenyl)-cyclohexyl]-cyclohexanone
Chemical Name 4-[4-trans-(3,4-Difluorophenyl)cyclohexyl]cyclohexanone
Molecular Formula C18H22F2O
Molecular Weight 292.36
Appearance Solid (predicted)
Boiling Point Estimated around 379.8°C at 760 mmHg
Solubility Insoluble in water, soluble in organic solvents like dichloromethane
Logp Estimated around 5.5 (lipophilic)
Density Estimated around 1.11 g/cm³
Vapor Pressure Very low, estimated in the range of 10^-6 mmHg at 25°C
Chemical Formula C18H22F2O
Molecular Weight 292.363
Appearance Solid
Solubility In Water Low
Solubility In Organic Solvents Moderate
Vapor Pressure Low
Chemical Formula C18H22F2O
Molecular Weight 292.363
Physical State Solid (predicted)
Boiling Point 384.3°C at 760 mmHg (predicted)
Melting Point 98 - 102°C
Flash Point 160.3°C (predicted)
Density 1.134 g/cm³ (predicted)
Logp 5.24 (predicted)
Solubility Insoluble in water (predicted)
Vapor Pressure 2.49E-06 mmHg at 25°C (predicted)
Chemical Formula C18H22F2O
Molecular Weight 292.36
Appearance Solid (usually)
Melting Point Data needed
Boiling Point Data needed
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Density Data needed
Flash Point Data needed
Stability Stable under normal conditions, avoid strong oxidizing agents
FAQ

What are the main application fields of 4- [4-trans- (3,4-difluorophenyl) cyclohexyl] cyclohexanone

4 - [4 - trans - (3,4 - dihydrophenyl) cyclohexyl] cyclohexanone, this substance has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to help develop many drugs. Due to its unique chemical structure, it can participate in a variety of chemical reactions. After ingenious design and transformation, it can generate compounds with specific pharmacological activities, which can be used for disease treatment and prevention.

In the field of materials science, it also has its own shadow. By virtue of its own properties, it can be integrated into specific material systems to improve material properties, such as enhancing material stability and adjusting material physical properties, providing possibilities for the creation of new materials.

In the field of organic synthesis, it is an important cornerstone. Chemists can use it to build complex organic molecular structures and expand the types and functions of organic compounds. By carefully planning reaction paths, combining various organic reactions, and using them as starting materials, organic molecules with complex structures and specific functions can be gradually constructed, contributing to the development of organic synthetic chemistry. In short, 4- [4-trans - (3,4-dihydrophenyl) cyclohexyl] cyclohexanone has important application value in many fields such as medicine, materials, and organic synthesis, and plays a key role in progress and innovation in various fields.

What are the synthesis methods of 4- [4-trans- (3,4-difluorophenyl) cyclohexyl] cyclohexanone

To prepare 4 - [4 - trans - (3,4 - dihydrophenyl) cyclohexyl] cyclohexanone, there are various methods.

One is to use common cyclic compounds as starting materials and undergo a multi-step reaction. First, a cyclic alkene is added to a specific electrophilic reagent. This step requires precise control of the reaction conditions, such as temperature and solvent selection, to ensure that the addition check point is accurate. After the addition product is reduced, a suitable reducing agent is selected, and the unsaturated bond is converted into a saturated bond under a suitable environment. Subsequently, the desired cyclic structure is constructed by ingenious intramolecular cyclization reaction. In this process, the choice and amount of catalyst are crucial, which is related to the efficiency and selectivity of cyclization.

The second method can start from compounds with similar structures and achieve functional group conversion and skeleton modification. Beginning with benzene derivatives containing appropriate substituents, cyclohexyl-containing fragments are introduced through alkylation reaction. Pay attention to the activity and reaction sequence of alkylating reagents during the reaction. After that, the benzene ring is reduced and hydrogenated to convert to a dihydrophenyl structure. Then through a series of operations such as oxidation and cyclization, the ketone group and overall structure of the target molecule are shaped. Each step needs to be carefully regulated to avoid the growth of side reactions.

Third, bionic synthesis strategies can also be considered. Simulate the mechanism of the formation of similar compounds in nature, and use enzymes or enzyme models to catalyze the reaction. This method can improve the selectivity and atomic economy of the reaction, but the reaction system requires strict requirements. It is necessary to simulate the mild reaction conditions in the organism, and precisely control the pH, temperature and substrate concentration to make the enzyme exert the best catalytic efficiency, so as to efficiently synthesize 4- [4-trans-- (3,4-dihydrophenyl) cyclohexyl] cyclohexanone.

What is the market outlook for 4- [4-trans- (3,4-difluorophenyl) cyclohexyl] cyclohexanone?

Guanfu 4 - [4 - trans - (3,4 - dihydrophenyl) cyclohexyl] cyclohexanone is worth exploring in the current market prospect.

This product may have extraordinary potential in the field of pharmaceutical and chemical industry. In recent years, the rise of pharmaceutical research and development has led to the increasing search for characteristic organic compounds. Such a special ring structure may be a key building block for new drug molecules. Due to its unique spatial configuration and electron cloud distribution, it can be well matched with specific targets in organisms, and then it is expected to develop innovative drugs with excellent efficacy and few side effects.

In the field of materials science, there are also opportunities. With the development of high-tech, the need for materials with special properties is increasing. This compound may be reasonably modified to prepare functional materials with special optical and electrical properties, such as organic optoelectronic materials, which will contribute to the progress of display technology and optoelectronic devices.

However, its marketing activities are not smooth. The complexity of the synthesis process is a major obstacle. To achieve large-scale production, it is necessary to optimize the synthesis route, improve yield and reduce costs. And market awareness needs to be improved, and many potential application fields have not yet been deeply understood and studied.

In summary, the market prospect of 4 - [4 - trans - (3,4 - dihydrophenyl) cyclohexyl] cyclohexanone, although opportunities and challenges coexist, will be able to bloom in the fields of medicine and materials and open up a new world with the breakthrough of synthesis technology and the effectiveness of marketing activities over time.

What are the physicochemical properties of 4- [4-trans- (3,4-difluorophenyl) cyclohexyl] cyclohexanone?

4 - [4 - trans - (3,4 - dihydrophenyl) cyclohexyl] cyclohexanone, the physical and chemical properties of this substance are particularly important. Its shape can be judged from the point of view of whether it is a crystalline state or an oily liquid.

Discusses the melting point, which is related to the key temperature of its physical state transformation. However, the exact value can only be determined by precise experiments, or it varies depending on the preparation method and purity.

The boiling point is also an important characterization. Under a specific pressure, the temperature at which a substance converts from a liquid state to a gaseous state. To know the details, rigorous experiments are also required. < Br >
In terms of solubility, it may have different performances in common organic solvents, such as ethanol and ether. Ethanol, with a certain polarity, if the substance interacts with it appropriately, or is soluble; ether, with a slightly different polarity, solubility is also a different matter. In water, due to the strong polarity of water, and if there is no strong hydrophilic group in the structure of this substance, it may be difficult to dissolve.

Its chemical properties, due to the presence of ketone groups in the molecular structure, have a typical reaction of carbonyl groups. Addition can occur with nucleophiles, such as Grignard reagents, carbon-magnesium bonds attack carbonyl-carbon nucleophiles, generate new carbon-carbon bonds, and derive other compounds. And because of its benzene ring-related structure, although it is not a typical benzene ring, it may have some properties similar to aromatic hydrocarbons, such as substitution reaction under specific conditions.

The physicochemical properties of this substance are of great significance in many fields such as organic synthesis and drug research and development. In organic synthesis, reaction paths can be designed according to its properties to prepare more complex and delicate compounds; in drug development, or due to the interaction with biomolecules, it is expected to become a potential active ingredient, but more in-depth research and exploration are required.

What are the precautions for 4- [4-trans- (3,4-difluorophenyl) cyclohexyl] cyclohexanone during storage and transportation?

4 - [4 - trans - (3,4 - dihydrophenyl) cyclohexyl] cyclohexanone, during storage and transportation, it is necessary to pay attention to many matters.

First, the nature of this material may have special characteristics, when avoiding open flames and hot topics. Because it is easy to cause combustion in case of open flames, hot topic environment may also cause its chemical properties to change, and even the risk of explosion. Therefore, the storage place must be a cool and well-ventilated place, away from fire and heat sources, to ensure environmental safety.

Second, packaging should not be ignored. Appropriate packaging materials should be selected and tightly sealed to prevent its leakage. Packaging needs to be able to withstand certain external forces to avoid damage due to collision and extrusion during transportation, resulting in material leakage, which is not only wasteful but also causes pollution to the surrounding environment, and even endangers the safety of personnel.

Third, during transportation, the transportation tool needs to be clean and dry, and there are no other impurities that may react with it. During loading and unloading, the operator must handle it with care, and must not operate it brutally to prevent damage to the packaging. At the same time, the transportation route planning should also be prudent, avoiding crowded areas and important facilities. If leakage occurs unfortunately, the degree of harm can be reduced.

Fourth, the storage place should be equipped with corresponding fire equipment and leakage emergency treatment equipment. In the event of an accident, rescue and treatment can be carried out in time to minimize losses. And the storage area needs to have obvious warning signs to warn personnel of its danger and increase everyone's vigilance.

In summary, during the storage and transportation of 4 - [4 - trans - (3,4 - dihydrophenyl) cyclohexyl] cyclohexanone, all details must be strictly treated, and there must be no slack to ensure the safety of personnel, the environment is not polluted, and the materials are intact.