4 4 3 4 Difluorophenyl Cyclohexyl Cyclohexanone
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
4-[4-(3,4-Difluorophenyl)-cyclohexyl]-cyclohexanone
Chemical Name 4-[4-(3,4-Difluorophenyl)cyclohexyl]cyclohexanone
Molecular Formula C18H22F2O
Molecular Weight 292.363 g/mol
Logp Estimated logP would suggest it has some lipophilic character due to the cyclohexyl and phenyl groups, but no exact value given
Chemical Formula C18H22F2O
Molar Mass 292.363 g/mol
Appearance Solid (predicted)
Boiling Point Estimated around 385 - 390 °C
Density Estimated around 1.1 - 1.2 g/cm³ (predicted)
Solubility In Water Low solubility, hydrophobic nature
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Flash Point Estimated around 160 - 170 °C
Vapor Pressure Very low vapor pressure at room temperature
Stability Stable under normal conditions, may react with strong oxidizing agents
Chemical Formula C18H22F2O
Molecular Weight 292.36
Appearance Solid (usually)
Boiling Point Estimated high temperature due to large molecular structure
Melting Point Specific value would require experimental determination
Density Needs experimental measurement
Solubility In Water Low solubility, being an organic compound with non - polar groups
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure Low vapor pressure at normal conditions
Flash Point Requires experimental determination
Stability Stable under normal conditions but may react with strong oxidizing agents
Chemical Formula C18H20F2O
Molecular Weight 290.35
Appearance Solid (predicted)
Boiling Point Estimated around 380 - 400 °C
Melting Point Estimated in a certain range (data may vary)
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Density Estimated density value (approximate)
Vapor Pressure Low vapor pressure at ambient conditions
Logp Positive value indicating lipophilic nature
FAQ

What is the main use of 4- [4- (3,4-difluorophenyl) cyclohexyl] cyclohexanone?

4- [4- (3,4-diethylamino) cyclohexyl] cyclohexanone, which has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate and plays an important role in the development of specific drugs. For example, some drugs used to regulate the function of the nervous system, during the synthesis process, 4- [4- (3,4-diethylamino) cyclohexyl] cyclohexanone can be converted into structural units with specific pharmacological activities through a series of chemical reactions, helping the drug achieve the desired therapeutic effect.

In the field of organic synthesis, it is an important cornerstone for the construction of complex organic molecules. With its unique chemical structure, it can participate in various types of reactions, such as nucleophilic substitution, addition, etc., to achieve ingenious construction and modification of the molecular structure of organic compounds, laying the foundation for the synthesis of organic materials with novel structures and characteristics.

In the field of materials science, polymer materials with special properties can be prepared from this raw material. For example, by polymerizing with other monomers, polymer materials are endowed with unique solubility, thermal stability or mechanical properties, etc., to meet the strict requirements for special properties of materials in different fields such as electronic devices, aerospace, etc.

In summary, 4- [4- (3,4-diethylamino) cyclohexyl] cyclohexanone plays an indispensable role in many important fields due to its diverse uses, and is of great significance to promoting technological progress and innovation in related fields.

What are the synthesis methods of 4- [4- (3,4-difluorophenyl) cyclohexyl] cyclohexanone

The synthesis of 4- [4- (3,4-diethylphenyl) cyclohexyl] cyclohexanone is a key issue in the field of organic synthesis. Although the synthesis method is not described in detail in "Tiangong Kaiji", according to the concept of modern organic synthetic chemistry, it can be considered from the following ways.

First, halogenated aromatics and olefins are used as starting materials to form carbon-carbon bonds through Fu-gram alkylation. If an appropriate halogenated benzene derivative is selected with 3,4-diethylstyrene, under the catalysis of Lewis acid catalysts such as aluminum trichloride, a Fu-gram alkylation reaction occurs to generate 3,4-diethylphenyl substituted aromatics. Subsequent cyclization reaction, such as under specific conditions, with a suitable oxidant and catalyst, promotes the cyclization of aromatic hydrocarbons to form a cyclohexyl structure, and then a ketone carbonyl is introduced through a carbonylation reaction to obtain the final target product.

Second, the cyclohexanone derivative is used as the starting material. Cyclohexanone is first modified, such as introducing a halogen atom at a specific position through a halogenation reaction. Then it undergoes a nucleophilic substitution reaction with a nucleophile containing 3,4-diethylphenyl to form a cyclohexanone derivative containing 3,4-diethylphenyl. After a series of reactions such as reduction and cyclization, the molecular structure is adjusted to meet the structural requirements of 4 - [4 - (3,4 - diethylphenyl) cyclohexyl] cyclohexanone. In this process, the reaction conditions, such as temperature, pH, and the type and amount of catalyst, need to be carefully controlled to ensure the selectivity and yield of the reaction.

Third, the Diels-Alder reaction can be used. Select suitable conjugated dienes and dienes, such as 3,4 - diethylphenyl-containing dienes and conjugated dienes, and the Diels-Alder reaction occurs under heating or lighting conditions to construct a six-membered cyclic structure. After that, the obtained product undergoes functional group transformation, such as oxidation, reduction, substitution and other reactions, and gradually introduces the required functional groups to finally synthesize the target compound. This method requires clever design of the reactant structure to take advantage of the regioselectivity and stereoselectivity of the Diels-Alder reaction to efficiently synthesize the target product.

What is the market outlook for 4- [4- (3,4-difluorophenyl) cyclohexyl] cyclohexanone?

4 - [4 - (3,4 - diethylphenyl) cyclohexyl] cyclohexanone, this is an organic compound. Looking at its market prospects, it needs to be considered from many aspects.

First, in the chemical industry, with the continuous expansion of the chemical industry, the demand for various organic raw materials is increasing. This compound may have key uses in the synthesis of special polymers, high-performance materials, etc. Such as the preparation of polymer materials with specific structures and properties, to supply basic materials for high-end fields such as electronics and aerospace. If the chemical industry develops in the direction of high-end and refinement, its market demand is expected to rise steadily.

Furthermore, in terms of pharmaceutical chemistry, organic compounds are often important intermediates in drug synthesis. If the structure of this compound can meet the needs of drug molecular design, it can be used in the process of new drug research and development, or serve as a key building block to help synthesize molecules with specific pharmacological activities. With the accelerated pace of pharmaceutical innovation, the demand for novel and efficient intermediates will also increase, opening up a broad market space for it.

However, its market prospects are also constrained by many factors. Environmental protection policies are one of them. The chemical production process is prone to pollutant emissions. If environmental protection standards become stricter, manufacturers need to invest more resources in pollution prevention and control, or lead to rising production costs, which will affect the market competitiveness of products. And new synthesis methods and alternative products continue to emerge. If there are better synthesis paths or better performance alternatives come out, the market share of this compound may be eroded.

To sum up, the market prospect of 4- [4- (3,4-diethylphenyl) cyclohexyl] cyclohexanone has both opportunities and challenges. Driven by the development of the chemical and pharmaceutical industries, there may be some market demand; however, environmental protection policies and competition trends also need to be carefully responded by enterprises in order to seek development in the market.

What are the physical and chemical properties of 4- [4- (3,4-difluorophenyl) cyclohexyl] cyclohexanone

4- [4- (3,4-diethylamino) cyclohexyl] cyclohexanone, this substance is an organic compound, and its physical and chemical properties are quite characteristic.

Looking at its physical properties, under room temperature, it is mostly in a liquid state and has a certain fluidity. As for the color, it is either colorless and transparent, or slightly yellow, just like water or the color of the first blooming stamens. Its smell is like a light fragrance, but it is hidden in the air. It needs to be smelled carefully to be detectable, just like the fragrance of mountains and forests. Its density is slightly larger than that of water, just like a stone entering the water, sinking steadily, and placed in the water. It can be seen that it is lying quietly at the bottom of the water.

When it comes to chemical properties, this compound contains specific functional groups, so it is quite reactive. The carbonyl group in it is like an active stage for chemical reactions, which can dance with many nucleophiles and stage a wonderful drama of addition reactions. The surrounding alkyl structure, although seemingly stable, can also participate in the substitution reaction under specific conditions, just like a hidden role behind the scenes, showing its skills in a timely manner. Because its structure contains nitrogen atoms, the lone pair of electrons on the nitrogen atom is like a keen antenna, so that the compound can reveal its unique acid-base properties in a specific acid-base environment, just like a wise man, who can respond flexibly in different situations. In the field of organic synthesis, this compound is like a skilled craftsman and is often used as a key intermediate, contributing to the construction of more complex and delicate organic molecules.

In which fields is 4- [4- (3,4-difluorophenyl) cyclohexyl] cyclohexanone used?

4- [4- (3,4-diethylphenyl) cyclohexyl] cyclohexanone, this substance has applications in many fields.

In the field of medicinal chemistry, it can be used as an important intermediate in organic synthesis. In the process of synthesizing some drug molecules with specific physiological activities, with its unique chemical structure, it can impart a specific spatial configuration and electronic effect to the drug molecule, which in turn affects the binding ability and effect of the drug to the target. For example, in the development of innovative drugs for the treatment of cardiovascular diseases or neurological diseases, it may be used as a key starting material or intermediate to construct complex drug molecular structures with precise drug effects through a series of chemical transformations.

The field of materials science also has its own impact. Because of its rigidity and stability, it can be used to prepare high-performance polymer materials. When preparing special engineering plastics, introducing them into the main or side chains of polymers can improve the mechanical properties of materials, such as enhancing the hardness, wear resistance and thermal stability of materials. Like high-performance structural materials used in the aerospace field, polymer materials based on this substance may be included for molecular design and synthesis to meet the stringent requirements of aircraft in extreme environments.

In the fragrance industry, it can add unique aroma characteristics to fragrances. Due to the special odor produced by its molecular structure, it can be used to prepare perfumes, flavors and other products with novel fragrances after proper preparation. For example, in the formulations of some high-end perfumes, such substances will be skillfully used to give perfumes a unique charm and layering, making them unique in the market.

In addition, in the field of organic optoelectronic materials, its application potential may also be found. With the rapid development of organic electronics, the demand for organic compounds with specific optoelectronic properties is growing. 4- [4- (3,4-diethylphenyl) cyclohexyl] cyclohexanone may have certain photoelectric conversion or charge transport properties due to its structural characteristics, and is expected to be applied to organic Light Emitting Diode (OLED), organic solar cells and other devices Preparation, providing new material options for technological innovation in related fields.